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Volumn 22, Issue 12, 2003, Pages 2924-2933

Drosophila polypyrimidine-tract binding protein (PTB) functions specifically in the male germline

Author keywords

Hephaestus; Male germline; PTB; Sex determination; Spermatogenesis

Indexed keywords

BINDING PROTEIN; MESSENGER RNA; POLYPYRIMIDINE TRACT BINDING PROTEIN; RIBONUCLEOPROTEIN; UNCLASSIFIED DRUG;

EID: 0038376134     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/cdg301     Document Type: Article
Times cited : (33)

References (73)
  • 1
    • 0037205229 scopus 로고    scopus 로고
    • Sex-specific deployment of FGF signaling in Drosophila recruits mesodermal cells into the male genital imaginal disc
    • Ahmad, S.M. and Baker, B.S. (2002) Sex-specific deployment of FGF signaling in Drosophila recruits mesodermal cells into the male genital imaginal disc. Cell, 109, 651-661.
    • (2002) Cell , vol.109 , pp. 651-661
    • Ahmad, S.M.1    Baker, B.S.2
  • 2
    • 13144268566 scopus 로고    scopus 로고
    • Sexual behaviour in Drosophila is irreversibly programmed during a critical period
    • Arthur, B.I., Jr, Jallon, J.M., Caflisch, B., Choffat, Y. and Nothiger, R. (1998) Sexual behaviour in Drosophila is irreversibly programmed during a critical period. Curr. Biol., 8, 1187-1190.
    • (1998) Curr. Biol. , vol.8 , pp. 1187-1190
    • Arthur B.I., Jr.1    Jallon, J.M.2    Caflisch, B.3    Choffat, Y.4    Nothiger, R.5
  • 3
    • 0003455528 scopus 로고
    • Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
    • Ashburner, M. (1989) Drosophila: A Laboratory Manual, Vol. 2. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
    • (1989) Drosophila: A Laboratory Manual , vol.2
    • Ashburner, M.1
  • 4
    • 0030777180 scopus 로고    scopus 로고
    • A neuron-specific splicing switch mediated by an array of pre-mRNA repressor sites: Evidence of a regulatory role for the polypyrimidine tract binding protein and a brain-specific PTB counterpart
    • Ashiya, M. and Grabowski, P.J. (1997) A neuron-specific splicing switch mediated by an array of pre-mRNA repressor sites: evidence of a regulatory role for the polypyrimidine tract binding protein and a brain-specific PTB counterpart. RNA, 3, 996-1015.
    • (1997) RNA , vol.3 , pp. 996-1015
    • Ashiya, M.1    Grabowski, P.J.2
  • 5
    • 0034235466 scopus 로고    scopus 로고
    • Picomavirus RNA translation: Roles for cellular proteins
    • Belsham, G.J. and Sonenberg, N. (2000) Picomavirus RNA translation: roles for cellular proteins. Trends Microbiol., 8, 330-335.
    • (2000) Trends Microbiol. , vol.8 , pp. 330-335
    • Belsham, G.J.1    Sonenberg, N.2
  • 6
    • 0034721644 scopus 로고    scopus 로고
    • Protein diversity from alternative splicing: A challenge for bioinformatics and post-genome biology
    • Black, D.L. (2000) Protein diversity from alternative splicing: a challenge for bioinformatics and post-genome biology. Cell, 103, 367-370.
    • (2000) Cell , vol.103 , pp. 367-370
    • Black, D.L.1
  • 7
    • 0022400587 scopus 로고
    • Tudor, a gene required for assembly of the germ plasm in Drosophila melanogaster
    • Boswell, R.E. and Mahowald, A.P. (1985) tudor, a gene required for assembly of the germ plasm in Drosophila melanogaster. Cell, 43, 97-104.
    • (1985) Cell , vol.43 , pp. 97-104
    • Boswell, R.E.1    Mahowald, A.P.2
  • 8
    • 0025784620 scopus 로고
    • Mutations in a newly identified Drosophila melanogaster gene, mago nashi, disrupt germ cell formation and result in the formation of mirror-image symmetrical double abdomen embryos
    • Boswell, R.E., Prout, M.E. and Steichen, J.C. (1991) Mutations in a newly identified Drosophila melanogaster gene, mago nashi, disrupt germ cell formation and result in the formation of mirror-image symmetrical double abdomen embryos. Development, 113, 373-384.
