Studies on epidermis reconstructed with and without melanocytes: Melanocytes prevent sunburn cell formation but not appearance of DNA damaged cells in fair-skinned caucasians

Journal of Investigative Dermatology

Volumn 115, Issue 2, 2000, Pages 193-199

  Cario André, Muriel ^c   Pain, Catherine ^c   Gall, Yvon ^a   Ginestar, José ^a   Nikaido, Osamu ^b   Täeb, Alain ^c  

^a INSTITUT DE RECHERCHE PIERRE FABRE   (France)

^b Division of Radiation Biology   (Japan)

^c Kanawaza University ^*

Author keywords

Photoprotection; Ultraviolet

Indexed keywords

ARTICLE; CAUCASIAN; DNA DAMAGE; HUMAN; HUMAN TISSUE; MELANOCYTE; PRIORITY JOURNAL; SUNBURN; ULTRAVIOLET B RADIATION;

EID: 0033874307     PISSN: 0022202X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1747.2000.00007.x     Document Type: Article

References (45)

1. Comparison of the response of human melanocytes with different melanin contents to ultraviolet B radiation
2. Characterization of sunburn cells after exposure to ultraviolet light
3. Epidermal proliferation but not the quantity of DNA photodamage is correlated with UV-Induced mouse skin carcinogenesis
4. Ex vivo reconstruction of the epidermis with melanocytes and the influence of UVB
5. Chimeric human epidermal reconstructs to study the role of melanocyte and keratinocytes in pigmentation and photoprotection
6. Formation of UV-induced apoptosis relates to the cell cycle
7. Sunburn cell: Factors involved in its formation
8. Comparison of melanocytes and keratinocytes in ultraviolet-induced DNA damage per minimum erythema dose sunlight: Applicability of ultraviolet action spectra for risk estimates
9. Scavenger effect of vitamin E and derivatives on free radicals generated by photoirradiated pheomelanin
10. Variation in excision repair of UVB-induced pyrimidine dimers in DNA of human skin in situ
11. Acute effects of ultraviolet radiation in the skin
12. Open questions in photobiology III. Melanin and photoprotection
13. The human sunburn reaction: Histologic and biochemical studies
14. Two pathways for induction of apoptosis by ultraviolet radiation in cultures human keratinocytes
15. Sunscreens prevent sunburn cell formation in human skin
16. Effects of hydroquinone on the synthesis of pheomelanins
17. Eumelanin and pheomelanin contents of human epidermis and cultured melanocytes
18. Long-term follow-up study of changes in lipid peroxide levels and the activity of superoxide dismutase, catalase and glutathione peroxidase in mouse skin after acute and chronic UV irradiation
19. The role of melanocytes in the repair of UV related DNA Damage in keratinocytes
20. Supranuclear melanin caps reduce ultraviolet induced DNA photoproducts in human epidermis
21. Differentiation-dependent p53 regulation of nucleotide excision repair in keratinocytes
22. Epidermal ornithine decarboxylase, polyamines, cell proliferation and tumor promotion
23. Ultraviolet light induces human epidermal ornithine decarboxylase activity
24. A comparative study of the physical and chemical properties of melanins isolated from human black and red hair
25. Repair of pyrimidine (6-4) pyrimidone photoprodncts in mouse skin
26. Simultaneous establishment of monoclonal antibodies specific for either cyclobutane pyrimidine dimer or (6-4) photoproduct from the same mouse immunized with ultraviolet-irradiated DNA
27. Induction and repair of UVB-induced cyclobutane pyrimidine dimers and (6-4) photoproducts in organ-cultured normal human skin
28. Ultraviolet-induced individual cell keratinization
29. Effects of single-dose ultraviolet radiation on skin superoxide dismutase, catalase and xanthine oxidase in hairless mice
30. Apoptosis: The skin from a new perspective
31. Ultraviolet light induces expression of p53 and p21 in human skin: Effect of sunscreen and constitutive p21 expression in skin appendages
32. Detection of active UV-photoproduct repair in monkey skin m vivo by quantitative immunohistochemistry
33. Comparative removal of pyrimidine dimers from human epidermal keratinocytes in vivo and in vitro
34. Strand-specific removal of cyclobutane pyrimidine dimers from p53 gene in the epidermis of UVB-irradiated hairless mice
35. Stopped for repairs
36. Dual role of melanins and melanin precursors as photoprotective and phototoxic agents: Inhibition of ultraviolet radiation induced lipid peroxidation
37. Pyrimidine dimer induction and repair in cultured human skin keratinocytes or melanocytes after irradiation with monochromatic ultraviolet radiation
38. Ultraviolet B-induced apoptosis of keratinocytes: Evidence for partial involvement of tumor-necrosis factor-alpha in the formation of sunburn cells
39. Pentoxifylline reduces the formation of sunburn cells
40. Repair by human cell extracts of single (6-4) and cyclobutane thymine-thymine photoproducts in DNA
41. Immunohistochemical localization of ornithine decarboxylase in human skin
42. Sunscreens and T4N5 liposomes differ in their ability to protect against ultraviolet-induced sunburn cell formation, alterations of dendritic epidermal cells, and local suppression of contact hypersensitivity
43. Cultured human melanocytes from black and white donors have different sunlight and ultraviolet A radiation sensitivities
44. The sunburn cell
45. The in situ repair kinetics of epidermal thymine dimers and 6-4 photoproducts in human skin type I and II