-
1
-
-
0026717674
-
The pathophysiology of tumor necrosis factors
-
Vassalli P: The pathophysiology of tumor necrosis factors. Annu Rev Immunol 10:411, 1992.
-
(1992)
Annu Rev Immunol
, vol.10
, pp. 411
-
-
Vassalli, P.1
-
2
-
-
0029319901
-
TNF, immunity and inflammatory disease: Lessons of the past decade
-
Beutler B: TNF, immunity and inflammatory disease: lessons of the past decade. J Investig Med 43:227, 1995.
-
(1995)
J Investig Med
, vol.43
, pp. 227
-
-
Beutler, B.1
-
3
-
-
0023601773
-
Human tumor necrosis factor potentiates human interleukin 1-mediated rat pancreatic beta-cell cytotoxicity
-
Mandrup-Poulsen T, Bendtzen K, Dinarello CA, Nerup J: Human tumor necrosis factor potentiates human interleukin 1-mediated rat pancreatic beta-cell cytotoxicity. J Immunol 139:4077, 1987.
-
(1987)
J Immunol
, vol.139
, pp. 4077
-
-
Mandrup-Poulsen, T.1
Bendtzen, K.2
Dinarello, C.A.3
Nerup, J.4
-
4
-
-
0028900805
-
Intraislet release of interleukin 1 inhibits beta cell function by inducing beta cell expression of inducible nitric oxide synthase
-
Corbett JA, McDaniel ML: Intraislet release of interleukin 1 inhibits beta cell function by inducing beta cell expression of inducible nitric oxide synthase. J Exp Med 181:559, 1995.
-
(1995)
J Exp Med
, vol.181
, pp. 559
-
-
Corbett, J.A.1
McDaniel, M.L.2
-
5
-
-
0029922662
-
Strain-dependent differences in sensitivity of rat beta-cells to interleukin 1 beta in vitro and in vivo: Association with islet nitric oxide synthesis
-
Reimers JI, Andersen HU, Mauricio D, Pociot F, Karlsen AE, Petersen JS, Mandrup-Poulsen T, Nerup J: Strain-dependent differences in sensitivity of rat beta-cells to interleukin 1 beta in vitro and in vivo: association with islet nitric oxide synthesis. Diabetes 45:771, 1996.
-
(1996)
Diabetes
, vol.45
, pp. 771
-
-
Reimers, J.I.1
Andersen, H.U.2
Mauricio, D.3
Pociot, F.4
Karlsen, A.E.5
Petersen, J.S.6
Mandrup-Poulsen, T.7
Nerup, J.8
-
6
-
-
0032523104
-
Cytokines and their roles in pancreatic islet beta-cell destruction and insulin-dependent diabetes mellitus
-
Rabinovitch A, Suarez-Pinzon WL: Cytokines and their roles in pancreatic islet beta-cell destruction and insulin-dependent diabetes mellitus. Biochem Pharmacol 55:1139, 1998.
-
(1998)
Biochem Pharmacol
, vol.55
, pp. 1139
-
-
Rabinovitch, A.1
Suarez-Pinzon, W.L.2
-
7
-
-
0025020303
-
Prevention of diabetes in nonobese diabetic mice by tumor necrosis factor (TNF): Similarities between TNF-alpha and interleukin 1
-
Jacob CO, Aiso S, Michie SA, McDevitt HO, Acha-Orbea H: Prevention of diabetes in nonobese diabetic mice by tumor necrosis factor (TNF): similarities between TNF-alpha and interleukin 1. Proc Natl Acad Sci U S A 87:968, 1990.
-
(1990)
Proc Natl Acad Sci U S A
, vol.87
, pp. 968
-
-
Jacob, C.O.1
Aiso, S.2
Michie, S.A.3
McDevitt, H.O.4
Acha-Orbea, H.5
-
8
-
-
0025016823
-
Heritable major histocompatibility complex class II-associated differences in production of tumor necrosis factor alpha: Relevance to genetic predisposition to systemic lupus erythematosus
-
Jacob CO, Fronek Z, Lewis GD, Koo M, Hansen JA, McDevitt HO: Heritable major histocompatibility complex class II-associated differences in production of tumor necrosis factor alpha: relevance to genetic predisposition to systemic lupus erythematosus. Proc Natl Acad Sci U S A 87:1233, 1990.
