Modulations of nerve growth factor and Bcl-2 in ultraviolet-irradiated human epidermis

Journal of Cutaneous Pathology

Volumn 30, Issue 6, 2003, Pages 351-357

  Stefanato, Catherine M ^a,b   Yaar, Mina ^a   Bhawan, Jag ^a   Phillips, Tania J ^a   Kosmadaki, Maria G ^a   Botchkarev, Vladimir ^a   Gilchrest, Barbara A ^a  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Dermatopathology Section   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN G POLYCLONAL ANTIBODY; IMMUNOGLOBULIN G2A MONOCLONAL ANTIBODY; IMMUNOGLOBULIN KAPPA CHAIN MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY; NERVE GROWTH FACTOR; POLYCLONAL ANTIBODY; PROTEIN BCL 2; TYROSINASE RELATED PROTEIN 1; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CELL COUNT; CYTOPLASM; EPIDERMIS; EPIDERMIS CELL; ERYTHEMA; FEMALE; HUMAN; HUMAN EXPERIMENT; KERATINOCYTE; MELANOCYTE; NORMAL HUMAN; PROTEIN ANALYSIS; PROTEIN DETERMINATION; PROTEIN MODIFICATION; RADIATION DOSE; SIMULATION; SKIN BIOPSY; SKIN PROTECTION; SOLAR RADIATION; STAINING; TIME; ULTRAVIOLET RADIATION;

ADULT; CELL COUNT; EPIDERMIS; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; HUMANS; INTERFERON TYPE I; KERATINOCYTES; MELANOCYTES; MIDDLE AGED; NERVE GROWTH FACTOR; PREGNANCY PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; ULTRAVIOLET RAYS;

EID: 0037826939     PISSN: 03036987     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1600-0560.2003.00065.x     Document Type: Article

References (40)

