UP1 extends life of primary porcine fetal fibroblasts in culture

Cloning and Stem Cells

Volumn 5, Issue 2, 2003, Pages 143-148

  Mir, Bashir ^a   Tanner, Natalie ^b   Chowdhary, Bhanu P ^b   Piedrahita, Jorge A ^a  

^a NORTH CAROLINA STATE UNIVERSITY   (United States)

^b TEXAS A AND M UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOXIDANT; GLUTATHIONE; N TERT BUTYL HYDROXYLAMINE; PROTEIN; PROTEIN UP1; UNCLASSIFIED DRUG;

ALLELE; ANIMAL CELL; ARTICLE; CELL CULTURE; CELL NUCLEUS TRANSPLANTATION; CELL SURVIVAL; CHROMOSOME ABERRATION; CLONE; CONTROLLED STUDY; DNA MODIFICATION; FETUS; FIBROBLAST; GENE TARGETING; KARYOTYPE; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; SOMATIC CELL;

ANIMALIA; SUIDAE;

EID: 0037962249     PISSN: 15362302     EISSN: None     Source Type: Journal    
DOI: 10.1089/153623003322234740     Document Type: Article

References (16)

1. Atanma, H., Paler-Martinez, A., and Ames, B.N. (2000). N-t-Butyl hydroxylamine, a hydrolysis product of α-phenyl-N-t-butyl nitrone, is more potent in delaying senescence in human lung fibroblasts. J. Biol. Chem. 275, 6741-6748.
2. Bodnar, A.G., Ouellette, M., Frolkis, M., et al. (1998). Extension of life-span by introduction of telomerase into normal human cells. Science 279, 349-352.
3. Clark, A.J., Burl, S., Denning, C. et al. (2000). Gene targeting in livestock - a preview. Transgenic Res. 9, 263-275.
4. Dallaire, F., Dupuis, S., Fiset, S. et al. (2000). Heterogeneous nuclear ribonucleoprotein A1 and UP1 protect mammalian telomeric repeats and modulate telomere replication in vitro. J. Biol. Chem. 275, 14509-14516.
5. Denning, C., Dickinson, P., Burl, S., et al. (2001). Gene targeting in primary fetal fibroblasts from sheep and pig. Cloning Stem Cells 3, 221-231.
6. Falanga, V., and Kirsner, R.S. (1993). Low oxygen stimulates proliferation of fibroblasts seeded as single cells. J. Cell Physiol. 154, 506-510.
7. Gallaher, D.S., Jr., Basrun, P.K., and Womack, J.E. (1992). Identification of an autosome to X chromosome translocation in the domestic cow. J. Hered. 83, 451-453.
8. Kasinathan, P., Knott, J.G., Moreira, P.N., et al. (2001). Effect of fibroblast donor cell age and cell cycle on development of bovine donor cell age and cell cycle on development of bovine nuclear transfer embryos in vitro. Biol. Reprod. 64, 1487-1493.
9. LaBranche, H., Dupuis, S., Ben-David, Y., et al. (1998). Telomere elongation by hnRNP A1 and a derivative that interacts with telomeric repeats and telomerase. Nat. Genet. 19, 199-202.
10. Lee, C.K., Weaks, R.L., Johnson, G.A., et al. (2000). Effect of protease inhibitors and antioxidants on in-vitro survival of porcine primodial germ cells. Biol. Reprod. 63, 887-897.
11. Polyak, K., Xia, Y., Zweier, J.L., et al. (1997). A model for p53-induced apoptosis. Nature 389, 300-305.
12. Saito, H., Hammond, A.T., and Moses, R.E. (1995). The effect of low oxygen tension on the in vitro-replicative life span of human diploid fibroblast cells and their transformed derivatives. Exp. Cell Res. 217, 272-279.
13. Steinert, S., Shay, J.W., and Wright, W.E. (2000). Transient expression of human telomerase extends the life span of normal human fibroblasts. Biochem. Biophys. Res. Commun. 273, 1095-1098.
14. Vaziri, H., and Benchimol, S. (1998). Reconstitution of telomerase activity in normal human cells leads to elongation of telomeres and extended replicative life span. Curr. Biol. 8, 279-282.
15. Von Zglinicki, T., Burkle, A., and Krikwood, T.B. (2001). Stress, DNA damage and ageing - an integrative approach. Exp. Gerontol. 36, 1049-1062.
16. Yang, J., Chang, E., Cherry, A.M., et al. (1999). Human endothelial cell life extension by telomerase expression. J. Biol. Chem. 274, 26141-26148.