IL1 receptor accessory protein like, a protein involved in X-linked mental retardation, interacts with Neuronal Calcium Sensor-1 and regulates exocytosis

Human Molecular Genetics

Volumn 12, Issue 12, 2003, Pages 1415-1425

  Bahi, Nadia ^a   Friocourt, Gaelle ^a   Carrié, Alain ^a   Graham, Margaret E ^b   Weiss, Jamie L ^b   Chafey, Philippe ^a   Fauchereau, Fabien ^a   Burgoyne, Robert D ^b   Chelly, Jamel ^a  

^a INSTITUT COCHIN   (France)

^b UNIVERSITY OF LIVERPOOL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; CALCIUM; CALCIUM BINDING PROTEIN; IMMUNOGLOBULIN; INTERLEUKIN 1; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 1 RECEPTOR ACCESSORY PROTEIN LIKE; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; RECOMBINANT PROTEIN; TOLL LIKE RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; CELL STRAIN; CELLULAR DISTRIBUTION; COGNITIVE DEFECT; CONTROLLED STUDY; EXOCYTOSIS; GENE MUTATION; GENE OVEREXPRESSION; GENETIC CONSERVATION; HUMAN; HUMAN CELL; MENTAL DEFICIENCY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN DEFECT; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; SEQUENCE HOMOLOGY; X CHROMOSOME LINKED DISORDER;

AMINO ACID SEQUENCE; ANIMALS; CALCIUM; CALCIUM SIGNALING; CALCIUM-BINDING PROTEINS; CERCOPITHECUS AETHIOPS; CHO CELLS; COS CELLS; CRICETINAE; EXOCYTOSIS; GROWTH HORMONE; HUMANS; INTERLEUKIN-1; INTERLEUKIN-1 RECEPTOR ACCESSORY PROTEIN; MENTAL RETARDATION, X-LINKED; MOLECULAR SEQUENCE DATA; NERVE TISSUE PROTEINS; NEURONAL CALCIUM-SENSOR PROTEINS; NEUROPEPTIDES; PC12 CELLS; RATS; RECEPTORS, INTERLEUKIN-1; RECOMBINANT PROTEINS; SACCHAROMYCES CEREVISIAE; SEQUENCE HOMOLOGY, AMINO ACID; TWO-HYBRID SYSTEM TECHNIQUES;

ANIMALIA; MAMMALIA;

EID: 0038377518     PISSN: 09646906     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (46)

