메뉴 건너뛰기




Volumn 10, Issue 3, 2003, Pages 161-167

Statins and plaque stability

Author keywords

cardiovascular; plaque stability; statins

Indexed keywords

ADENOSINE DIPHOSPHATE; ANTILIPEMIC AGENT; BLOOD CLOTTING FACTOR 10; BLOOD CLOTTING FACTOR 7; BLOOD CLOTTING FACTOR 7A; BLOOD CLOTTING FACTOR 9; FLUINDOSTATIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LOW DENSITY LIPOPROTEIN; PRAVASTATIN; SIMVASTATIN; SODIUM PROTON EXCHANGE PROTEIN; THROMBOPLASTIN; THROMBOXANE; CD40 LIGAND; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TISSUE FACTOR PATHWAY INHIBITOR;

EID: 0038010369     PISSN: 20474873     EISSN: 20474881     Source Type: Journal    
DOI: 10.1097/01.hjr.0000071771.88247.cf     Document Type: Article
Times cited : (6)

References (59)
  • 1
    • 0028240452 scopus 로고
    • Characterization of the relative thrombogenicity of atherosclerotic plaque components: Implications for consequences of plaque rupture
    • Fernandez-Ortiz A, Badimon JJ, Falk E, Fuster V, Meyer B, Mailhac A, et al. Characterization of the relative thrombogenicity of atherosclerotic plaque components: Implications for consequences of plaque rupture. J Am Coll Cardiol 1994; 23: 1562–1569.
    • (1994) J Am Coll Cardiol , vol.23 , pp. 1562-1569
    • Fernandez-Ortiz, A.1    Badimon, J.J.2    Falk, E.3    Fuster, V.4    Meyer, B.5    Mailhac, A.6
  • 2
    • 0031728460 scopus 로고    scopus 로고
    • Effects of lipids and lipoproteins on thrombosis and rheology
    • A comprehensive discussion on the influence of lipids and lipoproteins on thrombotic, fibrinolytic, and rheologic factors
    • Rosenson RS, Lowe GD. Effects of lipids and lipoproteins on thrombosis and rheology. Atherosclerosis 1998; 140: 271–280. A comprehensive discussion on the influence of lipids and lipoproteins on thrombotic, fibrinolytic, and rheologic factors.
    • (1998) Atherosclerosis , vol.140 , pp. 271-280
    • Rosenson, R.S.1    Lowe, G.D.2
  • 3
    • 0029926396 scopus 로고    scopus 로고
    • The crystal structure of the complex of blood coagulation factor VIIa with soluble tissue factor
    • Banner DW, D'Arcy A, Chene C, Winkler FK, Guha A, Konigsberg WH, et al. The crystal structure of the complex of blood coagulation factor VIIa with soluble tissue factor. Nature 1996; 380: 41–46.
    • (1996) Nature , vol.380 , pp. 41-46
    • Banner, D.W.1    D'Arcy, A.2    Chene, C.3    Winkler, F.K.4    Guha, A.5    Konigsberg, W.H.6
  • 4
    • 8044224017 scopus 로고    scopus 로고
    • Macrophages, smooth muscle cells, and tissue factor in unstable angina. Implications for cell-mediated thrombogenicity in acute coronary syndromes
    • Moreno PR, Bernardi VH, Lopez-Cuellar J, Murcia AM, Palacios IF, Gold HK, et al. Macrophages, smooth muscle cells, and tissue factor in unstable angina. Implications for cell-mediated thrombogenicity in acute coronary syndromes. Circulation 1996; 94: 3090–3097.
    • (1996) Circulation , vol.94 , pp. 3090-3097
    • Moreno, P.R.1    Bernardi, V.H.2    Lopez-Cuellar, J.3    Murcia, A.M.4    Palacios, I.F.5    Gold, H.K.6
  • 5
    • 0033551191 scopus 로고    scopus 로고
    • Local inhibition of tissue factor reduces the thrombogenicity of disrupted human atherosclerotic plaques: Effects of tissue factor pathway inhibitor on plaque thrombogenicity under flow conditions
    • A study elucidating the role of tissue factor as a thrombotic agent in plaque disruption
    • Badimon JJ, Lettino M, Toschi V, Fuster V, Berrozpe M, Chesebro JH, et al. Local inhibition of tissue factor reduces the thrombogenicity of disrupted human atherosclerotic plaques: Effects of tissue factor pathway inhibitor on plaque thrombogenicity under flow conditions. Circulation 1999; 99: 1780–1787. A study elucidating the role of tissue factor as a thrombotic agent in plaque disruption.
