Lysophosphatidic acid enhances contractility of isolated airway smooth muscle

Journal of Applied Physiology

Volumn 83, Issue 4, 1997, Pages 1216-1222

  Toews, M L ^a   Ustinova, E E ^b   Schultz, H D ^b  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^b UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

Bronchoconstriction

Indexed keywords

ADENYLATE CYCLASE ACTIVATOR; FORSKOLIN; LYSOPHOSPHATIDIC ACID; METHACHOLINE; MUSCARINIC AGENT; POTASSIUM CHLORIDE; SEROTONIN; SUBSTANCE P;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; ASTHMA; CAT; CONCENTRATION RESPONSE; CONTROLLED STUDY; NONHUMAN; PRIORITY JOURNAL; RABBIT; RESPIRATORY TRACT MUCOSA; SIGNAL TRANSDUCTION; SMOOTH MUSCLE CONTRACTILITY; SPECIES DIFFERENTIATION; STIMULUS RESPONSE; TRACHEA MUSCLE;

EID: 0030810597     PISSN: 87507587     EISSN: None     Source Type: Journal    
DOI: 10.1152/jappl.1997.83.4.1216     Document Type: Article

References (29)

1. Beckmann, J. D., D. J. Romberger, S. I. Rennard, and J. R. Spurzem. Induction of bovine bronchial epithelial cell filopodia by tetradecanoyl phorbol acetate, calcium ionophore, and lysophosphatidic acid. J. Cell. Physiol. 164: 123-131, 1995.
2. Cerutis, D. R., M. Nogami, J. L. Anderson, J. D. Churchill, D. J. Romberger, S. I. Rennard, and M. L. Toews. Lysophosphatidic acid and epidermal growth factor stimulate mitogenesis in human airway smooth muscle cells. Am. J. Physiol. 273 (Lung Cell. Mol. Physiol. 17): L10-L15, 1997.
3. Chilton, F. H., F. J. Averill, W. C. Hubbard, A. N. Fonteh, M. Triggiani, and M. C. Liu. Antigen-induced generation of lysophospholipids in human airways. J. Exp. Med. 183: 2235-2245, 1996.
4. Eichholtz, T., K. Jalink, I. Fahrenfort, and W. H. Moolenaar. The bioactive phospholipid lysophosphatidic acid is released from activated platelets. Biochem. J. 291: 677-680, 1993.
5. Fukami, K., and T. Takenawa. Phosphatidic acid that accumulates in platelet-derived growth factor-stimulated BALB/c 3T3 cells is a potential mitogenic signal. J. Biol. Chem. 267: 10988-10993, 1992.
6. Guo, Z., K. Liliom, D. J. Fischer, I. C. Bathurst, L. D. Tomei, M. C. Kiefer, and G. Tigyi. Molecular cloning of a high-affinity receptor for the growth factor-like lipid mediator lysophosphatidic acid from Xenopus oocytes. Proc. Natl. Acad. Sci. USA 93: 14367-14372, 1996.
7. Hecht, J. H., J. A. Weiner, S. R. Post, and J. Chun. Ventricular zone gene-1 (vzg-1) encodes a lysophosphatidic acid receptor expressed in neurogenic regions of the developing cerebral cortex. J. Cell Biol. 135: 1071-1083, 1996.
8. Hirst, S. J., and C. H. C. Twort. The proliferative response of airway smooth muscle. Clin. Exp. Allergy 22: 907-915, 1992.
9. Hollenberg, M. D. Tyrosine kinase pathways and the regulation of smooth muscle contractility. Trends Pharmacol. Sci. 15: 108-114, 1994.
10. Koschel, K., and P. W. L. Tas. Lysophosphatidic acid reverts the β-adrenergic agonist-induced morphological response in C6 rat glioma cells. Exp. Cell Res. 206: 162-166, 1993.
11. Kreps, D. M., S. M. Whittle, J. M. Hoffman, and M. L. Toews. Lysophosphatidic acid mimics serum-induced sensitization of cAMP accumulation. FASEB J. 7: 1376-1380, 1993.
12. Moolenaar, W. H. Lysophosphatidic acid, a multifunctional phospholipid messenger. J. Biol. Chem. 270: 12949-12952, 1995.