-
(1990)
Proc Natl Acad Sci U S A
, vol.87
, pp. 1233
-
-
Jacob, C.O.1
Fronek, Z.2
Lewis, G.D.3
Koo, M.4
Hansen, J.A.5
McDevitt, H.O.6
-
9
-
-
0027207669
-
Transgenic tumor necrosis factor (TNF)-alpha production in pancreatic islets leads to insulitis, not diabetes. Distinct patterns of inflammation in TNF-alpha and TNF-beta transgenic mice
-
Picarella DE, Kratz A, Li CB, Ruddle NH, Flavell RA: Transgenic tumor necrosis factor (TNF)-alpha production in pancreatic islets leads to insulitis, not diabetes. Distinct patterns of inflammation in TNF-alpha and TNF-beta transgenic mice. J Immunol 150:4136, 1993.
-
(1993)
J Immunol
, vol.150
, pp. 4136
-
-
Picarella, D.E.1
Kratz, A.2
Li, C.B.3
Ruddle, N.H.4
Flavell, R.A.5
-
10
-
-
0028143212
-
Repeated therapy with monoclonal antibody to tumour necrosis factor alpha (cA2) in patients with rheumatoid arthritis
-
Elliott MJ, Maini RN, Feldmann M, Long-Fox A, Charles P, Bijl H, Woody JN: Repeated therapy with monoclonal antibody to tumour necrosis factor alpha (cA2) in patients with rheumatoid arthritis. Lancet 344:1125, 1994.
-
(1994)
Lancet
, vol.344
, pp. 1125
-
-
Elliott, M.J.1
Maini, R.N.2
Feldmann, M.3
Long-Fox, A.4
Charles, P.5
Bijl, H.6
Woody, J.N.7
-
11
-
-
0028985199
-
Accelerated beta-cell destruction in adoptively transferred autoimmune diabetes correlates with an increased expression of the genes coding for TNF-alpha and granzyme A in the intra-islet infiltrates
-
Mueller C, Held W, Imboden MA, Carnaud C: Accelerated beta-cell destruction in adoptively transferred autoimmune diabetes correlates with an increased expression of the genes coding for TNF-alpha and granzyme A in the intra-islet infiltrates. Diabetes 44:112, 1995.
-
(1995)
Diabetes
, vol.44
, pp. 112
-
-
Mueller, C.1
Held, W.2
Imboden, M.A.3
Carnaud, C.4
-
12
-
-
0033512202
-
Identification of a genetic risk factor for systemic juvenile rheumatoid arthritis in the 5′-flanking region of the TNFalpha gene and HLA genes
-
Date Y, Seki N, Kamizono S, Higuchi T, Hirata T, Miyata K, Ohkuni M, Tatsuzawa O, Yokota S, Joo K, Ueda K, Sasazuki T, Kimura A, Itoh K, Kato H: Identification of a genetic risk factor for systemic juvenile rheumatoid arthritis in the 5′-flanking region of the TNFalpha gene and HLA genes. Arthritis Rheum 42:2577, 1999.
-
(1999)
Arthritis Rheum
, vol.42
, pp. 2577
-
-
Date, Y.1
Seki, N.2
Kamizono, S.3
Higuchi, T.4
Hirata, T.5
Miyata, K.6
Ohkuni, M.7
Tatsuzawa, O.8
Yokota, S.9
Joo, K.10
Ueda, K.11
Sasazuki, T.12
Kimura, A.13
Itoh, K.14
Kato, H.15
-
13
-
-
0032827184
-
Polymorphism of the 5′-flanking region of the tumor necrosis factor (TNF)-alpha gene and susceptibility to human T-cell lymphotropic virus type 1 (HTLV-I) uveitis
-
Seki N, Yamaguchi K, Yamada A, Kamizono S, Sugita S, Taguchi C, Matsuoka M, Matsumoto H, Nishizaka S, Itoh K, Mochizuki M: Polymorphism of the 5′-flanking region of the tumor necrosis factor (TNF)-alpha gene and susceptibility to human T-cell lymphotropic virus type 1 (HTLV-I) uveitis. J Infect Dis 180:880, 1999.