    • (1999) Circulation , vol.99 , pp. 1780-1787
    • Badimon, J.J.1    Lettino, M.2    Toschi, V.3    Fuster, V.4    Berrozpe, M.5    Chesebro, J.H.6
  • 6
    • 0033554455 scopus 로고    scopus 로고
    • Dietary lipid lowering reduces tissue factor expression in rabbit atheroma
    • A study done in rabbits testing the hypothesis that lipid lowering reduces tissue factor expression and activity. Diminished activity was associated with a decreased expression of CD40L and CD40, a trigger of tissue factor expression by macrophages in human atheroma
    • Aikawa M, Voglic SJ, Sugiyama S, Rabkin E, Taubman MB, Fallon JT, et al. Dietary lipid lowering reduces tissue factor expression in rabbit atheroma. Circulation 1999; 100: 1215–1222. A study done in rabbits testing the hypothesis that lipid lowering reduces tissue factor expression and activity. Diminished activity was associated with a decreased expression of CD40L and CD40, a trigger of tissue factor expression by macrophages in human atheroma.
    • (1999) Circulation , vol.100 , pp. 1215-1222
    • Aikawa, M.1    Voglic, S.J.2    Sugiyama, S.3    Rabkin, E.4    Taubman, M.B.5    Fallon, J.T.6
  • 7
    • 0031025656 scopus 로고    scopus 로고
    • Vastatins inhibit tissue factor in cultured human macrophages. A novel mechanism of protection against atherothrombosis
    • Colli S, Eligini S, Lalli M, Camera M, Paoletti R, Tremoli E. Vastatins inhibit tissue factor in cultured human macrophages. A novel mechanism of protection against atherothrombosis. Arterioscler Thromb Vasc Biol 1997; 17: 265–272.
    • (1997) Arterioscler Thromb Vasc Biol , vol.17 , pp. 265-272
    • Colli, S.1    Eligini, S.2    Lalli, M.3    Camera, M.4    Paoletti, R.5    Tremoli, E.6
  • 8
    • 0033786342 scopus 로고    scopus 로고
    • Statins and cardiovascular diseases: The multiple effects of lipid lowering therapy by statins
    • A study done in hypercholesterolaemic patients testing two hypotheses. The first was that a reduction of plasma lipid levels with statins reduces blood thrombogenicity and endothelial dysfunction. Second, was that the decreased thrombogenicity of blood and endothelium was associated with a decreased number of circulating soluble adhesion molecules
    • Rauch U, Osende JI, Chesebro JH, Fuster V, Vorchheimer DA, Harris K, et al. Statins and cardiovascular diseases: The multiple effects of lipid lowering therapy by statins. Atherosclerosis 2000; 153: 181–189. A study done in hypercholesterolaemic patients testing two hypotheses. The first was that a reduction of plasma lipid levels with statins reduces blood thrombogenicity and endothelial dysfunction. Second, was that the decreased thrombogenicity of blood and endothelium was associated with a decreased number of circulating soluble adhesion molecules.
    • (2000) Atherosclerosis , vol.153 , pp. 181-189
    • Rauch, U.1    Osende, J.I.2    Chesebro, J.H.3    Fuster, V.4    Vorchheimer, D.A.5    Harris, K.6
  • 9
    • 0034116167 scopus 로고    scopus 로고
    • Pravastatin: An anti-thrombotic effect independent of the cholesterol-lowering effect
    • A prospective six-month study of statin therapy illustrating that the diminished thrombogenicity provided by statin therapy was not proportional to the magnitude of LDL-C reduction. The study suggests that statins do more than diminish LDL-C and must have other affects causing the marked reduction in thrombogenicity
    • Dangas G, Smith DA, Unger AH, Shao JH, Meraj P, Fier C, et al. Pravastatin: An anti-thrombotic effect independent of the cholesterol-lowering effect. Thromb Haemost 2000; 83: 688–692. A prospective six-month study of statin therapy illustrating that the diminished thrombogenicity provided by statin therapy was not proportional to the magnitude of LDL-C reduction. The study suggests that statins do more than diminish LDL-C and must have other affects causing the marked reduction in thrombogenicity.
