Early and persistent alterations in prefrontal cortex MAO A and B in Aizheimer's disease

Journal of Neural Transmission

Volumn 110, Issue 7, 2003, Pages 789-801

  Kennedy, B P ^a   Ziegler, M G ^a   Alford, M ^b   Hansen, L A ^b,c   Thal, L J ^b   Masliah, E ^b,c  

^a UCSD MEDICAL CENTER   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Alzheimer's disease; Cognitive function; Monoamine oxidase A; Monoamine oxidase B; Prefrontal cortex

Indexed keywords

ACYLTRANSFERASE; AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME A; AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME B;

AGED; ALZHEIMER DISEASE; ARTICLE; COGNITION; CONTROLLED STUDY; ENZYME ACTIVITY; GLIA; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; NEUROFIBRILLARY TANGLE; NEUROTOXICITY; ONSET AGE; PREFRONTAL CORTEX; PRIORITY JOURNAL; RADIOENZYMATIC ASSAY; SENILE PLAQUE;

EID: 0037789491     PISSN: 03009564     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00702-003-0828-6     Document Type: Article

References (64)

1. Abi-Dargham A, Mawlawi O, Lombardo I, Gil R, Martinez D, Huang Y, Hwang DR, Keilp J, Kochan L, Van heertum R, Gorman JM. Laruelle M (2002) Prefrontal dopamine D1 receptors and working memory in schizophrenia. J Neurosci 22: 3708-3719
2. Adolfsson R, Gottfries C-G, Oreland L, Wiberg A, Winblad B (1980) Increased activity of brain and platelet monoamine oxidase in dementia of Alzheimer type. Life Sci 27: 1029-1034
3. Bal N, Figueras G, Vilaro MT, Sunol C, Artigas F (1997) Antidepressant drugs inhibit a glial 5-hydroxytryptamine transporter in rat brain. Eur J Neurosci 9: 1728-1738
4. Balciuniene J, Emilsson L, Oreland L, Petterson U, Jazin EE (2002) Investigation of the functional effect of monoamine oxidase polymorphisms in human brain. Hum Genet 110: 1-7
5. Bongioanni P, Donato M, Castagna M, Gemignani F (1996) Platelet phenolsulphotransferase activity, monoamine oxidase activity and peripheral-type benzodiazepine binding in demented patients. J Neural Transm 103: 491-501
6. Bongioanni P, Gemignani F, Boccardi B, Borgna M, Rossi B (1997) Platelet monoamine oxidase molecular activity in demented patients. Ital J Neurol Sci 18: 151-156
7. Bouras C, Giannakopoulos P, Good PF, Hsu A, Hof PR, Perl DP (1997) A laser microprobe mass analysis of brain aluminum and iron in dementia pugilistica: comparison with Alzheimer disease. Eur Neurol 38: 53-58
8. Burke WJ, Li SW, Schmitt CA, Xia P, Chung HD, Gillespie KN (1999) Accumulation of 3,4-dihyroxyphenylglycolaldehyde, the neurotoxic monoamine oxidase A metabolite of norepinephrine, in locus ceruleus cell bodies in Alzheimer's disease: mechanism of neuron death. Brain Res 816: 633-637
9. Burke WJ, Li SW, Zahm DS, Macarthur H, Kolo LL, Westfall TC, Anwar M, Glickstein SB, Ruggerio DA (2001) Catecholamine monoamine oxidase a metabolite in adrenergic neurons is cytotoxic in vivo. Brain Res 891: 218-227
10. Braak H, Braak E (1991) Neuropathological stageing of Alzheimer-related changes. Acta Neruopathol 82: 239-259
11. Carlo P, Violani E, Del Rio M, Olasmaa M, Santagati S, Maggi A, Picotti GB (1996) Monoamine oxidase B expression is selectively regulated by dexamethasone in cultured rat astrocytes. Brain Res 711: 175-183
12. Chan-Palay V, Hochli M, Savaskan E, Hungerecker G (1993) Calbindin D-28k and monoamine oxidase A immunoreactive neurons in the nucleus basalis of Meynert in senile dementia of the Alzheimer type and Parkinson's disease. Dementia 4: 1-15
