Investigation of the functional effect of monoamine oxidase polymorphisms in human brain

Human Genetics

Volumn 110, Issue 1, 2002, Pages 1-7

  Emilsson, L ^a   Pettersson, U ^a   Jazin, Elena E ^a   Oreland, L ^b   Balciuniene, J ^a,c  

^a UPPSALA UNIVERSITY   (Sweden)

^b UPPSALA UNIVERSITY   (Sweden)

^c UNIVERSITY OF MINNESOTA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME A; AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME B; DNA; MESSENGER RNA; NUCLEOTIDE;

ALLELE; ARTICLE; AUTOPSY; BEHAVIOR; BRAIN; BRAIN CORTEX; CLINICAL ARTICLE; CONTROLLED STUDY; DNA EXTRACTION; ENZYME ACTIVITY; ENZYME POLYMORPHISM; EXON; GENE; GENE LINKAGE DISEQUILIBRIUM; GENOTYPE; HAPLOTYPE; HUMAN; HUMAN TISSUE; INTRON; MALE; MENTAL DISEASE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SINGLE NUCLEOTIDE POLYMORPHISM; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE;

AUTOPSY; BRAIN; CEREBRAL CORTEX; EXONS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; INTRONS; ISOENZYMES; MINISATELLITE REPEATS; MONOAMINE OXIDASE; POLYMORPHISM, SINGLE NUCLEOTIDE; PROMOTER REGIONS (GENETICS); RNA, MESSENGER; VARIATION (GENETICS);

EID: 0036461061     PISSN: 03406717     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00439-001-0652-8     Document Type: Article

References (48)

