메뉴 건너뛰기




Volumn 14, Issue 2, 2003, Pages 101-107

Mechanisms of free radical production in the vascular wall

Author keywords

Free radicals; NAD(P)H oxidase; Nitric oxide synthase; Vascular dysfunction

Indexed keywords

CYTOCHROME P450 REDUCTASE; FREE RADICAL; LIPOXYGENASE; NITRIC OXIDE SYNTHASE; PROSTAGLANDIN SYNTHASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; XANTHINE OXIDASE;

EID: 0038070157     PISSN: 09546928     EISSN: None     Source Type: Journal    
DOI: 10.1097/00019501-200304000-00002     Document Type: Review
Times cited : (5)

References (42)
  • 1
  • 2
    • 0033552883 scopus 로고    scopus 로고
    • Atherosclerosis-an inflammatory disease
    • Ross R. Atherosclerosis-an inflammatory disease. N Engl J Med 1999; 340:115-126.
    • (1999) N Engl J Med , vol.340 , pp. 115-126
    • Ross, R.1
  • 3
    • 0033570271 scopus 로고    scopus 로고
    • Oxidative stress as a regulator of gene expression in the vasculature
    • Kunsch C, Medford RM. Oxidative stress as a regulator of gene expression in the vasculature. Circ Res 1999; 85:753-766.
    • (1999) Circ Res , vol.85 , pp. 753-766
    • Kunsch, C.1    Medford, R.M.2
  • 4
    • 0031941373 scopus 로고    scopus 로고
    • Validation of lucigenin (bis-N-methylacridinium) as a chemilumigenic probe for detecting superoxide anion radical production by enzymatic and cellular systems
    • Li Y, Zhu H, Kuppusamy P, Roubaud V, Zweier JL, Trush MA. Validation of lucigenin (bis-N-methylacridinium) as a chemilumigenic probe for detecting superoxide anion radical production by enzymatic and cellular systems. J Biol Chem 1998; 273:2015-2023.
    • (1998) J Biol Chem , vol.273 , pp. 2015-2023
    • Li, Y.1    Zhu, H.2    Kuppusamy, P.3    Roubaud, V.4    Zweier, J.L.5    Trush, M.A.6
  • 5
    • 0029347181 scopus 로고
    • Flavoprotein structure and mechanism. 4. Xanthine oxidase and xanthine dehydrogenase
    • Hille R, Nishino T. Flavoprotein structure and mechanism. 4. Xanthine oxidase and xanthine dehydrogenase. FASEB J 1995; 9:995-1003.
    • (1995) FASEB J , vol.9 , pp. 995-1003
    • Hille, R.1    Nishino, T.2
  • 6
    • 0027181186 scopus 로고
    • Evidence that mitochondrial respiration is a source of potentially toxic oxygen free radicals in intact rabbit hearts subjected to ischemia and reflow
    • Ambrosio G, Zweier JL, Duilio C, Kuppusamy P, Santoro G, Elia PP, et al. Evidence that mitochondrial respiration is a source of potentially toxic oxygen free radicals in intact rabbit hearts subjected to ischemia and reflow. J Biol Chem 1993; 268:18532-18541.
    • (1993) J Biol Chem , vol.268 , pp. 18532-18541
    • Ambrosio, G.1    Zweier, J.L.2    Duilio, C.3    Kuppusamy, P.4    Santoro, G.5    Elia, P.P.6
  • 7
    • 0028297220 scopus 로고
    • Measurement and characterization of free radical generation in reoxygenated human endothelial cells
    • Zweier JL, Kuppusamy P, Thompson-Gorman S, Klunk D, Lutty GA. Measurement and characterization of free radical generation in reoxygenated human endothelial cells. Am J Physiol 1994; 266:C700-C708.
    • (1994) Am J Physiol , vol.266
    • Zweier, J.L.1    Kuppusamy, P.2    Thompson-Gorman, S.3    Klunk, D.4    Lutty, G.A.5
  • 8
    • 0027938706 scopus 로고
    • Determination of the mechanism of free radical generation in human aortic endothelial cells exposed to anoxia and reoxygenation