    • (1991) Development , vol.113 , pp. 373-384
    • Boswell, R.E.1    Prout, M.E.2    Steichen, J.C.3
  • 10
    • 0001468848 scopus 로고    scopus 로고
    • Splicing of precursors to mRNAs by the spliceosomes
    • Gesteland, R.F., Cech, T.R. and Atkins, J.F. (eds). Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
    • Burge, C.B., Tuschl, T. and Sharp, P.A. (1999) Splicing of precursors to mRNAs by the spliceosomes. In Gesteland, R.F., Cech, T.R. and Atkins, J.F. (eds), The RNA World, 2nd edn. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, pp. 525-560.
    • (1999) The RNA World, 2nd Edn. , pp. 525-560
    • Burge, C.B.1    Tuschl, T.2    Sharp, P.A.3
  • 11
    • 0027495444 scopus 로고
    • The regulation of sex determination and sexually dimorphic differentiation in Drosophila
    • Burtis, K.C. (1993) The regulation of sex determination and sexually dimorphic differentiation in Drosophila. Curr. Opin. Cell Biol., 5, 1006-1014.
    • (1993) Curr. Opin. Cell Biol. , vol.5 , pp. 1006-1014
    • Burtis, K.C.1
  • 12
    • 0034021646 scopus 로고    scopus 로고
    • A new family of adenylyl cyclase genes in the male germline of Drosophila melanogaster
    • Cann, M.J., Chung, E. and Levin, L.R. (2000) A new family of adenylyl cyclase genes in the male germline of Drosophila melanogaster. Dev. Genes Evol., 210, 200-206.
    • (2000) Dev. Genes Evol. , vol.210 , pp. 200-206
    • Cann, M.J.1    Chung, E.2    Levin, L.R.3
  • 13
    • 0027444586 scopus 로고
    • Toward a molecular genetic analysis of spermatogenesis in Drosophila melanogaster: Characterization of male-sterile mutants generated by single P element mutagenesis
    • Castrillon, D.H., Gonczy, P., Alexander, S., Rawson, R., Eberhart, C.G., Viswanathan, S., DiNardo, S. and Wasserman, S.A. (1993) Toward a molecular genetic analysis of spermatogenesis in Drosophila melanogaster: characterization of male-sterile mutants generated by single P element mutagenesis. Genetics, 135, 489-505.
    • (1993) Genetics , vol.135 , pp. 489-505
    • Castrillon, D.H.1    Gonczy, P.2    Alexander, S.3    Rawson, R.4    Eberhart, C.G.5    Viswanathan, S.6    DiNardo, S.7    Wasserman, S.A.8
  • 14
    • 0030872401 scopus 로고    scopus 로고
    • The polypyrimidine tract binding protein binds upstream of neural cell-specific c-src exon N1 to repress the splicing of the intron downstream
    • Chan, R.C. and Black, D.L. (1997) The polypyrimidine tract binding protein binds upstream of neural cell-specific c-src exon N1 to repress the splicing of the intron downstream. Mol. Cell. Biol., 17, 4667-4676.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 4667-4676
    • Chan, R.C.1    Black, D.L.2
  • 15
    • 0030300044 scopus 로고    scopus 로고
    • Vive la difference: Males vs females in flies vs worms
    • Cline, T.W. and Meyer, B.J. (1996) Vive la difference: males vs females in flies vs worms. Annu. Rev. Genet., 30, 637-702.
    • (1996) Annu. Rev. Genet. , vol.30 , pp. 637-702
    • Cline, T.W.1    Meyer, B.J.2
  • 16
    • 0036882278 scopus 로고    scopus 로고
    • Hephaestus encodes a polypyrimidine tract binding protein that regulates Notch signalling during wing development in Drosophila melanogaster
    • Dansereau, D.A., Lunke, M.D., Finkielsztein, A., Russell, M.A. and Brook, W.J. (2002) hephaestus encodes a polypyrimidine tract binding protein that regulates Notch signalling during wing development in Drosophila melanogaster. Development, 129, 5553-5566.
