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Volumn 34, Issue 5, 2003, Pages 1048-1063

Antiangiogenic tumor therapy

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOGENESIS INHIBITOR; ANGIOSTATIN; ANTINEOPLASTIC AGENT; BASIC FIBROBLAST GROWTH FACTOR; CILENGITIDE; CISPLATIN; CYCLOPHOSPHAMIDE; CYTOTOXIC AGENT; DOCETAXEL; DOXORUBICIN; ENDOSTATIN; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; FLUOROURACIL; FUMAGILLOL CHLOROACETYLCARBAMATE; GEFITINIB; IMATINIB; MATRIX METALLOPROTEINASE; MATRIX METALLOPROTEINASE INHIBITOR; N ACETYLCOLCHINOL PHOSPHATE; ONCOPROTEIN; PLATELET DERIVED GROWTH FACTOR B; TANOMASTAT; TEMOZOLOMIDE; THALIDOMIDE; TRANSFORMING GROWTH FACTOR ALPHA; TRASTUZUMAB; UNCLASSIFIED DRUG; UNINDEXED DRUG; VASCULOTROPIN; VASCULOTROPIN RECEPTOR 2;

EID: 0037990077     PISSN: 07366205     EISSN: None     Source Type: Journal    
DOI: 10.2144/03345dd01     Document Type: Note
Times cited : (14)

References (100)
  • 1
    • 0034076189 scopus 로고    scopus 로고
    • Mechanisms of angiogenesis and arteriogenesis
    • Carmeliet, P. 2000. Mechanisms of angiogenesis and arteriogenesis. Nat. Med. 6:389-395.
    • (2000) Nat. Med. , vol.6 , pp. 389-395
    • Carmeliet, P.1
  • 2
    • 85013312416 scopus 로고
    • Tumor angiogenesis: Therapeutic implications
    • Folkman, J. 1971. Tumor angiogenesis: therapeutic implications. N. Engl. J. Med. 285:1182-1186.
    • (1971) N. Engl. J. Med. , vol.285 , pp. 1182-1186
    • Folkman, J.1
  • 3
    • 0024517730 scopus 로고
    • Treatment of pulmonary hemangiomatosis with recombinant interferon α-2a
    • White, C.W., H.M. Sondheimer, E.C. Crouch, H. Wilson, and L.L. Fan. 1989. Treatment of pulmonary hemangiomatosis with recombinant interferon α-2a. N. Engl. J. Med. 320:1197-1200.
    • (1989) N. Engl. J. Med. , vol.320 , pp. 1197-1200
    • White, C.W.1    Sondheimer, H.M.2    Crouch, E.C.3    Wilson, H.4    Fan, L.L.5
  • 5
    • 0028929803 scopus 로고
    • Angiogenesis in cancer, vascular, rheumatoid and other disease
    • Folkman, J. 1995. Angiogenesis in cancer, vascular, rheumatoid and other disease. Nat. Med. 1:27-31.
    • (1995) Nat. Med. , vol.1 , pp. 27-31
    • Folkman, J.1
  • 7
    • 0031469819 scopus 로고    scopus 로고
    • Antiangiogenic therapy of experimental cancer does not induce acquired drug resistance
    • Boehm, T., J. Folkman, T. Browder, and M.S. O'Reilly. 1997. Antiangiogenic therapy of experimental cancer does not induce acquired drug resistance. Nature 390:404-407.
    • (1997) Nature , vol.390 , pp. 404-407
    • Boehm, T.1    Folkman, J.2    Browder, T.3    O'Reilly, M.S.4
  • 8
    • 0031443206 scopus 로고    scopus 로고
    • A cancer therapy resistant to resistance
    • Kerbel, R.S. 1997. A cancer therapy resistant to resistance. Nature 390:335-336.
    • (1997) Nature , vol.390 , pp. 335-336
    • Kerbel, R.S.1
  • 9
    • 0033041884 scopus 로고    scopus 로고
    • Antiangiogenic therapy of a recurrent giant cell tumor of the mandible with interferon α-2a
    • Kaban, L.B., J.B. Mulliken, R.A. Ezekowitz, D. Ebb, P.S. Smith, and J. Folkman. 1999. Antiangiogenic therapy of a recurrent giant cell tumor of the mandible with interferon α-2a. Pediatrics 103:1145-1149.
    • (1999) Pediatrics , vol.103 , pp. 1145-1149
    • Kaban, L.B.1    Mulliken, J.B.2    Ezekowitz, R.A.3    Ebb, D.4    Smith, P.S.5    Folkman, J.6
  • 10
    • 0029944122 scopus 로고    scopus 로고
    • Angiostatin induces and sustains dormancy of human primary tumors in mice
    • O'Reilly, M.S., L. Holmgren, C. Chen, and J. Folkman. 1996. Angiostatin induces and sustains dormancy of human primary tumors in mice. Nat. Med. 2:689-692.
    • (1996) Nat. Med. , vol.2 , pp. 689-692
    • O'Reilly, M.S.1    Holmgren, L.2    Chen, C.3    Folkman, J.4
  • 11
    • 0033947625 scopus 로고    scopus 로고
    • New anilinophthalazines as potent and orally well absorbed inhibitors of the VEGF receptor tyrosine kinases useful as antagonists of tumor-driven angiogenesis
    • Bold, G., K.H. Altmann, J. Frei, M. Lang, P.W. Manley, P. Traxler, B. Wietfeld, J. Bruggen, et al. 2000. New anilinophthalazines as potent and orally well absorbed inhibitors of the VEGF receptor tyrosine kinases useful as antagonists of tumor-driven angiogenesis. J. Med. Chem. 43:2310-2323.
    • (2000) J. Med. Chem. , vol.43 , pp. 2310-2323
    • Bold, G.1    Altmann, K.H.2    Frei, J.3    Lang, M.4    Manley, P.W.5    Traxler, P.6    Wietfeld, B.7    Bruggen, J.8
  • 12
    • 0031038068 scopus 로고    scopus 로고
    • Expression of the angiogenic factors vascular endothelial cell growth factor, acidic and basic fibroblast growth factor, tumor growth factor β-1, platelet-derived endothelial cell growth factor, placenta growth factor, and pleiotrophin in human primary breast cancer and its relation to angiogenesis
    • Relf, M., S. LeJeune, P.A. Scott, S. Fox, K. Smith, R. Leek, A. Moghaddam, R. Whitehouse, et al. 1997. Expression of the angiogenic factors vascular endothelial cell growth factor, acidic and basic fibroblast growth factor, tumor growth factor β-1, platelet-derived endothelial cell growth factor, placenta growth factor, and pleiotrophin in human primary breast cancer and its relation to angiogenesis. Cancer Res. 57:963-969.