    • Zweier JL, Broderick R, Kuppusamy P, Thompson-Gorman S, Lutty GA. Determination of the mechanism of free radical generation in human aortic endothelial cells exposed to anoxia and reoxygenation. J Biol Chem 1994; 269:24156-24162.
    • (1994) J Biol Chem , vol.269 , pp. 24156-24162
    • Zweier, J.L.1    Broderick, R.2    Kuppusamy, P.3    Thompson-Gorman, S.4    Lutty, G.A.5
  • 9
    • 0000104045 scopus 로고
    • Measurement of endothelial cell free radical generation: Evidence for a central mechanism of free radical injury in postischemic tissues
    • Zweier JL, Kuppusamy P, Lutty GA. Measurement of endothelial cell free radical generation: evidence for a central mechanism of free radical injury in postischemic tissues. Proc Natl Acad Sci USA 1988; 85:4046-4050.
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 4046-4050
    • Zweier, J.L.1    Kuppusamy, P.2    Lutty, G.A.3
  • 11
    • 0026515846 scopus 로고
    • Regulation of xanthine dehydrogenase and xanthine oxidase activity and gene expression in cultured rat pulmonary endothelial cells
    • Dupont GP, Huecksteadt TP, Marshall BC, Ryan US, Michael JR, Hoidal JR. Regulation of xanthine dehydrogenase and xanthine oxidase activity and gene expression in cultured rat pulmonary endothelial cells. J Clin Invest 1992; 89:197-202.
    • (1992) J Clin Invest , vol.89 , pp. 197-202
    • Dupont, G.P.1    Huecksteadt, T.P.2    Marshall, B.C.3    Ryan, U.S.4    Michael, J.R.5    Hoidal, J.R.6
  • 12
    • 0032516037 scopus 로고    scopus 로고
    • Xanthine oxidase activity associated with arterial blood pressure in spontaneously hypertensive rats
    • Suzuki H, DeLano FA, Parks DA, Jamshidi N, Granger DN, Ishii H, et al. Xanthine oxidase activity associated with arterial blood pressure in spontaneously hypertensive rats. Proc Natl Acad Sci USA 1998; 95:4754-4759.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 4754-4759
    • Suzuki, H.1    DeLano, F.A.2    Parks, D.A.3    Jamshidi, N.4    Granger, D.N.5    Ishii, H.6
  • 13
    • 0035096812 scopus 로고    scopus 로고
    • Endothelial dysfunction and xanthine oxidoreductase activity in rats with human renin and angiotensinogen genes
    • Mervaala EM, Cheng ZJ, Tikkanen I, Lapatto R, Nurminen K, Vapaatalo H, et al. Endothelial dysfunction and xanthine oxidoreductase activity in rats with human renin and angiotensinogen genes. Hypertension 2001; 37:414-418.
    • (2001) Hypertension , vol.37 , pp. 414-418
    • Mervaala, E.M.1    Cheng, Z.J.2    Tikkanen, I.3    Lapatto, R.4    Nurminen, K.5    Vapaatalo, H.6
  • 14
    • 0034534036 scopus 로고    scopus 로고
    • Cellular distribution, metabolism and regulation of the xanthine oxidoreductase enzyme system
    • Pritsos CA. Cellular distribution, metabolism and regulation of the xanthine oxidoreductase enzyme system. Chem Biol Interact 2000; 129:195-208.
    • (2000) Chem Biol Interact , vol.129 , pp. 195-208
    • Pritsos, C.A.1
  • 15
    • 0034634281 scopus 로고    scopus 로고
    • Endothelial dysfunction in cardiovascular diseases: The role of oxidant stress
    • Cai H, Harrison DG. Endothelial dysfunction in cardiovascular diseases: the role of oxidant stress. Circ Res 2000; 87:840-844.
    • (2000) Circ Res , vol.87 , pp. 840-844
    • Cai, H.1    Harrison, D.G.2
  • 16
    • 0033796250 scopus 로고    scopus 로고
