Dissociation between I2-imidazoline receptors and MAO-B activity in platelets of patients with Alzheimer's type dementia

Journal of Psychiatric Research

Volumn 33, Issue 3, 1999, Pages 251-257

  Soto, J ^a   Ulibarri, I ^a   Jauregui, J V ^b   Ballesteros, J ^a,b   Meana, J J ^a  

^a UNIVERSITY OF THE BASQUE COUNTRY UPV EHU   (Spain)

^b AITA   (Spain)

Author keywords

Alzheimer's disease; Dementia; I2 imidazoline receptors; Monoamine oxidase B; Neuroreceptors; Platelet

Indexed keywords

AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME B; CARBON 14; EFAROXAN; IDAZOXAN; IMIDAZOLINE I2 RECEPTOR; TRITIUM; ALPHA 2 ADRENERGIC RECEPTOR; ALPHA ADRENERGIC RECEPTOR BLOCKING AGENT; AMINE OXIDASE (FLAVIN CONTAINING); BENZOFURAN DERIVATIVE; DRUG RECEPTOR; IMIDAZOLE DERIVATIVE; IMIDAZOLINE RECEPTORS;

ADULT; AGED; ALZHEIMER DISEASE; ARTICLE; BINDING AFFINITY; BINDING SITE; BRAIN; CLINICAL ARTICLE; COGNITION; CONTROLLED STUDY; DISSOCIATION; DISSOCIATION CONSTANT; ENZYME ACTIVITY; FEMALE; HUMAN; HUMAN CELL; MALE; MITOCHONDRIAL MEMBRANE; OXIDATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; RECEPTOR DENSITY; THROMBOCYTE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; METABOLISM; MIDDLE AGED; STATISTICAL MODEL;

ADRENERGIC ALPHA-ANTAGONISTS; AGED; ALZHEIMER DISEASE; BENZOFURANS; BINDING SITES; BLOOD PLATELETS; FEMALE; HUMANS; IDAZOXAN; IMIDAZOLES; LINEAR MODELS; MALE; MIDDLE AGED; MONOAMINE OXIDASE; RECEPTORS, ADRENERGIC, ALPHA-2; RECEPTORS, DRUG;

EID: 0032587912     PISSN: 00223956     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-3956(98)00065-X     Document Type: Article

References (42)

