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Volumn 24, Issue 3, 2003, Pages 409-417

Arrest of apoptosis in auditory neurons: Implications for sensorineural preservation in cochlear implantation

Author keywords

Aptoptosis; Auditory neurons; c jun; Cochlear implantation; Inhibitors; Otoprotection; Stress kinase pathway

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; CISPLATIN; CURCUMIN; JANUS KINASE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR AP 1;

EID: 0037799359     PISSN: 15317129     EISSN: None     Source Type: Journal    
DOI: 10.1097/00129492-200305000-00011     Document Type: Article
Times cited : (63)

References (52)
  • 1
    • 0015383455 scopus 로고
    • Apoptosis: A basic biologic phenomenon with wide-ranging implications in tissue kinetics
    • Kerr JF, Wyllie AH, Currie AR. Apoptosis: a basic biologic phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer 1972;26:239-57.
    • (1972) Br J Cancer , vol.26 , pp. 239-257
    • Kerr, J.F.1    Wyllie, A.H.2    Currie, A.R.3
  • 2
    • 12644293785 scopus 로고    scopus 로고
    • Use of organotypic cultures of Corti's organ to study the protective effects of antioxidant molecules on cisplatin-induced damaged of auditory hair cells
    • Kopke RD, Liu W, Gabaizadeh R, et al. Use of organotypic cultures of Corti's organ to study the protective effects of antioxidant molecules on cisplatin-induced damaged of auditory hair cells. Am J Otol 1997;18:559-71.
    • (1997) Am J Otol , vol.18 , pp. 559-571
    • Kopke, R.D.1    Liu, W.2    Gabaizadeh, R.3
  • 3
    • 0022657044 scopus 로고
    • Modification of cisplatin toxicity by antioxidants
    • Sugihara K, Gemba M. Modification of cisplatin toxicity by antioxidants. Jpn J Pharmacol 1986;40:353-5.
    • (1986) Jpn J Pharmacol , vol.40 , pp. 353-355
    • Sugihara, K.1    Gemba, M.2
  • 4
    • 0023256801 scopus 로고
    • Effect of cisplatin on in vitro production of lipid peroxides in rat kidney cortex
    • Sugihara K, Nakano S, Gemba M. Effect of cisplatin on in vitro production of lipid peroxides in rat kidney cortex. Jpn J Pharmacol 1987;44:71-6.
    • (1987) Jpn J Pharmacol , vol.44 , pp. 71-76
    • Sugihara, K.1    Nakano, S.2    Gemba, M.3
  • 5
    • 0023720156 scopus 로고
    • Cisplatin-induced lipid peroxidation and decrease of gluconeogenesis in rat kidney cortex: Different effects of antioxidants and radical scavengers
    • Hannemann J, Baumann K. Cisplatin-induced lipid peroxidation and decrease of gluconeogenesis in rat kidney cortex: different effects of antioxidants and radical scavengers. Toxicology 1988;51:119-32.
    • (1988) Toxicology , vol.51 , pp. 119-132
    • Hannemann, J.1    Baumann, K.2
  • 6
    • 0027160113 scopus 로고
    • Beneficial effect of acetylcysteine on cisplatin nephrotoxicity in rats
    • Appenroth D, Winnefeld K, Schröter H, et al. Beneficial effect of acetylcysteine on cisplatin nephrotoxicity in rats. J Appl Toxicol 1993;13:189-92.
    • (1993) J Appl Toxicol , vol.13 , pp. 189-192
    • Appenroth, D.1    Winnefeld, K.2    Schröter, H.3
  • 7
    • 0028904311 scopus 로고
    • Functional and morphologic aspects of thallium-induced nephrotoxicity in rats
    • Appenroth D, Gambaryan S, Winnefeld K, et al. Functional and morphologic aspects of thallium-induced nephrotoxicity in rats. Toxicology 1995;96:203-15.
    • (1995) Toxicology , vol.96 , pp. 203-215
    • Appenroth, D.1    Gambaryan, S.2    Winnefeld, K.3
  • 8
    • 77957179384 scopus 로고
    • Mechanism of protection by diethyldithiocarbamate against cisplatin ototoxicity: Antioxidant system
    • Rybak LP, Ravi R, Somani SM. Mechanism of protection by diethyldithiocarbamate against cisplatin ototoxicity: antioxidant system. Fundam Appl Toxicol 1995;26:293-300.