13. Damaiso AR (1995) On some functions of the human prefrontal cortex. J Neurosci 21: 35-44
14. Ekblom J, Jossan SS, Bergstrom M, Oreland L, Walum E, Aquilonius SM (1993) Monoamine oxidase-B in astrocytes. Glia 8: 122-132
15. Elrod R, Peskind ER, DiGiacomo L, Brodkin KI, Veith RC, Raskind MA (1997) Effects of Alzheimer's disease severity on cerebrospinal fluid norepinephrine concentration. Am J Psychiatry 154: 25-30
16. Emilssson L, Saetre P, Balciuniene J, Castensson A, Cairns N, Jazin EE (2002) Increased monoamine oxidase messenger RNA expression levels in frontal cortex of Alzheimer's disease patients. Neurosci Lett 326: 56-60
17. Esiri MM, Pearson RC, Steele JE, Bowen DM, Powell TP (1990) A quanitative study of the neurofibrillary tangles and the choline acetyltransferase activity in the cerebral cortex and the amygdala in Alzheimer's disease. J Neurol Neurosurg Psychiatry 53: 161-165
18. Fischer P, Gotz ME, Ellinger B, Streifler M, Riederer P, Daneilczyk W (1994) Platelet monoamine oxidase B activity and vitamin B12 in dementia. Biol Psychiatry 35: 772-774
19. Fitzgerald LW, Kaplinsky L, Kimelberg HK (1990) Serotonin metabolism by monoamine oxidase in rat primary astrocyte cultures. J Neurochem 55: 2008-2014
20. Fonnum F (1969) Radiochemical microassays for the determination of choline acetyl transferase and acetyl cholinesterase activities. J Biochem 115: 465-472
21. Fowler CJ, Wiberg A, Oreland L, Marcusson J, Winblad B (1980) The effect of age on the activity and molecular properties of human brain monoamine oxidase. J Neural Transm 49: 1-20
22. Giubilei F, Patacchioli FR, Antonini G, Sepe Monti M, Tisei P, Bastianello S, Monnazzi P, Angelucci L (2001) Altered circadian cortisol secretion in Alzheimer's disease:clinical and neuroradiological aspects. J Neurosci Res 66: 262-265
23. Gottfries CG, Oreland L, Winberg A, Winblad B (1975) Lowered monoamine oxidase activity in brains from alcoholic suicides. J Neurochem 25: 667-673
24. Gotz ME, Fischer P, Gsell W, Riederer P, Streifler M, Simanyi M, Muller F, Danielczyk W (1998) Platelet monoamine oxidase B activity in dementia. A 4-year follow-up. Dement Geriatr Cogn Disord 9: 74-77
25. Hansen L, Masliah E, Quijada-Fawcett S, Rexin D (1991) Entorhinal neurofibrillary tangles in Alzheimer disease with Lewy bodies. Neurosci Lett 129: 269-272
26. Hansen L, De Teresa R, Davies P, Terry R (1998) Neocortical morphometry, lesion counts, and choline acetyltransferase levels in the age spectrum of Alzheimer's disease. Neurology 38: 48-54
27. Jossan SS, Gillberg PG, Gottfries CG, Karlsson I, Oreland L (1991) Monoamine oxidase B in brains from patients with Alzheimer's disease: a biochemical and autoradiographical study. Neurosci 45: 1-12
28. Kalaria RN, Andorn AC, Tabaton M, Whitehouse PJ, Harik SI, Unnerstall JR (1989) Adrenergic receptors in aging and Alzheimer's disease: increased beta 2-receptors in prefrontal cortex and hippocampus. J Neurochem 53: 1772-1781
29. Kumlein E, Sherif F, Ge L, Oreland L (1995) Platelet and brain GABA-transaminase and monoamine oxidase activities in patients with complex partial seizures. Epilepsy Res 20: 161-170