    • (2002) Development , vol.129 , pp. 5553-5566
    • Dansereau, D.A.1    Lunke, M.D.2    Finkielsztein, A.3    Russell, M.A.4    Brook, W.J.5
  • 17
    • 0036169704 scopus 로고    scopus 로고
    • Lineage-specific expression of polypyrimidine tract binding protein (PTB) in Drosophila embryos
    • Davis, M.B., Sun, W. and Standiford, D.M. (2002) Lineage-specific expression of polypyrimidine tract binding protein (PTB) in Drosophila embryos. Mech. Dev., 111, 143-147.
    • (2002) Mech. Dev. , vol.111 , pp. 143-147
    • Davis, M.B.1    Sun, W.2    Standiford, D.M.3
  • 19
    • 0031800970 scopus 로고    scopus 로고
    • Genetic dissection of sperm individualization in Drosophila melanogaster
    • Fabrizio, J.J., Hime, G., Lemmon, S.K. and Bazinet, C. (1998) Genetic dissection of sperm individualization in Drosophila melanogaster. Development, 125, 1833-1843.
    • (1998) Development , vol.125 , pp. 1833-1843
    • Fabrizio, J.J.1    Hime, G.2    Lemmon, S.K.3    Bazinet, C.4
  • 20
    • 0001926223 scopus 로고
    • Spermatogenesis
    • Bate, M. and Arias, A.M. (eds). Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
    • Fuller, M.T. (1993) Spermatogenesis. In Bate, M. and Arias, A.M. (eds), The Development of Drosophila melanogaster, Vol. I. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, pp. 71-147.
    • (1993) The Development of Drosophila Melanogaster , vol.1 , pp. 71-147
    • Fuller, M.T.1
  • 21
    • 0026660025 scopus 로고
    • hnRNP I, the polypyrimidine tract-binding protein: Distinct nuclear localization and association with hnRNAs
    • Ghetti, A., Pinol-Roma, S., Michael, W.M., Morandi, C. and Dreyfuss, G. (1992) hnRNP I, the polypyrimidine tract-binding protein: distinct nuclear localization and association with hnRNAs. Nucleic Acids Res., 20, 3671-3678.
    • (1992) Nucleic Acids Res. , vol.20 , pp. 3671-3678
    • Ghetti, A.1    Pinol-Roma, S.2    Michael, W.M.3    Morandi, C.4    Dreyfuss, G.5
  • 22
    • 0025893215 scopus 로고
    • Characterization of cDNAs encoding the polypyrimidine tract-binding protein
    • Gil, A., Sharp, P.A., Jamison, S.F. and Garcia-Blanco, M.A. (1991) Characterization of cDNAs encoding the polypyrimidine tract-binding protein. Genes Dev., 5, 1224-1236.
    • (1991) Genes Dev. , vol.5 , pp. 1224-1236
    • Gil, A.1    Sharp, P.A.2    Jamison, S.F.3    Garcia-Blanco, M.A.4
  • 23
    • 0031985529 scopus 로고    scopus 로고
    • Role of an inhibitory pyrimidine element and polypyrimidine tract binding protein in repression of a regulated α-tropomyosin exon
    • Gooding, C., Roberts, G.C. and Smith, C.W. (1998) Role of an inhibitory pyrimidine element and polypyrimidine tract binding protein in repression of a regulated α-tropomyosin exon. RNA, 4, 85-100.
    • (1998) RNA , vol.4 , pp. 85-100
    • Gooding, C.1    Roberts, G.C.2    Smith, C.W.3
  • 24
    • 0035252410 scopus 로고    scopus 로고
    • Alternative splicing: Increasing diversity in the proteomic world
    • Graveley, B.R. (2001) Alternative splicing: increasing diversity in the proteomic world. Trends Genet., 17, 100-107.
    • (2001) Trends Genet. , vol.17 , pp. 100-107
    • Graveley, B.R.1
  • 25
    • 0025787954 scopus 로고
    • Biochemical mechanisms of constitutive and regulated pre-mRNA splicing
    • Green, M.R. (1991) Biochemical mechanisms of constitutive and regulated pre-mRNA splicing. Annu. Rev. Cell Biol., 7, 559-599.