1. Balciuniene J, Syvanen AC, McLeod HL, Petterson U, Jazin EE (2001) The geographic distribution of monoamine oxidase haplotypes supports a bottleneck during the dispersion of modern humans from Africa. J Mol Evol 52:157-163
2. Brunner HG, Nelen M, Breakefield XO, Ropers HH, Oost BA van (1993) Abnormal behavior associated with a point mutation in the structural gene for monoamine oxidase A. Science 262:578-580
3. Cases O, Seif I, Grimsby J, Casper P, Chen K, Pournin S, Muller, U, Aguet M, Babinet C, Shih JC, et al. (1995) Aggressive behavior and altered amounts of brain serotonin and norepinephrine in mice lacking MAOA. Science 268:1763-1766
4. Castensson A, Emilsson L, Preece P, Jazin EE (2000) High-resolution quantification of specific mRNA levels in human brain autopsies and biopsies. Genome Res 10:1219-1229
5. Castro Costa MR, Edelstein SB, Castiglione CM, Chao H, Breakefield XO (1980) Properties of monoamine oxidase in control and Lesch-Nyhan fibroblasts. Biochem Genet 18:577-590
6. Costa P, Checkoway J, Levy D, Smith-Weller T, Franklin GM, Swanson PD, Costa LG (1997) Association of a polymorphism in intron 13 of the monoamine oxidase B gene with Parkinson disease. Am J Med Genet 74:154-156
7. Craddock N, Daniels J, Roberts E, Rees M, McGuffin P, Owen MJ (1995) No evidence for allelic association between bipolar disorder and monoamine oxidase A gene polymorphisms. Am J Med Genet 60:322-324
8. Daffner KR, Mesulam MM, Holcomb PJ, Calvo V, Acar D, Chabrerie A, Kikinis R, Jolesz FA, Rentz DM, Scinto LF (2000) Disruption of attention to novel events after frontal lobe injury in humans. J Neurol Neurosurg Psychiatry 68:18-24
9. Deckert J, Catalano M, Syagailo YV, Bosi M, Okladnova O, Di Bella D,D Nothen MM, Maffei P, Franke P, Fritze J, Maier W, Propping P, Beckmann H, Bellodi L, Lesch KP (1999) Excess of high activity monoamine oxidase A gene promoter alleles in female patients with panic disorder. Hum Mol Genet 8:621-624
10. Denney RM, Koch H, Craig IW (1999) Association between monoamine oxidase A activity in human male skin fibroblasts and genotype of the MAOA promoter-associated variable number tandem repeat. Hum Genet 105:542-551
11. Dunnen JT den, Antonarakis SE (2001) Nomenclature for the description of human sequence variations. Hum Genet 109:121-124
12. Ekblom J, Garpenstrand H, Damberg M, Chen K, Shih JC, Oreland L (1998) Transcription factor binding to the core promoter of the human monoamine oxidase B gene in the cerebral cortex and in blood cells. Neurosci Lett 258:101-104
13. Furlong RA, Ho L, Rubinsztein JS, Walsh C, Paykel ES, Rubinsztein DC (1999) Analysis of the monoamine oxidase A (MAOA) gene in bipolar affective disorder by association studies, meta-analyses, and sequencing of the promoter. Am J Med Genet 88:398-406
14. Fuster JM (1999) Synopsis of function and dysfunction of the frontal lobe. Acta Psychiatr Scand Suppl 395:51-57
15. Garpenstrand H, Ekblom J, Forslund K, Rylander G, Oreland L (2000) Platelet monoamine oxidase activity is related to MAOB intron 13 genotype. J Neural Transm 107:523-530
16. Gibson UE, Heid CA, Williams PM (1996) A novel method for real time quantitative RT-PCR. Genome Res 6:995-1001
17. Girmen AS, Baenziger J, Hotamisligil GS, Konradi C, Shalish C, Sullivan JL, Breakefield XO (1992) Relationship between platelet monoamine oxidase B activity and alleles at the MAOB locus. J Neurochem 59:2063-2066
18. Grimsby J, Lan NC, Neve R, Chen K, Shih JC (1990) Tissue distribution of human monoamine oxidase A and B mRNA. J Neurochem 55:1166-1169
19. Hallman J, Oreland L, Edman G, Schalling D (1987) Thrombocyte monoamine oxidase activity and personality traits in women with severe premenstrual syndrome. Acta Psychiatr Scand 76:225-234
20. Hamilton SP, Slager SL, Heiman GA, Haghighi F, Klein DF, Hodge SE, Weissman MM, Fyer AJ, Knowles JA (2000) No genetic linkage or association between a functional promoter polymorphism in the monoamine oxidase-A gene and panic disorder. Mol Psychiatry 5:465
21. Hinds HL, Hendriks RW, Craig IW, Chen ZY (1992) Characterization of a highly polymorphic region near the first exon of the human MAOA gene containing a GT dinucleotide and a novel VNTR motif. Genomics 13:896-897
22. Hotamisligil GS, Breakefield XO (1991) Human monoamine oxidase A gene determines levels of enzyme activity. Am J Hum Genet 49:383-392