30. Lewinsohn R, Bohm K-H, Glover V, Sandler M (1978) A benzylamine oxidase distinct from monoamine oxidase B-widespread distribution in man and rat. Biochem Pharmacol 27: 1857-1863
31. Lovell MA, Ehmann WD, Markesbery WR (1993) Laser microprobe analysis of brain aluminum in Alzheimer's disease. Ann Neurol 33: 36-42
32. Masliah E, Miller A, Terry RD (1993) The synaptic organization of the neocortex in Alzheimer's disease. Med Hypotheses 41: 334-340
33. Minger SL, Honer WG, Esiri MM, McDonald B, Keene J, Nicoll JA, Carter J, Hope T, Francis PT (2001) Synaptic pathology in prefrontal cortex is present only with severe dementia in Alzheimer disease. J Neuropathol Exp Neurol 60: 929-936
34. Mirra S, Gearing M, Mc Keel DJ, Crain B, Hughes J, Van Belle G, Heyman A (1994) Interlaboratory comparison of neuropathology assessments in Alzheimer's disease. A study of the consortium to establish a registry for Alzheimer's disease (CERAD). J Neuropathol Exp Neurol 53: 303-315
35. Murphy BL, Arnsten AFT, Goldman-Rakic PS, Roth RH (1996) Increased dopamine turnover in the prefrontal cortex impairs spatial working memory performance in rats and monkeys. Proc Natl Acad Sci USA 93: 1325-1329
36. Nakamura S, Kawamata T, Akiguchi I, Kameyama M, Nakamyura N, Kimera H (1990) Expression of monoamine oxidase B activity in astrocytes of senile plaques. Acta Neuropathol (Berl) 80: 419-425
37. Oreland L, Fowler CJ, Carlsson A, Magnusson T (1980) Monoamine oxidase -A and -B activity in the rat brains after hemitransection. Life Sci 26: 139-146
38. Owesson CA, Hopwood SE, Callado LF, Seif I, McLaughlin DP, Stamford JA (2002) Altered presynaptic function in monoaminergic neurons of monoamine oxidase-A knockout mice. Eur J Neurosci 15: 1516-1522
39. Palmer AM (1996) Neurochemical studies in Alzheimer's disease. Neurodegeneration 5: 381-391
40. Pappas BA, Bayley PJ, Bui BK, Hansen LA, Thal LJ (2000) Choline acetyltransferase activity and cognitive domain scores of Alzheimer's patients. Neurobiol Aging 21: 11-17
41. Parnetti L, Reboldi GP, Santucci C, Santucci A, Gaiti A, Brunetti M, Cecchetti R, Senin U (1994) Platelet MAO-B activity as a marker of behavioural characteristics in dementia disorders. Aging Clin Exp Res 6: 201-207
42. Pedersen NL, Oreland L, Reynolds C, McClearn GE (1993) Importance of genetic effects for monoamine oxidase activity in thrombocytes in twins reared apart and twins reared together. Psychiatry Res 46: 239-251
43. Peskind ER, Wingerson D, Murray S, Pascualy M, Dobie DJ, Le Corre P, Le Verge R, Veith RC, Raskind MA (1995) Effects of Alzheimer's disease and normal aging on cerebrospinal fluid norepinephrine responses to yohimbine and clonidine. Arch Gen Psychiatry 52: 774-782
44. Priest RG, Gimbrett R, Roberts M, Steinert J (1995) Reversible and selective inhibitors of monoamine oxidase A in mental and other disorders. Acta Psychiatr Scand [Suppl] 386: 40-43
45. Raskind MA, Peskind ER, Halter JB, Jimerson DC (1984) Norepinephrine and MHPG levels in CSF and plasma in Alzheimer's disease. Arch Gen Psychiatry 41: 343-346
46. Rasmuson S, Andrew R, Nasman B, Seckl JR, Walker BR, Olsson T (2001) Increased glucocorticoid production and altered cortisol metabolism in women with mild to moderate Alzheimer's disease. Biol Psychiatry 49: 547-552
47. Reinikainen KJ, Paljarvi L, Halonen T, Malminen O, Kosma VM, Laaksos M, Riekkinen PJ (1988) Dopaminergic system and monoamine oxidase-B activity in Alzheimer's disease. Neurobiol Aging 9: 245-252
