The Drosophila hairy RNA localization signal modulates the kinetics of cytoplasmic mRNA transport

EMBO Journal

Volumn 22, Issue 10, 2003, Pages 2484-2494

  Bullock, Simon L ^a   Zicha, Daniel ^a   Ish Horowicz, David ^a  

^a IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

Author keywords

BicD; Egl; mRNA localization; Secondary structure; Transport kinetics

Indexed keywords

DYNEIN ADENOSINE TRIPHOSPHATASE; MESSENGER RNA; MOLECULAR MOTOR;

3' UNTRANSLATED REGION; ANIMAL CELL; ARTICLE; BLASTODERM; CELL TYPE; COMPLEX FORMATION; CYTOPLASM; DROSOPHILA; KINETICS; MICROSCOPY; MICROTUBULE; MOLECULAR RECOGNITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN SECONDARY STRUCTURE; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; TRANSPORT KINETICS;

ANIMALS; BASE SEQUENCE; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CELL POLARITY; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; INSECT PROTEINS; MOLECULAR SEQUENCE DATA; MUTATION; NUCLEIC ACID CONFORMATION; PROTEIN TRANSPORT; REPRESSOR PROTEINS; RNA, MESSENGER; SEQUENCE ALIGNMENT;

ANIMALIA;

EID: 0037900898     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/cdg230     Document Type: Article

References (37)

