Hydroquinone and catechol interfere with T cell cycle entry and progression through the G1 phase

Molecular Immunology

Volumn 39, Issue 16, 2003, Pages 995-1001

  McCue, Jesica M ^a   Lazis, Sabine ^a   Cohen, J John ^a   Modiano, Jaime F ^a   Freed, Brian M ^a  

^a UNIVERSITY OF COLORADO   (United States)

Author keywords

Cell cycle; Cigarette components; Immunomodulators; T lymphocyte

Indexed keywords

CATECHOL; CD69 ANTIGEN; CD71 ANTIGEN; CIGARETTE SMOKE; HYDROQUINONE; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR; MYC PROTEIN;

ANTIGEN EXPRESSION; ARTICLE; CELL CYCLE G1 PHASE; CELL VIABILITY; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; GENE EXPRESSION; GENE INDUCTION; HUMAN; HUMAN CELL; INHIBITION KINETICS; LYMPHOCYTE ACTIVATION; LYMPHOCYTE TRANSFORMATION; PRIORITY JOURNAL; RESPIRATORY TRACT INFECTION; RNA SYNTHESIS; T LYMPHOCYTE; UPREGULATION;

EID: 0038056186     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0161-5890(03)00046-4     Document Type: Article

References (36)

1. Baldwin C.I., Todd A., Bourke S., Allen A., Calvert J.E. Pigeon fanciers' lung: effects of smoking on serum and salivary antibody responses to pigeon antigens. Clin. Exp. Immunol. 113:1998;166-172.
2. Bouchard C., Thieke K., Maier A., Saffrich R., Hanley-Hyde J., Ansorge W., Reed S., Sicinski P., Bartek J., Eilers M. Direct induction of cyclin D2 by Myc contributes to cell cycle progression and sequestration of p27. EMBO J. 18:1999;5321-5333.
3. Brooks R.F. Continuous protein synthesis is required to maintain the probability of entry into S phase. Cell. 12:1977;311-317.
4. Coleman M.L., Sahai E.A., Yeo M., Bosch M., Dewar A., Olson M.F. Membrane blebbing during apoptosis results from caspase-mediated activation of ROCK I. Nat. Cell. Biol. 3:2001;339-345.
5. Daniele R.P., Dauber J.H., Altose M.D., Rowlands D.T. Jr., Gorenberg D.J. Lymphocyte studies in asymptomatic cigarette smokers. A comparison between lung and peripheral blood. Am. Rev. Respir. Dis. 116:1977;997-1005.
6. Darzynkiewicz Z., Sharpless T., Staiano-Coico L., Melamed M.R. Subcompartments of the G1 phase of cell cycle detected by flow cytometry. Proc. Natl. Acad. Sci. U.S.A. 77:1980;6696-6699.
7. Haynes W.F. Jr., Krstulovic V.J., Bell A.L. Jr. Smoking habit and incidence of respiratory tract infections in a group of adolescent males. Am. Rev. Respir. Dis. 93:1966;730-735.
8. Hecht S.S., Carmella S., Mori H., Hoffmann D. A study of tobacco carcinogenesis. XX. Role of catechol as a major cocarcinogen in the weakly acidic fraction of smoke condensate. J. Natl. Cancer. Inst. 66:1981;163-169.
9. Helin K. Regulation of cell proliferation by the E2F transcription factors. Curr. Opin. Genet. Dev. 8:1998;28-35.
10. Hermeking H., Rago C., Schuhmacher M., Li Q., Barrett J.F., Obaya A.J., O'Connell B.C., Mateyak M.K., Tan W., Kohlhumber F., Dang C.V., Sedivy J.M., Eick D., Vogelstein B., Kinzler K.W. Identification of CDK4 as a target of c-Myc. Proc. Natl. Acad. Sci. U.S.A. 97:2000;2229-2234.
11. Hoffmann D., Hecht S.S., Wynder E.L. Tumor promoters and cocarcinogens in tobacco carcinogenesis. Environ. Health Perspect. 50:1983;247-257.
12. Iritani B.M., Eisenman R.N. C-Myc enhances protein synthesis and cell size during B lymphocyte development. Proc. Natl. Acad. Sci. U.S.A. 96:1999;13180-13185.
13. Johnson J.D., Houchens D.P., Kluwe W.M., Craig D.K., Fisher G.L. Effects of mainstream and environmental tobacco smoke on the immune system in animals and humans: a review. Crit. Rev. Toxicol. 20:1990;369-395.
14. Kelly K., Cochran B.H., Stiles C.D., Leder P. Cell-specific regulation of the c-myc gene by lymphocyte mitogens and platelet-derived growth factor. Cell. 35:1983;603-610.
