Effect of cryoprotectants on the stability and aerosol performance of nebulized aviscumine, a 57-kDa protein

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 56, Issue 1, 2003, Pages 11-21

  Steckel, Hartwig ^a   Eskandar, Fadi ^a   Witthohn, Klaus ^b  

^a UNIVERSITY OF KIEL   (Germany)

^b VISCUM AG   (Germany)

Author keywords

Aviscumine; Cryoprotectants; Droplet size; Nebulization; Stability of proteins

Indexed keywords

AVISCUMINE; BUFFER; CRYOPROTECTIVE AGENT; EDETATE SODIUM; ISOTONIC SOLUTION; METHYL GROUP; OCTANOYL N METHYLGLUCAMIDE; POLYSORBATE 80; PROTEIN; TRICINE; TRIPOLYPHOSPHATE; TROMETAMOL; UNCLASSIFIED DRUG;

AEROSOL; ARTICLE; DRUG ACTIVITY; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG STABILITY; FREEZE DRYING; MOLECULAR WEIGHT; NEBULIZATION; NEBULIZER; PH; SURFACE TENSION; VISCOSITY;

EID: 0038015539     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0939-6411(03)00044-4     Document Type: Article

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