Synthesis of (R)-2-methyl-4-deoxy and (R)-2-methyl-4,5-dideoxy analogues of 6-phosphogluconate as potential inhibitors of 6-phosphogluconate dehydrogenase

Organic and Biomolecular Chemistry

Volumn 1, Issue 3, 2003, Pages 552-559

  Dardonville, Christophe ^a   Gilbert, Ian H ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CRYSTALLOGRAPHY; ENZYME INHIBITION; REACTION KINETICS; SYNTHESIS (CHEMICAL);

METHYLDEOXY; METHYLDIDEOXY; PHOSPHOGLUCONATE; PHOSPHOGLUCONATE DEHYDROGENASE;

ORGANIC COMPOUNDS;

6 PHOSPHOGLUCONIC ACID; 6-PHOSPHOGLUCONATE; DEOXYSUGAR; ENZYME INHIBITOR; GLUCONIC ACID; PHOSPHOGLUCONATE DEHYDROGENASE;

ANIMAL; ARTICLE; CHEMISTRY; DRUG ANTAGONISM; ENZYMOLOGY; METABOLISM; STEREOISOMERISM; SYNTHESIS; TRYPANOSOMA BRUCEI;

ANIMALS; DEOXY SUGARS; ENZYME INHIBITORS; GLUCONATES; PHOSPHOGLUCONATE DEHYDROGENASE; STEREOISOMERISM; TRYPANOSOMA BRUCEI BRUCEI;

EID: 0038151107     PISSN: 14770520     EISSN: None     Source Type: Journal    
DOI: 10.1039/b210606j     Document Type: Article

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