An electron microscopic and biochemical study of the effects of propranolol on the glycogen autophagy in newborn rat hepatocytes

Histology and Histopathology

Volumn 18, Issue 3, 2003, Pages 811-818

  Kotoulas, O B ^a   Kalamidas, Stefanos A ^a   Miles, P ^b   Hann, A C ^b  

^a UNIVERSITY OF IOANNINA   (Greece)

^b CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

Acid glucosidase; Acid mannose 6 phosphatase; Autophagy; Glycogen; Propranolol

Indexed keywords

ADENOSINE TRIPHOSPHATASE (CALCIUM); ALPHA GLUCOSIDASE; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; FORMYLMETHIONYLLEUCYLPHENYLALANINE; GLUCOSIDASE; GLYCOGEN; MANNOSE 6 PHOSPHATE; PROPRANOLOL;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; AUTOPHAGY; BIOCHEMISTRY; CALCIUM TRANSPORT; CELL STRUCTURE; CELL VACUOLE; CHEMICAL ANALYSIS; CONTROLLED STUDY; DRUG EFFECT; ELECTRON MICROSCOPY; ENZYME ACTIVITY; ENZYME INHIBITION; GLYCOGEN LIVER LEVEL; GLYCOGEN METABOLISM; LIVER CELL; LIVER LYSOSOME; NEWBORN; NONHUMAN; PROTEIN HYDROLYSIS; RAT;

ADENOSINE TRIPHOSPHATASES; ADRENERGIC BETA-ANTAGONISTS; ALPHA-GLUCOSIDASES; ANIMALS; ANIMALS, NEWBORN; AUTOPHAGY; BIOCHEMISTRY; CELLS, CULTURED; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; GLYCOGEN; HEPATOCYTES; IMMUNOHISTOCHEMISTRY; LIVER; MICROSCOPY, ELECTRON; PHOSPHORIC MONOESTER HYDROLASES; PROPRANOLOL; RATS; TIME FACTORS;

ANIMALIA;

EID: 0038127136     PISSN: 02133911     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (75)