    • (2000) Thromb Haemost , vol.83 , pp. 688-692
    • Dangas, G.1    Smith, D.A.2    Unger, A.H.3    Shao, J.H.4    Meraj, P.5    Fier, C.6
  • 10
    • 0016398857 scopus 로고
    • Platelet function in hyperlipoproteinemia
    • Carvalho AC, Colman RW, Lees RS. Platelet function in hyperlipoproteinemia. N Engl J Med 1974; 290: 434–438.
    • (1974) N Engl J Med , vol.290 , pp. 434-438
    • Carvalho, A.C.1    Colman, R.W.2    Lees, R.S.3
  • 11
    • 0028049273 scopus 로고
    • LDLs increase the exposure of fibrinogen binding sites on platelets and secretion of dense granules
    • van Willigen G, Gorter G, Akkerman JW. LDLs increase the exposure of fibrinogen binding sites on platelets and secretion of dense granules. Arterioscler Thromb 1994; 14: 41–46.
    • (1994) Arterioscler Thromb , vol.14 , pp. 41-46
    • van Willigen, G.1    Gorter, G.2    Akkerman, J.W.3
  • 12
    • 0029319005 scopus 로고
    • Platelet cytosolic Ca2+ and membrane dynamics in patients with primary hypercholesterolaemia. Effects of pravastatin
    • Le Quan Sang KH, Levenson J, Megnien JL, Simon A, Devynck MA. Platelet cytosolic Ca2+ and membrane dynamics in patients with primary hypercholesterolaemia. Effects of pravastatin. Arterioscler Thromb Vasc Biol 1995; 15: 759–764.
    • (1995) Arterioscler Thromb Vasc Biol , vol.15 , pp. 759-764
    • Le Quan, S.K.H.1    Levenson, J.2    Megnien, J.L.3    Simon, A.4    Devynck, M.A.5
  • 15
    • 0000248914 scopus 로고    scopus 로고
    • Comparative effect of pravastatin and simvastatin on platelet-thrombus formation in hypercholesterolaemic coronary patients
    • Lacoste L, Lam JYT Comparative effect of pravastatin and simvastatin on platelet-thrombus formation in hypercholesterolaemic coronary patients. J Am Coll Cardiol 1996; 27: 413A.
    • (1996) J Am Coll Cardiol , vol.27 , pp. 413A
    • Lacoste, L.1    Lam, J.Y.T.2
  • 17
    • 0028909230 scopus 로고
    • Haemostatic factors and the risk of myocardial infarction or sudden death in patients with angina pectoris. European Concerted Action on Thrombosis and Disabilities Angina Pectoris Study Group
    • Thompson SG, Kienast J, Pyke SD, Haverkate F, van de Loo JC. Haemostatic factors and the risk of myocardial infarction or sudden death in patients with angina pectoris. European Concerted Action on Thrombosis and Disabilities Angina Pectoris Study Group. N Engl J Med 1995; 332: 635–641.
    • (1995) N Engl J Med , vol.332 , pp. 635-641
    • Thompson, S.G.1    Kienast, J.2    Pyke, S.D.3    Haverkate, F.4    van de Loo, J.C.5
  • 18
    • 0025878734 scopus 로고
    • Lovastatin therapy in hypercholesterolaemia: Effect on fibrinogen, hemorrheologic parameters, platelet activity, and red blood cell morphology
    • Beigel Y, Fuchs J, Snir M, Green P, Lurie Y, Djaldetti M. Lovastatin therapy in hypercholesterolaemia: Effect on fibrinogen, hemorrheologic parameters, platelet activity, and red blood cell morphology. J Clin Pharmacol 1991; 31: 512–517.
    • (1991) J Clin Pharmacol , vol.31 , pp. 512-517
    • Beigel, Y.1    Fuchs, J.2    Snir, M.3    Green, P.4    Lurie, Y.5    Djaldetti, M.6
  • 19
    • 0030967489 scopus 로고    scopus 로고
    • Comparison of one-year efficacy and safety of atorvastatin versus lovastatin in primary hypercholesterolaemia. Atorvastatin Study Group I
    • Davidson M, McKenney J, Stein E, Schrott H, Bakker-Arkema R, Fayyad R, et al. Comparison of one-year efficacy and safety of atorvastatin versus lovastatin in primary hypercholesterolaemia. Atorvastatin Study Group I. Am J Cardiol 1997; 79: 1475–1481.