-
(1999)
J Infect Dis
, vol.180
, pp. 880
-
-
Seki, N.1
Yamaguchi, K.2
Yamada, A.3
Kamizono, S.4
Sugita, S.5
Taguchi, C.6
Matsuoka, M.7
Matsumoto, H.8
Nishizaka, S.9
Itoh, K.10
Mochizuki, M.11
-
14
-
-
0034252209
-
Independent contribution of HLA-DRB1 and TNF alpha promoter polymorphisms to the susceptibility to Crohn's disease
-
Kawasaki A, Tsuchiya N, Hagiwara K, Takazoe M, Tokunaga K: Independent contribution of HLA-DRB1 and TNF alpha promoter polymorphisms to the susceptibility to Crohn's disease. Genes Immun 1:351, 2000.
-
(2000)
Genes Immun
, vol.1
, pp. 351
-
-
Kawasaki, A.1
Tsuchiya, N.2
Hagiwara, K.3
Takazoe, M.4
Tokunaga, K.5
-
15
-
-
0025921292
-
HLA-DQA1*1 contributes to resistance and A1*3 confers susceptibility to type 1 (insulin-dependent) diabetes mellitus in Japanese subjects
-
Yamagata K, Hanafusa T, Nakajima H, Sada M, Amemiya H, Noguchi T, Tanaka T, Kono N, Tarui S: HLA-DQA1*1 contributes to resistance and A1*3 confers susceptibility to type 1 (insulin-dependent) diabetes mellitus in Japanese subjects. Diabetologia 34:133, 1991.
-
(1991)
Diabetologia
, vol.34
, pp. 133
-
-
Yamagata, K.1
Hanafusa, T.2
Nakajima, H.3
Sada, M.4
Amemiya, H.5
Noguchi, T.6
Tanaka, T.7
Kono, N.8
Tarui, S.9
-
16
-
-
0026554270
-
Genetic analysis of HLA class 11 alleles and susceptibility to type 1 (insulin-dependent) diabetes mellitus in Japanese subjects
-
Awata T, Kuzuya T, Matsuda A, Iwamoto Y, Kanazawa Y: Genetic analysis of HLA class 11 alleles and susceptibility to type 1 (insulin-dependent) diabetes mellitus in Japanese subjects. Diabetologia 35:419, 1992.
-
(1992)
Diabetologia
, vol.35
, pp. 419
-
-
Awata, T.1
Kuzuya, T.2
Matsuda, A.3
Iwamoto, Y.4
Kanazawa, Y.5
-
17
-
-
0027238178
-
Particular HLA-DQ molecules play a dominant role in determining susceptibility or resistance to type 1 (insulin-dependent) diabetes mellitus
-
Thorsby E, Ronningen KS: Particular HLA-DQ molecules play a dominant role in determining susceptibility or resistance to type 1 (insulin-dependent) diabetes mellitus. Diabetologia 36:371, 1993.
-
(1993)
Diabetologia
, vol.36
, pp. 371
-
-
Thorsby, E.1
Ronningen, K.S.2
-
18
-
-
0027434873
-
No independent association between a tumor necrosis factor-alpha promotor region polymorphism and insulin-dependent diabetes mellitus
-
Pociot F, Wilson AG, Nerup J, Duff GW: No independent association between a tumor necrosis factor-alpha promotor region polymorphism and insulin-dependent diabetes mellitus. Eur J Immunol 23:3050, 1993.