1. Moser, H., Ramey, C. and Leonard, C. (1990) Mental retardation. In Emery, A. and Rimoin, D. (ed.), Principles and Practice of Medical Genetics. Edinburgh: Churchill Livingston, pp. 495-511.
2. Stevenson, R.E., Schwartz, C.E. and Schroer, R.J. (2000) X-Linked Mental Retardation. Oxford University Press, Oxford.
3. Chelly, J., and Mandel, J.L. (2001) Monogenic causes of X-linked mental retardation. Nat. Rev. Genet., 2, 669-680.
4. Carrie, A., Jun, L., Bienvenu, T., Vinet, M.C., McDonell, N., Convert, P., Zemni, R., Cardona, A., Van Buggenhout, G., Frints, S. et al. (1999) A new member of the IL-1 receptor family highly expressed in hippocampus and involved in X-linked mental retardation. Nat. Genet., 23, 25-31.
5. Greenfeder, S.A., Nunes, P., Kwee, L., Labow, M., Chizzonite, R.A. and Ju, G. (1995) Molecular cloning and characterization of a second subunit of the interleukin 1 receptor complex. J. Biol. Chem., 270, 13757-13765.
6. Huang, J., Gao, X., Li, S. and Cao, Z. (1997) Recruitment of IRAK to the interleukin 1 receptor complex requires interleukin 1 receptor accessory protein. Proc. Natl Acad. Sci. USA, 94, 12829-12832.
7. Born, T.L., Smith, D.E., Garka, K.E., Renshaw, B.R., Bertles, J.S. and Sims, J.E. (2000) Identification and characterization of two members of a novel class of the interleukin-1 receptor (IL-1R) family. Delineation of a new class of IL-1R-related proteins based on signaling. J. Biol. Chem., 275, 29946-29954.
8. Ferrante, M.I., Ghiani, M., Bulfone, A. and Franco, B. (2001) IL1RAPL2 maps to Xq22 and is specifically expressed in the central nervous system. Gene, 275, 217-221.
9. Dinarello, C.A. (1996) Biologic basis for interleukin-1 in disease. Blood, 87, 2095-2147.
10. Smith, D.E., Renshaw, B.R., Ketchem, R.R., Kubin, M., Garka, K.E. and Sims, J.E. (2000) Four new members expand the interleukin-1 superfamily. J. Biol. Chem., 275, 1169-1175.
11. 2+-binding proteins. Biochem. J., 353, 1-12.
12. Pongs, O., Lindemeier, J., Zhu, X.R., Theil, T., Engelkamp, D., Krah-Jentgens, I., Lambrecht, H.G., Koch, K.W., Schwemer, J., Rivosecchi, R. et al. (1993) Frequenin, a novel calcium-binding protein that modulates synaptic efficacy in the Drosophila nervous system. Neuron, 11, 15-28.
13. 2+ sensor 1, the mammalian homologue of frequenin, is expressed in chromaffin and PC12 cells and regulates neurosecretion from dense-core granules. J. Biol. Chem., 273, 22768-22772.
14. 2+ signal transduction J. Biol. Chem., 274, 30258-30265.
15. Underhill, D.M., Ozinsky, A., Hajjar, A.M., Stevens, A., Wilson, C.B., Bassetti, M. and Aderem, A. (1999) The Toll-like receptor 2 is recruited to macrophage phagosomes and discriminates between pathogens. Nature, 401, 811-815.
16. Muzio, M., Ni, J., Feng, P. and Dixit, V.M. (1997) IRAK (Pelle) family member IRAK-2 and MyD88 as proximal mediators of IL-1 signaling. Science, 278, 1612-1615.
17. Wesche, H., Henzel, W.J., Shillinglaw, W., Li, S. and Cao, Z. (1997) MyD88: an adaptor that recruits IRAK to the IL-1 receptor complex. Immunity, 7, 837-847.
18. Medzhitov, R., Preston-Hurlburt, P., Kopp, E., Stadlen, A., Chen, C., Ghosh, S. and Janeway, C.A. Jr (1998) MyD88 is an adaptor protein in the hToll/IL-1 receptor family signaling pathways. Mol. Cell, 2, 253-258.
19. Burns, K., Martinon, F., Esslinger, C., Pahl, H., Schneider, P., Bodmer, J.L., Di Marco, F., French, L. and Tschopp, J. (1998) MyD88, an adapter protein involved in interleukin-1 signaling. J. Biol. Chem., 273, 12203-12209.
20. Kopp, E.B. and Medzhitov, R. (1999) The Toll-receptor family and control of innate immunity. Curr. Opin. Immunol., 11, 13-18.
21. Xu, Y., Tao, X., Shen, B., Horng, T., Medzhitov, R., Manley, J.L. and Tong, L. (2000) Structural basis for signal transduction by the Toll/interleukin-1 receptor domains. Nature, 408, 111-115.
22. 2+ binding protein, frequenin is a nervous system-specific protein in mouse preferentially localized in neurites. Brain Res. Mol. Brain Res., 44, 73-82.
23. Martone, M.E., Edelmann, V.M., Ellisman, M.H. and Nef, P. (1999) Cellular and subcellular distribution of the calcium-binding protein NCS-1 in the central nervous system of the rat. Cell Tissue Res., 295, 395-407.