    • (1997) Cancer Res. , vol.57 , pp. 963-969
    • Relf, M.1    LeJeune, S.2    Scott, P.A.3    Fox, S.4    Smith, K.5    Leek, R.6    Moghaddam, A.7    Whitehouse, R.8
  • 14
    • 18844473781 scopus 로고    scopus 로고
    • Epidermal growth factor receptor blockade with C225 plus gemcitabine results in regression of human pancreatic carcinoma growing orthotopically in nude mice by antiangiogenic mechanisms
    • Bruns, C.J., M.T. Harbison, D.W. Davis, C.A. Portera, R. Tsan, D.J. McConkey, D.B. Evans, J.L. Abbruzzese, et al. 2000. Epidermal growth factor receptor blockade with C225 plus gemcitabine results in regression of human pancreatic carcinoma growing orthotopically in nude mice by antiangiogenic mechanisms. Clin. Cancer Res. 6:1936-1948.
    • (2000) Clin. Cancer Res. , vol.6 , pp. 1936-1948
    • Bruns, C.J.1    Harbison, M.T.2    Davis, D.W.3    Portera, C.A.4    Tsan, R.5    McConkey, D.J.6    Evans, D.B.7    Abbruzzese, J.L.8
  • 15
    • 0033927807 scopus 로고    scopus 로고
    • Treatment of human metastatic transitional cell carcinoma of the bladder in a murine model with the anti-vascular endothelial growth factor receptor monoclonal antibody DC101 and paclitaxel
    • Inoue, K., J.W. Slaton, D.W. Davis, D.J. Hicklin, D.J. McConkey, T. Karashima, R. Radinsky, and C.P. Dinney. 2000. Treatment of human metastatic transitional cell carcinoma of the bladder in a murine model with the anti-vascular endothelial growth factor receptor monoclonal antibody DC101 and paclitaxel. Clin. Cancer Res. 6:2635-2643.
    • (2000) Clin. Cancer Res. , vol.6 , pp. 2635-2643
    • Inoue, K.1    Slaton, J.W.2    Davis, D.W.3    Hicklin, D.J.4    McConkey, D.J.5    Karashima, T.6    Radinsky, R.7    Dinney, C.P.8
  • 16
    • 0035043493 scopus 로고    scopus 로고
    • Suppression of angiogenesis and therapy of human colon cancer liver metastasis by systemic administration of interferon-α
    • Ozawa, S., H. Shinohara, H.O. Kanayama, C.J. Bruns, C.D. Bucana, L.M. Ellis, D.W. Davis, and I.J. Fidler. 2001. Suppression of angiogenesis and therapy of human colon cancer liver metastasis by systemic administration of interferon-α. Neoplasia 3:154-164.
    • (2001) Neoplasia , vol.3 , pp. 154-164
    • Ozawa, S.1    Shinohara, H.2    Kanayama, H.O.3    Bruns, C.J.4    Bucana, C.D.5    Ellis, L.M.6    Davis, D.W.7    Fidler, I.J.8
  • 17
    • 0034799139 scopus 로고    scopus 로고
    • A novel approach in the treatment of cancer: Targeting the epidermal growth factor receptor
    • Ciardiello, F. and G. Tortora. 2001. A novel approach in the treatment of cancer: targeting the epidermal growth factor receptor. Clin. Cancer Res. 7:2958-2970.
    • (2001) Clin. Cancer Res. , vol.7 , pp. 2958-2970
    • Ciardiello, F.1    Tortora, G.2
  • 18
    • 0035692285 scopus 로고    scopus 로고
    • Possible mechanisms of acquired resistance to anti-angiogenic drugs: Implications for the use of combination therapy approaches
    • Kerbel, R.S., J. Yu, J. Tran, S. Man, A. Viloria-Petit, G. Klement, B.L. Coomber, and J. Rak. 2001. Possible mechanisms of acquired resistance to anti-angiogenic drugs: implications for the use of combination therapy approaches. Cancer Metastasis Rev. 20:79-86.
    • (2001) Cancer Metastasis Rev. , vol.20 , pp. 79-86
    • Kerbel, R.S.1    Yu, J.2    Tran, J.3    Man, S.4    Viloria-Petit, A.5    Klement, G.6    Coomber, B.L.7    Rak, J.8
  • 19
    • 0036780251 scopus 로고    scopus 로고
    • Clinical translation of angiogenesis inhibitors
    • Kerbel, R. and J. Folkman. 2002. Clinical translation of angiogenesis inhibitors. Nat. Rev. Cancer 2:727-739.
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 727-739
    • Kerbel, R.1    Folkman, J.2
  • 20
    • 0021273420 scopus 로고
    • Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells
    • Ullrich, A., L. Coussens, J.S. Hayflick, T.J. Dull, A. Gray, A.W. Tam, J. Lee, Y. Yarden, et al. 1984. Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells. Nature 309:418-425.
    • (1984) Nature , vol.309 , pp. 418-425
    • Ullrich, A.1    Coussens, L.2    Hayflick, J.S.3    Dull, T.J.4    Gray, A.5    Tam, A.W.6    Lee, J.7    Yarden, Y.8
  • 21
    • 0032823487 scopus 로고    scopus 로고
    • Phase II study of weekly intravenous trastuzumab (Herceptin) in patients with HER2/neu-overexpressing metastatic breast cancer
    • Baselga, J., D. Tripathy, J. Mendelsohn, S. Baughman, C.C. Benz, L. Dantis, N.T. Sklarin, A.D. Seidman, et al. 1999. Phase II study of weekly intravenous trastuzumab (Herceptin) in patients with HER2/neu-overexpressing metastatic breast cancer. Semin. Oncol. 26:78-83.
    • (1999) Semin. Oncol. , vol.26 , pp. 78-83
    • Baselga, J.1    Tripathy, D.2    Mendelsohn, J.3    Baughman, S.4    Benz, C.C.5    Dantis, L.6    Sklarin, N.T.7    Seidman, A.D.8
  • 23
    • 0033964715 scopus 로고    scopus 로고
    • Fluorescence in situ hybridization (FISH) for detection of HER-2/neu amplification in breast cancer: A multicenter portability study
    • Persons, D.L., M.M. Bui, M.C. Lowery, H.F. Mark, J.F. Yung, J.M. Birkmeier, E.Y. Wong, S.J. Yang, et al. 2000. Fluorescence in situ hybridization (FISH) for detection of HER-2/neu amplification in breast cancer: a multicenter portability study. Ann. Clin. Lab. Sci. 30:41-48.
    • (2000) Ann. Clin. Lab. Sci. , vol.30 , pp. 41-48
    • Persons, D.L.1    Bui, M.M.2    Lowery, M.C.3    Mark, H.F.4    Yung, J.F.5    Birkmeier, J.M.6    Wong, E.Y.7    Yang, S.J.8
  • 24
    • 0036214044 scopus 로고    scopus 로고
    • The ErbB receptor family: A therapeutic target for cancer
    • de Bono, J.S. and E.K. Rowinsky. 2002. The ErbB receptor family: a therapeutic target for cancer. Trends Mol. Med. 8:S19-S26.
    • (2002) Trends Mol. Med. , vol.8
    • De Bono, J.S.1    Rowinsky, E.K.2
  • 25
    • 0036139727 scopus 로고    scopus 로고
    • Pharmacodynamic studies of the epidermal growth factor receptor inhibitor ZD1839 in skin from cancer patients: Histopathologic and molecular consequences of receptor inhibition
    • Albanell, J., F. Rojo, S. Averbuch, A. Feyereislova, J.M. Mascaro, R. Herbst, P. LoRusso, D. Rischin, et al. 2002. Pharmacodynamic studies of the epidermal growth factor receptor inhibitor ZD1839 in skin from cancer patients: histopathologic and molecular consequences of receptor inhibition. J. Clin. Oncol. 20:110-124.
