-
1
-
-
15644363454
-
Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors
-
Hirota S, Isozaki K, Moriyama Y, et al.: Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors. Science 1998, 279:577-580.
-
(1998)
Science
, vol.279
, pp. 577-580
-
-
Hirota, S.1
Isozaki, K.2
Moriyama, Y.3
-
2
-
-
0036301722
-
Diagnosis of gastrointestinal stromal tumors: A consensus approach
-
Fletcher CD, Berman JJ, Corless C, et al.: Diagnosis of gastrointestinal stromal tumors: a consensus approach. Hum Pathol 2002, 33:459-465.
-
(2002)
Hum. Pathol.
, vol.33
, pp. 459-465
-
-
Fletcher, C.D.1
Berman, J.J.2
Corless, C.3
-
3
-
-
0036232194
-
Gastrointestinal stromal tumour of the oesophagus: Significance of immunohistochemical and genetic analyses of the c-kit gene
-
Iijima S, Maesawa C, Sato N, et al.: Gastrointestinal stromal tumour of the oesophagus: significance of immunohistochemical and genetic analyses of the c-kit gene. Eur J Gastroenterol Hepatol 2002, 14:445-448.
-
(2002)
Eur. J. Gastroenterol. Hepatol.
, vol.14
, pp. 445-448
-
-
Iijima, S.1
Maesawa, C.2
Sato, N.3
-
4
-
-
0034766329
-
Gastrointestinal stromal tumors in the appendix: A clinicopathologic and immunohistochemical study of four cases
-
Miettinen M, Sobin LH: Gastrointestinal stromal tumors in the appendix: a clinicopathologic and immunohistochemical study of four cases. Am J Surg Pathol 2001, 25:1433-1437.
-
(2001)
Am. J. Surg. Pathol.
, vol.25
, pp. 1433-1437
-
-
Miettinen, M.1
Sobin, L.H.2
-
5
-
-
0034880736
-
Gastrointestinal stromal tumor of the duodenal ampulla: Report of a case
-
Takahashi Y, Noguchi T, Takeno S, et al.: Gastrointestinal stromal tumor of the duodenal ampulla: report of a case. Surg Today 2001, 31:722-726.
-
(2001)
Surg. Today
, vol.31
, pp. 722-726
-
-
Takahashi, Y.1
Noguchi, T.2
Takeno, S.3
-
6
-
-
0034883994
-
Gastrointestinal stromal tumors, intramural leiomyomas, and leiomyosarcomas in the rectum and anus: A clinicopathologic, immunohistochemical, and molecular genetic study of 144 cases
-
Miettinen M, Furlong M, Sarlomo-Rikala M, et al.: Gastrointestinal stromal tumors, intramural leiomyomas, and leiomyosarcomas in the rectum and anus: a clinicopathologic, immunohistochemical, and molecular genetic study of 144 cases. Am J Surg Pathol 2001, 25:1121-1133.
-
(2001)
Am. J. Surg. Pathol.
, vol.25
, pp. 1121-1133
-
-
Miettinen, M.1
Furlong, M.2
Sarlomo-Rikala, M.3
-
7
-
-
0034889848
-
Gastrointestinal stromal tumors and KIT-positive mesenchymal cells in the omentum
-
Sakurai S, HishimaT, Takazawa Y, et al.: Gastrointestinal stromal tumors and KIT-positive mesenchymal cells in the omentum. Pathol Int 2001, 51:524-531.
-
(2001)
Pathol. Int.
, vol.51
, pp. 524-531
-
-
Sakurai, S.1
Hishima, T.2
Takazawa, Y.3
-
8
-
-
0034880198
-
Gastrointestinal stromal tumor of the lesser omentum: Report of a case
-
Fukuda H, Suwa T, Kimura F, et al.: Gastrointestinal stromal tumor of the lesser omentum: report of a case. Surg Today 2001, 31:715-718.
-
(2001)
Surg. Today
, vol.31
, pp. 715-718
-
-
Fukuda, H.1
Suwa, T.2
Kimura, F.3
-
9
-
-
0036227930
-
Cutaneous metastases from a gastrointestinal stromal tumor of the stomach: Review of literature
-
Shabahang M, Livingstone AS: Cutaneous metastases from a gastrointestinal stromal tumor of the stomach: review of literature. Dig Surg 2002, 19:64-65.