-
(1993)
Eur J Immunol
, vol.23
, pp. 3050
-
-
Pociot, F.1
Wilson, A.G.2
Nerup, J.3
Duff, G.W.4
-
19
-
-
0006747979
-
TNFa microsatellite polymorphism modulates the risk of IDDM in Caucasians with the high-risk genotype HLA DQA1*0501-DQB1*0201/DQA1*0301-DQB1* 0302
-
Belgian Diabetes Registry
-
Moghaddam PH, Zwinderman AH, de Knijff P, Roep BO, Schipper RF, Van der Auwera B, Naipal A, Gorus F, Schuit F, Giphart MJ: TNFa microsatellite polymorphism modulates the risk of IDDM in Caucasians with the high-risk genotype HLA DQA1*0501-DQB1*0201/DQA1*0301-DQB1*0302. Belgian Diabetes Registry. Diabetes 46:1514, 1997.
-
(1997)
Diabetes
, vol.46
, pp. 1514
-
-
Moghaddam, P.H.1
Zwinderman, A.H.2
De Knijff, P.3
Roep, B.O.4
Schipper, R.F.5
Van der Auwera, B.6
Naipal, A.7
Gorus, F.8
Schuit, F.9
Giphart, M.J.10
-
20
-
-
0029814642
-
A new TNFA promoter allele identified in South American Blacks
-
Zimmerman PA, Guderian RH, Nutman TB: A new TNFA promoter allele identified in South American Blacks. Immunogenetics 44:485, 1996.
-
(1996)
Immunogenetics
, vol.44
, pp. 485
-
-
Zimmerman, P.A.1
Guderian, R.H.2
Nutman, T.B.3
-
21
-
-
0031747683
-
Polymorphism of the 5′-flanking region of the human tumor necrosis factor (TNF)-alpha gene in Japanese
-
Higuchi T, Seki N, Kamizono S, Yamada A, Kimura A, Kato H, Itoh K: Polymorphism of the 5′-flanking region of the human tumor necrosis factor (TNF)-alpha gene in Japanese. Tissue Antigens 51:605, 1998.
-
(1998)
Tissue Antigens
, vol.51
, pp. 605
-
-
Higuchi, T.1
Seki, N.2
Kamizono, S.3
Yamada, A.4
Kimura, A.5
Kato, H.6
Itoh, K.7
-
22
-
-
0032436712
-
Functional analysis of a human tumor necrosis factor alpha (TNF-alpha) promoter polymorphism related to joint damage in rheumatoid arthritis
-
Kaijzel EL, van Krugten MV, Brinkman BM, Huizinga TW, van der Straaten T, Hazes JM, Ziegler-Heitbrock HW, Nedospasov SA, Breedveld FC, Verweij CL: Functional analysis of a human tumor necrosis factor alpha (TNF-alpha) promoter polymorphism related to joint damage in rheumatoid arthritis. Mol Med 4:724, 1998.
-
(1998)
Mol Med
, vol.4
, pp. 724
-
-
Kaijzel, E.L.1
Van Krugten, M.V.2
Brinkman, B.M.3
Huizinga, T.W.4
Van der Straaten, T.5
Hazes, J.M.6
Ziegler-Heitbrock, H.W.7
Nedospasov, S.A.8
Breedveld, F.C.9
Verweij, C.L.10
-
23
-
-
0028979244
-
Genetic variability in the TNF-alpha promoter is not associated with type II diabetes mellitus (NIDDM)
-
Hamann A, Mantzoros C, Vidal-Puig A, Flier JS: Genetic variability in the TNF-alpha promoter is not associated with type II diabetes mellitus (NIDDM). Biochem Biophys Res Commun 211:833, 1995.
-
(1995)
Biochem Biophys Res Commun
, vol.211
, pp. 833
-
-
Hamann, A.1
Mantzoros, C.2
Vidal-Puig, A.3
Flier, J.S.4
-
24
-
-
0031719942
-
Identification of three new single nucleotide polymorphisms in the human tumor necrosis factor-alpha gene promoter
-
Uglialoro AM, Turbay D, Pesavento PA, Delgado JC, McKenzie FE, Gribben JG, Hartl D, Yunis EJ, Goldfeld AE: Identification of three new single nucleotide polymorphisms in the human tumor necrosis factor-alpha gene promoter. Tissue Antigens 52:359, 1998.
