From naive to memory. Development and regulation of CD4+ T cell responses

Immunologic Research

Volumn 18, Issue 1, 1998, Pages 1-13

  Carter, Laura L ^a   Swain, Susan L ^a  

^a TRUDEAU INSTITUTE   (United States)

Author keywords

Apoptosis; CD4+ T cells; Costimulation; Cytokines; Memory

Indexed keywords

CD4 ANTIGEN; CYTOKINE; T LYMPHOCYTE RECEPTOR;

ARTICLE; EFFECTOR CELL; IMMUNOLOGICAL MEMORY; IMMUNOREGULATION; MEMORY CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE; TRANSGENIC MOUSE;

EID: 0031691211     PISSN: 0257277X     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02786509     Document Type: Article

References (15)

1. Mosmann TR, Sad S. The expanding universe of T-cell subsets: Th1, Th2 and nore. Immunol Today 1996;17(3):138-146.
2. Constant SL, Bottomley K. Induction of the Th1 and Th2 CD4+ Tcell responses: alternative approaches. Annu Rev Immunol 1997;15:297-322.
3. Swain SL, Croft M, Dubey C, Haynes L, Rogers P, Zhang X, et al. From naive to memory T cells. Immunol Rev 1996;150:143-167.
4. Swain SL. Generation and in vivo persistance of polarized Th1 and Th2 memory cells. Immunity 1994;1:543-552.
5. Dubey CM, Croft M, Swain SL. Costimulatory requirements of naive CD4+ T cells. ICAM-1 or B7-1 can costimulate naive CD4T cell activation but both are required for optimum response. J Immunol 1995;155:45-57.
6. Zhang X, Brunner T, Carter L, Dutton RW, Rogers P, Bradley L, et al. Unequal death in Th1 and Th2 effectors: Th1 but not Th2 effectors undergo rapid Fas/FasL-mediated apoptosis. J Exp Med 1997;185:1837-1849.
7. Luqman M, Bottomley K. Activation requirements for CD4+ T cells differing in CD45R expression. J Immunol 1992;149:2300.
8. Dubey CM, Croft M, Swain SL. Naive and effector CD4 T cells differ in their requirement for T cell receptor versus costimulatory signals. J Immunol 1996;157:3280-3289.
9. Nagata S, Golstein P. The Fas death factor. Science 1994;267:1449
10. Sato T, Irie S, Kitada S, Reed JC. FAP-1: a protein tyrosine phosphatase that associates with Fas. Science 1995;268:411-415.
11. Zhang X, Giangreco L, Broome HE, Dargan CM, Swain SL. Control of CD4 effector fate: transforming growth factor beta-1 and interleukin-2 synergize to prevent apoptosis and promote effector expansion. J Exp Med 1995; 182:699-709.
12. Lenardo MJ. Interleukin-2 programs mouse aB lymphocytes for apoptosis. 1991;353:858-862.
13. Lau LL, Jamieson BD, Somasundaram T, Ahmed R. Cytotoxic T cell memory without antigen. Nature 1994;369:648-652
14. Zhang X, Rogers P, Dubey C, Swain SL. Effector to memory T cells transition results in resistance to activation induced cell death. Manuscript in preparation.
15. Rogers PR, Zhang X, Swain SL. Antigen dose and effector polarization in vitro: contribution of greater Th1 death to Th2 predominance. Manuscript in preparation.