Binding and diffusion of CheR molecules within a cluster of membrane receptors

Biophysical Journal

Volumn 82, Issue 4, 2002, Pages 1809-1817

  Levin, Matthew D ^a   Shimizu, Thomas S ^a   Bray, Dennis ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

MEMBRANE RECEPTOR; METHYLTRANSFERASE;

ADAPTATION; ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; CLUSTER ANALYSIS; DIFFUSION; ESCHERICHIA COLI; GEOMETRY; METHYLATION; MOLECULAR DYNAMICS; RECEPTOR BINDING; STOCHASTIC MODEL;

ESCHERICHIA COLI; HYLOBATES SP.;

EID: 0036220793     PISSN: 00063495     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-3495(02)75531-8     Document Type: Article

References (51)

1. Bacterial tactic responses
2. Efficient adaptational demethylation of chemoreceptors requires the same enzyme-docking site as efficient methylation
3. Location of the receptor-interaction site on CheB, the methylesterase response regulator of bacterial chemotaxis
4. Signaling domain of the aspartate receptor is a helical hairpin with a localized kinase docking surface: Cysteine and disulfide scanning studies
5. Physics of chemoreception
6. Demethylation of bacterial chemoreceptors is inhibited by attractant stimuli in the complete absence of the regulatory domain of the demethylating enzyme
7. The configuration of random polypeptide chains. I. Experimental results
8. How signals are heard during bacterial chemotaxis: Protein-protein interactions in sensory signal propagation
9. Kinetics of desolvation-mediated protein-protein binding
10. Molecular-cloning of chemotaxis genes and overproduction of gene-products in the bacterial sensing system
11. Crystal structure of the chemotaxis receptor methyltransferase CheR suggests a conserved structural motif for binding S-adenosylmethionine
12. Chemotaxis receptor recognition by protein methyltransferase CheR
13. High local protein concentrations at promoters: Strategies in prokaryotic and eukaryotic cells
14. The two-component signaling pathway of bacterial chemotaxis: A molecular view of signal transduction by receptors, kinases, and adaptation enzymes
15. Transmembrane signaling in bacterial chemoreceptors
16. High- and low-abundance chemoreceptors in Escherichia coli: Differential activities associated with closely related cytoplasmic domains
17. Enhanced function conferred on low-abundance chemoreceptor Trg by a methyltransferase-docking site
18. Assembly of an MCP receptor, CheW, and kinase CheA complex in the bacterial chemotaxis signal transduction pathway
19. Evolutionary conservation of methyl-accepting chemotaxis protein location in Bacteria and Archaea
20. Sensory transduction in bacterial chemotaxis
21. Biophysical and molecular mechanisms of Shaker potassium channel inactivation
22. Four-helical-bundle structure of the cytoplasmic domain of a serine chemotaxis receptor
23. Theory for ligand rebinding at cell membrane surfaces
24. Molecular evolution of the C-terminal cytoplasmic domain of a superfamily of bacterial receptors involved in taxis
25. Methylation of the Escherichia coli chemotaxis receptors: Intra- and interdimer mechanisms
26. STOCHSIM: Modelling of stochastic biomolecular processes
27. The serine chemoreceptor from Escherichia coli is methylated through an inter-dimer process
28. Receptor-mediated protein kinase activation and the mechanism of transmembrane signaling in bacterial chemotaxis
29. Polar location of the chemoreceptor complex in the Escherichia coli cell
30. Motility and chemotaxis of filamentous cells of Escherichia coli
31. Bacterial chemotaxis signaling complexes: Formation of a CheA/CheW complex enhances autophosphorylation and affinity for CheY
32. Predicting temporal fluctuations in an intracellular signalling pathway
33. Chemotaxis receptors: A progress report on structure and function
34. Kinetics of protein-protein association by Brownian dynamics computer simulation
35. Chemotactic adaptation is altered by changes in the carboxy-terminal sequence conserved among the major methyl-accepting chemoreceptors
36. Receptor interactions through phosphorylation and methylation pathways in bacterial chemotaxis
37. Assembly and function of a quaternary signal transduction complex monitored by surface plasmon resonance
38. Interactions between the methylation sites of the Escherichia coli aspartate receptor mediated by the methyltransferase
39. Molecular model of a lattice of signalling proteins involved in bacterial chemotaxis
40. The aspartate chemoreceptor Tar is effectively methylated by binding to the methyltransferase mainly through hydrophobic interaction
41. Multiple forms of the CheB methylesterase in bacterial chemosensing
42. Purification and characterization of the S-adenosylmethionine: Glutamyl methyltransferase that modifies membrane chemoreceptor proteins in bacteria
43. The kinetic mechanism of S-adenosyl-L-methionine: Glutamylmethyltransferase from Salmonella typhimurium
44. Kinetics of receptor modification: The multiply methylated aspartate receptors involved in bacterial chemotaxis
45. + channel inactivation domain
46. Relaxation kinetics of biological dimer adsorption models
47. Chimeric chemoreceptors in Escherichia coli: Signaling properties of Tar-Tap and Tap-Tar hybrids
48. The Q-linker: A class of interdomain sequences found in bacterial multidomain regulatory proteins
49. The receptor binding site for the methyltransferase of bacterial chemotaxis is distinct from the sites of methylation
50. The superfamily of chemotaxis transducers: From physiology to genomics and back