1. Adolfsson R, Gottfries CG, Oreland L, Wiberg A, Winblad B. Increased activity of brain and platelet monoamine oxidase in dementia of Alzheimer type. Life Sciences 1980;27:1029-1034.
2. Bongioanni P, Donato M, Castagna M, Gemignani F. Platelet phenolsulphotransferase activity, monoamine oxidase activity and peripheral-type benzodiazepine binding in demented patients. Journal of Neural Transmission 1996a;103:491-501.
3. Bongioanni P, Mondino C, Boccardi B, Borgna M, Castagna M. Monoamine oxidase molecular activity in platelets of Parkinsonian and demented patients. Neurodegeneration 1996b;5:351-357.
4. 3H]idazoxan in the human cerebral cortex. Neurochemistry International 1993;22:153-163.
5. 2 sites. Journal of Pharmacology and Experimental Therapeutics 1995;272:681-688.
6. Chen K, Wu H-F, Shih JC. The deduced amino acid sequences of human platelet and frontal cortex monoamine oxidase B are identical. Journal of Neurochemistry 1993;61:187-190.
7. Da Prada M, Cesura AM, Launay JM, Richards JG. Platelets as a model for neurones?. Experientia 1988;44:115-126.
8. Delacourte A. General and dramatic glial reaction in Alzheimer brains. Neurology 1990;40:33-37.
9. Diorio D, Welner SA, Butterworth RF, Meaney MJ, Suranyi-Cadotte BE. Peripheral benzodiazepine binding sites in Alzheimer's disease frontal and temporal cortex. Neurobiology of Aging 1991;12:255-258.
10. Duffy PE, Rapport M, Graf L. Glial fibrillary acidic protein and Alzheimer type dementia. Neurology 1980;30:778-782.
11. Ekblom J, Jossan SS, Bergström M, Oreland L, Walum E, Aquilonius S-M. Monoamine oxidase-B in astrocytes. Glia 1993;8:122-132.
12. Folstein MF, Folstein SE, McHugh PR. 'Mini-Mental State': a practical method for grading the cognitive state of patients for the clinician. Journal of Psychiatric Research 1975;12:189-198.
13. Fowler CJ, Tipton KF. Concentration dependence of the oxidation of tyramine by the two forms of rat liver mitochondrial monoamine oxidase. Biochemical Pharmacology 1981;30:3329-3332.
14. García-Sevilla JA, Escribá PV, Sastre M, Walzer C, Busquets X, Jaquet G, Reis DJ, Guimón J. Immunodetection and quantitation of imidazoline receptor proteins in platelets of patients with major depression and in brains of suicide victims. Archives of General Psychiatry 1996;53:803-810.
15. García-Sevilla JA, Escribá PV, Walzer C, Bouras C, Guimón J. Imidazoline receptor proteins in brains of patients with Alzheimer's disease. Neuroscience Letters 1998;247:95-98.
16. Gómez N, Balsa D, Unzeta M. A comparative study of some kinetic and molecular properties of microsomal and mitochondrial monoamine oxidase. Biochemical Pharmacology 1988;37:3407-3413.
17. Jossan SS, Gillberg PG, Gottfries CG, Karlsson I, Oreland L. Monoamine oxidase B in brains from patients with Alzheimer's disease: a biochemical and autoradiographical study. Neuroscience 1991;45:1-12.
18. Lobo A, Saz P, Marcos G, Dia JL, De la Cámara C. The prevalence of dementia and depression in the elderly community in a Southern European population. Archives of General Psychiatry 1995;52:497-506.
19. 2-imidazoline receptors in human glioblastomas. NeuroReport 1996;7:1393-1396.
20. McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadian EM. Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's disease. Neurology 1984;34:939-944.
21. 2-adrenergic drugs also bind with high affinity to a nonadrenergic site. Molecular Pharmacology 1989;35:324-330.
22. 3H]RX821002 (2-methoxy idazoxan). Journal of Pharmacology and Experimental Therapeutics 1993;264:172-182.
23. 1-imidazoline sites in bovine adrenal medullary membranes. Naunyn Schmiedeberg's Archives of Pharmacology 1993;348:70-76.
24. Molderings GJ. Imidazoline receptors: basic knowledge, recent advances and future prospects for therapy and diagnosis. Drugs of the Future 1997;22:757-772.
25. Olmos G, Alemany R, Escribá PV, García-Sevilla JA. The effects of chronic imidazoline drug treatment on glial fibrillary acidic protein concentrations in rat brain. British Journal of Pharmacology 1994;111:997-1002.
26. 2-imidazoline receptors in rat liver. British Journal of Pharmacology 1997;121:901-912.
27. Parini A, Moudanos CG, Pizzinat N, Lanier SM. The elusive family of imidazoline binding sites. Trends in Pharmacological Sciences 1996;17:13-16.
28. Parnetti L, Reboldi GP, Santucci C, Santucci A, Gaiti A, Brunetti M, Cecchetti R, Senin U. Platelet MAO-B activity as a marker of behavioural characteristics in dementia disorders. Aging Clinical and Experimental Research 1994;6:201-207.
29. Piletz JE, Sletten K. Nonadrenergic imidazoline binding sites on human platelets. Journal of Pharmacology and Experimental Therapeutics 1993;267:1493-1502.
30. 1-imidazoline binding sites and the high affinity state of alpha-2 adrenoceptor subtypes. Journal of Pharmacology and Experimental Therapeutics 1996;279:694-702.
31. Raddatz R, Parini A, Lanier SM. Imidazoline/guanidinium binding domains on monoamine oxidases: relationship to subtypes of imidazoline-binding proteins and tissue-specific interaction of imidazoline ligands with monoamine oxidase B. Journal of Biological Chemistry 1995;270:27961-27968.
32. Raddatz R, Parini A, Lanier SM. Localization of the imidazoline binding domain on monoamine oxidase B. Molecular Pharmacology 1997;52:549-553.
33. Regunathan S, Feinstein DL, Reis DJ. Expression of nonadrenergic imidazoline sites in rat cerebral cortical astrocytes. Journal of Neuroscience Research 1993;34:681-688.
34. Reis DJ, Bousquet P, Parini A. The imidazoline receptor: pharmacology, functions, ligands and relevance to biology and medicine. Annals of New York Academy of Sciences 1995;763:1-707.
35. 2-imidazoline sites) are increased in postmortem brain from patients with Alzheimer's disease. Neuroscience Letters 1993;160:109-112.
36. 2 with monoamine oxidase-B sites. Journal of Neurochemistry 1993;61:881-889.
37. Saura J, Luque JM, Cesura AM, Da Prada M, Chan-Palay V, Huber G, Loeffler J, Richards JG. Increased monoamine oxidase B activity in plaque associated astrocytes of Alzheimer brains revealed by quantitative enzyme radioautography. Neuroscience 1994;62:15-30.
38. Schechter R, Yen S-HC, Terry RD. Fibrous astrocytes in senile dementia of the Alzheimer type. Journal of Neuropathology and Experimental Neurology 1981;40:95-101.
39. Sherif F, Gottfries CG, Alafuzoff I, Oreland L. Brain gamma-aminobutyrate aminotransferase (GABA-T) and monoamine oxidase (MAO) in patients with Alzheimer's disease. Journal of Neural Transmission (Parkinson's Disease Section) 1992;4:227-240.
40. Sparks DL, Woeltz VM, Markesbery WR. Alterations in brain monoamine oxidase activity in aging, Alzheimer's disease and Pick's disease. Archives of Neurology 1991;48:718-721.
41. Tabakoff B, Hoffman PL, Lee JM, Saito T, Willard B, De Leon-Jones F. Differences in platelet enzyme activity between alcoholics and nonalcoholics. New England Journal of Medicine 1988;318:134-139.
42. 2-imidazoline binding sites on monoamine oxidases. Journal of Biological Chemistry 1995;270:9856-9861.