    • (1997) Am J Cardiol , vol.79 , pp. 1475-1481
    • Davidson, M.1    McKenney, J.2    Stein, E.3    Schrott, H.4    Bakker-Arkema, R.5    Fayyad, R.6
  • 21
    • 0012600414 scopus 로고
    • Plasmin catalyzes binding of lipoprotein (a) to immobilized fibrinogen and fibrin
    • Harpel PC, Gordon BR, Parker TS. Plasmin catalyzes binding of lipoprotein (a) to immobilized fibrinogen and fibrin. Proc Natl Acad Sci USA 1989; 86: 3847–3851.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 3847-3851
    • Harpel, P.C.1    Gordon, B.R.2    Parker, T.S.3
  • 22
    • 0026695499 scopus 로고
    • Lovastatin alters blood rheology in primary hyperlipoproteinemia: Dependence on lipoprotein (a)
    • Koenig W, Hehr R, Ditschuneit HH, Kuhn K, Ernst E, Rosenthal J, et al. Lovastatin alters blood rheology in primary hyperlipoproteinemia: Dependence on lipoprotein (a)? J Clin Pharmacol 1992; 32: 539–545.
    • (1992) J Clin Pharmacol , vol.32 , pp. 539-545
    • Koenig, W.1    Hehr, R.2    Ditschuneit, H.H.3    Kuhn, K.4    Ernst, E.5    Rosenthal, J.6
  • 23
    • 0026597704 scopus 로고
    • Effects of long-term treatment with lovastatin on the clotting system and blood platelets
    • Mayer J, Eller T, Brauer P, Solleder EM, Schafer RM, Keller F, et al. Effects of long-term treatment with lovastatin on the clotting system and blood platelets. Ann Hematol 1992; 64: 196–201.
    • (1992) Ann Hematol , vol.64 , pp. 196-201
    • Mayer, J.1    Eller, T.2    Brauer, P.3    Solleder, E.M.4    Schafer, R.M.5    Keller, F.6
  • 24
    • 0031020585 scopus 로고    scopus 로고
    • Randomized placebo-controlled study of the effects of simvastatin on haemostatic variables, lipoproteins and free fatty acids. The Oxford Cholesterol Study Group
    • Mitropoulos KA, Armitage JM, Collins R, Meade TW, Reeves BE, Wallendszus KR, et al. Randomized placebo-controlled study of the effects of simvastatin on haemostatic variables, lipoproteins and free fatty acids. The Oxford Cholesterol Study Group. Eur Heart J 1997; 18: 235–241.
    • (1997) Eur Heart J , vol.18 , pp. 235-241
    • Mitropoulos, K.A.1    Armitage, J.M.2    Collins, R.3    Meade, T.W.4    Reeves, B.E.5    Wallendszus, K.R.6
  • 25
    • 0001544408 scopus 로고    scopus 로고
    • Vascular endothelium
    • In: Fuster V Ross R Topol ES (editors):. Philadelphia: Lippincott-Raven
    • DiCorleto P, Gimbrone MA. Vascular endothelium. In: Fuster V, Ross R, Topol ES (editors): Atherosclerosis and coronary artery disease. Vol. 1 Philadelphia: Lippincott-Raven; 1996 p. 387.
    • (1996) Atherosclerosis and coronary artery disease , vol.1 , pp. 387
    • DiCorleto, P.1    Gimbrone, M.A.2
  • 26
    • 0023028215 scopus 로고
    • Paradoxical vasoconstriction induced by acetylcholine in atherosclerotic coronary arteries
    • Ludmer PL, Selwyn AP, Shook TL, Wayne RR, Mudge GH, Alexander RW, et al. Paradoxical vasoconstriction induced by acetylcholine in atherosclerotic coronary arteries. N Engl J Med 1986; 315: 1046–1051.
    • (1986) N Engl J Med , vol.315 , pp. 1046-1051
    • Ludmer, P.L.1    Selwyn, A.P.2    Shook, T.L.3    Wayne, R.R.4    Mudge, G.H.5    Alexander, R.W.6
  • 27
    • 0028821643 scopus 로고
    • Oxidized low-density lipoprotein decreases the expression of endothelial nitric oxide synthase
    • Liao JK, Shin WS, Lee WY, Clark SL. Oxidized low-density lipoprotein decreases the expression of endothelial nitric oxide synthase. J Biol Chem 1995; 270: 319–324.
    • (1995) J Biol Chem , vol.270 , pp. 319-324
    • Liao, J.K.1    Shin, W.S.2    Lee, W.Y.3    Clark, S.L.4
  • 28
    • 0032584177 scopus 로고    scopus 로고
    • Up-regulation of endothelial nitric oxide synthase by HMG CoA reductase inhibitors
    • Laufs U, La Fata V, Plutzky J, Liao JK. Up-regulation of endothelial nitric oxide synthase by HMG CoA reductase inhibitors. Circulation 1998; 97: 1129–1135.