    • (1995) Fundam Appl Toxicol , vol.26 , pp. 293-300
    • Rybak, L.P.1    Ravi, R.2    Somani, S.M.3
  • 9
    • 0029012886 scopus 로고
    • Mechanism of cisplatin ototoxicity: Antioxidant system
    • Ravi R, Somani SM, Rybak LP. Mechanism of cisplatin ototoxicity: antioxidant system. Pharmacol Toxicol 1995;76:386-94.
    • (1995) Pharmacol Toxicol , vol.76 , pp. 386-394
    • Ravi, R.1    Somani, S.M.2    Rybak, L.P.3
  • 10
    • 0020427486 scopus 로고
    • Biology of disease: Free radicals and tissue injury
    • Freeman BA, Crapo JD. Biology of disease: free radicals and tissue injury. Lab Invest 1982;47:412-26.
    • (1982) Lab Invest , vol.47 , pp. 412-426
    • Freeman, B.A.1    Crapo, J.D.2
  • 11
    • 0029834603 scopus 로고    scopus 로고
    • Immediate early gene expression in response to cerebral ischemia, friend or foe?
    • Atkins PT, Liu PK, Hsu CY. Immediate early gene expression in response to cerebral ischemia, friend or foe? Stroke 1996;27:1682-7.
    • (1996) Stroke , vol.27 , pp. 1682-1687
    • Atkins, P.T.1    Liu, P.K.2    Hsu, C.Y.3
  • 12
    • 0027946686 scopus 로고
    • Altered gene expression in neurons during programmed cell death: Identification of c-Jun as necessary for neuronal apoptosis
    • Estus S, Zaks WJ, Freeman RS, et al. Altered gene expression in neurons during programmed cell death: identification of c-Jun as necessary for neuronal apoptosis. J Cell Biol 1994;127:1717-27.
    • (1994) J Cell Biol , vol.127 , pp. 1717-1727
    • Estus, S.1    Zaks, W.J.2    Freeman, R.S.3
  • 13
    • 0029015588 scopus 로고
    • A novel protein expressed in mammalian cells undergoing apoptosis
    • Grand RJA, Milner AE, Mustor T, et al. A novel protein expressed in mammalian cells undergoing apoptosis. Exper Cell Res 1995;218:439-51.
    • (1995) Exper Cell Res , vol.218 , pp. 439-451
    • Grand, R.J.A.1    Milner, A.E.2    Mustor, T.3
  • 14
    • 0030590257 scopus 로고    scopus 로고
    • Strong c-Jun immunoreactivity is associated with apoptotic cell death in human tumors of the central nervous system
    • Ferrer I, Seguí J, Olivé M. Strong c-Jun immunoreactivity is associated with apoptotic cell death in human tumors of the central nervous system. Neurosci Lett 1996;214:49-52.
    • (1996) Neurosci Lett , vol.214 , pp. 49-52
    • Ferrer, I.1    Seguí, J.2    Olivé, M.3
  • 15
    • 0026004501 scopus 로고
    • Phosphorylation of c-jun mediated by MAP kinases
    • Pulverer BJ, Kyriakis JM, Avruch J, et al. Phosphorylation of c-jun mediated by MAP kinases. Nature 1991;353:670-4.
    • (1991) Nature , vol.353 , pp. 670-674
    • Pulverer, B.J.1    Kyriakis, J.M.2    Avruch, J.3
  • 16
    • 0026696344 scopus 로고
    • Oncoprotein-mediated signaling cascade stimulates c-Jun activity by phosphorylation of serines 63 and 73
    • Smeal T, Binetruy B, Mercola D, et al. Oncoprotein-mediated signaling cascade stimulates c-Jun activity by phosphorylation of serines 63 and 73. Mol Cell Biol 1992;12:3507-13.