-
(2002)
Dig. Surg.
, vol.19
, pp. 64-65
-
-
Shabahang, M.1
Livingstone, A.S.2
-
10
-
-
0031848146
-
Familial gastrointestinal stromal tumors with germline mutation of the KIT gene
-
Nishida T, Hirota S, Taniguchi M, et al.: Familial gastrointestinal stromal tumors with germline mutation of the KIT gene. Nat Genet 1998, 19:323-324.
-
(1998)
Nat. Genet.
, vol.19
, pp. 323-324
-
-
Nishida, T.1
Hirota, S.2
Taniguchi, M.3
-
11
-
-
0035174752
-
Familial gastrointestinal stromal tumor with hyperpigmentation: Association with a germline mutation of the c-kit gene
-
Maeyama H, Hidaka E, Ota H, et al.: Familial gastrointestinal stromal tumor with hyperpigmentation: association with a germline mutation of the c-kit gene. Gastroenterology 2001, 120:210-215.
-
(2001)
Gastroenterology
, vol.120
, pp. 210-215
-
-
Maeyama, H.1
Hidaka, E.2
Ota, H.3
-
12
-
-
0033064974
-
Gastric stromal sarcoma, pulmonary chondroma, and extra-adrenal paraganglioma Carney Triad): Natural history, adrenocortical component, and possible familial occurrence
-
Carney JA: Gastric stromal sarcoma, pulmonary chondroma, and extra-adrenal paraganglioma Carney Triad): natural history, adrenocortical component, and possible familial occurrence. Mayo Clin Proc 1999, 74:543-552.
-
(1999)
Mayo Clin. Proc.
, vol.74
, pp. 543-552
-
-
Carney, J.A.1
-
13
-
-
0036657064
-
Epithelioid gastrointestinal stromal tumor of the stomach with liver metastases in a 12-year-old girl: Aspiration cytology and molecular study
-
Li P, Wei J, West AB, Perle M, et al.: Epithelioid gastrointestinal stromal tumor of the stomach with liver metastases in a 12-year-old girl: aspiration cytology and molecular study. Pediatr Dev Pathol 2002, 5:386-384.
-
(2002)
Pediatr. Dev. Pathol.
, vol.5
, pp. 384-386
-
-
Li, P.1
Wei, J.2
West, A.B.3
Perle, M.4
-
14
-
-
0034933716
-
Gastrointestinal autonomic nerve tumor: Immunohistochemical and molecular identity with gastrointestinal stromal tumor
-
Lee JR, Joshi V, Griffin JW Jr, et al.: Gastrointestinal autonomic nerve tumor: immunohistochemical and molecular identity with gastrointestinal stromal tumor. Am J Surg Pathol 2001, 25:979-987.
-
(2001)
Am. J. Surg. Pathol.
, vol.25
, pp. 979-987
-
-
Lee, J.R.1
Joshi, V.2
Griffin Jr., J.W.3
-
15
-
-
0036301863
-
Evaluation of malignancy and prognosis of gastrointestinal stromal tumors: A review
-
L HLS
-
Miettinen M, El-Rifai W, L HLS, Lasota J: Evaluation of malignancy and prognosis of gastrointestinal stromal tumors: a review. Hum Pathol 2002, 33:478-483.
-
(2002)
Hum. Pathol.
, vol.33
, pp. 478-483
-
-
Miettinen, M.1
El-Rifai, W.2
Lasota, J.3
-
16
-
-
0034049784
-
Predicting metastatic risk of gastrointestinal stromal tumors: Role of cell proliferation and cell cycle regulatory proteins
-
Panizo-Santos A, Sola I, Vega F, et al.: Predicting metastatic risk of gastrointestinal stromal tumors: role of cell proliferation and cell cycle regulatory proteins. Int J Surg Pathol 2000, 8:133-144.
-
(2000)
Int. J. Surg. Pathol.