1. Serri F, Cerimele D, Stefanato CM. Embriologia della pelle. In Giannetti A, ed. Trattato di dermatologia. Padova, Italia: Piccin, 2001; 1.
2. Gilchrest BA, Blog FB, Szabo G. Effects of aging and chronic sun exposure on melanocytes in human skin. J Invest Dermatol 1979; 73: 141.
3. Norris DA, Morelli JG, Fujita M. Melanocyte interactions in the skin. In Nordlund JJ, Boissy RE, Hearing VJ, King RA, Ortonne JP, eds. The pigmentary system - physiology and pathophysiology. New York, NY: Oxford University Press, Inc., 1998; 123.
4. Zhai S, Yaar M, Doyle SM, Gilchrest BA. Nerve growth factor rescues pigment cells from ultraviolet-induced apoptosis by upregulating BCL-2 levels. Exp Cell Res 1996; 224: 335.
5. Yaar M, Grossman K, Eller M, Gilchrest BA. Evidence for nerve growth factor-mediated paracrine effects in human epidermis. J Cell Biol 1991; 115: 821.
6. Di Marco E, Marchisio PC, Bondanza S, Franzi AT, Cancedda R, De Luca M. Growth-regulated synthesis and secretion of biologically active nerve growth factor by human keratinocytes. J Biol Chem 1991; 266: 21718.
7. Tron VA, Coughlin MD, Jang DE, Stanisz J, Sauder DN. Expression and modulation of nerve growth factor in murine keratinocytes (PAM 212). J Clin Invest 1990; 85: 1085.
8. Hachiya A, Kobayashi A, Ohuchi A, Takema Y, Imokawa G. The paracrine role of stem cell factor/c-kit signaling in the activation of human melanocytes in ultraviolet-B-induced pigmentation. J Invest Dermatol 2001; 116: 578.
9. Norris DA, Middleton MH, Whang K, Davis D, Duke R. The role of Bcl-2 and Fas in control of apoptosis in keratinocytes and melanocytes. J Invest Dermatol 1994; 103: 442.
10. Van den Oord JJ, Vandeghinste N, De Ley M, De Wolf-Peeters C. Bcl-2 expression in human melanocytes and melanocytic tumors. Am J Pathol 1994; 145: 294.
11. Klein-Parker HA, Warshawski L, Tron VA. Melanocytes in human skin express bcl-2 protein. J Cutan Pathol 1994; 21: 297.
12. Tsujimoto Y, Cossman J, Jaffe E, Croce CM. Involvement of the bcl-2 gene in human follicular lymphoma. Science 1985; 228: 1440.
13. Korsmeyer SJ. Bcl-2: an antidote to programmed cell death. Cancer Surv 1992; 15: 105.
14. Middleton MH, Duke R, Norrris D. Different patterns of necrosis and observed in human melanocytes and keratinocytes. J Invest Dermatol 1995; 104: 572.
15. Norris DA. Differential control of cell death in the skin. Arch Dermatol 1995; 131: 945.
16. Del Marmol V, Beermann F. Tyrosinase and related proteins in mammalian pigmentation. FEBS Lett 1996; 381: 165.
17. Thomson TM, Real FX, Murakami S, Cordan-Carlo C, Old LJ, Houghton AN. Differentiation antigens of melanocytes and melanoma: analysis of melanosome and cell surface markets of human pigmented cells with monoclonal antibodies. J Invest Dermatol 1988; 90: 459.
18. Tai T, Eisinger M, Ogata S, Lloyd KO. Glycoproteins as differentiation markers in human malignant melanoma and melanocytes. Cancer Res 1983; 43: 2773.
19. Vijayasaradhi S, Houghton AN. Purification of an autoantigenic 75-kDa human melanosomal glycoprotein. Int J Cancer 1991; 47: 298.
20. Bhawan J. Mel-5: a novel antibody for differential diagnosis of epidermal pigmented lesions of the skin in paraffin-embedded sections. Melanoma Res 1997; 7: 43.
21. Phillips TJ, Bhawan J, Yaar M, Bello Y, LoPiccolo D, Nash JF. Effect of daily versus intermittent sunscreen application on solar simulated UV radiation-induced skin response in humans. J Am Acad Dermatol 2000; 43: 610.
22. Botchkareva NV, Khlgatian M, Longley BJ, Botchkarev VA, Gilchrest BA. SCF/c-kit signaling is required for cyclic regeneration of the hair pigmentation unit. FASEB J 2001; 15: 645.
23. Pincelli C, Yaar M. Nerve growth factor: its significance in cutaneous biology. J Invest Dermatol Symp Proc 1997; 2: 31.
24. Ayer-LeLievre C, Olson L, Ebendal T, Seiger A, Persson H. Expression of the beta-nerve growth factor gene in hippocampal neurons. Science 1988; 240: 1339.
25. Hara M, Toyoda M, Yaar M, et al. Innervation of melanocytes in human skin. J Exp Med 1996; 184: 1385.
26. Levi-Montalcini R. The nerve growth factor 35 years later. Science 1987; 237: 1154.
27. Mayer S, Eller MS, Gilchrest BA. The SOS response in human skin. Curr Probl Dermatol 2001; 13: 153.
28. Khlgatian MK, Hadshiew IM, Asawanonda P, et al. Tyrosinase gene expression is regulated by p53. J Invest Dermatol 2002; 118: 126.
29. Leccia MT, Yaar M, Allen N, Gleason M, Gilchrest BA. Solar simulated irradiation modulates gene expression and activity of antioxidant enzymes in cultured human dermal fibroblasts. Exp Dermatol 2001; 10: 272.
30. Diamond J, Holmes M, Coughlin M. Endogenous NGF and nerve impulses regulate the collateral sprouting of sensory axons in the skin of the adult rat. J Neurosci 1992; 12: 1454.
31. Pincelli C, Marconi A. Autocrine nerve growth factor in human keratinocytes. J Dermatol Sci 2000; 22: 71.
32. Cario-André M, Pain C, Gall Y, Ginestar J, Nikaido O, Taïeb A. Studies on epidermis reconstructed with and without melanocytes: melanocytes prevent sunburn cell formation but not appearance of DNA damaged cells in fair-skinned caucasians. J Invest Dermatol 2000; 115: 193.
33. Gilchrest BA, Eller MS, Geller AC, Yaar M. The pathogenesis of melanoma induced by ultraviolet radiation. N Engl J Med 1999; 340: 1341.
34. McGill GG, Horstmann M, Widlund HR, et al. Bcl2 regulation by the melanocyte master regulator Mitf modulates lineage survival and melanoma cell viability. Cell 2002; 109: 707.
35. Sellheyer K, Krahl D, Ratech H. Distribution of Bcl-2 and Bax in embryonic and fetal human skin: antiapoptotic and proapoptotic proteins are differentially expressed in developing skin. Am J Dermatopathol 2001; 23: 1.
36. Bayerl C, Taake S, Moll I, Jung EG. Characterization of sunburn cells after exposure to ultraviolet light. Photodermatol Photoimmunol Photomed 1995; 11: 149.
37. Nylander K, Bourdon JC, Bray SE, et al. Transcriptional activation of tyrosinase and TRP-1 by p53 links UV irradiation to the protective tanning response. J Pathol 2000; 190: 39.
38. Kulms D, Schwarz T. Molecular mechanisms of UV-induced apoptosis. Photodermatol Photoimmunol Photomed 2000; 16: 195.
39. Kawaguchi Y, Mori N, Nakayama A. Kit+ melanocytes seem to contribute to melanocyte proliferation after UV exposure as precursor cells. J Invest Dermatol 2001; 116: 920.
40. Maeda T, Hao C, Tron VA. Ultraviolet light (UV) regulation of the TNF family decoy receptors DcR2 and DcR3 in human keratinocytes. J Cutan Med Surg 2001; 5: 294.