    • (1998) Circulation , vol.97 , pp. 1129-1135
    • Laufs, U.1    La Fata, V.2    Plutzky, J.3    Liao, J.K.4
  • 29
    • 18144435700 scopus 로고    scopus 로고
    • Pravastatin has cholesterol-lowering independent effects on the artery wall of atherosclerotic monkeys
    • Williams JK, Sukhova GK, Herrington DM, Libby P. Pravastatin has cholesterol-lowering independent effects on the artery wall of atherosclerotic monkeys. J Am Coll Cardiol 1998; 31: 684–691.
    • (1998) J Am Coll Cardiol , vol.31 , pp. 684-691
    • Williams, J.K.1    Sukhova, G.K.2    Herrington, D.M.3    Libby, P.4
  • 31
    • 0028283817 scopus 로고
    • Reduction in serum cholesterol with pravastatin improves endothelium-dependent coronary vasomotion in patients with hypercholesterolaemia
    • Egashira K, Hirooka Y, Kai H, Sugimachi M, Suzuki S, Inou T, et al. Reduction in serum cholesterol with pravastatin improves endothelium-dependent coronary vasomotion in patients with hypercholesterolaemia. Circulation 1994; 89: 2519–2524.
    • (1994) Circulation , vol.89 , pp. 2519-2524
    • Egashira, K.1    Hirooka, Y.2    Kai, H.3    Sugimachi, M.4    Suzuki, S.5    Inou, T.6
  • 32
    • 0031032831 scopus 로고    scopus 로고
    • Simvastatin, an HMG-coenzyme A reductase inhibitor, improves endothelial function within 1 month
    • O'Driscoll G, Green D, Taylor RR. Simvastatin, an HMG-coenzyme A reductase inhibitor, improves endothelial function within 1 month. Circulation 1997; 95: 1126–1131.
    • (1997) Circulation , vol.95 , pp. 1126-1131
    • O'Driscoll, G.1    Green, D.2    Taylor, R.R.3
  • 33
    • 0028204078 scopus 로고
    • Short-term cholesterol lowering decreases size and severity of perfusion abnormalities by positron emission tomography after dipyridamole in patients with coronary artery disease. A potential non-invasive marker of healing coronary endothelium
    • Gould KL, Martucci JP, Goldberg DI, Hess MJ, Edens RP, Latifi R, et al. Short-term cholesterol lowering decreases size and severity of perfusion abnormalities by positron emission tomography after dipyridamole in patients with coronary artery disease. A potential non-invasive marker of healing coronary endothelium. Circulation 1994; 89: 1530–1538.
    • (1994) Circulation , vol.89 , pp. 1530-1538
    • Gould, K.L.1    Martucci, J.P.2    Goldberg, D.I.3    Hess, M.J.4    Edens, R.P.5    Latifi, R.6
  • 34
    • 0029007253 scopus 로고
    • Improvement of myocardial perfusion by short-term fluvastatin therapy in coronary artery disease
    • Eichstadt HW, Eskotter H, Hoffman I, Amthauer HW, Weidinger G. Improvement of myocardial perfusion by short-term fluvastatin therapy in coronary artery disease. Am J Cardiol 1995; 76: 122A–125A.
    • (1995) Am J Cardiol , vol.76 , pp. 122A-125A
    • Eichstadt, H.W.1    Eskotter, H.2    Hoffman, I.3    Amthauer, H.W.4    Weidinger, G.5
  • 35
    • 0031018962 scopus 로고    scopus 로고
    • Effect of cholesterol reduction on myocardial ischemia in patients with coronary disease [see comments]
    • Andrews TC, Raby K, Barry J, Naimi CL, Allred E, Ganz P, et al. Effect of cholesterol reduction on myocardial ischemia in patients with coronary disease [see comments]. Circulation 1997; 95: 324–328.
    • (1997) Circulation , vol.95 , pp. 324-328
    • Andrews, T.C.1    Raby, K.2    Barry, J.3    Naimi, C.L.4    Allred, E.5    Ganz, P.6
  • 36
    • 0029778439 scopus 로고    scopus 로고
    • Reduction of transient myocardial ischemia with pravastatin in addition to the conventional treatment in patients with angina pectoris. REGRESS Study Group
    • van Boven AJ, Jukema JW, Zwinderman AH, Crijns HJ, Lie KI, Bruschke AV. Reduction of transient myocardial ischemia with pravastatin in addition to the conventional treatment in patients with angina pectoris. REGRESS Study Group. Circulation 1996; 94: 1503–1505.