    • (1992) Mol Cell Biol , vol.12 , pp. 3507-3513
    • Smeal, T.1    Binetruy, B.2    Mercola, D.3
  • 17
    • 0031972678 scopus 로고    scopus 로고
    • Phosphorylation of c-Jun is necessary for apoptosis induced by survival signal withdrawal in cerebellar granule neurons
    • Watson A, Eilers A, Lallemand D, et al. Phosphorylation of c-Jun is necessary for apoptosis induced by survival signal withdrawal in cerebellar granule neurons. J Neurosci 1998;18:751-62.
    • (1998) J Neurosci , vol.18 , pp. 751-762
    • Watson, A.1    Eilers, A.2    Lallemand, D.3
  • 18
    • 0028935974 scopus 로고
    • Independent human MAP-kinase signal transduction pathways defined by MEK and MKK isoforms
    • Derijard B, Raingeand J, Barrett T, et al. Independent human MAP-kinase signal transduction pathways defined by MEK and MKK isoforms. Science 1995;267:682-5.
    • (1995) Science , vol.267 , pp. 682-685
    • Derijard, B.1    Raingeand, J.2    Barrett, T.3
  • 19
    • 0030703604 scopus 로고    scopus 로고
    • Regulation and function of the JNK subgroup of MAP kinases
    • Minden A, Karin M. Regulation and function of the JNK subgroup of MAP kinases. Biochem Biophys Acta 1997;1333:F85-104.
    • (1997) Biochem Biophys Acta , vol.1333
    • Minden, A.1    Karin, M.2
  • 20
    • 0029744885 scopus 로고    scopus 로고
    • Sounding the alarm: Protein kinase cascades activated by stress and inflammation
    • Kyriakis JM, Avruch J. Sounding the alarm: protein kinase cascades activated by stress and inflammation. J Biol Chem 1996;271:24313-6.
    • (1996) J Biol Chem , vol.271 , pp. 24313-24316
    • Kyriakis, J.M.1    Avruch, J.2
  • 21
    • 0033523683 scopus 로고    scopus 로고
    • Chronic stimulation by a cochlear implant promotes survival of spiral ganglion neurons after neonatal deafness
    • Leake PA, Hradek GT, Snyder RL. Chronic stimulation by a cochlear implant promotes survival of spiral ganglion neurons after neonatal deafness. J Comp Neurol 1999:412:543-62.
    • (1999) J Comp Neurol , vol.412 , pp. 543-562
    • Leake, P.A.1    Hradek, G.T.2    Snyder, R.L.3
  • 22
    • 0021061824 scopus 로고
    • Histologic evaluation of temporal bones with cochlear implants
    • Linthicum FR Jr, Galey FR. Histologic evaluation of temporal bones with cochlear implants. Ann Otol Rhinol Laryngol 1983;92:610-3.
    • (1983) Ann Otol Rhinol Laryngol , vol.92 , pp. 610-613
    • Linthicum F.R., Jr.1    Galey, F.R.2
  • 23
    • 0030998626 scopus 로고    scopus 로고
    • Protection of both auditory hair cells and auditory neurons from cisplatin induced damage
    • Gabaizadeh R, Staecker H, Liu W, et al. Protection of both auditory hair cells and auditory neurons from cisplatin induced damage. Acta Otolaryngol 1997;117:232-8.
    • (1997) Acta Otolaryngol , vol.117 , pp. 232-238
    • Gabaizadeh, R.1    Staecker, H.2    Liu, W.3
  • 24
    • 0037088935 scopus 로고    scopus 로고
    • The mitochondrial toxin 3-nitropropionic acid induces striatal neurodegeneration via a c-Jun N-terminal kinase/c-Jun module
    • Garcia M, Vanhoutte P, Pages C, et al. The mitochondrial toxin 3-nitropropionic acid induces striatal neurodegeneration via a c-Jun N-terminal kinase/c-Jun module. J Neurosci 2002;22:2174-84.
    • (2002) J Neurosci , vol.22 , pp. 2174-2184
    • Garcia, M.1    Vanhoutte, P.2    Pages, C.3
  • 25
    • 0030857126 scopus 로고    scopus 로고
    • Activation of c-Jun N-terminal kinase antagonizes an anti-apoptotic action of Bcl-2
    • Park J, Kim I, Oh Y, et al. Activation of c-Jun N-terminal kinase antagonizes an anti-apoptotic action of Bcl-2. J Biol Chem 1997;272:16725-8.