    • (2002) J. Clin. Oncol. , vol.20 , pp. 110-124
    • Albanell, J.1    Rojo, F.2    Averbuch, S.3    Feyereislova, A.4    Mascaro, J.M.5    Herbst, R.6    LoRusso, P.7    Rischin, D.8
  • 26
    • 0036842170 scopus 로고    scopus 로고
    • Phase I safety, pharmacokinetic, and pharmacodynamic trial of ZD1839, a selective oral epidermal growth factor receptor tyrosine kinase inhibitor, in patients with five selected solid tumor types
    • Baselga, J., D. Rischin, M. Ranson, H. Calvert, E. Raymond, D.G. Kieback, S.B. Kaye, L. Gianni, et al. 2002. Phase I safety, pharmacokinetic, and pharmacodynamic trial of ZD1839, a selective oral epidermal growth factor receptor tyrosine kinase inhibitor, in patients with five selected solid tumor types. J. Clin. Oncol. 20:4292-4302.
    • (2002) J. Clin. Oncol. , vol.20 , pp. 4292-4302
    • Baselga, J.1    Rischin, D.2    Ranson, M.3    Calvert, H.4    Raymond, E.5    Kieback, D.G.6    Kaye, S.B.7    Gianni, L.8
  • 27
    • 0037106377 scopus 로고    scopus 로고
    • Selective oral epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 is generally well-tolerated and has activity in non-small-cell lung cancer and other solid tumors: Results of a phase I trial
    • Herbst, R.S., A.M. Maddox, M.L. Rothenberg, E.J. Small, E.H. Rubin, J. Baselga, F. Rojo, W.K. Hong, et al. 2002. Selective oral epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 is generally well-tolerated and has activity in non-small-cell lung cancer and other solid tumors: results of a phase I trial. J. Clin. Oncol. 20:3815-3825.
    • (2002) J. Clin. Oncol. , vol.20 , pp. 3815-3825
    • Herbst, R.S.1    Maddox, A.M.2    Rothenberg, M.L.3    Small, E.J.4    Rubin, E.H.5    Baselga, J.6    Rojo, F.7    Hong, W.K.8
  • 28
    • 0036569870 scopus 로고    scopus 로고
    • ZD1839, a selective oral epidermal growth factor receptor-tyrosine kinase inhibitor, is well tolerated and active in patients with solid, malignant tumors: Results of a phase I trial
    • Ranson, M., L.A. Hammond, D. Ferry, M. Kris, A. Tullo, P.I. Murray, V. Miller, S. Averbuch, et al. 2002. ZD1839, a selective oral epidermal growth factor receptor-tyrosine kinase inhibitor, is well tolerated and active in patients with solid, malignant tumors: results of a phase I trial. J. Clin. Oncol. 20:2240-2250.
    • (2002) J. Clin. Oncol. , vol.20 , pp. 2240-2250
    • Ranson, M.1    Hammond, L.A.2    Ferry, D.3    Kris, M.4    Tullo, A.5    Murray, P.I.6    Miller, V.7    Averbuch, S.8
  • 29
    • 0035174127 scopus 로고    scopus 로고
    • Pharmacodynamic studies with the epidermal growth factor receptor tyrosine kinase inhibitor ZD1839
    • Albanell, J., F. Rojo, and J. Baselga. 2001. Pharmacodynamic studies with the epidermal growth factor receptor tyrosine kinase inhibitor ZD1839. Semin. Oncol. 28:56-66.
    • (2001) Semin. Oncol. , vol.28 , pp. 56-66
    • Albanell, J.1    Rojo, F.2    Baselga, J.3
  • 30
    • 0032720628 scopus 로고    scopus 로고
    • Vascular endothelial growth factor effect on endothelial cell proliferation, migration, and plateletactivating factor synthesis is Flk-1-dependent
    • Bernatchez, P.N., S. Soker, and M.G. Sirois. 1999. Vascular endothelial growth factor effect on endothelial cell proliferation, migration, and plateletactivating factor synthesis is Flk-1-dependent. J. Biol. Chem. 274:31047-31054.
    • (1999) J. Biol. Chem. , vol.274 , pp. 31047-31054
    • Bernatchez, P.N.1    Soker, S.2    Sirois, M.G.3
  • 31
    • 0032925147 scopus 로고    scopus 로고
    • Structural analysis of receptor tyrosine kinases
    • Hubbard, S.R. 1999. Structural analysis of receptor tyrosine kinases. Prog. Biophys. Mol. Biol. 71:343-358.
    • (1999) Prog. Biophys. Mol. Biol. , vol.71 , pp. 343-358
    • Hubbard, S.R.1
  • 32
    • 0027466849 scopus 로고
    • High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis
    • Millauer, B., S. Wizigmann-Voos, H. Schnurch, R. Martinez, N.P. Moller, W. Risau, and A. Ullrich. 1993. High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis. Cell 72:835-846.
    • (1993) Cell , vol.72 , pp. 835-846
    • Millauer, B.1    Wizigmann-Voos, S.2    Schnurch, H.3    Martinez, R.4    Moller, N.P.5    Risau, W.6    Ullrich, A.7
  • 33
    • 0027249239 scopus 로고
    • Fetal liver kinase 1 is a receptor for vascular endothelial growth factor and is selectively expressed in vascular endothelium
    • Quinn, T.P., K.G. Peters, C. De Vries, N. Ferrara, and L.T. Williams. 1993. Fetal liver kinase 1 is a receptor for vascular endothelial growth factor and is selectively expressed in vascular endothelium. Proc. Natl. Acad. Sci. USA 90:7533-7537.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 7533-7537
    • Quinn, T.P.1    Peters, K.G.2    De Vries, C.3    Ferrara, N.4    Williams, L.T.5
  • 34
    • 0028174337 scopus 로고
    • Glioblastoma growth inhibited in vivo by a dominant-negative Flk-1 mutant
    • Millauer, B., L.K. Shawver, K.H. Plate, W. Risau, and A. Ullrich. 1994. Glioblastoma growth inhibited in vivo by a dominant-negative Flk-1 mutant. Nature 367:576-579.
    • (1994) Nature , vol.367 , pp. 576-579
    • Millauer, B.1    Shawver, L.K.2    Plate, K.H.3    Risau, W.4    Ullrich, A.5
  • 35
    • 0037087585 scopus 로고    scopus 로고
    • Dose-finding and pharmacokinetic study of cisplatin, gemcitabine, and SU5416 in patients with solid tumors
    • Kuenen, B.C., L. Rosen, E.F. Smit, M.R. Parson, M. Levi, R. Ruijter, H. Huisman, M.A. Kedde, et al. 2002. Dose-finding and pharmacokinetic study of cisplatin, gemcitabine, and SU5416 in patients with solid tumors. J. Clin. Oncol. 20:1657-1667.