    • (1996) Circulation , vol.94 , pp. 1503-1505
    • van Boven, A.J.1    Jukema, J.W.2    Zwinderman, A.H.3    Crijns, H.J.4    Lie, K.I.5    Bruschke, A.V.6
  • 37
  • 38
    • 0029054734 scopus 로고
    • Molecular bases of the acute coronary syndromes
    • A comprehensive review detailing the molecular mechanisms of acute coronary syndromes
    • Libby P. Molecular bases of the acute coronary syndromes. Circulation 1995; 91: 2844–2850. A comprehensive review detailing the molecular mechanisms of acute coronary syndromes.
    • (1995) Circulation , vol.91 , pp. 2844-2850
    • Libby, P.1
  • 39
    • 0033549388 scopus 로고    scopus 로고
    • Acute coronary syndromes: Biology
    • An extensive review of the biological phenomena causing acute coronary syndromes. The article explains the molecular mechanisms and correlates them with clinical syndromes. Future therapies with apoptotic and tissue factor inhibitors and the role of new imaging technologies are explored
    • Fuster V, Fayad ZA, Badimon JJ. Acute coronary syndromes: Biology. Lancet 1999; 353: 5–9. An extensive review of the biological phenomena causing acute coronary syndromes. The article explains the molecular mechanisms and correlates them with clinical syndromes. Future therapies with apoptotic and tissue factor inhibitors and the role of new imaging technologies are explored.
    • (1999) Lancet , vol.353 , pp. 5-9
    • Fuster, V.1    Fayad, Z.A.2    Badimon, J.J.3
  • 40
    • 0029084524 scopus 로고
    • Human monocyte-derived macrophages induce collagen breakdown in fibrous caps of atherosclerotic plaques. Potential role of matrix-degrading metalloproteinases and implications for plaque rupture
    • Shah PK, Falk E, Badimon JJ, Fernandez-Ortiz A, Mailhac A, Villareal-Levy G, et al. Human monocyte-derived macrophages induce collagen breakdown in fibrous caps of atherosclerotic plaques. Potential role of matrix-degrading metalloproteinases and implications for plaque rupture. Circulation 1995; 92: 1565–1569.
    • (1995) Circulation , vol.92 , pp. 1565-1569
    • Shah, P.K.1    Falk, E.2    Badimon, J.J.3    Fernandez-Ortiz, A.4    Mailhac, A.5    Villareal-Levy, G.6
  • 41
    • 0032560637 scopus 로고    scopus 로고
    • Lipid lowering by diet reduces matrix metalloproteinase activity and increases collagen content of rabbit atheroma: A potential mechanism of lesion stabilization
    • Aikawa M, Rabkin E, Okada Y, Voglic SJ, Clinton SK, Brinckerhoff CE, et al. Lipid lowering by diet reduces matrix metalloproteinase activity and increases collagen content of rabbit atheroma: A potential mechanism of lesion stabilization. Circulation 1998; 97: 2433–2444.
    • (1998) Circulation , vol.97 , pp. 2433-2444
    • Aikawa, M.1    Rabkin, E.2    Okada, Y.3    Voglic, S.J.4    Clinton, S.K.5    Brinckerhoff, C.E.6
  • 42
    • 0031048299 scopus 로고    scopus 로고
    • Oxidative modification of LDL and atherogenesis
    • Steinberg D. Oxidative modification of LDL and atherogenesis. Circulation 1997; 95: 1062–1072.
    • (1997) Circulation , vol.95 , pp. 1062-1072
    • Steinberg, D.1
  • 43
    • 0026589912 scopus 로고
    • Lovastatin inhibits low-density lipoprotein oxidation and alters its fluidity and uptake by macrophages: In vitro and in vivo studies
    • Aviram M, Dankner G, Cogan U, Hochgraf E, Brook JG. Lovastatin inhibits low-density lipoprotein oxidation and alters its fluidity and uptake by macrophages: In vitro and in vivo studies. Metabolism 1992; 41: 229–235.
