Staphylococcal enterotoxin B induces anergy to conventional peptide in memory T cells

Cellular Immunology

Volumn 222, Issue 2, 2003, Pages 144-155

  Watson, Andrew R O ^a   Mittler, James N ^a   Lee, William T ^a,b  

^a STATE UNIVERSITY OF NEW YORK   (United States)

^b WADSWORTH CENTER   (United States)

Author keywords

Clonal anergy; Immune tolerance; Immunological memory; Signal transduction; T lymphocytes

Indexed keywords

ANTIGEN; FLUORESCENT DYE; MONOCLONAL ANTIBODY; OVALBUMIN; OVALBUMIN[323-339]; PBS ANTIGEN; PEPTIDE; STAPHYLOCOCCUS ENTEROTOXIN B; SUPERANTIGEN; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL ACTIVATION; CELL ASSAY; CELL CULTURE; CELL LABELING; CELL PROLIFERATION; CELL STIMULATION; CELL TYPE; CLONAL ANERGY; FEMALE; IMMUNE RESPONSE; IMMUNIZATION; IMMUNOMODULATION; IN VIVO STUDY; MALE; MEMORY CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN INTERACTION; SIGNAL TRANSDUCTION; SOLUBILITY; STAPHYLOCOCCUS; SURVIVAL; T LYMPHOCYTE; TOXIN ANALYSIS;

MURINAE;

EID: 0037783953     PISSN: 00088749     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0008-8749(03)00117-5     Document Type: Article

References (43)

