Identification of a phosphothionate analogue of lysophosphatidic acid (LPA) as a selective agonist of the LPA3 receptor

Journal of Biological Chemistry

Volumn 278, Issue 14, 2003, Pages 11962-11969

  Hasegawa, Yutaka ^a   Erickson, James R ^b,e   Goddard, Graham J ^b,f   Yu, Shuangxing ^a   Liu, Shuying ^a   Cheng, Kwai Wa ^a   Eder, Astrid ^a   Bandoh, Koji ^c   Aoki, Junken ^c   Jarosz, Renata ^d   Schrier, Andrew D ^d   Lynch, Kevin R ^d   Mills, Gordon B ^a   Fang, Xianjun ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b LXR Biotechnology   (United States)

^c UNIVERSITY OF TOKYO   (Japan)

^d UNIVERSITY OF VIRGINIA HEALTH SYSTEM   (United States)

^e AGY Therapeutics Inc   (United States)

^f GENENTECH INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; CELLS; PROTEINS; YEAST;

LYSOPHOSPHATIDIC ACID (LPA);

PHOSPHOLIPIDS;

1 OLEOYL 2 O METHYL GLYCEROPHOSPHOTHIONATE; CALCIUM; ESTER; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); LYSOPHOSPHATIDIC ACID; LYSOPHOSPHATIDIC ACID 1 RECEPTOR; LYSOPHOSPHATIDIC ACID 2 RECEPTOR; LYSOPHOSPHATIDIC ACID 3 RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; PHEROMONE; PHOSPHOROTHIOIC ACID DERIVATIVE; RECEPTOR SUBTYPE; UNCLASSIFIED DRUG; 1 OLEOYL 2 O METHYL RAC GLYCEROPHOSPHOTHIONATE; 1-OLEOYL-2-O-METHYL-RAC-GLYCEROPHOSPHOTHIONATE; CELL SURFACE RECEPTOR; G PROTEIN COUPLED RECEPTOR; LYSOPHOSPHATIDIC ACID RECEPTOR; LYSOPHOSPHOLIPID; MITOGENIC AGENT; PHOSPHATIDIC ACID;

ANIMAL CELL; ARTICLE; BINDING ASSAY; CALCIUM CELL LEVEL; CALCIUM MOBILIZATION; CELL STRAIN; CONTROLLED STUDY; EMBRYO; FIBROBLAST; HORMONE RESPONSE; HUMAN; HUMAN CELL; INSECT CELL; MAMMAL CELL; MITOGENICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; YEAST CELL; ANIMAL; ARMYWORM; C3H MOUSE; CELL STRAIN 3T3; CHEMISTRY; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; DRUG POTENTIATION; KIDNEY; MAMMAL; METABOLISM; MOUSE; SIGNAL TRANSDUCTION; YEAST;

ANIMALIA; INSECTA; MAMMALIA;

3T3 CELLS; ANIMALS; CALCIUM; HUMANS; KIDNEY; LYSOPHOSPHOLIPIDS; MAMMALS; MICE; MICE, INBRED C3H; MITOGENS; PHOSPHATIDIC ACIDS; RECEPTORS, CELL SURFACE; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, LYSOPHOSPHATIDIC ACID; SIGNAL TRANSDUCTION; SPODOPTERA; THIOPHOSPHORIC ACID ESTERS; YEASTS;

EID: 0037809241     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M209168200     Document Type: Article

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