    • (1991) Annu. Rev. Cell Biol. , vol.7 , pp. 559-599
    • Green, M.R.1
  • 26
    • 0032079066 scopus 로고    scopus 로고
    • Drosophila, female gonadal cells repress male-specific gene expression in XX germ cells
    • Heller, A. and Steinmann-Zwicky, M. (1998) In Drosophila, female gonadal cells repress male-specific gene expression in XX germ cells. Mech. Dev., 73, 203-209.
    • (1998) Mech. Dev. , vol.73 , pp. 203-209
    • Heller, A.1    Steinmann-Zwicky, M.2
  • 27
    • 0035211878 scopus 로고    scopus 로고
    • Cell-autonomous and somatic signals control sex-specific gene expression in XY germ cells of Drosophila
    • Janzer, B. and Steinmann-Zwicky, M. (2001) Cell-autonomous and somatic signals control sex-specific gene expression in XY germ cells of Drosophila. Mech. Dev., 100, 3-13.
    • (2001) Mech. Dev. , vol.100 , pp. 3-13
    • Janzer, B.1    Steinmann-Zwicky, M.2
  • 28
    • 0029397360 scopus 로고
    • Direct evidence that polypyrimidine tract binding protein (PTB) is essential for internal initiation of translation of encephalomyocarditis virus RNA
    • Kaminski, A., Hunt, S.L., Patton, J.G. and Jackson, R.J. (1995) Direct evidence that polypyrimidine tract binding protein (PTB) is essential for internal initiation of translation of encephalomyocarditis virus RNA. RNA, 1, 924-938.
    • (1995) RNA , vol.1 , pp. 924-938
    • Kaminski, A.1    Hunt, S.L.2    Patton, J.G.3    Jackson, R.J.4
  • 29
    • 0026527993 scopus 로고
    • The primary sex determination signal of Drosophila acts at the level of transcription
    • Keyes, L.N., Cline, T.W. and Schedl, P. (1992) The primary sex determination signal of Drosophila acts at the level of transcription. Cell, 68, 933-943.
    • (1992) Cell , vol.68 , pp. 933-943
    • Keyes, L.N.1    Cline, T.W.2    Schedl, P.3
  • 30
    • 0033153348 scopus 로고    scopus 로고
    • hnRNP complexes: Composition, structure, and function
    • Krecic, A.M. and Swanson, M.S. (1999) hnRNP complexes: composition, structure, and function. Curr. Opin. Cell Biol., 11, 363-371.
    • (1999) Curr. Opin. Cell Biol. , vol.11 , pp. 363-371
    • Krecic, A.M.1    Swanson, M.S.2
  • 32
    • 0029295295 scopus 로고
    • Regulation of alternative 3′ splice site selection by constitutive splicing factors
    • Lin, C.H. and Patton, J.G. (1995) Regulation of alternative 3′ splice site selection by constitutive splicing factors. RNA, 1, 234-245.
    • (1995) RNA , vol.1 , pp. 234-245
    • Lin, C.H.1    Patton, J.G.2
  • 33
    • 0032435862 scopus 로고    scopus 로고
    • Alternative splicing of pre-mRNA: Developmental consequences and mechanisms of regulation
    • Lopez, A.J. (1998) Alternative splicing of pre-mRNA: developmental consequences and mechanisms of regulation. Annu. Rev. Genet., 32, 279-305.
    • (1998) Annu. Rev. Genet. , vol.32 , pp. 279-305
    • Lopez, A.J.1
  • 35
    • 0030067593 scopus 로고    scopus 로고
    • An intron enhancer recognized by splicing factors activates polyadenylation
    • Lou, H., Gagel, R.F. and Berget, S.M. (1996) An intron enhancer recognized by splicing factors activates polyadenylation. Genes Dev., 10, 208-219.
