Modelling the bacterial chemotaxis receptor complex

Novartis Foundation Symposium

Volumn 247, Issue , 2002, Pages 162-181

  Shimizu, Thomas Simon ^a   Bray, Dennis ^a   Hinch, ^b   Subramaniam, ^b  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOTAXIS METHYLTRANSFERASE; LIGAND; METHYLTRANSFERASE;

BACTERIAL PHENOMENA AND FUNCTIONS; BIOLOGICAL MODEL; CHEMOTAXIS; COMPUTER PROGRAM; METABOLISM; PHENOTYPE; PHYSIOLOGY; REVIEW; SIGNAL TRANSDUCTION; THERMODYNAMICS;

BACTERIAL PHYSIOLOGY; CHEMOTAXIS; LIGANDS; METHYLTRANSFERASES; MODELS, BIOLOGICAL; PHENOTYPE; SIGNAL TRANSDUCTION; SOFTWARE; THERMODYNAMICS;

EID: 0037805567     PISSN: None     EISSN: None     Source Type: Book Series    
DOI: None     Document Type: Conference Paper

References (30)

1. Alon U, Surette MG, Barkai N, Leibler S 1999 Robustness in bacterial chemotaxis. Nature 397:168-171
2. Barkai N, Leibler S 1997 Robustness in simple biochemical networks. Nature 387:913-917
3. Bass RB, Coleman MD, Falke JJ 1999 Signaling domain of the aspartate receptor is a helical hairpin with a localized kinase docking surface: cysteine and disulfide scanning studies. Biochemistry 38:9317-9327
4. Berg HC, Purcell EM 1977 Physics of chemoreception. Biophys J 20:193-219
5. Berg HC, Tedesco PM 1975 Transient response to chemotactic stimuli in Escherichia coli. Proc Natl Acad Sci USA 72:3235-3239
6. Bilwes AM, Alex LA, Crane BR, Simon MI 1999 Structure of CheA, a signal-transducing histidine kinase. Cell 96:131-141
7. Borkovich KA, Simon MI 1990 The dynamics of protein phosphorylation in bacterial chemotaxis. Cell 63:1339-1348
8. Bray D, Bourret RB 1995 Computer analysis of the binding reactions leading to a transmembrane receptor-linked multiprotein complex involved in bacterial chemotaxis. Mol Biol Cell 6:1367-1380
9. Bray D, Bourret RB, Simon MI 1993 Computer simulation of the phosphorylation cascade controlling bacterial chemotaxis. Mol Biol Cell 4:469-482
10. Bray D, Levin MD, Morton-Firth CJ 1998 Receptor clustering as a mechanism to control sensitivity. Nature 393:85-88
11. Bren A, Eisenbach M 2000 How signals are heard during bacterial chemotaxis: protein-protein interactions in sensory signal propagation. J Bacteriol 182:6865-6873
12. Cluzel P, Surette M, Leibler S 2000 An ultrasensitive bacterial motor revealed by monitoring signaling proteins in single cells. Science 287:1652-1655
13. Duke TA, Bray D 1999 Heightened sensitivity of a lattice of membrane receptors. Proc Natl Acad Sci USA 96:10104-10108
14. Falke JJ, Bass RB, Butler SL, Chervitz SA, Danielson MA 1997 The two component signaling pathway of bacterial chemotaxis: A molecular view of signal transduction by receptors, kinases, and adaptation enzymes. Annu Rev Cell Dev Biol 13:457-512
15. Gegner JA, Graham DR, Roth AF, Dahlquist FW 1992 Assembly of an MCP receptor, CheW, and kinase CheA complex in the bacterial chemotaxis signal transduction pathway. Cell 70:975-982
16. Kim KK, Yokota H, Kim SH 1999 Four-helical-bundle structure of the cytoplasmic domain of a serine chemotaxis receptor. Nature 400:787-792
17. Levin MD, Morton-Firth CJ, Abouhamad WN, Bourret RB, Bray D 1998 Origins of individual swimming behavior in bacteria. Biophys J 74:175-181
18. Levin MD, Shimizu TS, Bray D 2002 Binding and diffusion of CheR molecules within a cluster of membrane receptors. Biophys J 82:1809-1817
19. Li J, Li G, Weis RM 1997 The serine chemoreceptor from Escherichia coli is methylated through an inter-dimer process. Biochemistry 36:11851-11857
20. Liu J, Parkinson JS 1991 Genetic evidence for interaction between CheW and Tsr proteins during chemoreceptor signaling by Escherichia coli. J Bacteriol 173:4941-4951
21. Liu Y, Levit M, Lurz R, Surette MG, Stock JB 1997 Receptor-mediated protein kinase activation and the mechanism of transmembrane signaling in bacterial chemotaxis. EMBO J 16:7231-7240
22. Lupas A, Stock J 1989 Phosphorylation of an N-terminal regulatory domain activates the CheB methylesterase in bacterial chemotaxis. J Biol Chem 264:17337-17342
23. Maddock JR, Shapiro L 1993 Polar location of the chemoreceptor complex in the Escherichia coli cell. Science 259:1717-1723
24. Mesibov R, Ordal GW, Adler J 1973 The range of attractant concentrations for bacterial chemotaxis and the threshold and size of response over this range. Weber law and related phenomenon. J Gen Physiol 62:203-223
25. Morton-Firth CJ 1998 Stochastic simulation of cell signalling pathways. PhD thesis, University of Cambridge, Cambridge, UK
26. Morton-Firth CJ, Bray D 1998 Predicting temporal fluctuations in an intracellular signalling pathway. J Theor Biol 192:117-128
27. Morton-Firth CJ, Shimizu TS, Bray D 1999 A free-energy-based stochastic simulation of the Tar receptor complex. J Mol Biol 286:1059-1074
28. Segall JE, Block SM, Berg HC 1986 Temporal comparisons in bacterial chemotaxis. Proc Natl Acad Sci USA 83:8987-8991
29. Shimizu TS, Le Novere N, Levin MD, Beavil AJ, Sutton BJ, Bray D 2000 Molecular model of a lattice of signalling proteins involved in bacterial chemotaxis. Nat Cell Biol 2:792-796
30. Simms SA, Subbaramaiah K 1991 The kinetic mechanism of S-adenosyl-L-methionine: glutamylmethyltransferase from Salmonella typhimurium. J Biol Chem 266:12741-12746