Interaction of the 18.5-kD isoform of myelin basic protein with Ca2+-calmodulin: Effects of deimination assessed by intrinsic Trp fluorescence spectroscopy, dynamic light scattering, and circular dichroism

Protein Science

Volumn 12, Issue 7, 2003, Pages 1507-1521

  Libich, David S ^a   Hill, Christopher ^a   Bates, Ian R ^a   Hallett, F Ross ^a   Armstrong, Souzan ^b   Siemiarczuk, Aleksander ^b   Harauz, George ^a  

^a UNIVERSITY OF GUELPH   (Canada)

^b Photon Technology International Canada Inc   (Canada)

Author keywords

Calmodulin; Circular dichroism; Citrulline; Deimination; Dynamic light scattering; Fluorescence lifetime; Intrinsic Trp fluorescence; Multiple sclerosis; Myelin basic protein

Indexed keywords

ACRYLAMIDE; ARGININE; CALCIUM; CALMODULIN; CITRULLINE; MYELIN BASIC PROTEIN; PROTEIN; RECOMBINANT MURINE MYELIN BASIC PROTEIN; UNCLASSIFIED DRUG;

AMINATION; ARTICLE; BINDING SITE; CIRCULAR DICHROISM; CONFORMATIONAL TRANSITION; DEIMINATION; DISSOCIATION CONSTANT; DYNAMIC LIGHT SCATTERING; FLUORESCENCE; FLUORESCENCE SPECTROSCOPY; LIGHT SCATTERING; MOLECULAR DYNAMICS; MULTIPLE SCLEROSIS; NONPHOTOCHEMICAL QUENCHING; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN INTERACTION; PROTEIN SECONDARY STRUCTURE; STEADY STATE; STOICHIOMETRY;

ACRYLAMIDES; AMINO ACID SEQUENCE; ANIMALS; CALCIUM; CALMODULIN; CATIONS, DIVALENT; CIRCULAR DICHROISM; CITRULLINE; HUMANS; MOLECULAR SEQUENCE DATA; MULTIPLE SCLEROSIS; MYELIN BASIC PROTEINS; PROTEIN ISOFORMS; SCATTERING, RADIATION; SPECTROMETRY, FLUORESCENCE;

MURINAE;

EID: 0037972256     PISSN: 09618368     EISSN: None     Source Type: Journal    
DOI: 10.1110/ps.0303603     Document Type: Article

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