    • Mitochondrial free radical generation, oxidative stress, and aging
    • Cadenas E, Davies KJ. Mitochondrial free radical generation, oxidative stress, and aging. Free Radic Biol Med 2000; 29:222-230.
    • (2000) Free Radic Biol Med , vol.29 , pp. 222-230
    • Cadenas, E.1    Davies, K.J.2
  • 17
    • 0000098037 scopus 로고
    • Direct measurement of free radical generation following reperfusion of ischemic myocardium
    • Zweier JL, Flaherty JT, Weisfeldt ML. Direct measurement of free radical generation following reperfusion of ischemic myocardium. Proc Natl Acad Sci USA 1987; 84:1404-1407.
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 1404-1407
    • Zweier, J.L.1    Flaherty, J.T.2    Weisfeldt, M.L.3
  • 18
    • 0027391605 scopus 로고
    • Hyperoxic sheep pulmonary microvascular endothelial cells generate free radicals via mitochondrial electron transport
    • Sanders SP, Zweier JL, Kuppusamy P, Harrison SJ, Bassett DJ, Gabrielson EW, et al. Hyperoxic sheep pulmonary microvascular endothelial cells generate free radicals via mitochondrial electron transport. J Clin Invest 1993; 91:46-52.
    • (1993) J Clin Invest , vol.91 , pp. 46-52
    • Sanders, S.P.1    Zweier, J.L.2    Kuppusamy, P.3    Harrison, S.J.4    Bassett, D.J.5    Gabrielson, E.W.6
  • 19
    • 0034643340 scopus 로고    scopus 로고
    • Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage
    • Nishikawa T, Edelstein D, Du XL, Yamagishi S, Matsumura T, Kaneda Y, et al. Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage. Nature 2000; 404:787-790.
    • (2000) Nature , vol.404 , pp. 787-790
    • Nishikawa, T.1    Edelstein, D.2    Du, X.L.3    Yamagishi, S.4    Matsumura, T.5    Kaneda, Y.6
  • 21
    • 0032475865 scopus 로고    scopus 로고
    • 2+/calmodulin-dependent and tetrahydrobiopterin regulatory process
    • 2+/calmodulin-dependent and tetrahydrobiopterin regulatory process. J Biol Chem 1998; 273:25804-25808.
    • (1998) J Biol Chem , vol.273 , pp. 25804-25808
    • Xia, Y.1    Tsai, A.L.2    Berka, V.3    Zweier, J.L.4
  • 22
    • 0033527413 scopus 로고    scopus 로고
    • Oxidation of tetrahydrobiopterin by peroxynitrite: Implications for vascular endothelial function
    • Milstien S, Katusic Z. Oxidation of tetrahydrobiopterin by peroxynitrite: implications for vascular endothelial function. Biochem Biophys Res Commun 1999; 263:681-684.
    • (1999) Biochem Biophys Res Commun , vol.263 , pp. 681-684
    • Milstien, S.1    Katusic, Z.2
  • 23
    • 0033021938 scopus 로고    scopus 로고
    • Superoxide anion production is increased in a model of genetic hypertension: Role of the endothelium
    • Kerr S, Brosnan MJ, McIntyre M, Reid JL, Dominiczak AF, Hamilton CA. Superoxide anion production is increased in a model of genetic hypertension: role of the endothelium. Hypertension 1999; 33:1353-1358.
    • (1999) Hypertension , vol.33 , pp. 1353-1358
    • Kerr, S.1    Brosnan, M.J.2    McIntyre, M.3    Reid, J.L.4    Dominiczak, A.F.5    Hamilton, C.A.6
  • 24
    • 0031002421 scopus 로고    scopus 로고
    • Superoxide and peroxynitrite generation from inducible nitric oxide synthase in macrophages
    • Xia Y, Zweier JL. Superoxide and peroxynitrite generation from inducible nitric oxide synthase in macrophages. Proc Natl Acad Sci USA 1997; 94:6954-6958.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 6954-6958