, vol.8
, pp. 133-144
-
-
Panizo-Santos, A.1
Sola, I.2
Vega, F.3
-
17
-
-
0032953812
-
Mutations in exon 11 of c-Kit occur preferentially in malignant versus benign gastrointestinal stromal tumors and do not occur in leiomyomas or leiomyosarcomas
-
Lasota J, Jasinski M, Sarlomo-Rikala M, Miettinen M: Mutations in exon 11 of c-Kit occur preferentially in malignant versus benign gastrointestinal stromal tumors and do not occur in leiomyomas or leiomyosarcomas. Am J Pathol 1999, 154:53-60.
-
(1999)
Am. J. Pathol.
, vol.154
, pp. 53-60
-
-
Lasota, J.1
Jasinski, M.2
Sarlomo-Rikala, M.3
Miettinen, M.4
-
18
-
-
0035890740
-
Activation is a ubiquitous feature of gastrointestinal stromal tumors
-
Rubin B, Singer S, Tsao C, et al.: Activation is a ubiquitous feature of gastrointestinal stromal tumors. Cancer Res 2001, 61:8118-8121.
-
(2001)
Cancer Res.
, vol.61
, pp. 8118-8121
-
-
Rubin, B.1
Singer, S.2
Tsao, C.3
-
19
-
-
0036092268
-
KIT Mutations are common in incidental gastrointestinal stromal tumors one centimeter or less in size
-
Coreless CL, McGreevey L, Haley A, et al.: KIT Mutations are common in incidental gastrointestinal stromal tumors one centimeter or less in size. Am J Pathol 2002, 160:1567-1572.
-
(2002)
Am. J. Pathol.
, vol.160
, pp. 1567-1572
-
-
Coreless, C.L.1
McGreevey, L.2
Haley, A.3
-
20
-
-
0037087531
-
Inhibition of KIT tyrosine kinase activity: A novel molecular approach to the treatment of KIT-positive malignancies
-
Heinrich M, Blanke C, Druker B, Corless C: Inhibition of KIT tyrosine kinase activity: a novel molecular approach to the treatment of KIT-positive malignancies. J Clin Oncol 2002, 20:1692-1703.
-
(2002)
J. Clin. Oncol.
, vol.20
, pp. 1692-1703
-
-
Heinrich, M.1
Blanke, C.2
Druker, B.3
Corless, C.4
-
21
-
-
0036303804
-
Biology and genetic aspects of gastrointestinal stromal tumors: KIT activation and cytogenetic alterations
-
Heinrich M, Rubin B, Longley B, Fletcher J: Biology and genetic aspects of gastrointestinal stromal tumors: KIT activation and cytogenetic alterations. Hum Pathol 2002, 33:484-495.
-
(2002)
Hum. Pathol.
, vol.33
, pp. 484-495
-
-
Heinrich, M.1
Rubin, B.2
Longley, B.3
Fletcher, J.4
-
22
-
-
0036141147
-
The complexity of KIT gene mutations and chromosome rearrangements and their clinical correlation in gastrointestinal stromal (pacemaker cell) tumors
-
Andersson J, Sjogren H, Meis-Kindblom JM, et al.: The complexity of KIT gene mutations and chromosome rearrangements and their clinical correlation in gastrointestinal stromal (pacemaker cell) tumors. Am J Pathol 2002, 160:15-22.
-
(2002)
Am. J. Pathol.
, vol.160
, pp. 15-22
-
-
Andersson, J.1
Sjogren, H.2
Meis-Kindblom, J.M.3
-
23
-
-
0242670019
-
PDGFRA activating mutations in gastrointestinal stromal tumors
-
Heinrich MC, Coreless CL, Duensing A, et al.: PDGFRA activating mutations in gastrointestinal stromal tumors. Science 2003, 299:708-10.
-
(2003)
Science
, vol.299
, pp. 708-710
-
-
Heinrich, M.C.1
Coreless, C.L.2
Duensing, A.3
-
24
-
-
0036329780
-
Gastrointestinal stromal tumor: Consistent CD117 immunostaining for diagnosis, and prognostic classification based on tumor size and MIB-1 grade
-
Hasegawa T, Matsumo Y, Hirohashi S: Gastrointestinal stromal tumor: consistent CD117 immunostaining for diagnosis, and prognostic classification based on tumor size and MIB-1 grade. Hum Pathol 2002, 33:669-676.