-
(1998)
Tissue Antigens
, vol.52
, pp. 359
-
-
Uglialoro, A.M.1
Turbay, D.2
Pesavento, P.A.3
Delgado, J.C.4
McKenzie, F.E.5
Gribben, J.G.6
Hartl, D.7
Yunis, E.J.8
Goldfeld, A.E.9
-
25
-
-
0033979837
-
Analysis of tumor necrosis factor-alpha promoter polymorphism in type 1 diabetes: HLA-B and -DRB 1 alleles are primarily associated with the disease in Japanese
-
Hamaguchi K, Kimura A, Seki N, Higuchi T, Yasunaga S, Takahashi M, Sasazuki T, Kusuda Y, Okeda T, Itoh K, Sakata T: Analysis of tumor necrosis factor-alpha promoter polymorphism in type 1 diabetes: HLA-B and -DRB1 alleles are primarily associated with the disease in Japanese. Tissue Antigens 55:10, 2000.
-
(2000)
Tissue Antigens
, vol.55
, pp. 10
-
-
Hamaguchi, K.1
Kimura, A.2
Seki, N.3
Higuchi, T.4
Yasunaga, S.5
Takahashi, M.6
Sasazuki, T.7
Kusuda, Y.8
Okeda, T.9
Itoh, K.10
Sakata, T.11
-
26
-
-
0031851293
-
Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: Diagnosis and classification of diabetes mellitus provisional report of a WHO consultation
-
Alberti KG, Zimmet PZ: Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus provisional report of a WHO consultation. Diabet Med 15:539, 1998.
-
(1998)
Diabet Med
, vol.15
, pp. 539
-
-
Alberti, K.G.1
Zimmet, P.Z.2
-
27
-
-
0031308972
-
Molecular epidemiology of insulin-dependent diabetes mellitus: WHO DiaMond Project
-
WHO DiaMond Molecular Epidemiology Sub-Project Group
-
Dorman J: Molecular epidemiology of insulin-dependent diabetes mellitus: WHO DiaMond Project. WHO DiaMond Molecular Epidemiology Sub-Project Group. Gac Med Mex 133(Suppl 1):151, 1997.
-
(1997)
Gac Med Mex
, vol.133
, Issue.SUPPL. 1
, pp. 151
-
-
Dorman, J.1
-
28
-
-
0027195760
-
HLA-DQB1 and -DQA1 typing by PCR amplification with sequence-specific primers (PCR-SSP) in 2 hours
-
Olerup O, Aldener A, Fogdell A: HLA-DQB1 and -DQA1 typing by PCR amplification with sequence-specific primers (PCR-SSP) in 2 hours. Tissue Antigens 41: 119, 1993.
-
(1993)
Tissue Antigens
, vol.41
, pp. 119
-
-
Olerup, O.1
Aldener, A.2
Fogdell, A.3
-
29
-
-
0029618012
-
Phototyping: Comprehensive DNA typing for HLA-A, B, C, DRB1, DRB3, DRB4, DRB5 & DQB1 by PCR with 144 primer mixes utilizing sequence-specific primers (PCR-SSP)
-
Bunce M, O'Neill CM, Barnardo MC, Krausa P, Browning MJ, Morris PJ, Welsh KI: Phototyping: comprehensive DNA typing for HLA-A, B, C, DRB1, DRB3, DRB4, DRB5 & DQB1 by PCR with 144 primer mixes utilizing sequence-specific primers (PCR-SSP). Tissue Antigens 46:355, 1995.
-
(1995)
Tissue Antigens
, vol.46
, pp. 355
-
-
Bunce, M.1
O'Neill, C.M.2
Barnardo, M.C.3
Krausa, P.4
Browning, M.J.5
Morris, P.J.6
Welsh, K.I.7
-
30
-
-
0032837736
-
A common functional polymorphism (C->A substitution at position -863) in the promoter region of the tumour necrosis factor-alpha (TNF-alpha) gene associated with reduced circulating levels of TNF-alpha
-
Skoog T, van't Hooft FM, Kallin B, Jovinge S, Boquist S, Nilsson J, Eriksson P, Hamsten A: A common functional polymorphism (C->A substitution at position -863) in the promoter region of the tumour necrosis factor-alpha (TNF-alpha) gene associated with reduced circulating levels of TNF-alpha. Hum Mol Genet 8:1443, 1999.