    • (2002) J. Clin. Oncol. , vol.20 , pp. 1657-1667
    • Kuenen, B.C.1    Rosen, L.2    Smit, E.F.3    Parson, M.R.4    Levi, M.5    Ruijter, R.6    Huisman, H.7    Kedde, M.A.8
  • 36
    • 0036718003 scopus 로고    scopus 로고
    • Results ofa phase I dose-escalating study of the antiangiogenic agent, SU5416, in patients with advanced malignancies
    • Stopeck, A., M. Sheldon, M. Vahedian, G. Cropp, R. Gosalia, and A. Hannah. 2002. Results ofa phase I dose-escalating study of the antiangiogenic agent, SU5416, in patients with advanced malignancies. Clin. Cancer Res. 8:2798-2805.
    • (2002) Clin. Cancer Res. , vol.8 , pp. 2798-2805
    • Stopeck, A.1    Sheldon, M.2    Vahedian, M.3    Cropp, G.4    Gosalia, R.5    Hannah, A.6
  • 37
    • 0030806173 scopus 로고    scopus 로고
    • Changing views of the role of matrix metalloproteinases in metastasis
    • Chambers, A.F. and L.M. Matrisian. 1997. Changing views of the role of matrix metalloproteinases in metastasis. J. Natl. Cancer Inst. 89:1260-1270.
    • (1997) J. Natl. Cancer Inst. , vol.89 , pp. 1260-1270
    • Chambers, A.F.1    Matrisian, L.M.2
  • 39
    • 0029952713 scopus 로고    scopus 로고
    • Matrix metalloproteinase-1 is associated with poor prognosis in colorectal cancer
    • Murray, G.I., M.E. Duncan, P. O'Neil, W.T. Melvin, and J.E. Fothergill. 1996. Matrix metalloproteinase-1 is associated with poor prognosis in colorectal cancer. Nat. Med. 2:461-462.
    • (1996) Nat. Med. , vol.2 , pp. 461-462
    • Murray, G.I.1    Duncan, M.E.2    O'Neil, P.3    Melvin, W.T.4    Fothergill, J.E.5
  • 40
    • 0033986165 scopus 로고    scopus 로고
    • Phase I and pharmacologic study of the specific matrix metalloproteinase inhibitor BAY 12-9566 on a protracted oral daily dosing schedule in patients with solid malignancies
    • Rowinsky, E.K., R. Humphrey, L.A. Hammond, C. Aylesworth, L. Smetzer, M. Hidalgo, M. Morrow, L. Smith, et al. 2000. Phase I and pharmacologic study of the specific matrix metalloproteinase inhibitor BAY 12-9566 on a protracted oral daily dosing schedule in patients with solid malignancies. J. Clin. Oncol. 18:178-186.
    • (2000) J. Clin. Oncol. , vol.18 , pp. 178-186
    • Rowinsky, E.K.1    Humphrey, R.2    Hammond, L.A.3    Aylesworth, C.4    Smetzer, L.5    Hidalgo, M.6    Morrow, M.7    Smith, L.8
  • 41
    • 0037112183 scopus 로고    scopus 로고
    • Prospective, randomized, double-blind, placebo-controlled trial of marimastat after response to first-line chemotherapy in patients with small-cell lung cancer: A trial of the National Cancer Institute of Canada-Clinical Trials Group and the European Organization for Research and Treatment of Cancer
    • Shepherd, F.A., G. Giaccone, L. Seymour, C. Debruyne, A. Bezjak, V. Hirsh, M. Smylie, S. Rubin, et al. 2002. Prospective, randomized, double-blind, placebo-controlled trial of marimastat after response to first-line chemotherapy in patients with small-cell lung cancer: a trial of the National Cancer Institute of Canada-Clinical Trials Group and the European Organization for Research and Treatment of Cancer. J. Clin. Oncol. 20:4434-4439.
    • (2002) J. Clin. Oncol. , vol.20 , pp. 4434-4439
    • Shepherd, F.A.1    Giaccone, G.2    Seymour, L.3    Debruyne, C.4    Bezjak, A.5    Hirsh, V.6    Smylie, M.7    Rubin, S.8
  • 42
    • 0034772722 scopus 로고    scopus 로고
    • Phase I and pharmacological study of the oral matrix metalloproteinase inhibitor, MM1270 (CGS27023A), in patients with advanced solid cancer
    • Levitt, N.C., F.A. Eskens, K.J. O'Byrne, D.J. Propper, L.J. Denis, S.J. Owen, L. Choi, J.A. Foekens, et al. 2001. Phase I and pharmacological study of the oral matrix metalloproteinase inhibitor, MM1270 (CGS27023A), in patients with advanced solid cancer. Clin. Cancer Res. 7:1912-1922.
    • (2001) Clin. Cancer Res. , vol.7 , pp. 1912-1922
    • Levitt, N.C.1    Eskens, F.A.2    O'Byrne, K.J.3    Propper, D.J.4    Denis, L.J.5    Owen, S.J.6    Choi, L.7    Foekens, J.A.8
  • 43
    • 0035863463 scopus 로고    scopus 로고
    • Phase I clinical trial of oral COL-3, a matrix metalloproteinase inhibitor, in patients with refractory metastatic cancer
    • Rudek, M.A., W.D. Figg, V. Dyer, W. Dahut, M.L. Turner, S.M. Steinberg, D.J. Liewehr, D.R. Kohler, et al. 2001. Phase I clinical trial of oral COL-3, a matrix metalloproteinase inhibitor, in patients with refractory metastatic cancer. J. Clin. Oncol. 19:584-592.
    • (2001) J. Clin. Oncol. , vol.19 , pp. 584-592
    • Rudek, M.A.1    Figg, W.D.2    Dyer, V.3    Dahut, W.4    Turner, M.L.5    Steinberg, S.M.6    Liewehr, D.J.7    Kohler, D.R.8
  • 44
    • 0037112010 scopus 로고    scopus 로고
    • Safety and pharmacokinetic effects of TNP-470, an angiogenesis inhibitor, combined with paclitaxel in patients with solid tumors: Evidence for activity in non-small-cell lung cancer
    • Herbst, R.S., T.L. Madden, H.T. Tran, G.R. Blumenschein, Jr., C.A. Meyers, L.F. Seabrooke, F.R. Khuri, V.K. Puduvalli, et al. 2002. Safety and pharmacokinetic effects of TNP-470, an angiogenesis inhibitor, combined with paclitaxel in patients with solid tumors: evidence for activity in non-small-cell lung cancer. J. Clin. Oncol. 20:4440-4447.
    • (2002) J. Clin. Oncol. , vol.20 , pp. 4440-4447
    • Herbst, R.S.1    Madden, T.L.2    Tran, H.T.3    Blumenschein G.R., Jr.4    Meyers, C.A.5    Seabrooke, L.F.6    Khuri, F.R.7    Puduvalli, V.K.8
  • 45
    • 0036579996 scopus 로고    scopus 로고
    • The combination of antiangiogenic therapy with other modalities
    • O'Reilly, M.S. 2002. The combination of antiangiogenic therapy with other modalities. Cancer J. 8(Suppl 1):S89-S99.