-
(2002)
Hum. Pathol.
, vol.33
, pp. 669-676
-
-
Hasegawa, T.1
Matsumo, Y.2
Hirohashi, S.3
-
25
-
-
0037106370
-
Prognostic value of KIT mutation type, mitotic activity, and histologic subtype in gastrointestinal stromal tumors
-
Singer S, Rubin B, Lux M, et al.: Prognostic value of KIT mutation type, mitotic activity, and histologic subtype in gastrointestinal stromal tumors. J Clin Oncol 2002, 20:3898-3905.
-
(2002)
J. Clin. Oncol.
, vol.20
, pp. 3898-3905
-
-
Singer, S.1
Rubin, B.2
Lux, M.3
-
26
-
-
0036242273
-
Biological and clinical significance of cytogenetic abnormalities in low-risk and high-risk gastrointestinal stromal tumors
-
Gunawan B, Bergmann F, Hoer J, et al.: Biological and clinical significance of cytogenetic abnormalities in low-risk and high-risk gastrointestinal stromal tumors. Hum Pathol 2002, 33:316-321.
-
(2002)
Hum. Pathol.
, vol.33
, pp. 316-321
-
-
Gunawan, B.1
Bergmann, F.2
Hoer, J.3
-
27
-
-
0034660868
-
DNA sequence copy number changes in gastrointestinal stromal tumors: Tumor progression and prognostic significance
-
El-Rifai W, Sarlomo-Rikala M, Andersson LC, et al.: DNA sequence copy number changes in gastrointestinal stromal tumors: tumor progression and prognostic significance. Cancer Res 2000, 60:3899-903.
-
(2000)
Cancer Res.
, vol.60
, pp. 3899-3903
-
-
El-Rifai, W.1
Sarlomo-Rikala, M.2
Andersson, L.C.3
-
28
-
-
0036049018
-
Contrast of response to dacarbazine, mitomycin, doxorubicin, and cisplatin (DMAP) plus GM-CSF between patients with advanced malignant gastrointestinal stromal tumors and patients with other advanced leiomyosarcomas
-
Edmonson JH, Marks RS, Buckner JC, Mahoney MR: Contrast of response to dacarbazine, mitomycin, doxorubicin, and cisplatin (DMAP) plus GM-CSF between patients with advanced malignant gastrointestinal stromal tumors and patients with other advanced leiomyosarcomas. Cancer Invest 2002, 20:605-612.
-
(2002)
Cancer Invest.
, vol.20
, pp. 605-612
-
-
Edmonson, J.H.1
Marks, R.S.2
Buckner, J.C.3
Mahoney, M.R.4
-
29
-
-
0036305274
-
Clinical management of gastrointestinal stromal tumors: Before and after STI-571
-
Dematteo RP, Heinrich MC, El-Rifai WM, Demetri G: Clinical management of gastrointestinal stromal tumors: before and after STI-571. Hum Pathol 2002, 33:466-477.
-
(2002)
Hum. Pathol.
, vol.33
, pp. 466-477
-
-
Dematteo, R.P.1
Heinrich, M.C.2
El-Rifai, W.M.3
Demetri, G.4
-
30
-
-
0035960428
-
Safety and efficacy of imatinib (STI571) in metastatic gastrointestinal stromal tumours: A phase I study
-
van Oosterom A, Judson I, Verweij J, et al.: Safety and efficacy of imatinib (STI571) in metastatic gastrointestinal stromal tumours: a phase I study. Lancet 2001, 358:1421-1423.
-
(2001)
Lancet
, vol.358
, pp. 1421-1423
-
-
van Oosterom, A.1
Judson, I.2
Verweij, J.3
-
31
-
-
0037103424
-
Efficacy and safety of imatinib mesylate in advanced gastrointestinal stromal tumors
-
Demetri G, vonMehren M, Blanke C, et al.: Efficacy and safety of imatinib mesylate in advanced gastrointestinal stromal tumors. N Engl J Med 2002, 347:472-480.