24. Scalettar, B.A., Rosa, P., Taverna, E., Francolini, M., Tsuboi, T., Terakawa, S., Koizumi, S., Roder, J. and Jeromin, A. (2002) Neuronal calcium sensor-1 binds to regulated secretory organelles and functions in basal and stimulated exocytosis in PC12 cells. J. Cell. Sci., 115, 2399-2412.
25. 2+ signal transduction. J. Biol. Chem., 277, 14227-14237.
26. Wick, P.F., Senter, R.A., Parsels, L.A., Uhler, M.D. and Holz, R.W. (1993) Transient transfection studies of secretion in bovine chromaffin cells and PC12 cells. Generation of kainate-sensitive chromaffin cells. J. Biol. Chem., 268, 10983-10989.
27. Gay, N.J. and Keith, F.J. (1991) Drosophila Toll and IL-1 receptor. Nature, 351, 355-356.
28. Schneider, D.S., Hudson, K.L., Lin, T.Y. and Anderson, K.V. (1991) Dominant and recessive mutations define functional domains of Toll, a transmembrane protein required for dorsal-ventral polarity in the Drosophila embryo. Genes Dev., 5, 797-807.
29. Imler, J.L. and Hoffmann, J.A. (2000) Toll and Toll-like proteins: an ancient family of receptors signaling infection. Rev. Immunogenet., 2, 294-304.
30. Ferrus, A., Llamazares, S., de la Pompa, J.L., Tanouye, M.A. and Pongs, O. (1990) Genetic analysis of the Shaker gene complex of Drosophila melanogaster. Genetics, 125, 383-398.
31. Rivosecchi, R., Pongs, O., Theil, T. and Mallart, A. (1994) Implication of frequenin in the facilitation of transmitter release in Drosophila. J. Physiol., 474, 223-232.
32. Nef, S., Fiumelli, H., de Castro, E., Raes, M.B. and Nef, P. (1995) Identification of neuronal calcium sensor (NCS-1) possibly involved in the regulation of receptor phosphorylation. J. Recept. Signal Transduct. Res., 15, 365-378.
33. Tsujimoto, T., Jeromin, A., Saitoh, N., Roder, J.C. and Takahashi, T. (2002) Neuronal calcium sensor 1 and activity-dependent facilitation of P/Q-type calcium currents at presynaptic nerve terminals. Science, 295, 2276-2279.
34. Kabbani, N., Negyessy, L., Lin, R., Goldman-Rakic, P. and Levenson, R. (2002) Interaction with neuronal calcium sensor NCS-1 mediates desensitization of the D2 dopamine receptor. J. Neurosci., 22, 8476-8486.
35. 2+ channels in bovine adrenal chromaffin cells. J. Biol. Chem., 275, 40082-40087.
36. Geppert, M. and Sudhof, T.C. (1998) RAB3 and synaptotagmin: the yin and yang of synaptic membrane fusion. A. Rev. Neurosci., 21, 75-95.
37. D'Adamo, P., Menegon, A., Lo Nigro, C., Grasso, M., Gulisano, M., Tamanini, F., Bienvenu, T., Gedeon, A.K., Oostra, B., Wu, S.K. et al. (1998) Mutations in GDI1 are responsible for X-linked non-specific mental retardation. Nat. Genet., 19, 134-139.
38. Bienvenu, T., des Portes, V., Saint Martin, A., McDonell, N., Billuart, P., Carrie, A., Vinet, M.C., Couvert, P., Toniolo, D., Ropers, H.H. et al. (1998) Non-specific X-linked semidominant mental retardation by mutations in a Rab GDP-dissociation inhibitor. Hum. Mol. Genet., 7, 1311-1315.
39. Ishizaki, H., Miyoshi, J., Kamiya, H., Togawa, A., Tanaka, M., Sasaki, T., Endo, K., Mizoguchi, A., Ozawa, S. and Takai, Y. (2000) Role of rab GDP dissociation inhibitor alpha in regulating plasticity of hippocampal neurotransmission. Proc. Natl Acad. Sci. USA, 97, 11587-11592.
40. Maniatis, T., Fritsch, E.F. and Sambrook J. (1982) Molecular Cloning: a Laboratory Manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
41. Bartel, P.L. and Fields, S. (1995) Analyzing protein-protein interactions using two-hybrid system. Meth. Enzymol., 254, 241-263.
42. Aspenstrom, P. and Olson, M.F. (1995) Yeast two-hybrid system to detect protein-protein interactions with Rho GTPases. Meth. Enzymol., 256, 228-241.
43. Corsaro, C.M. and Pearson, M.L. (1981) Enhancing the efficiency of DNA-mediated gene transfer in mammalian cells. Somatic Cell. Genet., 7, 603-616.
44. Laniece, P., Charon, Y., Cardona, A., Pinot, L., Maitrejean, S., Mastrippolito, R., Sandkamp, B. and Valentin, L. (1998) A new high resolution radioimager for the quantitative analysis of radiolabelled molecules in tissue section. J. Neurosci. Meth., 86, 1-5.
45. 125I-ligand receptor binding and pharmacological studies. Histochem. J., 28, 801-809.
46. Graham, M.E., Sudlow, A.W. and Burgoyne, R.D. (1997) Evidence against an acute inhibitory role of nSec-1 (munc-18) in late steps of regulated exocytosis in chromaffin and PC12 cells. J. Neurochem., 69, 2369-2377.