    • (1996) Genes Dev. , vol.10 , pp. 208-219
    • Lou, H.1    Gagel, R.F.2    Berget, S.M.3
  • 36
    • 0032938851 scopus 로고    scopus 로고
    • Polypyrimidine tract-binding protein positively regulates inclusion of an alternative 3′-terminal exon
    • Lou, H., Helfman, D.M., Gagel, R.F. and Berget, S.M. (1999) Polypyrimidine tract-binding protein positively regulates inclusion of an alternative 3′-terminal exon. Mol. Cell. Biol., 19, 78-85.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 78-85
    • Lou, H.1    Helfman, D.M.2    Gagel, R.F.3    Berget, S.M.4
  • 37
    • 0028711927 scopus 로고
    • Sex determination of germ cells in Drosophila
    • Mahowald, A.P. and Wei, G. (1994) Sex determination of germ cells in Drosophila. Ciba Found. Symp., 182, 193-202.
    • (1994) Ciba Found. Symp. , vol.182 , pp. 193-202
    • Mahowald, A.P.1    Wei, G.2
  • 38
    • 0032566586 scopus 로고    scopus 로고
    • The evolutionary dynamics of sex determination
    • Marin, I. and Baker, B.S. (1998) The evolutionary dynamics of sex determination. Science, 281, 1990-1994.
    • (1998) Science , vol.281 , pp. 1990-1994
    • Marin, I.1    Baker, B.S.2
  • 39
    • 0018145178 scopus 로고
    • Is sex determination in germ line and soma controlled by separate genetic mechanisms?
    • Marsh, J.L. and Wieschaus, E. (1978) Is sex determination in germ line and soma controlled by separate genetic mechanisms? Nature, 272, 249-251.
    • (1978) Nature , vol.272 , pp. 249-251
    • Marsh, J.L.1    Wieschaus, E.2
  • 40
    • 0023921858 scopus 로고
    • Ectopic expression of the female transformer gene product leads to female differentiation of chromosomally male Drosophila
    • McKeown, M., Belote, J.M. and Boggs, R.T. (1988) Ectopic expression of the female transformer gene product leads to female differentiation of chromosomally male Drosophila. Cell, 53, 887-895.
    • (1988) Cell , vol.53 , pp. 887-895
    • McKeown, M.1    Belote, J.M.2    Boggs, R.T.3
  • 41
    • 0342723790 scopus 로고    scopus 로고
    • Frequent alternative splicing of human genes
    • Mironov, A.A., Fickett, J.W. and Gelfand, M.S. (1999) Frequent alternative splicing of human genes. Genome Res., 9, 1288-1293.
    • (1999) Genome Res. , vol.9 , pp. 1288-1293
    • Mironov, A.A.1    Fickett, J.W.2    Gelfand, M.S.3
  • 42
    • 0001877802 scopus 로고
    • Splicing of precursors to mRNA by the spliceosome
    • Gesteland, R.F. and Atkins, J.F. (eds). Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
    • Moore, M.J., Query, C.C. and Sharp, P.A. (1993) Splicing of precursors to mRNA by the spliceosome. In Gesteland, R.F. and Atkins, J.F. (eds), The RNA World. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, pp. 303-357.
    • (1993) The RNA World , pp. 303-357
    • Moore, M.J.1    Query, C.C.2    Sharp, P.A.3
  • 43
    • 0026480757 scopus 로고
    • Polypyrimidine tract binding protein interacts with sequences involved in alternative splicing of β-tropomyosin pre-mRNA
    • Mulligan, G.J., Guo, W., Wormsley, S. and Helfman, D.M. (1992) Polypyrimidine tract binding protein interacts with sequences involved in alternative splicing of β-tropomyosin pre-mRNA. J. Biol. Chem., 267, 25480-25487.
    • (1992) J. Biol. Chem. , vol.267 , pp. 25480-25487
    • Mulligan, G.J.1    Guo, W.2    Wormsley, S.3    Helfman, D.M.4
  • 44
    • 0025189682 scopus 로고
    • Regulation of sex-specific RNA splicing at the Drosophila doublesex gene: Cis-acting mutations in exon sequences alter sex-specific RNA splicing patterns
    • Nagoshi, R.N. and Baker, B.S. (1990) Regulation of sex-specific RNA splicing at the Drosophila doublesex gene: cis-acting mutations in exon sequences alter sex-specific RNA splicing patterns. Genes Dev., 4, 89-97.