-
(2002)
N. Engl. J. Med.
, vol.347
, pp. 472-480
-
-
Demetri, G.1
vonMehren, M.2
Blanke, C.3
-
32
-
-
0030031766
-
Inhibition of the Abl protein-tyrosine kinase in vitro and in vivo by a 2-phenylaminopyrimidine derivative
-
Buchdunger E, Zimmermann J, Mett H, et al.: Inhibition of the Abl protein-tyrosine kinase in vitro and in vivo by a 2-phenylaminopyrimidine derivative. Cancer Res 1996, 56:100-104.
-
(1996)
Cancer Res.
, vol.56
, pp. 100-104
-
-
Buchdunger, E.1
Zimmermann, J.2
Mett, H.3
-
33
-
-
0033816156
-
Abl protein-tyrosine kinase inhibitor STI571 inhibits in vitro signal transduction mediated by c-kit and platelet-derived growth factor receptors
-
Buchdunger E, Cioffi CL, Law N, et al.: Abl protein-tyrosine kinase inhibitor STI571 inhibits in vitro signal transduction mediated by c-kit and platelet-derived growth factor receptors. J Pharmacol Exp Ther 2000, 295:139-145.
-
(2000)
J. Pharmacol. Exp. Ther.
, vol.295
, pp. 139-145
-
-
Buchdunger, E.1
Cioffi, C.L.2
Law, N.3
-
34
-
-
0000244046
-
Evaluation of the safety and efficacy of an oral molecularly-targeted therapy, STI571, in patients (pts) with unresectable or metastatic gastrointestinal Stromal Tumors (GISTS) expressing c-kit (CD117)
-
[abstract]
-
Blanke C, vonMehren M, Joensu H, et al.: Evaluation of the safety and efficacy of an oral molecularly-targeted therapy, STI571, in patients (pts) with unresectable or metastatic gastrointestinal Stromal Tumors (GISTS) expressing c-kit (CD117) [abstract]. Proc ASCO. 2001, 20:1.
-
(2001)
Proc. ASCO
, vol.20
, pp. 1
-
-
Blanke, C.1
vonMehren, M.2
Joensu, H.3
-
35
-
-
0242691170
-
Phase III dose-randomized study of imatinib mesylate (IM) for GIST: Intergroup S0033 early results
-
[abstract]
-
Benjamin R, Rankin C, Fletcher C, et al.: Phase III dose-randomized study of imatinib mesylate (IM) for GIST: Intergroup S0033 early results [abstract]. Proc ASCO 2003.
-
(2003)
Proc. ASCO
-
-
Benjamin, R.1
Rankin, C.2
Fletcher, C.3
-
36
-
-
0242522370
-
Early efficacy comparison of two doses of imatinib for the treatment of advanced Gastrointestinal Stromal Tumors (GIST): Interim results of a randomized phase III trial form the EORTC-STBSG, ISG and AGITG
-
[abstract]
-
Verweij J, Casali P, Zalcgerg J, et al.: Early efficacy comparison of two doses of imatinib for the treatment of advanced Gastrointestinal Stromal Tumors (GIST): interim results of a randomized phase III trial form the EORTC-STBSG, ISG and AGITG [abstract]: Proc ASCO 2003.
-
(2003)
Proc. ASCO
-
-
Verweij, J.1
Casali, P.2
Zalcgerg, J.3
-
37
-
-
0346210265
-
Prognostic factors of toxicity and efficacy in patients with Gastro-Intestinal Stromal Tumors (GIST) treated with imatinib: A study of the EORTC-STBSG, ISG and AGITG
-
[abstract]
-
Van Glabbeke M, Verweij J, Casali P, et al.: Prognostic factors of toxicity and efficacy in patients with Gastro-Intestinal Stromal Tumors (GIST) treated with imatinib: a study of the EORTC-STBSG, ISG and AGITG [abstract]. Proc ASCO 2003.
-
(2003)
Proc. ASCO
-
-
Van Glabbeke, M.1
Verweij, J.2
Casali, P.3
-
38
-
-
0347471424
-
Population pharmacokinetic (PK) analysis and PK-pharmacodynamic (PD) correlations in phase I/II trial of imatinib in gastrointestinal stromal tumours (GIST) conducted by the European Organisation for Research and Treatment of Cancer Soft Tissue and Bone Sarcoma Group
-
[abstract]
-
Judson I, Donato Di Paloa E, Verweij J, et al.: Population pharmacokinetic (PK) analysis and PK-pharmacodynamic (PD) correlations in phase I/II trial of imatinib in gastrointestinal stromal tumours (GIST) conducted by the European Organisation for Research and Treatment of Cancer Soft Tissue and Bone Sarcoma Group [abstract]. Proc ASCO 2003.