    • Xia, Y.1    Zweier, J.L.2
  • 25
    • 0034677947 scopus 로고    scopus 로고
    • NAD(P)H oxidase: Role in cardiovascular biology and disease
    • Griendling KK, Sorescu D, Ushio-Fukai M. NAD(P)H oxidase: role in cardiovascular biology and disease. Circ Res 2000; 86:494-501.
    • (2000) Circ Res , vol.86 , pp. 494-501
    • Griendling, K.K.1    Sorescu, D.2    Ushio-Fukai, M.3
  • 26
    • 0029661428 scopus 로고    scopus 로고
    • p22phox is a critical component of the superoxide-generating NADH/NADPH oxidase system and regulates angiotensin II-induced hypertrophy in vascular smooth muscle cells
    • Ushio-Fukai M, Zafari AM, Fukui T, Ishizaka N, Griendling KK. p22phox is a critical component of the superoxide-generating NADH/NADPH oxidase system and regulates angiotensin II-induced hypertrophy in vascular smooth muscle cells. J Biol Chem 1996; 271:23317-23321.
    • (1996) J Biol Chem , vol.271 , pp. 23317-23321
    • Ushio-Fukai, M.1    Zafari, A.M.2    Fukui, T.3    Ishizaka, N.4    Griendling, K.K.5
  • 27
    • 0028138966 scopus 로고
    • The functional expression of p47-phox and p67-phox may contribute to the generation of superoxide by an NADPH oxidase-like system in human fibroblasts
    • Jones SA, Wood JD, Coffey MJ, Jones OT. The functional expression of p47-phox and p67-phox may contribute to the generation of superoxide by an NADPH oxidase-like system in human fibroblasts. FEBS Lett 1994; 355:178-182.
    • (1994) FEBS Lett , vol.355 , pp. 178-182
    • Jones, S.A.1    Wood, J.D.2    Coffey, M.J.3    Jones, O.T.4
  • 28
    • 0032051656 scopus 로고    scopus 로고
    • Expression of functional neutrophil-type NADPH oxidase in cultured rat coronary microvascular endothelial cells
    • Bayraktutan U, Draper N, Lang D, Shah AM. Expression of functional neutrophil-type NADPH oxidase in cultured rat coronary microvascular endothelial cells. Cardiovasc Res 1998; 38:256-262.
    • (1998) Cardiovasc Res , vol.38 , pp. 256-262
    • Bayraktutan, U.1    Draper, N.2    Lang, D.3    Shah, A.M.4
  • 31
    • 0032104153 scopus 로고    scopus 로고
    • Oscillatory and steady laminar shear stress differentially affect human endothelial redox state: Role of a superoxide-producing NADH oxidase
    • De Keulenaer GW, Chappell DC, Ishizaka N, Nerem RM, Alexander RW, Griendling KK. Oscillatory and steady laminar shear stress differentially affect human endothelial redox state: role of a superoxide-producing NADH oxidase. Circ Res 1998; 82:1094-1101.
    • (1998) Circ Res , vol.82 , pp. 1094-1101
    • De Keulenaer, G.W.1    Chappell, D.C.2    Ishizaka, N.3    Nerem, R.M.4    Alexander, R.W.5    Griendling, K.K.6
  • 34
    • 0031015288 scopus 로고    scopus 로고
    • p22phox mRNA expression and NADPH oxidase activity are increased in aortas from hypertensive rats
    • Fukui T, Ishizaka N, Rajagopalan S, Laursen JB, Capers Q, Taylor WR, et al. p22phox mRNA expression and NADPH oxidase activity are increased in aortas from hypertensive rats. Circ Res 1997; 80:45-51.
    • (1997) Circ Res , vol.80 , pp. 45-51
    • Fukui, T.1    Ishizaka, N.2    Rajagopalan, S.3    Laursen, J.B.4    Capers, Q.5    Taylor, W.R.6
  • 35
    • 0033586639 scopus 로고    scopus 로고
    • Increased NADH-oxidase-mediated superoxide production in the early stages of atherosclerosis: Evidence for involvement of the renin-angiotensin system