    • (2002) Cancer J. , vol.8 , Issue.SUPPL. 1
    • O'Reilly, M.S.1
  • 48
    • 0035291168 scopus 로고    scopus 로고
    • Clinical studies of angiogenesis inhibitors: The University of Texas MD Anderson Center trial of human endostatin
    • Herbst, R.S., A.T. Lee, H.T. Tran, and J.L. Abbruzzese. 2001. Clinical studies of angiogenesis inhibitors: the University of Texas MD Anderson Center trial of human endostatin. Curr. Oncol. Rep. 3:131-140.
    • (2001) Curr. Oncol. Rep. , vol.3 , pp. 131-140
    • Herbst, R.S.1    Lee, A.T.2    Tran, H.T.3    Abbruzzese, J.L.4
  • 49
    • 0037106384 scopus 로고    scopus 로고
    • Development of biologic markers of response and assessment of antiangiogenic activity in a clinical trial of human recombinant endostatin
    • Herbst, R.S., N.A. Mullani, D.W. Davis, K.R. Hess, D.J. McConkey, C. Charnsangavej, M.S. O'Reilly, H.W. Kim, et al. 2002. Development of biologic markers of response and assessment of antiangiogenic activity in a clinical trial of human recombinant endostatin. J. Clin. Oncol. 20:3804-3814.
    • (2002) J. Clin. Oncol. , vol.20 , pp. 3804-3814
    • Herbst, R.S.1    Mullani, N.A.2    Davis, D.W.3    Hess, K.R.4    McConkey, D.J.5    Charnsangavej, C.6    O'Reilly, M.S.7    Kim, H.W.8
  • 50
    • 0034488576 scopus 로고    scopus 로고
    • A phase II study of razoxane, an antiangiogenic topoisomerase II inhibitor, in renal cell cancer with assessment of potential surrogate markers of angiogenesis
    • Braybrooke, J.P., K.J. O'Byrne, D.J. Propper, A. Blann, M. Saunders, N. Dobbs, C. Han, J. Woodhull, et al. 2000. A phase II study of razoxane, an antiangiogenic topoisomerase II inhibitor, in renal cell cancer with assessment of potential surrogate markers of angiogenesis. Clin. Cancer Res. 6:4697-4704.
    • (2000) Clin. Cancer Res. , vol.6 , pp. 4697-4704
    • Braybrooke, J.P.1    O'Byrne, K.J.2    Propper, D.J.3    Blann, A.4    Saunders, M.5    Dobbs, N.6    Han, C.7    Woodhull, J.8
  • 51
    • 0035383784 scopus 로고    scopus 로고
    • Resting and activated endothelial cells are increased in the peripheral blood ofcancer patients
    • Mancuso, P., A. Burlini, G. Pruneri, A. Goldhirsch, G. Martinelli, and F. Bertolini. 2001. Resting and activated endothelial cells are increased in the peripheral blood ofcancer patients. Blood 97:3658-3661.
    • (2001) Blood , vol.97 , pp. 3658-3661
    • Mancuso, P.1    Burlini, A.2    Pruneri, G.3    Goldhirsch, A.4    Martinelli, G.5    Bertolini, F.6
  • 52
    • 0035160312 scopus 로고    scopus 로고
    • Impaired recruitment of bone-marrow-derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth
    • Lyden, D., K. Hattori, S. Dias, C. Costa, P. Blaikie, L. Butros, A. Chadburn, B. Heissig, et al. 2001. Impaired recruitment of bone-marrow-derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth. Nat. Med. 7:1194-1201.
    • (2001) Nat. Med. , vol.7 , pp. 1194-1201
    • Lyden, D.1    Hattori, K.2    Dias, S.3    Costa, C.4    Blaikie, P.5    Butros, L.6    Chadburn, A.7    Heissig, B.8
  • 53
    • 0036831559 scopus 로고    scopus 로고
    • Vascular and haematopoietic stem cells: Novel targets for anti-angiogenesis therapy?
    • Rafii, S., D. Lyden, R. Benezra, K. Hattori, and B. Heissig. 2002. Vascular and haematopoietic stem cells: novel targets for anti-angiogenesis therapy? Nat. Rev. Cancer 2:826-835.
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 826-835
    • Rafii, S.1    Lyden, D.2    Benezra, R.3    Hattori, K.4    Heissig, B.5
  • 54
    • 0035000463 scopus 로고    scopus 로고
    • Endothelialization of PTFE vascular grafts under flow induces significant cell changes
    • Rademacher, A., M. Paulitschke, R. Meyer, and R. Hetzer. 2001. Endothelialization of PTFE vascular grafts under flow induces significant cell changes. Int. J. Artif. Organs 24:235-242.
    • (2001) Int. J. Artif. Organs , vol.24 , pp. 235-242
    • Rademacher, A.1    Paulitschke, M.2    Meyer, R.3    Hetzer, R.4
  • 55
    • 0035371837 scopus 로고    scopus 로고
    • Proteomics: A technology-driven and technology-limited discovery science
    • Lee, K.H. 2001. Proteomics: a technology-driven and technology-limited discovery science. Trends Biotechnol. 19:217-222.
    • (2001) Trends Biotechnol. , vol.19 , pp. 217-222
    • Lee, K.H.1
  • 56
    • 0035207172 scopus 로고    scopus 로고
    • Platelet-derived growth factor receptors: A therapeutic target in solid tumors
    • George, D. 2001. Platelet-derived growth factor receptors: a therapeutic target in solid tumors. Semin. Oncol. 28:27-33.
    • (2001) Semin. Oncol. , vol.28 , pp. 27-33
    • George, D.1
  • 57
    • 0033763567 scopus 로고    scopus 로고
    • Involvement of platelet-derived growth factor in disease: Development of specific antagonists
    • Ostman, A. and C.H. Heldin. 2001. Involvement of platelet-derived growth factor in disease: development of specific antagonists. Adv. Cancer Res. 80:1-38.
    • (2001) Adv. Cancer Res. , vol.80 , pp. 1-38
    • Ostman, A.1    Heldin, C.H.2
  • 58
    • 0021798948 scopus 로고
    • Synthesis and secretion of proteins resembling platelet-derived growth factor by human glioblastoma and fibrosarcoma cells in culture
    • Pantazis, P., P.G. Pelicci, R. Dalla-Favera, and H.N. Antoniades. 1985. Synthesis and secretion of proteins resembling platelet-derived growth factor by human glioblastoma and fibrosarcoma cells in culture. Proc. Natl. Acad. Sci. USA 82:2404-2408.
    • (1985) Proc. Natl. Acad. Sci. USA , vol.82 , pp. 2404-2408
    • Pantazis, P.1    Pelicci, P.G.2    Dalla-Favera, R.3    Antoniades, H.N.4
  • 59
    • 10744227995 scopus 로고    scopus 로고
    • Effects of blocking platelet-derived growth factor-receptor signaling in a mouse model of experimental prostate cancer bone metastases
    • Uehara, H., S.J. Kim, T. Karashima, D.L. Shepherd, D. Fan, R. Tsan, J.J. Killion, C. Logothetis, et al. 2003. Effects of blocking platelet-derived growth factor-receptor signaling in a mouse model of experimental prostate cancer bone metastases. J. Natl. Cancer Inst. 95:458-470.