    • (1997) J Biol Chem , vol.272 , pp. 16725-16728
    • Park, J.1    Kim, I.2    Oh, Y.3
  • 26
    • 0029838165 scopus 로고    scopus 로고
    • Ordering the cell death pathway
    • Park D, Stefanis L, Yun C, et al. Ordering the cell death pathway. J Biol Chem 1996;271:21898-905.
    • (1996) J Biol Chem , vol.271 , pp. 21898-21905
    • Park, D.1    Stefanis, L.2    Yun, C.3
  • 27
    • 17344374130 scopus 로고    scopus 로고
    • Motoneuron apoptosis is blocked by CEP-1347 (KT 7515), a novel inhibitor of the JNK signaling pathway
    • Maroney A, Glicksman M, Basma A, et al. Motoneuron apoptosis is blocked by CEP-1347 (KT 7515), a novel inhibitor of the JNK signaling pathway. J Neurosci 1998;18:104-11.
    • (1998) J Neurosci , vol.18 , pp. 104-111
    • Maroney, A.1    Glicksman, M.2    Basma, A.3
  • 28
    • 0033994234 scopus 로고    scopus 로고
    • Rescue of hearing, auditory hair cells, and neurons by CEP-1347/KT7515, an inhibitor of c-Jun N-terminal kinase activation
    • Pirvola U, Xing-Qun L, Virkkala J, et al. Rescue of hearing, auditory hair cells, and neurons by CEP-1347/KT7515, an inhibitor of c-Jun N-terminal kinase activation. J Neurosci 2000;20:43-50.
    • (2000) J Neurosci , vol.20 , pp. 43-50
    • Pirvola, U.1    Xing-Qun, L.2    Virkkala, J.3
  • 29
    • 0344258124 scopus 로고    scopus 로고
    • Lack of c-Jun activity increases survival to cisplatin
    • Sanchez-Perez I, Perona R. Lack of c-Jun activity increases survival to cisplatin. FEBS Lett 1999;453:151-8.
    • (1999) FEBS Lett , vol.453 , pp. 151-158
    • Sanchez-Perez, I.1    Perona, R.2
  • 30
    • 0030986669 scopus 로고    scopus 로고
    • Evidence that 4-hydroxy nonenal mediates oxidative stress-induced neuronal apoptosis
    • Kruman I, Bruce-Keller A, Bredesen D, et al. Evidence that 4-hydroxy nonenal mediates oxidative stress-induced neuronal apoptosis. J Neurosci 1997;17:5089-100.
    • (1997) J Neurosci , vol.17 , pp. 5089-5100
    • Kruman, I.1    Bruce-Keller, A.2    Bredesen, D.3
  • 31
    • 0033985185 scopus 로고    scopus 로고
    • The lipid peroxidation product 4-hydroxy-2,3-nonenal increases AP-1-binding activity through caspase activation in neurons
    • Camandola S, Poli G, Mattson M. The lipid peroxidation product 4-hydroxy-2,3-nonenal increases AP-1-binding activity through caspase activation in neurons. J Neurochem 2000;74:159-68.
    • (2000) J Neurochem , vol.74 , pp. 159-168
    • Camandola, S.1    Poli, G.2    Mattson, M.3
  • 32
    • 0033593225 scopus 로고    scopus 로고
    • Activation of stress signaling pathways by the end product of lipid peroxidation
    • Uchida K, Shiraishi M, Naito Y, et al. Activation of stress signaling pathways by the end product of lipid peroxidation. J Biol Chem 1999;274:2234-42.
    • (1999) J Biol Chem , vol.274 , pp. 2234-2242
    • Uchida, K.1    Shiraishi, M.2    Naito, Y.3
  • 33
    • 0033863837 scopus 로고    scopus 로고
    • Selective activation of the c-Jun N-terminal protein kinase pathway during 4-hydroxy nonenal-induced apoptosis of PC12 cells
    • Soh Y, Jeong KS, Lee IJ, et al. Selective activation of the c-Jun N-terminal protein kinase pathway during 4-hydroxy nonenal-induced apoptosis of PC12 cells. Mol Pharmacol 2000;58:535-41.