    • Warnholtz A, Nickenig G, Schulz E, Macharzina R, Brasen JH, Skatchkov M, et al. Increased NADH-oxidase-mediated superoxide production in the early stages of atherosclerosis: evidence for involvement of the renin-angiotensin system. Circulation 1999; 99:2027-2033.
    • (1999) Circulation , vol.99 , pp. 2027-2033
    • Warnholtz, A.1    Nickenig, G.2    Schulz, E.3    Macharzina, R.4    Brasen, J.H.5    Skatchkov, M.6
  • 36
    • 0034599040 scopus 로고    scopus 로고
    • A variant of p22(phox), involved in generation of reactive oxygen species in the vessel wall, is associated with progression of coronary atherosclerosis
    • Cahilly C, Ballantyne CM, Lim DS, Gotto A, Marian AJ. A variant of p22(phox), involved in generation of reactive oxygen species in the vessel wall, is associated with progression of coronary atherosclerosis. Circ Res 2000; 86:391-395.
    • (2000) Circ Res , vol.86 , pp. 391-395
    • Cahilly, C.1    Ballantyne, C.M.2    Lim, D.S.3    Gotto, A.4    Marian, A.J.5
  • 37
    • 0343527886 scopus 로고    scopus 로고
    • C242T polymorphism of NADPH oxidase p22 PHOX gene and ischemic cerebrovascular disease in the Japanese population
    • Ito D, Murata M, Watanabe K, Yoshida T, Saito I, Tanahashi N, et al. C242T polymorphism of NADPH oxidase p22 PHOX gene and ischemic cerebrovascular disease in the Japanese population. Stroke 2000; 31:936-939.
    • (2000) Stroke , vol.31 , pp. 936-939
    • Ito, D.1    Murata, M.2    Watanabe, K.3    Yoshida, T.4    Saito, I.5    Tanahashi, N.6
  • 39
    • 0033578905 scopus 로고    scopus 로고
    • Overexpression of human catalase inhibits proliferation and promotes apoptosis in vascular smooth muscle cells
    • Brown MR, Miller FJ, Li WG, Ellingson AN, Mozena JD, Chatterjee P, et al. Overexpression of human catalase inhibits proliferation and promotes apoptosis in vascular smooth muscle cells. Circ Res 1999; 85:524-533.
    • (1999) Circ Res , vol.85 , pp. 524-533
    • Brown, M.R.1    Miller, F.J.2    Li, W.G.3    Ellingson, A.N.4    Mozena, J.D.5    Chatterjee, P.6
  • 40
    • 0034749387 scopus 로고    scopus 로고
    • Oxidized low density lipoprotein induces apoptosis via generation of reactive oxygen species in vascular smooth muscle cells
    • Hsieh CC, Yen MH, Yen CH, Lau YT. Oxidized low density lipoprotein induces apoptosis via generation of reactive oxygen species in vascular smooth muscle cells. Cardiovasc Res 2001; 49:135-145.
    • (2001) Cardiovasc Res , vol.49 , pp. 135-145
    • Hsieh, C.C.1    Yen, M.H.2    Yen, C.H.3    Lau, Y.T.4
  • 41
    • 0035910620 scopus 로고    scopus 로고
    • Endothelium-derived hyperpolarizing factor synthase (Cytochrome P450 2C9) is a functionally significant source of reactive oxygen species in coronary arteries
    • Fleming I, Michaelis UR, Bredenkotter D, Fisslthaler B, Dehghani F, Brandes RP, et al. Endothelium-derived hyperpolarizing factor synthase (Cytochrome P450 2C9) is a functionally significant source of reactive oxygen species in coronary arteries. Circ Res 2001; 88:44-51.
    • (2001) Circ Res , vol.88 , pp. 44-51
    • Fleming, I.1    Michaelis, U.R.2    Bredenkotter, D.3    Fisslthaler, B.4    Dehghani, F.5    Brandes, R.P.6
  • 42


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.