1. Ajzannay A. and Mithieux G. (1996). Glucose 6-phosphate and mannose 6-phosphate are equally and more actively hydrolyzed by glucose 6-phosphatase during hysteretic transition within intact microsomal membrane than after detergent treatment. Arch. Biochem. Biophys. 326, 238-242.
2. Ajzannay A., Minassian C., Riou J.P. and Mithieux G. (1993). Glucose-6-phosphate phosphohydrolase of detergent-treated liver microscomal membranes exhibits a specific kinetic behaviour towards glucose 6-phosphate. Eur. J. Biochem. 212, 335-338.
3. +-ATPase in guinea pig heart preparation. Can. J. Physiol. Pharmacol. 79, 8-12.
4. Arion W.J. and Nordlie R.C. (1964). Liver microsomal glucose 6-phosphatase, inorganic pyrophosphatase and pyrophosphate-glucose phosphotransferase. J. Biol. Chem. 239, 2752-2757.
5. Bresciani R. and VonFigura K. (1996). Dephosphorylation of the mannose 6-phosphate recognition marker is localized in late compartments of the endocytic routes. Identification of purple acid phosphatase (uteroferrin) as the candidate phosphatase. Eur. J. Biochem. 238, 669-674.
6. Caroni P. and Carafoli E. (1981). Regulation of Ca2+-pumping ATPase of heart sarcolemma by a phosphorylation-dephosphorylation process. J. Biol. Chem. 256, 9371-9373.
7. Cheng A., Dube N., Gu F. and Tremblay M.I. (2002). Coordinated action of protein tyrosine phosphatases in insulin signal transduction. Eur. J. Biochem. 269, 1050-1059.
8. Dash R., Kadambi V.J., Schmidt A.G., Tepe N.M., Biniakiewicz D., Gerst M.J., Canning A.M., Abraham W.T., Hoit B.D., Liggett S.B., Lorenz J.N. and Kranias E.G. (2001). Interactions between phospholamban and beta-adrenergic drive may lead to cardiomyopathy and early mortality. Circulation 103, 889-896.
9. DeCamilli P., Moretti M., Donini S.D., Walter U. and Lohmann S.M. (1986). Heterogeneous distribution of cAMP receptor protein RII in the nervous system: Evidence for its intracellular accumulation on microtubules, microtubule-organizing centers, and in the area of the Golgi complex. J. Cell Biol. 103, 189-203.
10. DeDuve C. and Wattiaux R. (1966). Functions of lysosomes. Annu. Rev. Physiol. 28, 435-492.
11. Dell'Acqua M.L. and Scott J.D. (1997). Protein kinase A anchoring. J. Biol. Chem. 272, 12881-12884.
12. Dunn W.A. Jr. (1990a). Studies on the mechanisms of autophagy: Formation of the autophagic vacuole. J. Cell Biol. 110, 1923-1933.
13. Dunn W.A. Jr. (1990b). Studies on the mechanisms of autophagy: Maturation of the autophagic vacuole. J. Cell Biol. 110, 1935-1945.
14. EEC. (1986). Council Directive 86/609 on the approximation of laws. Regulations and administrative provisions of the Member States regarding the protection of animals used for experimental and other scientific purposes. Official Journal of the European Communities, L358, 1-29.
15. Einstein R. and Gabel C.A. (1991). Cell- and ligand-specific dephosphorylation of acid hydrolases: Evidence that the mannose 6-phosphatase is controlled by compartmentalization. J. Cell Biol. 112, 81-94.
16. Ericsson J.L.E. (1969). Studies on induced cellular autophagy. II. Characterization of the membranes bordering autophagosomes in parenchymal liver cells. Exp. Cell Res. 56, 393-405.
17. Fischer H.D., Gonzalez-Noriega A., Sly W.S. and Morrè D.J. (1980). Phosphomannosyl-enzyme receptors in rat liver. J. Biol. Chem. 255, 9608-9615.
18. Fiske C.H. and Subbarow Y. (1925). The colorimetric determination of phosphorus. J. Biol. Chem. 66, 375-400.
19. Glaumann H., Ahlberg J., Berkenstam A. and Henell F. (1985). Protein degradation in the lysosomes. Comparison between morphometric and biochemical assessments. J. Ultrastruct. Res. 91, 253.
20. Gonzalez-Noriega A. and Michalak C. (2001). Mannose 6-phosphate-independent endocytosis of beta glucuronidase. II. Purification of a cation-dependent receptor from bovine liver. Biochim. Biophys. Acta 1538, 152-161.
21. Gonzalez-Noriega A., Coutino R., Saavedra V.M. and Barrera R. (1989) Adsorptive endocytosis of lysosomal enzymes by human fibroblasts: Presence of two different functional systems that deliver an acid hydrolase to lysosomes. Arch. Biochem. Biophys. 268, 649-658.
22. Gonzalez-Noriega A., Ferrera P., Coutino R. and Michalak C. (1993). Isolation of an inhibitor for the independent mannose 6-phosphate receptor endocytosis of bovine beta-glucuronidase by human fibroblasts. Arch. Biochem. Biophys. 306, 331-336.
23. Gordon P.B., Holen I., Fosse M., Rotnes J.S. and Seglen P.O. (1993). Dependence of hepatocytic autophagy on intracellularly sequestered calcium. J. Biol. Chem. 268, 26107-26112.