    • (2003) J. Natl. Cancer Inst. , vol.95 , pp. 458-470
    • Uehara, H.1    Kim, S.J.2    Karashima, T.3    Shepherd, D.L.4    Fan, D.5    Tsan, R.6    Killion, J.J.7    Logothetis, C.8
  • 60
    • 0033231069 scopus 로고    scopus 로고
    • Antiangiogenic therapy targeting the tyrosine kinase receptor for vascular endothelial growth factor receptor inhibits the growth of colon cancer liver metastasis and induces tumor and endothelial cell apoptosis
    • Shaheen, R.M., D.W. Davis, W. Liu, B.K. Zebrowski, M.R. Wilson, C.D. Bucana, D.J. McConkey, et al. 1999. Antiangiogenic therapy targeting the tyrosine kinase receptor for vascular endothelial growth factor receptor inhibits the growth of colon cancer liver metastasis and induces tumor and endothelial cell apoptosis. Cancer Res. 59:5412-5416.
    • (1999) Cancer Res. , vol.59 , pp. 5412-5416
    • Shaheen, R.M.1    Davis, D.W.2    Liu, W.3    Zebrowski, B.K.4    Wilson, M.R.5    Bucana, C.D.6    McConkey, D.J.7
  • 62
    • 0034489116 scopus 로고    scopus 로고
    • Paclitaxel enhances the effects of the anti-epidermal growth factor receptor monoclonal antibody ImClone C225 in mice with metastatic human bladder transitional cell carcinoma
    • Inoue, K., J.W. Slaton, P. Perrotte, D.W. Davis, C.J. Bruns, D.J. Hicklin, D.J. McConkey, P. Sweeney, et al. 2000. Paclitaxel enhances the effects of the anti-epidermal growth factor receptor monoclonal antibody ImClone C225 in mice with metastatic human bladder transitional cell carcinoma. Clin. Cancer Res. 6:4874-4884.
    • (2000) Clin. Cancer Res. , vol.6 , pp. 4874-4884
    • Inoue, K.1    Slaton, J.W.2    Perrotte, P.3    Davis, D.W.4    Bruns, C.J.5    Hicklin, D.J.6    McConkey, D.J.7    Sweeney, P.8
  • 63
    • 0037339961 scopus 로고    scopus 로고
    • Automated quantification ofapoptosis after neoadjuvant chemotherapy for breast cancer: Early assessment predicts clinical response
    • Davis, D.W., T.A. Buchholz, K.R. Hess, A.A. Sahin, V. Valero, and D.J. McConkey. 2003. Automated quantification ofapoptosis after neoadjuvant chemotherapy for breast cancer: early assessment predicts clinical response. Clin. Cancer Res. 9:955-960.
    • (2003) Clin. Cancer Res. , vol.9 , pp. 955-960
    • Davis, D.W.1    Buchholz, T.A.2    Hess, K.R.3    Sahin, A.A.4    Valero, V.5    McConkey, D.J.6
  • 65
    • 0037229674 scopus 로고    scopus 로고
    • Microarray reveals differences in both tumors and vascular specific gene expression in de novo CD5+ and CD5-diffuse large B-cell lymphomas
    • Kobayashi, T., M. Yamaguchi, S. Kim, J. Morikawa, S. Ogawa, S. Ueno, E. Suh, E. Dougherty, et al. 2003. Microarray reveals differences in both tumors and vascular specific gene expression in de novo CD5+ and CD5-diffuse large B-cell lymphomas. Cancer Res. 63:60-66.
    • (2003) Cancer Res. , vol.63 , pp. 60-66
    • Kobayashi, T.1    Yamaguchi, M.2    Kim, S.3    Morikawa, J.4    Ogawa, S.5    Ueno, S.6    Suh, E.7    Dougherty, E.8
  • 66
    • 0034901273 scopus 로고    scopus 로고
    • A phase I trial of carboxyamido-triazole and paclitaxel for relapsed solid tumors: Potential efficacy of the combination and demonstration of pharmacokinetic interaction
    • Kohn, E.C., E. Reed, G.A. Sarosy, L. Minasian, K.S. Bauer, F. Bostick-Bruton, V. Kulpa, E. Fuse, et al. 2001. A phase I trial of carboxyamido-triazole and paclitaxel for relapsed solid tumors: potential efficacy of the combination and demonstration of pharmacokinetic interaction. Clin. Cancer Res. 7:1600-1609.
    • (2001) Clin. Cancer Res. , vol.7 , pp. 1600-1609
    • Kohn, E.C.1    Reed, E.2    Sarosy, G.A.3    Minasian, L.4    Bauer, K.S.5    Bostick-Bruton, F.6    Kulpa, V.7    Fuse, E.8
  • 67
    • 0036839013 scopus 로고    scopus 로고
    • Immunomodulatory drug CC-5013 overcomes drug resistance and is well tolerated in patients with relapsed multiple myeloma
    • Richardson, P.G., R.L. Schlossman, E. Weller, T. Hideshima, C. Mitsiades, F. Davies, R. LeBlanc, L.P. Catley, et al. 2002. Immunomodulatory drug CC-5013 overcomes drug resistance and is well tolerated in patients with relapsed multiple myeloma. Blood 100:3063-3067.
    • (2002) Blood , vol.100 , pp. 3063-3067
    • Richardson, P.G.1    Schlossman, R.L.2    Weller, E.3    Hideshima, T.4    Mitsiades, C.5    Davies, F.6    LeBlanc, R.7    Catley, L.P.8
  • 68
    • 0033870756 scopus 로고    scopus 로고
    • Targeted antiangiogenic therapy for cancer using Vitaxin: A humanized monoclonal antibody to the integrin alphav-beta3
    • Gutheil, J.C., T.N. Campbell, P.R. Pierce, J.D. Watkins, W.D. Huse, D.J. Bodkin, and D.A. Cheresh. 2000. Targeted antiangiogenic therapy for cancer using Vitaxin: a humanized monoclonal antibody to the integrin alphav-beta3. Clin. Cancer Res. 6:3056-3061.
    • (2000) Clin. Cancer Res. , vol.6 , pp. 3056-3061
    • Gutheil, J.C.1    Campbell, T.N.2    Pierce, P.R.3    Watkins, J.D.4    Huse, W.D.5    Bodkin, D.J.6    Cheresh, D.A.7
  • 69
    • 0036016485 scopus 로고    scopus 로고
    • Effects of IL-2 preoperative immunotherapy on surgery-induced changes in angiogenic regulation and its prevention of VEGF increase and IL-12 decline
    • Brivio, F., P. Lissoni, F. Rovelli, A. Nespoli, F. Uggeri, L. Fumagalli, and G. Gardani. 2002. Effects of IL-2 preoperative immunotherapy on surgery-induced changes in angiogenic regulation and its prevention of VEGF increase and IL-12 decline. Hepatogastroenterology 49:385-387.
