Protonation and reactivity towards carbon dioxide of the mononuclear tetrahedral zinc and cobalt hydroxide complexes, [TpBut,Me]ZnOH and [TpBut,Me]CoOH: Comparison of the reactivity of the metal hydroxide function in synthetic analogues of carbonic anhydrase

Journal of the American Chemical Society

Volumn 125, Issue 20, 2003, Pages 6189-6199

  Bergquist, Catherine ^a   Fillebeen, Tauqir ^a   Morlok, Melissa M ^a   Parkin, Gerard ^a  

^a Columbia University ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTONATION;

CARBON DIOXIDE; CATALYSTS; COBALT COMPOUNDS; HYDROGEN BONDS; MOLECULAR STRUCTURE;

ZINC COMPOUNDS;

CARBON DIOXIDE; CARBONATE DEHYDRATASE; COBALT COMPLEX; COBALT HYDROXIDE; HYDROXIDE; UNCLASSIFIED DRUG; ZINC COMPLEX; ZINC HYDROXIDE;

ARTICLE; COMPLEX FORMATION; MOLECULAR INTERACTION; PROTON TRANSPORT; SYNTHESIS; X RAY DIFFRACTION;

BIOMIMETIC MATERIALS; CARBON DIOXIDE; CARBONIC ANHYDRASES; COBALT; HYDROXIDES; MODELS, MOLECULAR; MOLECULAR STRUCTURE; ORGANOMETALLIC COMPOUNDS; PROTONS; SPECTROPHOTOMETRY, INFRARED; THERMODYNAMICS; X-RAY DIFFRACTION; ZINC COMPOUNDS;

EID: 0038288708     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja034711j     Document Type: Article

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80. +, although specific details of the experiment to determine this value were not provided. See ref 6b.
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82. For other calculations on zinc and cobalt species with relevance to carbonic anhydrase, see: (a) Garmer, D. R.; Krauss, M. J. Am. Chem. Soc. 1992, 114, 6487-6493. (b) Garmer, D. R.; Krauss, M. Int. J. Quantum Chem. 1992, 42, 1469-1477. (c) Sola, M.; Mestres, J.; Duran, M.; Carbo, R. J. Chem. Inf. Comput. Sci. 1994, 34, 1047-1053. (d) Vedani, A.; Huhta, D. W. J. Am. Chem. Soc. 1990, 112, 4759-4767.
83. For other calculations on zinc and cobalt species with relevance to carbonic anhydrase, see: (a) Garmer, D. R.; Krauss, M. J. Am. Chem. Soc. 1992, 114, 6487-6493. (b) Garmer, D. R.; Krauss, M. Int. J. Quantum Chem. 1992, 42, 1469-1477. (c) Sola, M.; Mestres, J.; Duran, M.; Carbo, R. J. Chem. Inf. Comput. Sci. 1994, 34, 1047-1053. (d) Vedani, A.; Huhta, D. W. J. Am. Chem. Soc. 1990, 112, 4759-4767.
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