    • (1990) Genes Dev. , vol.4 , pp. 89-97
    • Nagoshi, R.N.1    Baker, B.S.2
  • 45
    • 0024294339 scopus 로고
    • The control of alternative splicing at genes regulating sexual differentiation in D.melanogaster
    • Nagoshi, R.N., McKeown, M., Burtis, K.C., Belote, J.M. and Baker, B.S. (1988) The control of alternative splicing at genes regulating sexual differentiation in D.melanogaster. Cell, 53, 229-236.
    • (1988) Cell , vol.53 , pp. 229-236
    • Nagoshi, R.N.1    McKeown, M.2    Burtis, K.C.3    Belote, J.M.4    Baker, B.S.5
  • 46
    • 0034649685 scopus 로고    scopus 로고
    • The case for an RNA enzyme
    • Nilsen, T.W. (2000) The case for an RNA enzyme. Nature, 408, 782-783.
    • (2000) Nature , vol.408 , pp. 782-783
    • Nilsen, T.W.1
  • 47
    • 0036161499 scopus 로고    scopus 로고
    • The spliceosome: No assembly required?
    • Nilsen, T.W. (2002) The spliceosome: no assembly required? Mol. Cell, 9, 8-9.
    • (2002) Mol. Cell , vol.9 , pp. 8-9
    • Nilsen, T.W.1
  • 48
    • 0025856790 scopus 로고
    • Characterization and molecular cloning of polypyrimidine tract-binding protein: A component of a complex necessary for pre-mRNA splicing
    • Patton, J.G., Mayer, S.A., Tempst, P. and Nadal-Ginard, B. (1991) Characterization and molecular cloning of polypyrimidine tract-binding protein: a component of a complex necessary for pre-mRNA splicing. Genes Dev., 5, 1237-1251.
    • (1991) Genes Dev. , vol.5 , pp. 1237-1251
    • Patton, J.G.1    Mayer, S.A.2    Tempst, P.3    Nadal-Ginard, B.4
  • 49
    • 0034612372 scopus 로고    scopus 로고
    • A brain-enriched polypyrimidine tract-binding protein antagonizes the ability of Nova to regulate neuron-specific alternative splicing
    • Polydorides, A.D., Okano, H.J., Yang, Y.Y., Stefani, G. and Darnell, R.B. (2000) A brain-enriched polypyrimidine tract-binding protein antagonizes the ability of Nova to regulate neuron-specific alternative splicing. Proc. Natl Acad. Sci. USA, 97, 6350-6355.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 6350-6355
    • Polydorides, A.D.1    Okano, H.J.2    Yang, Y.Y.3    Stefani, G.4    Darnell, R.B.5
  • 51
    • 0034668046 scopus 로고    scopus 로고
    • Dmrt1, a gene related to worm and fly sexual regulators, is required for mammalian testis differentiation
    • Raymond, C.S., Murphy, M.W., O'Sullivan, M.G., Bardwell, V.J. and Zarkower, D. (2000) Dmrt1, a gene related to worm and fly sexual regulators, is required for mammalian testis differentiation. Genes Dev., 14, 2587-2595.
    • (2000) Genes Dev. , vol.14 , pp. 2587-2595
    • Raymond, C.S.1    Murphy, M.W.2    O'Sullivan, M.G.3    Bardwell, V.J.4    Zarkower, D.5
  • 52
    • 0034069505 scopus 로고    scopus 로고
    • Mechanisms of fidelity in pre-mRNA splicing
    • Reed, R. (2000) Mechanisms of fidelity in pre-mRNA splicing. Curr. Opin. Cell Biol., 12, 340-345.
    • (2000) Curr. Opin. Cell Biol. , vol.12 , pp. 340-345
    • Reed, R.1
  • 54
    • 0020012431 scopus 로고
    • Autosomal mutations that interfere with sex determination in somatic cells of Drosophila have no direct effect on the germline
    • Schupbach, T. (1982) Autosomal mutations that interfere with sex determination in somatic cells of Drosophila have no direct effect on the germline. Dev. Biol., 89, 117-127.