24. Griffiths G., Hoflack B., Simons K., Mellman I. and Kornfeld S. (1988). The mannose 6-phosphate receptor and the biogenesis of lysosomes. Cell 52, 329-341.
25. Griffiths G., Hollinshead R., Hemmings B.A. and Nigg E.A. (1990). Ultrastructural localization of the regulatory (RII) subunit of cyclic AMP-dependent protein kinase to subcellular compartments active in endocytosis and recycling of membranes receptors. J. Cell Sci. 96, 691-703.
26. Hill A.B. (1967). Principles of Medical Statistics. Oxford University Press. New York.
27. Hoffman B.B. and Lefkowitz R.J. (1996). Catecholamines, sympathomimetic drugs, and adrenergic receptor antagonists. In: Goodman and Gilman's The Pharmacological Basis of Therapeutics. Hardman J.G. and Limbird L.E. (eds). McGraw-Hill Co. Inc. N.York. pp 199-248.
28. Holen I., Gordon P.B., Stromhaug P.E. and Seglen P.O. (1996). Role of cAMP in the regulation of hepatocytic autophagy. Eur. J. Biochem. 236, 163-170.
29. Holen I., Gordon P.B. and Seglen P.O. (1992). Protein kinase-dependent effects of okadaic acid on hepatocytic autophagy and cytoskeletal integrity. Biochem. J. 284, 633-636.
30. Hugon J.S., Borgers M. and Maestracci D. (1970). Glucose 6-phosphatase and thiamine pyrophosphatase activities in the jejunal epithelium of the mouse. J. Histochem. Cytochem. 18, 361-364.
31. Inbal B., Bialik S., Sabanay I., Shani G. and Kimchi A. (2002). DAP kinase and DRP-1 mediate membrane blebbing and the formation of autophagic vesicles during programmed cell death. J. Cell Biol. 157, 455-468.
32. Institute of Laboratory Animal Resources. (1996). Guide for the Care and Use of Laboratory Animals. National Academy Press. Washington, D.C.
33. 2+ entry in Madin Darby canine kidney cells. Cell. Signal. 12, 265-269.
34. Jeffrey P.L., Brown D.H. and Illingworth-Brown B. (1970). Studies of lysosomal alpha glucosidase. I. Purification and properties of the rat liver enzyme. Biochemistry 9, 1403-1415.
35. Jonas A.J., Conrad P. and Jobe H. (1990). Neutral-sugar transport by rat liver lysosomes. Biochem. J. 272, 323-326.
36. Jungmann R.A., Constantinou A.I., Squinto S.P., Kwast-Welfeld J. and Schweppe J.S. (1986). Regulation of lactate dehydrogenase gene expression by cAMP-dependent protein kinase subunits. In: Metabolic Regulation: Application of Recombinant DNA Techniques. Ann. NY Acad. Sci. 478, 147-161.
37. Kalamidas S.A. and Kotoulas O.B. (1999). The degradation of glycogen in the lysosomes of newborn rat hepatocytes: Glycogen-, maltose-and isomaltose-hydrolyzing acid alpha glucosidase activities in liver. Histol. Histopathol. 14, 23-30.
38. Kalamidas S.A. and Kotoulas O.B. (2000a) Studies on the breakdown of glycogen in the lysosomes. The effects of hydrocortisone. Histol. Histopathol. 15, 29-35.
39. Kalamidas S.A. and Kotoulas O.B. (2000b). Glycogen autophagy in newborn rat hepatocytes. Histol. Histopathol. 15, 1011-1018.
40. Kalamidas S.A., Kotoulas O.B., Kotoulas A.O. and Maintas D.B. (1994). The breakdown of glycogen in the lysosomes of newborn rat hepatocytes: The effects of glucose, cyclic 3′ 5′ -AMP and caffeine. Histol. Histopathol. 9, 691-698.
41. Kalamidas S.A., Kotoulas O.B. and Hann A.C. (2002). Studies on glycogen autophagy. The effects of phorbol myristate acetate, ionophore A23187 or phentolamine. Microsc. Res. Tech. 57, 507-511.
42. Kim J. and Klionsky D.J. (2000). Autophagy, cytoplasm-to-vacuole targeting pathway, and pexophagy in yeast and mammalian cells. Annu. Rev. Biochem. 69, 303-342.
43. Klempner N.S. (1985). An adenosine triphosphate-dependent calcium uptake pump in human neutrophil lysosomes. J. Clin. Invest. 76, 303-310.
44. Kornfeld S. (1986). Trafficking of lysosomal enzymes in normal and diseased states. J. Clin. Invest. 77, 1-6.
45. Kornfeld S. (1992). Structure and function of the mannose 6-phosphate/insulin like growth factor II receptors. Annu. Rev. Biochem. 61, 307-330.
46. Kotoulas A.O., Kotoulas O.B. and Kalamidas S. (1991). An electron microscopic and biochemical study of the effects of cyclic 3′5′-AMP, ergotamine or propranolol on the lysosomes of newborn rat hepatocytes. Histol. Histopathol. 6, 421-426.
47. Kotoulas O.B. (1981). An electron microscopic and biochemical study of the effects of insulin on newborn rat hepatocytes. Pathol. Res. Pract. 172, 138-147.
48. Kotoulas O.B. (1986). The effects of cyclic 3′,5′-AMP on the lysosomes of newborn rat hepatocytes. J. Ultrastruct. Res. 97, 210-215.
49. Kotoulas O.B. (1988). Effects of actinomycin D on the lysosomes of newborn rat hepatocytes. Anat. Rec. 220, 103-107.
