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Bioorganic Chemistry

Volumn 31, Issue 3, 2003, Pages 237-247

HPLC and mass spectrometry analysis of the enzymatic hydrolysis of anti-HIV pronucleotide diastereomers

(4) Mesplet, Nathalie a Saito, Yoshio a Morin, Philippe a Agrofoglio, Luigi A a

a UNIVERSITÉ D'ORLÉANS (France)

Author keywords

Cellulose chiral column; HIV; Mass spectrometry; Phosphoramidates; Pig liver esterase; Prodrugs

Indexed keywords

ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; ESTERASE; LAMIVUDINE; LIVER ENZYME; NUCLEOTIDE DERIVATIVE; PHOSPHORAMIDIC ACID DERIVATIVE; POLYSACCHARIDE; PRODRUG; SO 324; STAVUDINE; UNCLASSIFIED DRUG; ZIDOVUDINE;

ARTICLE; CATALYSIS; CHIRALITY; DIASTEREOISOMER; DRUG HYDROLYSIS; ENZYME SPECIFICITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS COMMUNICATION; MASS SPECTROMETRY; PRIORITY JOURNAL; SWINE;

SUS SCROFA;

EID: 0038010288 PISSN: 00452068 EISSN: None Source Type: Journal
DOI: 10.1016/S0045-2068(03)00035-X Document Type: Article

Times cited : (12)

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