    • (1982) Dev. Biol. , vol.89 , pp. 117-127
    • Schupbach, T.1
  • 55
    • 0342470996 scopus 로고    scopus 로고
    • Structure, function and evolution of sex-determining systems in Dipteran insects
    • Schutt, C. and Nothiger, R. (2000) Structure, function and evolution of sex-determining systems in Dipteran insects. Development, 127, 667-677.
    • (2000) Development , vol.127 , pp. 667-677
    • Schutt, C.1    Nothiger, R.2
  • 56
    • 0036176773 scopus 로고    scopus 로고
    • RNA-protein interactions that regulate pre-mRNA splicing
    • Singh, R. (2002) RNA-protein interactions that regulate pre-mRNA splicing. Gene Expr., 10, 79-92.
    • (2002) Gene Expr. , vol.10 , pp. 79-92
    • Singh, R.1
  • 57
    • 0029055472 scopus 로고
    • Distinct binding specificities and functions of higher eukaryotic polypyrimidine tract-binding proteins
    • Singh, R., Valcarcel, J. and Green, M.R. (1995) Distinct binding specificities and functions of higher eukaryotic polypyrimidine tract-binding proteins. Science, 268, 1173-1176.
    • (1995) Science , vol.268 , pp. 1173-1176
    • Singh, R.1    Valcarcel, J.2    Green, M.R.3
  • 58
    • 0034256020 scopus 로고    scopus 로고
    • Alternative pre-mRNA splicing: The logic of combinatorial control
    • Smith, C.W. and Valcarcel, J. (2000) Alternative pre-mRNA splicing: the logic of combinatorial control. Trends Biochem. Sci., 25, 381-388.
    • (2000) Trends Biochem. Sci. , vol.25 , pp. 381-388
    • Smith, C.W.1    Valcarcel, J.2
  • 59
    • 0032883802 scopus 로고    scopus 로고
    • The Berkeley Drosophila Genome Project gene disruption project: Single P-element insertions mutating 25% of vital Drosophila genes
    • Spradling, A.C., Stern, D., Beaton, A., Rhem, E.J., Laverty, T., Mozden, N., Misra, S. and Rubin, G.M. (1999) The Berkeley Drosophila Genome Project gene disruption project: single P-element insertions mutating 25% of vital Drosophila genes. Genetics, 153, 135-177.
    • (1999) Genetics , vol.153 , pp. 135-177
    • Spradling, A.C.1    Stern, D.2    Beaton, A.3    Rhem, E.J.4    Laverty, T.5    Mozden, N.6    Misra, S.7    Rubin, G.M.8
  • 60
    • 0032489021 scopus 로고    scopus 로고
    • Mechanical devices of the spliceosome: Motors, clocks, springs, and things
    • Staley, J.P. and Guthrie, C. (1998) Mechanical devices of the spliceosome: motors, clocks, springs, and things. Cell, 92, 315-326.
    • (1998) Cell , vol.92 , pp. 315-326
    • Staley, J.P.1    Guthrie, C.2
  • 61
    • 0026911109 scopus 로고
    • How do germ cells choose their sex? Drosophila as a paradigm
    • Steinmann-Zwicky, M. (1992) How do germ cells choose their sex? Drosophila as a paradigm. BioEssays, 14, 513-518.
    • (1992) BioEssays , vol.14 , pp. 513-518
    • Steinmann-Zwicky, M.1
  • 62
    • 0028265060 scopus 로고
    • Sex determination of the Drosophila germ line: Tra and dsx control somatic inductive signals
    • Steinmann-Zwicky, M. (1994) Sex determination of the Drosophila germ line: tra and dsx control somatic inductive signals. Development, 120, 707-716.
    • (1994) Development , vol.120 , pp. 707-716
    • Steinmann-Zwicky, M.1
  • 63
    • 0024581021 scopus 로고
    • Cell-autonomous and inductive signals can determine the sex of the germ line of Drosophila by regulating the gene Sx1
    • Steinmann-Zwicky, M., Schmid, H. and Nothiger, R. (1989) Cell-autonomous and inductive signals can determine the sex of the germ line of Drosophila by regulating the gene Sx1. Cell, 57, 157-166.