13. Moolenaar, W. H. Lysophosphatidic acid signaling. Curr. Biol. 7: 203-210, 1995.
14. Nogami, M., S. M. Whittle, D. J. Romberger, S. I. Rennard, and M. L. Toews. Lysophosphatidic acid regulation of cAMP accumulation in cultured human airway smooth muscle cells. Mol. Pharmacol. 48: 766-773, 1995.
15. Panettieri, R. A., P. A. Yadvish, A. M. Kelly, N. A. Rubinstein, and M. I. Kotlikoff. Histamine stimulates proliferation of airway smooth muscle and induces c-fos expression. Am. J. Physiol. 259 (Lung Cell. Mol. Physiol. 3): L365-L371, 1990.
16. Patel, P., H. Itoh, K. Dederis, and M. D. Hollenberg. Contraction of guinea pig trachea by epidermal growth factor-urogastrone. Can. J. Physiol. Pharmacol. 66: 1308-1312, 1988.
17. Ridley, A. J., and A. Hall. The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors. Cell 70: 389-399, 1992.
18. Romberger, D. J., P. Pladsen, Y. Adachi, S. I. Rennard, M. Nogami, and M. Toews. Lysophosphatidic acid stimulates airway epithelial cell fibronectin release (Abstract). Am. J. Respir. Crit. Care Med. 149: A995, 1994.
19. 2-terminal kinase groups of mitogen-activated protein kinases. J. Biol. Chem. 271: 5750-5754, 1996.
20. Stewart, A. G., P. R. Tomlinson, and J. Wilson. Airway wall remodeling in asthma: a novel target for the development of antiasthma drugs. Trends Pharmacol. Sci. 14: 275-279, 1993.
21. Tigyi, G., L. Hong, M. Yakuba, H. Parfenova, M. Shibata, and C. Leffler. Lysophosphatidic acid alters cerebrovascular reactivity in piglets. Am. J. Physiol. 268 (Heart Circ. Physiol. 37): H2048-H2055, 1995.
22. Tigyi, G., and R. Miledi. Lysophosphatidates bound to serum albumin activate membrane currents in Xenopus oocytes and neurite retraction in PC12 pheochromocytoma cells. J. Biol. Chem. 267: 21360-21367, 1992.
23. Toews, M. L., E. E. Ustinova, and H. D. Schultz. Lysophosphatidic acid potentiates cholinergic contraction of isolated airway smooth muscle (Abstract). FASEB J. 9: A697, 1995.
24. Tokumura, A., K. Fukuzawa, and H. Tsukatani. Effects of synthetic and natural lysophosphatidic acid on the arterial blood pressure of different animal species. Lipids 13: 572-574, 1978.
25. Tokumura, A., K. Fukuzawa, and H. Tsukatani. Contractile actions of lysophosphatidic acids with a chemically-defined fatty acyl group on longitudinal muscle from guinea-pig ileum. J. Pharm. Pharmacol. 34: 514-516, 1982.
26. Tokumura, A., K. Fukuzawa, S. Yamada, and H. Tsukatani. Stimulatory effect of lysophosphatidic acids on uterine smooth muscles of non-pregnant rats. Arch. Int. Pharmacodyn. Ther. 245: 74-83, 1980.
27. Tokumura, A., M. Iimori, Y. Nishioka, M. Kitahara, M. Sakashita, and S. Tanaka. Lysophosphatidic acids induce proliferation of cultured vascular smooth muscle cells from rat aorta. Am. J. Physiol. 267 (Cell Physiol. 36): C204-C210, 1994.
28. Tokumura, A., N. Yube, H. Fujimoto, and H. Tsukatani. Lysophosphatidic acids induce contraction of rat isolated colon by two different mechanisms. J. Pharm. Pharmacol. 43: 774-778, 1991.
29. Wiggs, B. R., C. Bosken, P. D. Pare, A. James, and J. C. Hogg. A model of airway narrowing in asthma and in chronic obstructive pulmonary disease. Am. Rev. Respir. Dis. 145: 1251-1258, 1992.