-
(2003)
Proc. ASCO
-
-
Judson, I.1
Donato Di Paloa, E.2
Verweij, J.3
-
39
-
-
0242607132
-
Mechanisms of resistance to imatinib mesylate (IM) in advanced gastointestinal stromal tumors (GISTs)
-
[abstract]
-
Heinrich M, Corless CL, Demetri G, et al.: Mechanisms of resistance to imatinib mesylate (IM) in advanced gastointestinal stromal tumors (GISTs) [abstract] Proc ASCO 2003.
-
(2003)
Proc. ASCO
-
-
Heinrich, M.1
Corless, C.L.2
Demetri, G.3
-
40
-
-
0003222972
-
High incidence of durable responses induced by Imatinib mesylate (Gleevec™) in patients with unresectable and metastatic gastrointestinal stromal tumors (GISTs)
-
[abstract]
-
von Mehren M, Blanke C, Joensuu H, et al.: High incidence of durable responses induced by Imatinib mesylate (Gleevec™) in patients with unresectable and metastatic gastrointestinal stromal tumors (GISTs) [abstract]. Proc ASCO 2002, 21:1608.
-
(2002)
Proc. ASCO
, vol.21
, pp. 1608
-
-
von Mehren, M.1
Blanke, C.2
Joensuu, H.3
-
41
-
-
0003280395
-
Update of imatinib (STI571, Glivec) phase I study in gastrointestinal stromal tumors (GISTs)
-
[abstract]
-
van Oosterom A, Judson I, Verweij J, et al.: Update of imatinib (STI571, Glivec) phase I study in gastrointestinal stromal tumors (GISTs) [abstract]. Proc ASCO 2002, 21:327.
-
(2002)
Proc. ASCO
, vol.21
, pp. 327
-
-
van Oosterom, A.1
Judson, I.2
Verweij, J.3
-
42
-
-
0037254419
-
Imatinib alone and in combination for chronic myeloid leukemia
-
Druker BJ: Imatinib alone and in combination for chronic myeloid leukemia. Semin Hematol 2003, 40:50-58.
-
(2003)
Semin. Hematol.
, vol.40
, pp. 50-58
-
-
Druker, B.J.1
-
43
-
-
0242691165
-
Mechanisms of resistance to imatinib mesylate (IM) in advanced gastrointestinal stromal tumor (GIST)
-
[abstract]
-
Fletcher J, Corless C, Dimitrijevic S, et al.: Mechanisms of resistance to imatinib mesylate (IM) in advanced gastrointestinal stromal tumor (GIST) [abstract] Proc ASCO 2003.
-
(2003)
Proc. ASCO
-
-
Fletcher, J.1
Corless, C.2
Dimitrijevic, S.3
-
44
-
-
3142623000
-
Identification of response markers and the moclecular mechanism of action
-
[abstract]
-
Frolov A, Chawan S, Pan ZZ, et al.: Identification of response markers and the moclecular mechanism of action [abstract]. Proc AACR 2003.
-
(2003)
Proc. AACR
-
-
Frolov, A.1
Chawan, S.2
Pan, Z.Z.3
-
45
-
-
0242438809
-
Clinical activity and tolerability of the multi-targeted tyrosine kinase inhibitor SU11248 in patients (pts) with metastatic gastrointestinal stromal tumor (GIST) refractory to imatinib mesylate
-
[abstract]
-
Demetri G, George S, Heinrich MC, et al.: Clinical activity and tolerability of the multi-targeted tyrosine kinase inhibitor SU11248 in patients (pts) with metastatic gastrointestinal stromal tumor (GIST) refractory to imatinib mesylate [abstract]. Proc ASCO 2003.
-
(2003)
Proc. ASCO
-
-
Demetri, G.1
George, S.2
Heinrich, M.C.3
|