15. Kim S., Li Q., Dang C.V., Lee L.A. Induction of ribosomal genes and hepatocyte hypertrophy by adenovirus mediated expression of c-Myc in vivo. Proc. Natl. Acad. Sci. U.S.A. 97:2000;11198-11202.
16. Leone G., DeGregori J., Yan Z., Jakoi L., Ishida S., Williams R.S., Nevins J.R. E2F3 activity is regulated during the cell cycle and is required for the induction of S phase. Genes Dev. 12:1998;2120-2130.
17. Li Q., Geiselhart L., Mittler J.N., Mudzinski S.P., Lawrence D.A., Freed B.M. Inhibition of human T lymphoblast proliferation by hydroquinone. Toxicol. Appl. Pharmacol. 139:1996;317-323.
18. Li Q., Aubrey M.T., Christian T., Freed B.M. Differential inhibition of DNA synthesis in human T cells by the cigarette tar components hydroquinone and catechol. Fundam. Appl. Toxicol. 38:1997;158-165.
19. Li Q., Kasten-Jolly J., Yen Y., Freed B.M. Reversal of hydroquinone-mediated suppression of T cell proliferation by transfection of the M2 subunit of ribonucleotide reductase. Toxicol. Appl. Pharmacol. 150:1998;154-157.
20. Lucas J.J., Szepesi A., Domenico J., Takase K., Tordai A., Terada N., Gelfand E.W. Effects of iron-depletion on cell cycle progression in normal human T lymphocytes: selective inhibition of the appearance of the cyclin A-associated component of the p33cdk2 kinase. Blood. 86:1995;2268-2280.
21. McCue J.M., Link K.L., Eaton S.S., Freed B.M. Quenching of the tyrosyl radical in ribonucleotide reductase by cigarette tar. J. Immunol. 165:2000;6771-6775.
22. Modiano J.F., Kolp R., Lamb R.J., Nowell P.C. Protein kinase C regulates both production and secretion of interleukin 2. J. Biol. Chem. 266:1991;10552-10561.
23. Modiano J.F., Mayor J., Ball C., Chitko-McKown C.G., Sakata N., Domenico-Hahn J., Lucas J.J., Gelfand E.W. Quantitative and qualitative signals determine T-cell cycle entry and progression. Cell Immunol. 197:1999;19-29.
24. Neckers L.M. Regulation of transferrin receptor expression and control of cell growth. Pathobiology. 59:1991;11-18.
25. Nieman R.B., Fleming J., Coker R.J., Harris J.R., Mitchell D.M. The effect of cigarette smoking on the development of AIDS in HIV-1-seropositive individuals. Aids. 7:1993;705-710.
26. Oberg H.H., Lengl-Janssen B., Kabelitz D., Janssen O. Activation-induced T cell death: resistance or susceptibility correlate with cell surface fas ligand expression and T helper phenotype. Cell. Immunol. 181:1997;93-100.
27. Ouyang Y., Virasch N., Hao P., Aubrey M.T., Mukerjee N., Bierer B.E., Freed B.M. Suppression of human IL-1beta, IL-2, IFN-gamma, and TNF-alpha production by cigarette smoke extracts. J Allergy Clin. Immunol. 106:2000;280-287.
28. Persson H., Hennighausen L., Taub R., DeGrado W., Leder P. Antibodies to human c-myc oncogene product: evidence of an evolutionarily conserved protein induced during cell proliferation. Science. 225:1984;687-693.
29. Reed J.C., Nowell P.C., Hoover R.G. Regulation of c-myc mRNA levels in normal human lymphocytes by modulators of cell proliferation. Proc. Natl. Acad. Sci. U.S.A. 82:1985;4221-4224.
30. Sebbagh M., Renvoizé C., Hamelin J., Riché N., Bréard J. Caspase-3-mediated cleavage of ROCK I induces MLC phosphorylation and apoptotic membrane blebbing. Nat. Cell. Biol. 3:2001;346-352.
31. Sherr C.J. Cancer cell cycles. Science. 274:1996;1672-1677.
32. Sopori M. Effects of cigarette smoke on the immune system. Nature Rev. Immunol. 2:2002;372-377.
33. Squier M.K., Cohen J.J. Assays of apoptosis. Methods Mol. Biol. 144:2000;327-337.
34. US Department of Health, Education, and Welfare, 1979. A Report of the Surgeon General: Smoking and Health. US Government Printing Office, Washington, DC, p. 1136.
35. Weinberg R.A. The retinoblastoma protein and cell cycle control. Cell. 81:1995;323-330.
36. Wu K.J., Polack A., Dalla-Favera R. Coordinated regulation of iron-controlling genes, H-ferritin and IRP2, by c-Myc. Science. 283:1999;676-679.