Destabilization of Nav1.7 sodium channel α-subunit mRNA by constitutive phosphorylation of extracellular signal-regulated kinase: Negative regulation of steady-state level of cell surface functional sodium channels in adrenal chromaffin cells

Molecular Pharmacology

Volumn 63, Issue 5, 2003, Pages 1125-1136

  Yanagita, Toshihiko ^a   Kobayashi, Hideyuki ^a   Uezono, Yasuhito ^a   Yokoo, Hiroki ^a   Sugano, Takashi ^a   Saitoh, Tomokazu ^a   Minami, Shin Ichi ^a   Shiraishi, Seiji ^a   Wada, Akihiko ^a  

^a UNIVERSITY OF MIYAZAKI   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; CYCLOHEXIMIDE; ISOPROTEIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; PTYCHODISCUS BREVIS TOXIN 3; SAXITOXIN; SODIUM CHANNEL; SODIUM ION; TOXIN; UNCLASSIFIED DRUG; VERATRIDINE;

ALPHA CHAIN; ANIMAL CELL; ARTICLE; BETA CHAIN; BINDING KINETICS; CATTLE; CELL SURFACE; CHROMAFFIN CELL; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; IMMUNOBLOTTING; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN STABILITY; SODIUM TRANSPORT;

ADRENAL GLANDS; ANIMALS; BUTADIENES; CATIONS; CATTLE; CELLS, CULTURED; CHROMAFFIN CELLS; CYCLOHEXIMIDE; DOSE-RESPONSE RELATIONSHIP, DRUG; FLAVONOIDS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; NITRILES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROTEIN SUBUNITS; PROTEIN SYNTHESIS INHIBITORS; RECEPTORS, NICOTINIC; RNA STABILITY; RNA, MESSENGER; SAXITOXIN; SODIUM; SODIUM CHANNELS; TIME FACTORS; TRITIUM; UP-REGULATION;

EID: 0038069010     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.63.5.1125     Document Type: Article

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