-
(1999)
Hum Mol Genet
, vol.8
, pp. 1443
-
-
Skoog, T.1
Van't Hooft, F.M.2
Kallin, B.3
Jovinge, S.4
Boquist, S.5
Nilsson, J.6
Eriksson, P.7
Hamsten, A.8
-
31
-
-
0033814928
-
Implementing a unified approach to family-based tests of association
-
Laird NM, Horvath S, Xu X: Implementing a unified approach to family-based tests of association. Genet Epidemiol 19(Suppl 1):S36, 2000.
-
(2000)
Genet Epidemiol
, vol.19
, Issue.SUPPL. 1
-
-
Laird, N.M.1
Horvath, S.2
Xu, X.3
-
32
-
-
0035055544
-
The family based association test method: Strategies for studying general genotypephenotype associations
-
Horvath S, Xu X, Laird NM: The family based association test method: strategies for studying general genotypephenotype associations. Eur J Hum Genet 9:301, 2001.
-
(2001)
Eur J Hum Genet
, vol.9
, pp. 301
-
-
Horvath, S.1
Xu, X.2
Laird, N.M.3
-
33
-
-
0027377799
-
Transmission test for linkage disequilibrium: The insulin gene region and insulin-dependent diabetes mellitus (IDDM)
-
Spielman RS, McGinnis RE, Ewens WJ: Transmission test for linkage disequilibrium: the insulin gene region and insulin-dependent diabetes mellitus (IDDM). Am J Hum Genet 52:506, 1993.
-
(1993)
Am J Hum Genet
, vol.52
, pp. 506
-
-
Spielman, R.S.1
McGinnis, R.E.2
Ewens, W.J.3
-
34
-
-
0034026635
-
Susceptible locus for obese type 2 diabetes mellitus in the 5′-flanking region of the tumor necrosis factor-alpha gene
-
Kamizono S, Yamada K, Seki N, Higuchi T, Kimura A, Nonaka K, Itoh K: Susceptible locus for obese type 2 diabetes mellitus in the 5′-flanking region of the tumor necrosis factor-alpha gene. Tissue Antigens 55:449, 2000.
-
(2000)
Tissue Antigens
, vol.55
, pp. 449
-
-
Kamizono, S.1
Yamada, K.2
Seki, N.3
Higuchi, T.4
Kimura, A.5
Nonaka, K.6
Itoh, K.7
-
35
-
-
0141574379
-
Host and environmental factors defining the epidemiology of type 1 diabetes in a group of Lebanese children and young adults
-
in press
-
Zalloua PA, Terwedow H, Shbaklo H, Halaby G, Xu X, Azar ST: Host and Environmental Factors Defining the Epidemiology of Type 1 Diabetes in a Group of Lebanese Children and Young Adults. J Pediatr Endocrinol Metab in press, 2003.
-
(2003)
J Pediatr Endocrinol Metab
-
-
Zalloua, P.A.1
Terwedow, H.2
Shbaklo, H.3
Halaby, G.4
Xu, X.5
Azar, S.T.6
-
36
-
-
0032106026
-
High glucose concentrations increase the tumor necrosis factor-alpha production capacity by human peripheral blood mononuclear cells
-
Hancu N, Netea MG, Baciu I: High glucose concentrations increase the tumor necrosis factor-alpha production capacity by human peripheral blood mononuclear cells. Rom J Physiol 35:325, 1998.
-
(1998)
Rom J Physiol
, vol.35
, pp. 325
-
-
Hancu, N.1
Netea, M.G.2
Baciu, I.3
-
37
-
-
0032440132
-
Tumour necrosis factor alfa and glucose levels in sera of mice infected with coxsackie B4 and A7 viruses
-
Bopegamage SA, Petrovicova A: Tumour necrosis factor alfa and glucose levels in sera of mice infected with coxsackie B4 and A7 viruses. Acta Virol 42:409, 1998.
-
(1998)
Acta Virol
, vol.42
, pp. 409
-
-
Bopegamage, S.A.1
Petrovicova, A.2
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