    • (1992) Metabolism , vol.41 , pp. 229-235
    • Aviram, M.1    Dankner, G.2    Cogan, U.3    Hochgraf, E.4    Brook, J.G.5
  • 44
    • 0030886472 scopus 로고    scopus 로고
    • Effects of fluvastatin on leukocyte-endothelial cell adhesion in hypercholesterolaemic rats
    • Kimura M, Kurose I, Russell J, Granger DN. Effects of fluvastatin on leukocyte-endothelial cell adhesion in hypercholesterolaemic rats. Arterioscler Thromb Vasc Biol 1997; 17: 1521–1526.
    • (1997) Arterioscler Thromb Vasc Biol , vol.17 , pp. 1521-1526
    • Kimura, M.1    Kurose, I.2    Russell, J.3    Granger, D.N.4
  • 45
    • 0030838319 scopus 로고    scopus 로고
    • HMG-CoA reductase inhibitors decrease CD11b expression and CD11b-dependent adhesion of monocytes to endothelium and reduce increased adhesiveness of monocytes isolated from patients with hypercholesterolaemia
    • Weber C, Erl W, Weber KS, Weber PC. HMG-CoA reductase inhibitors decrease CD11b expression and CD11b-dependent adhesion of monocytes to endothelium and reduce increased adhesiveness of monocytes isolated from patients with hypercholesterolaemia. J Am Coll Cardiol 1997; 30: 1212–1217.
    • (1997) J Am Coll Cardiol , vol.30 , pp. 1212-1217
    • Weber, C.1    Erl, W.2    Weber, K.S.3    Weber, P.C.4
  • 46
    • 0031582209 scopus 로고    scopus 로고
    • Inhibition of proliferation of human smooth muscle cells by various HMG-CoA reductase inhibitors; comparison with other human cell types
    • Negre-Aminou P, van Vliet AK, van Erck M, van Thiel GC, van Leeuwen RE, Cohen LH. Inhibition of proliferation of human smooth muscle cells by various HMG-CoA reductase inhibitors; comparison with other human cell types. Biochim Biophys Acta 1997; 1345: 259–268.
    • (1997) Biochim Biophys Acta , vol.1345 , pp. 259-268
    • Negre-Aminou, P.1    van Vliet, A.K.2    van Erck, M.3    van Thiel, G.C.4    van Leeuwen, R.E.5    Cohen, L.H.6
  • 48
    • 0029809781 scopus 로고    scopus 로고
    • Magnetic resonance images lipid, fibrous, calcified, hemorrhagic, and thrombotic components of human atherosclerosis in vivo
    • Toussaint JF, LaMuraglia GM, Southern JF, Fuster V, Kantor HL. Magnetic resonance images lipid, fibrous, calcified, hemorrhagic, and thrombotic components of human atherosclerosis in vivo. Circulation 1996; 94: 932–938.
    • (1996) Circulation , vol.94 , pp. 932-938
    • Toussaint, J.F.1    LaMuraglia, G.M.2    Southern, J.F.3    Fuster, V.4    Kantor, H.L.5
  • 50
    • 0034737974 scopus 로고    scopus 로고
    • In vivo magnetic resonance evaluation of atherosclerotic plaques in the human thoracic aorta: A comparison with transesophageal echocardiography
    • An in vivo study using MR imaging evaluating atherosclerotic plaque size, extent and composition in human thoracic aorta. The study demonstrates the power and utility of MR imaging of atherosclerotic disease
    • Fayad ZA, Nahar T, Fallon JT, Goldman M, Aguinaldo JG, Badimon JJ, et al. In vivo magnetic resonance evaluation of atherosclerotic plaques in the human thoracic aorta: A comparison with transesophageal echocardiography. Circulation 2000; 101: 2503–2509. An in vivo study using MR imaging evaluating atherosclerotic plaque size, extent and composition in human thoracic aorta. The study demonstrates the power and utility of MR imaging of atherosclerotic disease.
    • (2000) Circulation , vol.101 , pp. 2503-2509
    • Fayad, Z.A.1    Nahar, T.2    Fallon, J.T.3    Goldman, M.4    Aguinaldo, J.G.5    Badimon, J.J.6
  • 51
    • 0034185484 scopus 로고    scopus 로고
    • Characterization of atherosclerotic plaques by magnetic resonance imaging
    • Fayad Z, Fuster V. Characterization of atherosclerotic plaques by magnetic resonance imaging. Annals of the New York Academy of Science 2000; 902: 173–186.