1. Ainger, K., Avossa, D., Diana, A.S., Barry, C., Barbarese, E. and Carson, J.H. (1997) Transport and localization elements in myelin basic protein mRNA. J. Cell Biol., 138, 1077-1087.
2. Beverley, S.M. and Wilson, A.C. (1984) Molecular evolution in Drosophila and the higher Diptera II. A time scale for fly evolution. J. Mol. Evol., 21, 1-13.
3. Bullock, S.L. and Ish-Horowicz, D. (2001) Conserved signals and machinery for RNA transport in Drosophila oogenesis and embryogenesis. Nature, 414, 611-616.
4. Chartrand, P., Meng, X.H., Singer, R.H. and Long, R.M. (1999) Structural elements required for the localization of ASH1 mRNA and of a green fluorescent protein reporter particle in vivo. Curr. Biol., 9, 333-336.
5. Davis, I. and Ish-Horowicz, D. (1991) Apical localization of pair-rule transcripts requires 3′ sequences and limits protein diffusion in the Drosophila blastoderm embryo. Cell, 67, 927-940.
6. Ferrandon, D., Koch, I., Westhof, E. and Nüsslein-Volhard, C. (1997) RNA-RNA interaction is required for the formation of specific bicoid mRNA 3′ UTR-STAUFEN ribonucleoprotein particles. EMBO J., 16, 1751-1758.
7. Friedman, D.S. and Vale, R.D. (1999) Single-molecule analysis of kinesin motility reveals regulation by the cargo-binding tail domain. Nat. Cell Biol., 1, 293-297.
8. Gonzalez, I., Buonomo, S.B., Nasmyth, K. and von Ahsen, U. (1999) ASH1 mRNA localization in yeast involves multiple secondary structural elements and Ash1 protein translation. Curr. Biol., 9, 337-340.
9. Gross, S.P., Welte, M.A., Block, S.M. and Wieschaus, E.F. (2000) Dynein-mediated cargo transport in vivo. A switch controls travel distance. J. Cell Biol., 148, 945-956.
10. Gross, S.P., Welte, M.A., Block, S.M. and Wieschaus, E.F. (2002) Coordination of opposite-polarity microtubule motors. J. Cell Biol., 156, 715-724.
11. Hermann, T. and Patel, D.J. (1999) Stitching together RNA tertiary architectures. J. Mol. Biol., 294, 829-849.
12. Hoogenraad, C.C., Akhmanova, A., Howell, S.A., Dortland, B.R., De Zeeuw, C.I., Willemsen, R., Visser, P., Grosveld, F. and Galjart, N. (2001) Mammalian Golgi-associated Bicaudal-D2 functions in the dynein-dynactin pathway by interacting with these complexes. EMBO J., 20, 4041-4054.
13. Karcher, R.L., Deacon, S.W. and Gelfand, V.I. (2002) Motor-cargo interactions: the key to transport specificity. Trends Cell Biol., 12, 21-27.
14. Karlin-Mcginness, M., Serano, T.L. and Cohen, R.S. (1996) Comparative analysis of the kinetics and dynamics of K10, bicoid and oskar mRNA localization in the Drosophila oocyte. Dev. Genet., 19, 238-248.
15. Kloc, M., Zearfoss, N.R. and Etkin, L.D. (2002) Mechanisms of subcellular mRNA localization. Cell, 108, 533-544.
16. Lall, S., Francis-Lang, H., Flament, A., Norvell, A., Schupbach, T. and Ish-Horowicz, D. (1999) Squid hnRNP protein promotes apical cytoplasmic transport and localization of Drosophila pair-rule transcripts. Cell, 98, 171-180.
17. Leontis, N.B. and Westhof, E. (2001) Geometric nomenclature and classification of RNA base pairs. RNA, 7, 499-512.
18. Lück, R., Graf, S. and Steger, G. (1999) ConStruct: a tool for thermodynamic controlled prediction of conserved secondary structure. Nucleic Acids Res., 27, 4208-4217.
19. Macdonald, P.M. (1990) bicoid mRNA localization signal: phylogenetic conservation of function and RNA secondary structure. Development, 110, 161-171.
20. Macdonald, P.M. and Kerr, K. (1997) Redundant RNA recognition events in bicoid mRNA localization. RNA, 3, 1413-1420.
21. Macdonald, P.M. and Kerr, K. (1998) Mutational analysis of an RNA recognition element that mediates localization of bicoid mRNA. Mol. Cell. Biol., 18, 3788-3795.
22. Macdonald, P.M., Kerr, K., Smith, J.L. and Leask, A. (1993) RNA regulatory element BLE1 directs the early steps of bicoid mRNA localization. Development, 118, 1233-1243.
23. Mach, J.M. and Lehmann, R. (1997) An Egalitarian-BicaudalD complex is essential for oocyte specification and axis determination in Drosophila. Genes Dev., 11, 423-435.
24. Mathews, D.H., Sabina, J., Zuker, M. and Turner, D.H. (1999) Expanded sequence dependence of thermodynamic parameters improves prediction of RNA secondary structure. J. Mol. Biol., 288, 911-940.
25. Milliken, G.A. and Johnson, D.E. (1992) Analysis of Messy Data, Volume I: Designed Experiments. Chapman & Hall, New York, NY.
26. Moser, M.J., Holley, W.R., Chatterjee, A. and Mian, I.S. (1997) The proofreading domain of Escherichia coli DNA polymerase I and other DNA and/or RNA exonuclease domains. Nucleic Acids Res., 25, 5110-5118.
27. Oh, J. and Steward, R. (2001) Bicaudal-D is essential for egg chamber formation and cytoskeletal organization in Drosophila oogenesis. Dev. Biol., 232, 91-104.
28. Oh, J., Baksa, K. and Steward, R. (2000) Functional domains of the Drosophila bicaudal-D protein. Genetics, 154, 713-724.
29. Serano, T.L. and Cohen, R.S. (1995) A small predicted stem-loop structure mediates oocyte localization of Drosophila K10 mRNA. Development, 121, 3809-3818.
30. Shah, J.V., Flanagan, L.A., Janmey, P.A. and Leterrier, J.F. (2000) Bidirectional translocation of neurofilaments along microtubules mediated in part by dynein/dynactin. Mol. Biol. Cell, 11, 3495-3508.
31. Simmonds, A.J., dos Santos, G., Livne-Bar, I. and Krause, H.M. (2001) Apical localization of wingless transcripts is required for wingless signaling. Cell, 105, 197-207.
32. Suter, B., Romberg, L.M. and Steward, R. (1989) Bicaudal-D, a Drosophila gene involved in developmental asymmetry: localized transcript accumulation in ovaries and sequence similarity to myosin heavy chain tail domains. Genes Dev., 3, 1957-1968.
33. Swan, A., Nguyen, T. and Suter, B. (1999) Drosophila Lissencephaly-1 functions with Bic-D and dynein in oocyte determination and nuclear positioning. Nat. Cell Biol., 1, 444-449.
34. Welte, M.A., Gross, S.P., Postner, M., Block, S.M. and Wieschaus, E.F. (1998) Developmental regulation of vesicle transport in Drosophila embryos: forces and kinetics. Cell, 92, 547-557.
35. Wharton, R.P. and Struhl, G. (1989) Structure of the Drosophila BicaudalD protein and its role in localizing the posterior determinant nanos. Cell, 59, 881-892.
36. Wilkie, G.S. and Davis, I. (2001) Drosophila wingless and pair-rule transcripts localize apically by dynein-mediated transport of RNA particles. Cell, 105, 209-219.
37. Zuker, M., Mathews, D.H. and Turner, D.H. (1999) Algorithms and Thermodynamics for RNA Secondary Structure Prediction: A Practical Guide, RNA Biochemistry and Biotechnology. Kluwer Academic, Dordrecht, The Netherlands.