48. Robinson DS, Davis JM, Nies A, Ravaris CL, Sylvester D (1971) Relation of sex and aging to monoamine oxidase activity of human brain, plasma, and platelets. Arch Gen Psychiatry 24: 536-539
49. Saura J, Bleulel Z, Ulrich J, Mendelowitsch A, Chen K, Shih C, Malherbe P, Da Prada M, Richards JG (1996) Molecular neuroanatomy of human monoamine oxidases A and B revealed by quantitative enzyme radioautography and in situ hybridization histochemistry. Neuroscience 70: 755-774
50. Sherif F, Gottfries CG, Alafuzoff I, Oreland L (1992) Brain gamma-aminobutyrate aminotransferase (GABA-T) and monoamine oxidase (MAO) in patients with Alzheimer's disease. J Neural Transm [P-D Sect] 4: 227-240
51. Shih JC, Grimsby J, Chen K, Zhu QS (1993) Structure and promoter organization of the human monoamine oxidase A and B genes. J Psychiatry Neurosci 18: 25-32
52. Slotkin TA, Seidler FJ, Ritchie (1998) Effects of aging and glucocorticoid treatment on monoamine oxidase subtypes in rat cerebral cortex: therapeutic implications. Brain Res Bull 47: 345-348
53. Soinen H, Reinikainen KJ, Partanen J, Helkala EL, Paljarvi L, Riekkinin PJ (1992) Slowing of the electroencephalogram and choline acetyltransferase activity in post mortem frontal cortex in definite Alzheimer's disease. Neurosci 49: 529-535
54. Song W, Zhou LJ, Zheng SX, Zhu XZ (2000) Amyloid-beta 25-35 peptide induces expression of monoamine oxidase B in cultured rat astrocytes. Acta Pharmacol Sin 21: 557-563
55. Soto J, Ulibarri I, Jauregui JV, Ballesteros J, Meana JJ (1999) Dissociation between 12-imidazoline receptors and MAO-B activity in platelets of patients with Alzheimer's type dementia. J Psychiatr Res 33: 251-257
56. Takehashi M, Tanaka S, Masliah E, Ueda K (2002) Association of monoamine oxidase A gene polymorphism with Alzheimer's disease and Lewy body variant. Neurosci Lett 327: 79-82
57. Talbot K, Young RA, Jolly-Tornetta C, Lee VM, Trojanowski JQ, Wolf BA (2000) A frontal variant of Alzheimer's disease exhibits decreased calcium-independent phospholipase A2 activity in the prefrontal cortex. Neurochem Int 37: 17-31
58. Tariot PN, Sunderland T, Weingartner H, Murphy DL, Welkowitz JA, Thompson K, Cohen RM (1987) Cognitive effects of L-deprenyl in Alzheimer's disease. Psychopharmacology (Berl) 91: 489-495
59. Weinberger DR, Egan MF, Bertolino A, Callicott JH, Mattay VS, Lipska BK, Berman KF, Goldberg TE (2001) Prefrontal neurons and the genetics of schizophrenia. Biol Psychiatry 50: 825-844
60. Westlund KN, Denney RM, Rose RM, Abell CW (1988) Localization of distinct monoamine oxidase A and monoamine oxidase B cell populations in human brainstem. Neurosci 26: 791-802
61. Williams GV, Goldman-Rakic PS (1995) Modulation of memory fields by dopamine D1 receptors in the prefrontal cortex. Nature 376: 572-575
62. Winblad B, Gottfries CG, Oreland L, Wiberg A (1979) Monoamine oxidase in platelets and brains of non-psychiatric and non-neurological geriatric patients. Med Biol 57: 129-132
63. Young WF Jr, Laws ER Jr, Sharbrough FW, Weinshilboum RM (1986) Human monoamine oxidase. Lack of brain and platelet correlation. Arch Gen Psychiatry 43: 604-609
64. Zatta P, Zambenedetti P, Milanese M (1999) Activation of monoamine oxidase type-B by aluminum in rat brain homogenate. Neuroreport 10: 3645-3648