Dihydrobetulinic acid induces apoptosis in Leishmania donovani by targeting DNA topoisomerase I and II: Implications in antileishmanial therapy

Molecular Medicine

Volumn 9, Issue 1-2, 2003, Pages 26-36

  Chowdhury, Arnab Roy ^a   Mandal, Suparna ^a   Goswami, Anindya ^a   Ghosh, Monidipa ^a   Mandal, Labanya ^a   Chakraborty, Debabani ^a   Ganguly, Agneyo ^a   Tripathi, Gayatri ^a   Mukhopadhyay, Sibabrata ^a   Bandyopadhyay, Santu ^a   Majumder, Hemanta K ^a  

^a INDIAN INSTITUTE OF CHEMICAL BIOLOGY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

AGAROSE; ANTILEISHMANIAL AGENT; DIHYDROBETULINIC ACID; DNA; DNA TOPOISOMERASE; DNA TOPOISOMERASE (ATP HYDROLYSING); DNA TOPOISOMERASE INHIBITOR; MONOMER; UNCLASSIFIED DRUG;

AMASTIGOTE; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL ULTRASTRUCTURE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOPATHOGENIC EFFECT; DNA CLEAVAGE; DNA ISOLATION; DRUG EFFECT; DRUG ISOLATION; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME INHIBITION; HAMSTER; HISTOPATHOLOGY; IC 50; LEISHMANIA DONOVANI; LEISHMANIASIS; LIVER; MALE; MICROBIAL GROWTH; NONHUMAN; PRIORITY JOURNAL; PROMASTIGOTE; PULSED FIELD GEL ELECTROPHORESIS; SPLEEN; TRANSMISSION ELECTRON MICROSCOPY;

EID: 0037868155     PISSN: 10761551     EISSN: None     Source Type: Journal    
DOI: 10.1007/bf03402104     Document Type: Article

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