1. Vitetta E.S., Berton M.T., Burger C., Kepron M., Lee W.T., Yin X.M. Memory T and B cells. Annu. Rev. Immunol. 9:1991;193-217.
2. Dutton R.W., Bradley L.M., Swain S.L. T cell memory. Annu. Rev. Immunol. 16:1998;201-223.
3. Swain S.L. Helper T cell differentiation. Curr. Opin. Immunol. 11:1999;180-185.
4. Croft M., Dubey C. Accessory molecule and costimulation requirements for CD4 T cell response. Crit. Rev. Immunol. 17:1997;89-118.
5. Janeway C.A. Jr., Yagi J., Conrad P.J., Katz M.E., Jones B., Vroegop S., Buxser S. T-cell responses to M1s and to bacterial proteins that mimic its behavior. Immunol. Rev. 107:1989;61-88.
6. Herman A., Kappler J.W., Marrack P., Pullen A.M. Superantigens: mechanism of T-cell stimulation and role in immune responses. Annu. Rev. Immunol. 9:1991;745-772.
7. Fraser J., Arcus V., Kong P., Baker E., Proft T. Superantigens - powerful modifiers of the immune system. Mol. Med. Today. 6:2000;125-132.
8. Marrack P., Kappler J. The staphylococcal enterotoxins and their relatives. Science. 248:1990;705-711.
9. Woodland D.L., Happ M.P., Gollob K.J., Palmer E. An endogenous retrovirus mediating deletion of alpha beta T cells? Nature. 349:1991;529-530.
10. + T cells in staphylococcus enterotoxin B-primed mice. J. Exp. Med. 172:1990;1065-1070.
11. Lee W.T., Vitetta E.S. Memory T cells are anergic to the superantigen, staphylocoocal enterotoxin B. J. Exp. Med. 176:1992;575-580.
12. + T-cells differing in CD45r expression. J. Immunol. 149:1992;2300-2306.
13. Farber D.L., Acuto O., Bottomly K. Differential T cell receptor-mediated signaling in naive and memory CD4 T cells. Eur. J. Immunol. 27:1997;2094-2101.
14. lo thymocytes in vivo. Science. 250:1990;1720-1722.
15. Haskins K., Kubo R., White J., Pigeon M., Kappler J., Marrack P. The major histocompatibility complex-restricted antigen receptor on T cells. I. Isolation with a monoclonal antibody. J. Exp. Med. 157:1983;1149-1169.
16. Portoles P., Rojo J., Golby A., Bonneville M., Gromkowski S., Greenbaum L., Janeway C.A. Jr., Murphy D.B., Bottomly K. Monoclonal antibodies to murine CD3 epsilon define distinct epitopes, one of which may interact with CD4 during T cell activation. J. Immunol. 142:1989;4169-4175.
17. Birkeland M.L., Metlay J., Sanders V.M., Fernandez-Botran R., Vitetta E.S., Steinman R.M., Pure E. Epitopes on CD45R (T200) molecules define differentiation antigens on murine B and T lymphocytes. J. Mol. Cell. Immunol. 4:1988;71-85.
18. Staerz U.D., Rammensee H.G., Benedetto J.D., Bevan M.J. Characterization of a murine monoclonal antibody specific for an allotypic determinant on T cell antigen receptor. J. Immunol. 134:1985;3994-4000.
19. + T cells. J. Immunol. 144:1990;3288-3295.
20. Lee W.T., Cole-Calkins J., Street N.E. Memory T cell development in the absence of specific antigen priming. J. Immunol. 157:1996;5300-5307.
21. Zhou T., Weaver C., Linsley P.S., Mountz J.D. T cells of staphylococcal enterotoxin B-tolerized autoimmune MRL-lpr/lpr mice require co-stimulation through the B7-CD28/CTLA-4 pathway for activation and can be reanergized in vivo by stimulation of the T cell receptor in the absence of this co-stimulatory signal. Eur. J. Immunol. 24:1994;1019-1025.
22. Lyons A.B., Parish C.R. Determination of lymphocyte division by flow cytometry. J. Immunol. Methods. 171:1994;131-137.
23. Prussin C., Metcalfe D.D. Detection of intracytoplasmic cytokine using flow cytometry and directly conjugated anti-cytokine antibodies. J. Immunol. Methods. 188:1995;117-128.
24. Kearney E.R., Pape K.A., Loh D.Y., Jenkins M.K. Visualization of peptide-specific immunity and peripheral tolerance induction in vivo. Immunity. 1:1994;327-339.
25. Lee W.T., Shiledar-Baxi V., Winslow G.M., Mix D., Murphy D.B. Self-restricted dual receptor memory T cells. J. Immunol. 161:1998;4513-4519.
26. Lee W.T., Vitetta E.S. The differential expression of homing and adhesion molecules on virgin and memory T cells in the mouse. Cell. Immunol. 132:1991;215-222.
27. + T cells from young and aged mice. J. Immunol. 145:1990;1295-1302.
28. Farber D.L., Luqman M., Acuto O., Bottomly K. Control of memory CD4 T cell activation: MHC class II molecules on APCs and CD4 ligation inhibit memory but not naive CD4 cells. Immunity. 2:1995;249-259.
29. Farber D.L. Cutting edge commentary: differential TCR signaling and the generation of memory T cells. J. Immunol. 160:1998;535-539.
30. Byrne J.A., Butler J.L., Cooper M.D. Differential activation requirements for virgin and memory T cells. J. Immunol. 141:1988;3249-3257.
31. hi T lymphocytes accumulate with age in mice and respond poorly to concanavalin A. Eur. J. Immunol. 19:1989;977-982.
32. + T cells. Cell. Immunol. 188:1998;1-11.
33. Lee W.T., Thrush G.R., Vitetta E.S. Staphylococcal enterotoxin B induces the expression of activation markers on murine memory T cells in the absence of proliferation or lymphokine secretion. Cell. Immunol. 162:1995;26-32.
34. Carter L.L., Swain S.L. From naive to memory. Development and regulation of CD4+ T cell responses. Immunol. Res. 18:1998;1-13.
35. + T cell clonal expansion. J. Immunol. 168:2002;1682-1689.
36. Metz D.P., Bottomly K. Function and regulation of memory CD4 T cells. Immunol. Res. 19:1999;127-141.
37. Renno T., Acha-Orbea H. Superantigens in autoimmune diseases: still more shades of gray. Immunol. Rev. 154:1996;175-191.
38. Das M.R.P., Cohen A., Zamvil S.S., Offner H., Kuchroo V.K. Prior exposure to superantigen can inhibit or exacerbate autoimmune encephalomyelitis: T-cell repertoire engaged by the autoantigen determines clinical outcome. J. Neuroimmunol. 71:1996;3-10.
39. Kuschnaroff L.M., Overbergh L., Sefriouni H., Sobis H., Vandeputte M., Waer M. Effect of staphylococcal enterotoxin B injection on the development of experimental autoimmune encephalomyelitis: influence of cytokine and inducible nitric oxide synthase production. J. Neuroimmunol. 99:1999;157-168.
40. Soos J.M., Mujtaba M.G., Schiffenbauer J., Torres B.A., Johnson H.M. Intramolecular epitope spreading induced by staphylococcal enterotoxin superantigen reactivation of experimental allergic encephalomyelitis. J. Neuroimmunol. 123:2002;30-34.
41. Coppola M.A., Blackman M.A. Bacterial superantigens reactivate antigen-specific CD8+ memory T cells. Int. Immunol. 9:1997;1393-1403.
42. Llewelyn M., Cohen J. Superantigens: microbial agents that corrupt immunity. Lancet Infect. Dis. 2:2002;156-162.
43. Woodland D.L. Immunity and retroviral superantigens in humans. Trends Immunol. 23:2002;57-58.