50. Kotoulas O.B. and Phillips M.J. (1971). Fine structural aspects of the mobilization of hepatic glycogen. I. Acceleration of glycogen breakdown. Am. J. Pathol. 63, 1-7.
51. Kotoulas O.B., Ho J., Adachi F., Weigensberg B.I. and Phillips M.J. (1971). Fine structural aspects of the mobilization of hepatic glycogen. II. Inhibition of glycogen breakdown. Am. J. Pathol. 63, 23-34.
52. Lagast H., Pozzan T., Waldvogel F.A. and Lew P.D. (1984). Phorbol myristate acetate stimulates ATP-dependent calcium transport by the plasma membrane of neutrophils. J. Clin. Invest. 73, 878-883.
53. Ma Z., Grubb J.H. and Sly W.S. (1992). Divalent cation-dependent stimulation of ligand binding to the 46-kDa mannose 6-phosphate receptor correlates with divalent cation-dependent tetramerization. J. Biol. Chem. 267, 19017-19022.
54. 2+-release channel function. Biochem. J. 337, 345-361.
55. Maintas D.B., Kotoulas O.B. and Kotoulas A.O. (1993). A quantitative description of the insulin-induced ultrastructural changes in newborn rat hepatocytes. Histol. Histopathol. 8, 235-242.
56. Mednieks M.I., Jungmann R.A., Fischer C. and Hand A.R. (1989). Immunogold localization of the type II regulatory subunit of cyclic AMP-dependent protein kinase. Monoclonal antibody characterization and RII distribution in rat parotid cells. J. Histochem. Cytochem. 37, 339-346.
57. Michalak M., Corbett E.F., Mesaeli N., Nakamura K. and Opas M. (1999). Calreticulin: One protein, one gene, many functions. Biochem. J. 344, 281-292.
58. Mithieux G., Vega F.V. and Riou J.P. (1990). The liver glucose-6-phosphatase of intact microsomes is inhibited and displays sigmoid kinetics in the presence of a-ketoglutarate-magnesium and oxaloacetate-magnesium chelates. J. Biol. Chem. 265, 20364-20368.
59. Ockerman P.A. (1965). Glucose 6-phosphatase in human jejunal mucosa. Properties demonstrating the specific character of the enzyme activity. Biochim. Biophys. Acta 105, 22-33.
60. Pfeifer U. (1971). Tageszeitliche rhythmik der zellularen autophagie. Naturwissenschaften 58, 152.
61. Rosenfeld E.L. (1964). Control of glycogen metabolism. Ciba Foundation Symposium. Whelan W.J. and Cameron M.P. (eds). J. & A. Churchill Ltd. London.
62. Sakai M., Luo S.Q., Tanaka T. and Ogawa K. (1989). Distribution of electric changes and concanavalin A binding sites on autophagic vacuoles and lysosomes in mouse hepatocytes. Exp. Cell Res. 185, 143-153.
63. 2+ regulated. Am. J. Physiol. 274, E459-468.
64. Shelburne J.D., Arstila A.U. and Trump B.F. (1973). Studies on cellular autophagocytosis: Cyclic AMP- and dibutyryl cyclic AMP-stimulated autophagy in rat liver. Am. J. Pathol. 72, 521-534.
65. Skalhegg B.S. and Tasken K. (1997). Specificity in the cAMP/PKA signaling pathway. Differential expression, regulation, and subcellular localization of subunits of PKA. Front. Biosci. 2, d331-342.
66. Sly W.S. (1985). Receptor-mediated sorting and transport of acid hydrolases to lysosomes. In: Protein Transport and Secretion. Gething M-J. (ed). Cold Spring Harbor Lab. New York. pp 121-125.
67. Spaulding S.W. (1993). The ways in which hormones change cyclic adenosine 3′,5′-monophosphate-dependent protein kinase subunits and how such changes affect cell behavour. Endocr. Rev. 14, 632-650.
68. St-Denis J.-F., Berteloot A., Vidal H., Annabi B. and VandeWerve G. (1995). Glucose transport and glucose 6-phosphate hydrolysis in intact rat liver microsomes. J. Biol. Chem. 270, 21092-21097.
69. 2+ concentrations. J. Biol. Chem. 264, 6033-6036.
70. Wang Z., Wilson W.A., Fujino M.A. and Roach P.J. (2001). Antagonistic controls of autophagy and glycogen accumulation by Snf1p, the yeast homolog of AMP-activated protein kinase and the Cyclin-dependent kinase Pho85p. Mol. Cel. Biol. 21, 5742-5752.
71. Warren L. (1989). Stimulated secretion of lysosomal enzymes by cells in culture. J. Biol. Chem. 264, 8835-8842.
72. Weibel E.R. (1969). Stereological principles for morphometry in electron microscopic cytology. Int. Rev. Cytol. 26, 235-302.
73. Weibel E.R. and Gomez D.M. (1962). A principle for counting tissue structures on random sections. J. Appl. Physiol. 17, 343-348.
74. Wells W.W., Collins C.A. and Kurtz J.W. (1981). Metabolic regulation of lysosomal activity. In: Lysosomes and Lysosomal Storage Diseases. Callahan J.W. and Lowden J.A. (eds). Raven Press. New York. pp 17-30.
75. Zakim D. and Vessey D.A. (1973). Techniques for the characterization of UDP-glucuronyltransferase, glucose-6-phosphatase, and other tightly-bound microsomal enzymes. Met. Biochem. Anal. 21, 1-37.