    • (2000) Mol Pharmacol , vol.58 , pp. 535-541
    • Soh, Y.1    Jeong, K.S.2    Lee, I.J.3
  • 34
    • 0032422051 scopus 로고    scopus 로고
    • HNE interacts directly with JNK isoforms in human hepatic stellate cells
    • Parola M, Robino G, Marra F, et al. HNE interacts directly with JNK isoforms in human hepatic stellate cells. J Clin Invest 1998;102:1942-50.
    • (1998) J Clin Invest , vol.102 , pp. 1942-1950
    • Parola, M.1    Robino, G.2    Marra, F.3
  • 35
    • 0026045073 scopus 로고
    • Suppression of c-Jun/AP-1 activation by an inhibitor of tumor promotion in mouse fibroblast cells
    • Huang T-S, Lee S-C, Lin J-K. Suppression of c-Jun/AP-1 activation by an inhibitor of tumor promotion in mouse fibroblast cells. Proc Natl Acad Sci USA 1991;88:5292-6.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 5292-5296
    • Huang, T.-S.1    Lee, S.-C.2    Lin, J.-K.3
  • 36
    • 0031394645 scopus 로고    scopus 로고
    • Suppression of protein kinase C and nuclear oncogene expression as possible molecular mechanisms of cancer chemoprevention by apigenin and curcumin
    • Lin JK, Chen YC, Huang YT, et al. Suppression of protein kinase C and nuclear oncogene expression as possible molecular mechanisms of cancer chemoprevention by apigenin and curcumin. J Cell Biochem Suppl 1997;28-29:39-48.
    • (1997) J Cell Biochem Suppl , vol.28-29 , pp. 39-48
    • Lin, J.K.1    Chen, Y.C.2    Huang, Y.T.3
  • 37
    • 0029166667 scopus 로고
    • A synthetic inhibitor of the mitogen-activated protein kinase cascade
    • Dudley DT, Pang L, Decker SJ, et al. A synthetic inhibitor of the mitogen-activated protein kinase cascade. Proc Natl Acad Sci USA 1995;92:7686-9.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 7686-7689
    • Dudley, D.T.1    Pang, L.2    Decker, S.J.3
  • 38
    • 0028884033 scopus 로고
    • PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase Kinase in vitro and in vivo
    • Alessi D, Cuenda A, Cohen P, et al. PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase Kinase in vitro and in vivo. J Biol Chem 1995;270:27489-94.
    • (1995) J Biol Chem , vol.270 , pp. 27489-27494
    • Alessi, D.1    Cuenda, A.2    Cohen, P.3
  • 39
    • 0032937879 scopus 로고    scopus 로고
    • Withdrawal of survival factors results in activation of the JNK pathway in neuronal cells leading to Fas ligand induction and cell death
    • Le-Niculescu H, Bonfoco E, Kasuya Y, et al. Withdrawal of survival factors results in activation of the JNK pathway in neuronal cells leading to Fas ligand induction and cell death. Mol Cell Biol 1999;19:751-63.
    • (1999) Mol Cell Biol , vol.19 , pp. 751-763
    • Le-Niculescu, H.1    Bonfoco, E.2    Kasuya, Y.3
  • 40
    • 0032524763 scopus 로고    scopus 로고
    • Inhibitors of p38 mitogenactivated protein kinase promote neuronal survival in vitro
    • Horstmann S, Kahle P, Borasio G. Inhibitors of p38 mitogenactivated protein kinase promote neuronal survival in vitro. J Neurosci Res 1998;52:483-90.
    • (1998) J Neurosci Res , vol.52 , pp. 483-490
    • Horstmann, S.1    Kahle, P.2    Borasio, G.3
  • 41
    • 0035869341 scopus 로고    scopus 로고
    • Evidence for redox regulation of cytochrome-C release during programmed neuronal death: Antioxidant effects of protein synthesis and caspase inhibition
    • Kirkland RA, Franklin JL. Evidence for redox regulation of cytochrome-C release during programmed neuronal death: antioxidant effects of protein synthesis and caspase inhibition. J Neurosci 2001;21:1949-63.