23. Hsu YP, Schuback DE, Tivol EA, Shalish C, Murphy DL, Breakefield XO (1995) Analysis of MAOA mutations in humans. Prog Brain Res 106:67-75
24. Jahng JW, Houpt TA, Wessel TC, Chen K, Shih JC, Joh TH (1997) Localization of monoamine oxidase A and B mRNA in the rat brain by in situ hybridization. Synapse 25:30-36
25. Kornhuber J, Konradi C, Mack-Burkhardt F, Riederer P, Heinsen H, Beckmann H (1989) Ontogenesis of monoamine oxidase-A and -B in the human brain frontal cortex. Brain Res 499:81-86
26. Kurth JH, Kurth MC, Poduslo SE, Schwankhaus JD (1993) Association of a monoamine oxidase B allele with Parkinson's disease. Ann Neurol 33:368-372
27. Lim LC, Powell JF, Murray R, Gill M (1994) Monoamine oxidase A gene and bipolar affective disorder. Am J Hum Genet 54:1122-1124
28. Livingston MG, Livingston HM (1996) Monoamine oxidase inhibitors. An update on drug interactions. Drug Saf 14:219-227
29. Mellick GD, Buchanan DD, McCann SJ, James KM, Johnson AG, Davis DR, Liyou N, Chan D, Le Couteur DG (1999) Variations in the monoamine oxidase B (MAOB) gene are associated with Parkinson's disease. Mov Disord 14:219-224
30. Mesulam MM (1986) Frontal cortex and behavior. Ann Neurol 19:320-325
31. Murphy DL, Wright C, Buchsbaum M, Nichols A, Costa Jl, Wyatt RJ (1976) Platelet and plasma amine oxidase activity in 680 normals: Sex and age differences and stability over time. Biochem Med 16:254-265
32. Pedersen NL, Oreland L, Reynolds C, McClearn GE (1993) Importance of genetic effects for monoamine oxidase activity in thrombocytes in twins reared apart and twins reared together. Psychiatry Res 46:239-251
33. Petrides M (1994) Frontal lobes and behaviour. Curr Opin Neurobiol 4:207-211
34. Rice J, McGuffin P, Goldin LR, Shaskan EG, Gershon ES (1984) Platelet monoamine oxidase (MAO) activity: Evidence for a single major locus. Am J Hum Genet 36:36-43
35. Sabol SZ, Hu S, Hamer D (1998) A functional polymorphism in the monoamine oxidase A gene promoter. Hum Genet 103:273-279
36. Samochowiec J, Lesch KP, Rottmann M, Smolka M, Syagailo YV, Okladnova O, Rommelspacher H, Winterer G, Schmidt LG, Sander T (1999) Association of a regulatory polymorphism in the promoter region of the monoamine oxidase A gene with antisocial alcoholism. Psychiatry Res 86:67-72
37. Saura J, Bleuel Z, Ulrich J, Mendelowitsch A, Chen K, Shih JC, Malherbe P, Da Prada M, Richards JG (1996) Molecular neuroanatomy of human monoamine oxidases A and B revealed by quantitative enzyme radioautography and in situ hybridization histochemistry. Neuroscience 70:755-774
38. Schuback DE, Mulligan EL, Sims KB, Tivol EA, Greenberg BD, Chang SF, Yang SL, Mau YC, Shen CY, Ho MS, Yang NH, Butler MG, Fink S, Schwartz CE, Berlin F, Breakefield XO, Murphy DL, Hsu YP (1999) Screen for MAOA mutations in target human groups. Am J Med Genet 88:25-28
39. Shih JC, Thompson RF (1999) Monoamine oxidase in neuropsychiatry and behavior. Am J Hum Genet 65:593-598
40. Sobell JL, Lind TJ, Hebrink DD, Heston LL, Sommer SS (1997) Screening the monoamine oxidase B gene in 100 male patients with schizophrenia: A cluster of polymorphisms in African-Americans but lack of functionally significant sequence changes. Am J Med Genet 74:44-49
41. Stern G (1998) Neuroprotection by selegiline and other MAO inhibitors. J Neural Transm Suppl 52:99-107
42. Syvanen AC, Sajantila A, Lukka M (1993) Identification of individuals by analysis of biallelic DNA markers, using PCR and solid-phase minisequencing. Am J Hum Genet 52:46-59
43. Thomas T (2000) Monoamine oxidase-B inhibitors in the treatment of Alzheimer's disease. Neurobiol Aging 21:343-348
44. Tivol EA, Shalish C, Schuback DE, Hsu YP, Breakefield XO (1996) Mutational analysis of the human MAOA gene. Am J Med Genet 67:92-97
45. Vanyukov MM, Moss HB, Yu LM, Tarter RE, Deka R (1995) Preliminary evidence for an association of a dinucleotide repeat polymorphism at the MAOA gene with early onset alcoholism/substance abuse. Am J Med Genet 60:122-126
46. Winblad B, Gottfries CG, Oreland L, Wiberg A (1979) Monoamine oxidase in platelets and brains of non-psychiatric and non-neurological geriatric patients. Med Biol 57:129-132
47. Young WF Jr, Laws ER Jr, Sharbrough FW, Weinshilboum RM (1986) Human monoamine oxidase. Lack of brain and platelet correlation. Arch Gen Psychiatry 43:604-609
48. Zalla T, Plassiart C, Pillon B, Grafman J, Sirigu A (2001) Action planning in a virtual contex after prefrontal cortex damage. Neuropsychologia 39:759-770