    • (2000) Annals of the New York Academy of Science , vol.902 , pp. 173-186
    • Fayad, Z.1    Fuster, V.2
  • 52
    • 0034255293 scopus 로고    scopus 로고
    • Non-invasive in vivo human coronary artery lumen and wall imaging using black-blood magnetic resonance imaging
    • An in vivo study using MR imaging demonstrated improved plaque characterization in human coronary arteries. MR imaging allows evaluation of plaque content and may become a useful diagnostic tool for detection of vulnerable lesions
    • Fayad ZA, Fuster V, Fallon JT, Jayasundera T, Worthley SG, Helft G, et al. Non-invasive in vivo human coronary artery lumen and wall imaging using black-blood magnetic resonance imaging. Circulation 2000; 102: 506–510. An in vivo study using MR imaging demonstrated improved plaque characterization in human coronary arteries. MR imaging allows evaluation of plaque content and may become a useful diagnostic tool for detection of vulnerable lesions.
    • (2000) Circulation , vol.102 , pp. 506-510
    • Fayad, Z.A.1    Fuster, V.2    Fallon, J.T.3    Jayasundera, T.4    Worthley, S.G.5    Helft, G.6
  • 54
    • 0028358762 scopus 로고
    • The relative importance of arterial remodeling compared with intimal hyperplasia in lumen re-narrowing after balloon angioplasty. A study in the normal rabbit and the hypercholesterolaemic Yucatan micropig
    • Post MJ, Borst C, Kuntz RE. The relative importance of arterial remodeling compared with intimal hyperplasia in lumen re-narrowing after balloon angioplasty. A study in the normal rabbit and the hypercholesterolaemic Yucatan micropig. Circulation 1994; 89: 2816–2821.
    • (1994) Circulation , vol.89 , pp. 2816-2821
    • Post, M.J.1    Borst, C.2    Kuntz, R.E.3
  • 55
    • 0023972981 scopus 로고
    • George Lyman Duff memorial lecture. Progression and regression of atherosclerotic lesions. Insights from lipid physical biochemistry
    • Small DM. George Lyman Duff memorial lecture. Progression and regression of atherosclerotic lesions. Insights from lipid physical biochemistry. Arteriosclerosis 1988; 8: 103–129.
    • (1988) Arteriosclerosis , vol.8 , pp. 103-129
    • Small, D.M.1
  • 56
    • 0032585608 scopus 로고    scopus 로고
    • Effect of HMG-CoA reductase inhibitors on coronary artery disease as assessed by electron-beam computed tomography
    • Callister TQ, Raggi P, Cooil B, Lippolis NJ, Russo DJ. Effect of HMG-CoA reductase inhibitors on coronary artery disease as assessed by electron-beam computed tomography. N Engl J Med 1998; 339: 1972–1978.
    • (1998) N Engl J Med , vol.339 , pp. 1972-1978
    • Callister, T.Q.1    Raggi, P.2    Cooil, B.3    Lippolis, N.J.4    Russo, D.J.5
  • 57
    • 0037016049 scopus 로고    scopus 로고
    • Lipid-lowering by simvastatin induces regression of human atherosclerotic lesions: 2 years follow-up by high resolution noninvasive MRI
    • Corti R, Fuster V, Fayad ZA, Worthley SG, Helft G, Smith D, et al. Lipid-lowering by simvastatin induces regression of human atherosclerotic lesions: 2 years follow-up by high resolution noninvasive MRI. Circulation 2002; 106: 2884–2887.
    • (2002) Circulation , vol.106 , pp. 2884-2887
    • Corti, R.1    Fuster, V.2    Fayad, Z.A.3    Worthley, S.G.4    Helft, G.5    Smith, D.6
  • 58
    • 0032572043 scopus 로고    scopus 로고
    • Anti-atherothrombotic properties of statins: Implications for cardiovascular event reduction
    • Rosenson RS, Tangney CC. Anti-atherothrombotic properties of statins: Implications for cardiovascular event reduction. JAMA 1998; 279: 1643–1650.
    • (1998) JAMA , vol.279 , pp. 1643-1650
    • Rosenson, R.S.1    Tangney, C.C.2
  • 59
    • 0000306390 scopus 로고    scopus 로고
    • Statins do more than just lower cholesterol
    • Vaughan CJ, Murphy MB, Buckley BM. Statins do more than just lower cholesterol. Lancet 1996; 348: 1079–1082.
    • (1996) Lancet , vol.348 , pp. 1079-1082
    • Vaughan, C.J.1    Murphy, M.B.2    Buckley, B.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.