    • (2001) J Neurosci , vol.21 , pp. 1949-1963
    • Kirkland, R.A.1    Franklin, J.L.2
  • 42
    • 0037092420 scopus 로고    scopus 로고
    • Target depletion of distinct tumor necrosis factor receptor subtypes reveals hippocampal neuron death and survival through different signal transduction pathways
    • Yang L, Lindholm K, Konishi Y, et al. Target depletion of distinct tumor necrosis factor receptor subtypes reveals hippocampal neuron death and survival through different signal transduction pathways. J Neurosci 2002;22:3025-32.
    • (2002) J Neurosci , vol.22 , pp. 3025-3032
    • Yang, L.1    Lindholm, K.2    Konishi, Y.3
  • 43
    • 14444281569 scopus 로고    scopus 로고
    • Induction of apoptosis by ASK1 a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways
    • Ichijo H, Nishida E, Irie K, et al. Induction of apoptosis by ASK1 a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways. Science 1997;275:90-4.
    • (1997) Science , vol.275 , pp. 90-94
    • Ichijo, H.1    Nishida, E.2    Irie, K.3
  • 44
    • 0035933061 scopus 로고    scopus 로고
    • Pro-apoptotic gene expression mediated by the p38 mitogen-activated protein kinase signal transduction pathway
    • De Zutter G, Davis R. Pro-apoptotic gene expression mediated by the p38 mitogen-activated protein kinase signal transduction pathway. Proc Natl Acad Sci USA 2001;98:6168-73.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 6168-6173
    • De Zutter, G.1    Davis, R.2
  • 45
    • 0029961252 scopus 로고    scopus 로고
    • Differential activation of ERK, JNK/SAPK, and p38/CSBP/RK MAP kinase family members during the cellular response to arsenite
    • Liu Y, Guyton K, Gorospe M, et al. Differential activation of ERK, JNK/SAPK, and p38/CSBP/RK MAP kinase family members during the cellular response to arsenite. Free Radic Biol Med 1996;21:771-81.
    • (1996) Free Radic Biol Med , vol.21 , pp. 771-781
    • Liu, Y.1    Guyton, K.2    Gorospe, M.3
  • 46
    • 0036278083 scopus 로고    scopus 로고
    • Mechanisms of cell death in the injured auditory system: Otoprotective strategies
    • Lefebvre P, Malgrange B, Lallemend F, et al. Mechanisms of cell death in the injured auditory system: otoprotective strategies. Audiol Neurotol 2002;7:165-70.
    • (2002) Audiol Neurotol , vol.7 , pp. 165-170
    • Lefebvre, P.1    Malgrange, B.2    Lallemend, F.3
  • 49
    • 0023121862 scopus 로고
    • Multichannel intracochlear electrodes: Mechanism of insertion trauma
    • Kennedy DW. Multichannel intracochlear electrodes: mechanism of insertion trauma. Laryngoscope 1987;97:42-9.
    • (1987) Laryngoscope , vol.97 , pp. 42-49
    • Kennedy, D.W.1
  • 50
    • 0035990161 scopus 로고    scopus 로고
    • Modiolar proximity of three new perimodiolar cochlear implant electrodes
    • Balkany TJ, Eshraghi AA. Yang N. Modiolar proximity of three new perimodiolar cochlear implant electrodes. Acta Otolaryngol 2002;122:363-9.
    • (2002) Acta Otolaryngol , vol.122 , pp. 363-369
    • Balkany, T.J.1    Eshraghi, A.A.2    Yang, N.3
  • 52
    • 0031775797 scopus 로고    scopus 로고
    • Intracochlear factors contributing to psychophysical percepts following cochlear implantation
    • Kawano A, Seldon L, Clark GM, Ramsden RT, Raine CH. Intracochlear factors contributing to psychophysical percepts following cochlear implantation. Acta Otolaryngol 1998;118:313-26.
    • (1998) Acta Otolaryngol , vol.118 , pp. 313-326
    • Kawano, A.1    Seldon, L.2    Clark, G.M.3    Ramsden, R.T.4    Raine, C.H.5


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