    • (1989) Cell , vol.57 , pp. 157-166
    • Steinmann-Zwicky, M.1    Schmid, H.2    Nothiger, R.3
  • 64
    • 0036005844 scopus 로고    scopus 로고
    • mgm1, the earliest sex-specific germline marker in Drosophila, reflects expression of the gene esg in male stem cells
    • Streit, A., Bernasconi, L., Sergeev, P., Cruz, A. and Steinmann-Zwicky, M. (2002) mgm1, the earliest sex-specific germline marker in Drosophila, reflects expression of the gene esg in male stem cells. Int. J. Dev. Biol., 46, 159-166.
    • (2002) Int. J. Dev. Biol. , vol.46 , pp. 159-166
    • Streit, A.1    Bernasconi, L.2    Sergeev, P.3    Cruz, A.4    Steinmann-Zwicky, M.5
  • 65
    • 0000182225 scopus 로고
    • Methods
    • Wood, W.W. (ed.). Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
    • Sulston, J. and Hodgkin, J. (1988) Methods. In Wood, W.W. (ed.), The Nematode Caenorhabditis elegans. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, pp. 587-606.
    • (1988) The Nematode Caenorhabditis Elegans , pp. 587-606
    • Sulston, J.1    Hodgkin, J.2
  • 66
    • 0031282306 scopus 로고    scopus 로고
    • Post-transcriptional regulation: The dawn of PTB
    • Valcarcel, J. and Gebauer, F. (1997) Post-transcriptional regulation: the dawn of PTB. Curr. Biol., 7, R705-R708.
    • (1997) Curr. Biol. , vol.7
    • Valcarcel, J.1    Gebauer, F.2
  • 68
    • 0031860374 scopus 로고    scopus 로고
    • RNA recognition by RNP proteins during RNA processing
    • Varani, G. and Nagai, K. (1998) RNA recognition by RNP proteins during RNA processing. Annu. Rev. Biophys. Biomol. Struct., 27, 407-445.
    • (1998) Annu. Rev. Biophys. Biomol. Struct. , vol.27 , pp. 407-445
    • Varani, G.1    Nagai, K.2
  • 69
    • 0035038207 scopus 로고    scopus 로고
    • Polypyrimidine tract binding protein antagonizes exon definition
    • Wagner, E.J. and Garcia-Blanco, M.A. (2001) Polypyrimidine tract binding protein antagonizes exon definition. Mol. Cell. Biol., 21, 3281-3288.
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 3281-3288
    • Wagner, E.J.1    Garcia-Blanco, M.A.2
  • 70
    • 0036810248 scopus 로고    scopus 로고
    • RNAi-mediated PTB depletion leads to enhanced exon definition
    • Wagner, E.J. and Garcia-Blanco, M.A. (2002) RNAi-mediated PTB depletion leads to enhanced exon definition. Mol. Cell, 10, 943-949.
    • (2002) Mol. Cell , vol.10 , pp. 943-949
    • Wagner, E.J.1    Garcia-Blanco, M.A.2
  • 71
    • 0033624528 scopus 로고    scopus 로고
    • Sex determination in the Drosophila germline is dictated by the sexual identity of the surrounding soma
    • Waterbury, J.A., Horabin, J.I., Bopp, D. and Schedl, P. (2000) Sex determination in the Drosophila germline is dictated by the sexual identity of the surrounding soma. Genetics, 155, 1741-1756.
    • (2000) Genetics , vol.155 , pp. 1741-1756
    • Waterbury, J.A.1    Horabin, J.I.2    Bopp, D.3    Schedl, P.4
  • 72
    • 0343907206 scopus 로고    scopus 로고
    • Protein functions in pre-mRNA splicing
    • Will, C.L. and Luhrmann, R. (1997) Protein functions in pre-mRNA splicing. Curr. Opin. Cell Biol., 9, 320-328.
    • (1997) Curr. Opin. Cell Biol. , vol.9 , pp. 320-328
    • Will, C.L.1    Luhrmann, R.2
  • 73
    • 0036360295 scopus 로고    scopus 로고
    • Invertebrates may not be so different after all
    • Zarkower, D. (2002) Invertebrates may not be so different after all. Novartis Found. Symp., 244, 115-126.
    • (2002) Novartis Found. Symp. , vol.244 , pp. 115-126
    • Zarkower, D.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.