    • (2002) Hepatogastroenterology , vol.49 , pp. 385-387
    • Brivio, F.1    Lissoni, P.2    Rovelli, F.3    Nespoli, A.4    Uggeri, F.5    Fumagalli, L.6    Gardani, G.7
  • 73
    • 0033772376 scopus 로고    scopus 로고
    • Thalidomide therapy in refractory solid tumour patients
    • Gutheil, J. and D. Finucane. 2000. Thalidomide therapy in refractory solid tumour patients. Br. J. Haematol. 110:754.
    • (2000) Br. J. Haematol. , vol.110 , pp. 754
    • Gutheil, J.1    Finucane, D.2
  • 74
    • 0034795178 scopus 로고    scopus 로고
    • A randomized phase II trial of docetaxel (taxotere) plus thalidomide in androgen-independent prostate cancer
    • Figg, W.D., P. Arlen, J. Gulley, P. Fernandez, M. Noone, K. Fedenko, M. Hamilton, C. Parker, et al. 2001. A randomized phase II trial of docetaxel (taxotere) plus thalidomide in androgen-independent prostate cancer. Semin. Oncol. 28:62-66.
    • (2001) Semin. Oncol. , vol.28 , pp. 62-66
    • Figg, W.D.1    Arlen, P.2    Gulley, J.3    Fernandez, P.4    Noone, M.5    Fedenko, K.6    Hamilton, M.7    Parker, C.8
  • 77
    • 0035671824 scopus 로고    scopus 로고
    • A phase I and pharmacokinetic study of squalamine, a novel antiangiogenic agent, in patients with advanced cancers
    • Bhargava, P., J.L. Marshall, W. Dahut, N. Rizvi, N. Trocky, J.I. Williams, H. Hait, S. Song, et al. 2001. A phase I and pharmacokinetic study of squalamine, a novel antiangiogenic agent, in patients with advanced cancers. Clin. Cancer Res. 7:3912-3919.
    • (2001) Clin. Cancer Res. , vol.7 , pp. 3912-3919
    • Bhargava, P.1    Marshall, J.L.2    Dahut, W.3    Rizvi, N.4    Trocky, N.5    Williams, J.I.6    Hait, H.7    Song, S.8
  • 78
    • 0037106501 scopus 로고    scopus 로고
    • Effects of 5,6-dimethylx-anthenone-4-acetic acid on human tumor microcirculation assessed by dynamic contrast-enhanced magnetic resonance imaging
    • Galbraith, S.M., G.J. Rustin, M.A. Lodge, N.J. Taylor, J.J. Stirling, M. Jameson, P. Thompson, D. Hough, et al. 2002. Effects of 5,6-dimethylx-anthenone-4-acetic acid on human tumor microcirculation assessed by dynamic contrast-enhanced magnetic resonance imaging. J. Clin. Oncol. 20:3826-3840.
    • (2002) J. Clin. Oncol. , vol.20 , pp. 3826-3840
    • Galbraith, S.M.1    Rustin, G.J.2    Lodge, M.A.3    Taylor, N.J.4    Stirling, J.J.5    Jameson, M.6    Thompson, P.7    Hough, D.8
  • 81
    • 0037440123 scopus 로고    scopus 로고
    • Phase I pharmacokinetic and pharmacodynamic study of recombinant human endostatin in patients with advanced solid tumors
    • Thomas, J.P., R.Z. Arzoomanian, D. Alberti, R. Marnocha, F. Lee, A. Friedl, K. Tutsch, A. Dresen, et al. 2003. Phase I pharmacokinetic and pharmacodynamic study of recombinant human endostatin in patients with advanced solid tumors. J. Clin. Oncol. 21:223-231.
    • (2003) J. Clin. Oncol. , vol.21 , pp. 223-231
    • Thomas, J.P.1    Arzoomanian, R.Z.2    Alberti, D.3    Marnocha, R.4    Lee, F.5    Friedl, A.6    Tutsch, K.7    Dresen, A.8
  • 82
    • 0036333725 scopus 로고    scopus 로고
    • MRI monitoring of tumor response to a novel VEGF tyrosine kinase inhibitor in an experimental breast cancer model
    • Turetschek, K., A. Preda, E. Floyd, D.M. Shames, V. Novikov, T.P. Roberts, J.M. Wood, Y. Fu, et al. 2002. MRI monitoring of tumor response to a novel VEGF tyrosine kinase inhibitor in an experimental breast cancer model. Acad. Radiol. 9(Suppl) 2:S519-S520.
    • (2002) Acad. Radiol. , vol.9 , Issue.2 SUPPL.
    • Turetschek, K.1    Preda, A.2    Floyd, E.3    Shames, D.M.4    Novikov, V.5    Roberts, T.P.6    Wood, J.M.7    Fu, Y.8
  • 83
    • 0037009827 scopus 로고    scopus 로고
    • Molecular imaging and biological evaluation of HuMV833 anti-VEGF antibody: Implications for trial design of antiangiogenic antibodies
    • Jayson, G.C., J. Zweit, A. Jackson, C. Mulatero, P. Julyan, M. Ranson, L. Broughton, J. Wagstaff, et al. 2002. Molecular imaging and biological evaluation of HuMV833 anti-VEGF antibody: implications for trial design of antiangiogenic antibodies. J. Natl. Cancer Inst. 94:1484-1493.
    • (2002) J. Natl. Cancer Inst. , vol.94 , pp. 1484-1493
    • Jayson, G.C.1    Zweit, J.2    Jackson, A.3    Mulatero, C.4    Julyan, P.5    Ranson, M.6    Broughton, L.7    Wagstaff, J.8
  • 84
    • 0035253739 scopus 로고    scopus 로고
    • Phase I safety and pharmaco-kinetic study of recombinant human anti-vascular endothelial growth factor in patients with advanced cancer
    • Gordon, M.S., K. Margolin, M. Talpaz, G.W. Sledge, Jr., E. Holmgren, R. Benjamin, S. Stalter, S. Shak, et al. 2001. Phase I safety and pharmaco-kinetic study of recombinant human anti-vascular endothelial growth factor in patients with advanced cancer. J. Clin. Oncol. 19:843-850.
    • (2001) J. Clin. Oncol. , vol.19 , pp. 843-850
    • Gordon, M.S.1    Margolin, K.2    Talpaz, M.3    Sledge G.W., Jr.4    Holmgren, E.5    Benjamin, R.6    Stalter, S.7    Shak, S.8
  • 86
    • 0035431418 scopus 로고    scopus 로고
    • Clinical trials referral resource: Current clinical trials of the anti-VEGF monoclonal antibody bevacizumab
    • Chen, H.X., R.E. Gore-Langton, and B.D. Cheson. 2001. Clinical trials referral resource: current clinical trials of the anti-VEGF monoclonal antibody bevacizumab. Oncology 15:1017-1026.
    • (2001) Oncology , vol.15 , pp. 1017-1026
    • Chen, H.X.1    Gore-Langton, R.E.2    Cheson, B.D.3
  • 87
    • 0037208589 scopus 로고    scopus 로고
    • Phase II, randomized trial comparing bevacizumab plus fluorouracil (FU)/leucovorin (LV) with FU/LV alone in patients with metastatic colorectal cancer
    • Kabbinavar, F., H.I. Hurwitz, L. Fehrenbacher, N.J. Meropol, W.F. Novotny, G. Lieberman, S. Griffing, and E. Bergsland. 2003. Phase II, randomized trial comparing bevacizumab plus fluorouracil (FU)/leucovorin (LV) with FU/LV alone in patients with metastatic colorectal cancer. J. Clin. Oncol. 21:60-65.
