Renal function in proteinuric glomerular diseases correlates to the changes in urine IgM excretion but not to the changes in the degree of albuminuria

Clinical Nephrology

Volumn 59, Issue 5, 2003, Pages 345-352

  Bakoush, Omran ^a   Torffvit, O ^a   Rippe, B ^a   Tencer, J ^a  

^a LUND UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Albuminuria; Glomerulopathy; IgM; Proteinuria; 1 microglobulin

Indexed keywords

CREATININE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; IMMUNOGLOBULIN M; IMMUNOSUPPRESSIVE AGENT;

ADULT; ARTICLE; CLINICAL ARTICLE; CLINICAL OBSERVATION; CONTROLLED STUDY; CORRELATION COEFFICIENT; CREATININE BLOOD LEVEL; FEMALE; FOLLOW UP; GLOMERULOPATHY; GLOMERULUS CAPILLARY; GLOMERULUS FILTRATION RATE; HUMAN; KIDNEY BIOPSY; KIDNEY FAILURE; KIDNEY FUNCTION; MALE; PROGNOSIS; PROTEIN URINE LEVEL; PROTEINURIA; REGRESSION ANALYSIS; SURVIVAL; URINALYSIS; URINARY EXCRETION;

EID: 0038057597     PISSN: 03010430     EISSN: None     Source Type: Journal    
DOI: 10.5414/CNP59345     Document Type: Article

References (30)

1. Alamartine E, Sabatier JC, Guerin C, Berliet JM, Berthoux F 1991 Prognostic factors in mesangial IgA glomerulonephritis: an extensive study with univariate and multivariate analyses. Am J Kidney Dis 18: 12-19
2. Bakoush O, Grubb A, Rippe B, Tencer J 2001a Urine excretion of protein HC in proteinuric glomerular diseases correlates to urine IgG but not to albuminuria. Kidney Int 60: 1904-1909
3. Bakoush O, Torffvit O, Rippe B Tencer J 2001b High proteinuria selectivity index based upon IgM is a strong predictor of poor renal survival in glomerular diseases. Nephrol Dial Transplant 16: 1357-1363
4. Bazzi C, Petrini C, Rizza V, Arrigo G, D'Amico G 2000 A modem approach to selectivity of proteinuria and tubulointerstitial damage in nephrotic syndrome. Kidney Int 58: 1732-1741
5. Bos H, Andersen S, Rossing P, De Zeeuw D, Parving HH, De Jong PE, Navis G 2000 Role of patient factors in therapy resistance to antiproteinuric intervention in nondiabetic and diabetic nephropathy. Kidney Int Suppl 75: S32-37
6. Couser WG 1998 Pathogenesis of glomerular damage in glomerulonephritis. Nephrol Dial Transplant 13 (Suppl 1): 10-15
7. Deen WM, Bridges CR, Brenner BM, Myers BD 1985 Heteroporous model of glomerular size selectivity: application to normal and nephrotic humans. Am J Physiol 249: F374-389
8. Hjorth L, Helin I, Grubb A 2000 Age-related reference limits for urine levels of albumin orosomucoid immunoglobulin G and protein HC in children. Scand J Clin Lab Invest 60: 65-73
9. Hofmann W, Rossmuller B, Guder WG, Edel HH 1992 A new strategy for characterizing proteinuria and haematuria from a single pattern of defined proteins in urine. Eur J Clin Chem Clin Biochem 30: 707-712
10. Keane WF 2000 Proteinuria: its clinical importance and role in progressive renal disease. Am J Kidney Dis 35: S97-105
11. Levey AS, Bosch JP, Lewis JB, Greene T, Rogers N, Roth D 1999 A more accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction equation. Modification of Diet in Renal Disease Study Group. Ann Intern Med 130: 461-470
12. Mallick NP, Short CD, Hunt LP 1987 How far since Ellis? The Manchester Study of glomerular disease. Nephron 46: 113-124
13. Manjunath G, Sarnak MJ, Levey AS 2001 Prediction equations to estimate glomerular filtration rate: an update. Curr Opin Nephrol Hypertens 10: 785-792
14. Nangaku M, Pippin J, Couser WG 1999 Complement membrane attack complex C5b-9 mediates interstitial disease in experimental nephrotic syndrome. J Am Soc Nephrol 10: 2323-2331
15. Neelakantappa K, Gallo GR, Baldwin DS 1988 Proteinuria in IgA nephropathy. Kidney Int 33: 716-721
16. Newman DJ, Pugia MJ, Lott JA, Wallace JF, Hiar AM 2000 Urinary protein and albumin excretion corrected by creatinine and specific gravity. Clin Chim Acta 294: 139-155
17. Okada H, Suzuki H, Konishi K, Sakaguchi H, Saruta T 1992 Histological alterations in renal specimens as indicators of prognosis of IgA nephropathy. Clin Nephrol 37: 235-238
18. Okuda S, Oochi N, Wakisaka M, Kanai H, Tamaki K, Nagase S, Onoyama K, Fujishima M 1992 Albuminuria is not an aggravating factor in experimental focal glomeralosclerosis and hyalinosis. J Lab Clin Med 119: 245-253
19. Price CP, Spencer K, Whicher J 1983 Light-scattering immunoassay of specific proteins: a review. Ann Clin Biochem 20: 1-14
20. Remuzzi G, Bertani T 1998 Pathophysiology of progressive nephropathies. N Engl J Med 339: 1448-1456
21. Ruggenenti P, Gaspari F, Perna A, Remuzzi G 1998 Cross sectional longitudinal study of spot morning urine protein: creatinine ratio 24-hour urine protein excretion rate glomerular filtration rate and end stage renal failure in chronic renal disease in patients without diabetes. BMJ 316: 504-509
22. Schieppati A, Mosconi L, Perna A, Mecca G, Bertani T, Garattini S, Remuzzi G 1993 Prognosis of untreated patients with idiopathic membranous nephropathy. N Engl J Med 329: 85-99
23. Schurek HJ, Neumann KH, Flohr H, Zeh M, Stolte H 1992 The physiological and pathophysiological basis of glomerular permeability for plasma proteins and erythrocytes. Eur J Clin Chem Clin Biochem 30: 627-633
24. Steinhauslin F, Wauters JP 1995 Quantitation of proteinuria in kidney transplant patients: accuracy of the urinary protein/creatinine ratio. Clin Nephrol 43: 110-115
25. Svendsen P, Blirup-Jensen S 1991 Determination of human plasma proteins by turbidimetry and nephelometry. Dako, Copenhagen
26. 1-antitrypsin. Scand J Clin Lab Invest 56: 691-700
27. Tencer J, Frick IM, Oquist BW, Alm P, Rippe B 1998a Size-selectivity of the glomerular barrier to high molecular weight proteins: upper size limitations of shunt pathways. Kidney Int 53: 709-715
28. 2-macroglobulin or IgM is superior to the IgG-based index in differentiating glomerular diseases. Technical note. Kidney Int 54: 2098-2105
29. Tencer J, Bakoush O, Torffvit O 2000 Diagnostic and prognostic significance of proteinuria selectivity index in glomerular diseases. Clin Chim Acta 297: 73-83
30. Wang SN, LaPage J, Hirschberg R 2000 Role of glomerular ultrafiltration of growth factors in progressive interstitial fibrosis in diabetic nephropathy. Kidney Int 57: 1002-1014