    • (2003) J. Clin. Oncol. , vol.21 , pp. 60-65
    • Kabbinavar, F.1    Hurwitz, H.I.2    Fehrenbacher, L.3    Meropol, N.J.4    Novotny, W.F.5    Lieberman, G.6    Griffing, S.7    Bergsland, E.8
  • 88
    • 0037217219 scopus 로고    scopus 로고
    • Temozolomide in combination with interferon α-2b in patients with metastatic melanoma: A phase I dose-escalation study
    • Agarwala, S.S. and J.M. Kirkwood. 2003. Temozolomide in combination with interferon α-2b in patients with metastatic melanoma: a phase I dose-escalation study. Cancer 97:121-127.
    • (2003) Cancer , vol.97 , pp. 121-127
    • Agarwala, S.S.1    Kirkwood, J.M.2
  • 89
    • 0028858025 scopus 로고
    • Dose-dependent access of murine anti-epidermal growth factor receptor monoclonal antibody to tumor cells in patients with advanced laryngeal and hypopharyngeal carcinoma
    • Bier, H., K.A. Reiffen, I. Haas, and P. Stasiecki. 1995. Dose-dependent access of murine anti-epidermal growth factor receptor monoclonal antibody to tumor cells in patients with advanced laryngeal and hypopharyngeal carcinoma. Eur. Arch. Otorhinolaryngol. 252:433-439.
    • (1995) Eur. Arch. Otorhinolaryngol. , vol.252 , pp. 433-439
    • Bier, H.1    Reiffen, K.A.2    Haas, I.3    Stasiecki, P.4
  • 90
    • 0029064743 scopus 로고
    • The epidermal growth factor receptor in glioblastoma: Genomic amplification, protein expression, and patient survival data in a therapeutic trial
    • Schober, R., T. Bilzer, A. Waha, G. Reifenberger, W. Wechsler, A. von Deimling, O.D. Wiestler, M. Westphal, et al. 1995. The epidermal growth factor receptor in glioblastoma: genomic amplification, protein expression, and patient survival data in a therapeutic trial. Clin. Neuropathol. 14:169-174.
    • (1995) Clin. Neuropathol. , vol.14 , pp. 169-174
    • Schober, R.1    Bilzer, T.2    Waha, A.3    Reifenberger, G.4    Wechsler, W.5    Von Deimling, A.6    Wiestler, O.D.7    Westphal, M.8
  • 91
    • 0035398021 scopus 로고    scopus 로고
    • Phase I study of anti-epidermal growth factor receptor antibody cetuximab in combination with radiation therapy in patients with advanced head and neck cancer
    • Robert, F., M.P. Ezekiel, S.A. Spencer, R.E Meredith, J.A. Bonner, M.B. Khazaeli, M.N. Saleh, D. Carey, et al. 2001. Phase I study of anti - epidermal growth factor receptor antibody cetuximab in combination with radiation therapy in patients with advanced head and neck cancer. J. Clin. Oncol. 19:3234-3243.
    • (2001) J. Clin. Oncol. , vol.19 , pp. 3234-3243
    • Robert, F.1    Ezekiel, M.P.2    Spencer, S.A.3    Meredith, R.E.4    Bonner, J.A.5    Khazaeli, M.B.6    Saleh, M.N.7    Carey, D.8
  • 93
    • 0035398631 scopus 로고    scopus 로고
    • Phase I and pharmacologic study of OSI-774, an epidermal growth factor receptor tyrosine kinase inhibitor, in patients with advanced solid malignancies
    • Hidalgo, M., L.L. Siu, J. Nemunaitis, J. Rizzo, L.A. Hammond, C. Takimoto, S.G. Eckhardt, A. Tolcher, et al. 2001. Phase I and pharmacologic study of OSI-774, an epidermal growth factor receptor tyrosine kinase inhibitor, in patients with advanced solid malignancies. J. Clin. Oncol. 19:3267-3279.
    • (2001) J. Clin. Oncol. , vol.19 , pp. 3267-3279
    • Hidalgo, M.1    Siu, L.L.2    Nemunaitis, J.3    Rizzo, J.4    Hammond, L.A.5    Takimoto, C.6    Eckhardt, S.G.7    Tolcher, A.8
  • 94
    • 0035372452 scopus 로고    scopus 로고
    • OSI Pharmaceuticals, Genentech and Roche announce data from clinical studies of Tarceva. 2001. Expert Review of Anticancer Therapy 1:4-5.
    • (2001) Expert Review of Anticancer Therapy , vol.1 , pp. 4-5
  • 96
    • 0034900427 scopus 로고    scopus 로고
    • A multi-institutional phase II study of SU101, a platelet-derived growth factor receptor inhibitor, for patients with hormone-refractory prostate cancer
    • Ko, Y.J., E.J. Small, F. Kabbinavar, A. Chachoua, S. Taneja, D. Reese, A. DePaoli, A. Hannah, et al. 2001. A multi-institutional phase II study of SU101, a platelet-derived growth factor receptor inhibitor, for patients with hormone-refractory prostate cancer. Clin. Cancer Res. 7:800-805.
    • (2001) Clin. Cancer Res. , vol.7 , pp. 800-805
    • Ko, Y.J.1    Small, E.J.2    Kabbinavar, F.3    Chachoua, A.4    Taneja, S.5    Reese, D.6    DePaoli, A.7    Hannah, A.8
  • 97
    • 0033957239 scopus 로고    scopus 로고
    • Results of a randomized study of IM862 nasal solution in the treatment of AIDS-related Kaposi's sarcoma
    • Tulpule, A., D.T. Scadden, B.M. Espina, S. Cabriales, W. Howard, K. Shea, and P.S. Gill. 2000. Results of a randomized study of IM862 nasal solution in the treatment of AIDS-related Kaposi's sarcoma. J. Clin. Oncol. 18:716-723.
    • (2000) J. Clin. Oncol. , vol.18 , pp. 716-723
    • Tulpule, A.1    Scadden, D.T.2    Espina, B.M.3    Cabriales, S.4    Howard, W.5    Shea, K.6    Gill, P.S.7
  • 98
    • 0036668668 scopus 로고    scopus 로고
    • Neovastat (AE-941) in refractory renal cell carcinoma patients: Report of a phase II trial with two dose levels
    • Batist, G., F. Patenaude, P. Champagne, D. Croteau, C. Levinton, C. Hariton, B. Escudier, and E. Dupont. 2002. Neovastat (AE-941) in refractory renal cell carcinoma patients: report of a phase II trial with two dose levels. Ann. Oncol. 13:1259-1263.
    • (2002) Ann. Oncol. , vol.13 , pp. 1259-1263
    • Batist, G.1    Patenaude, F.2    Champagne, P.3    Croteau, D.4    Levinton, C.5    Hariton, C.6    Escudier, B.7    Dupont, E.8


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