-
1
-
-
0028143211
-
Randomised double-blind comparison of chimeric monoclonal antibody to tumour necrosis factor a (cA2) versus placebo in rheumatoid arthritis
-
Elliott MJ, Maini R, Feldmann M, et al. (1994) Randomised double-blind comparison of chimeric monoclonal antibody to tumour necrosis factor a (cA2) versus placebo in rheumatoid arthritis. Lancet 344: 1105-1110.
-
(1994)
Lancet
, vol.344
, pp. 1105-1110
-
-
Elliott, M.J.1
Maini, R.2
Feldmann, M.3
-
2
-
-
0028143212
-
Repeated therapy with monoclonal antibody to tumour necrosis factor α (cA2) in patients with rheumatoid arthritis
-
Elliott MJ, Maini RN, Feldmann M, et al. (1994) Repeated therapy with monoclonal antibody to tumour necrosis factor α (cA2) in patients with rheumatoid arthritis. Lancet 344: 1125-1127.
-
(1994)
Lancet
, vol.344
, pp. 1125-1127
-
-
Elliott, M.J.1
Maini, R.N.2
Feldmann, M.3
-
3
-
-
0026039673
-
Transgenic mice expressing human tumour necrosis factor: A predictive genetic model of arthritis
-
Keffer J, Probert L, Cazlaris H, Georgopoulos S, Kaslaris E, Kioussis D, Kollias G. (1991) Transgenic mice expressing human tumour necrosis factor: a predictive genetic model of arthritis. EMBO J. 10: 4025-4031.
-
(1991)
EMBO J.
, vol.10
, pp. 4025-4031
-
-
Keffer, J.1
Probert, L.2
Cazlaris, H.3
Georgopoulos, S.4
Kaslaris, E.5
Kioussis, D.6
Kollias, G.7
-
4
-
-
0345609037
-
Characterization of tumor necrosis factor-deficient mice
-
Marino MW, Dunn A, Grail D, et al. (1997) Characterization of tumor necrosis factor-deficient mice. Proc. Natl. Acad. Sci. U.S.A. 94: 8093-8098.
-
(1997)
Proc. Natl. Acad. Sci. U.S.A.
, vol.94
, pp. 8093-8098
-
-
Marino, M.W.1
Dunn, A.2
Grail, D.3
-
5
-
-
0030898333
-
Mice heterozygous for a deletion of the tumor necrosis factor-α and lymphotoxin-α genes: Biological importance of a non-linear response of tumor necrosis factor-α to gene dosage
-
Amiot F, Boussadia O, Cases S, et al. (1997) Mice heterozygous for a deletion of the tumor necrosis factor-α and lymphotoxin-α genes: biological importance of a non-linear response of tumor necrosis factor-α to gene dosage. Eur. J. Immunol. 27: 1035-1042.
-
(1997)
Eur. J. Immunol.
, vol.27
, pp. 1035-1042
-
-
Amiot, F.1
Boussadia, O.2
Cases, S.3
-
6
-
-
0024372012
-
Genetic analysis of the human tumor necrosis factor α/cachectin promoter region in a macrophage cell line
-
Economou JS, Rhoades K, Essner R, McBride WH, Gasson JC, Morton D. (1989) Genetic analysis of the human tumor necrosis factor α/cachectin promoter region in a macrophage cell line. J. Exp. Med. 170: 321-326.
-
(1989)
J. Exp. Med.
, vol.170
, pp. 321-326
-
-
Economou, J.S.1
Rhoades, K.2
Essner, R.3
McBride, W.H.4
Gasson, J.C.5
Morton, D.6
-
7
-
-
0025607864
-
Human tumor necrosis factor α gene regulation by virus and lipopolysaccharide
-
Goldfeld AE, Doyle C, Maniatis T. (1990) Human tumor necrosis factor α gene regulation by virus and lipopolysaccharide. Proc. Natl. Acad. Sci. U.S.A. 87: 9769-9773.
-
(1990)
Proc. Natl. Acad. Sci. U.S.A.
, vol.87
, pp. 9769-9773
-
-
Goldfeld, A.E.1
Doyle, C.2
Maniatis, T.3
-
8
-
-
0026512581
-
Application of transcriptional and posttranscriptional reporter constructs to the analysis of tumor necrosis factor gene regulation
-
Beutler B. (1992) Application of transcriptional and posttranscriptional reporter constructs to the analysis of tumor necrosis factor gene regulation. Am. J. Med. Sci. 303: 129-133.
-
(1992)
Am. J. Med. Sci.
, vol.303
, pp. 129-133
-
-
Beutler, B.1
-
9
-
-
0028693764
-
Regulation of the TNFα gene
-
Jongeneel CV. (1994) Regulation of the TNFα gene. Prog. Clin. Biol. Res. 388: 367-381.
-
(1994)
Prog. Clin. Biol. Res.
, vol.388
, pp. 367-381
-
-
Jongeneel, C.V.1
-
10
-
-
0025764433
-
Association of HLA-DR4 with a more progressive disease course in patients with rheumatoid arthritis. Results of a follow-up study
-
van Zeben D, Hazes JMW, Zwinderman AH, et al. (1991) Association of HLA-DR4 with a more progressive disease course in patients with rheumatoid arthritis. Results of a follow-up study. Arthritis Rheum. 43: 822-830.
-
(1991)
Arthritis Rheum.
, vol.43
, pp. 822-830
-
-
Van Zeben, D.1
Jmw, H.2
Zwinderman, A.H.3
-
11
-
-
0028366342
-
A polymorphic variation in a putative regulation box of the TNFA promoter region
-
D'Alfonso S, Momigliano Richiardi P. (1994) A polymorphic variation in a putative regulation box of the TNFA promoter region. Immunogenetics 39: 150-154.
-
(1994)
Immunogenetics
, vol.39
, pp. 150-154
-
-
D'Alfonso, S.1
Momigliano Richiardi, P.2
-
12
-
-
0030810790
-
Tumour necrosis factor a gene polymorphisms in rheumatoid arthritis: Association with susceptibility to, or severity of, disease? Er
-
Brinkman BMN, Huizinga TWJ, Kurban SS, et al. (1997) Tumour necrosis factor a gene polymorphisms in rheumatoid arthritis: association with susceptibility to, or severity of, disease? Er. J. Rheumatol. 36: 516-521.
-
(1997)
J. Rheumatol.
, vol.36
, pp. 516-521
-
-
Bmn, B.1
Twj, H.2
Kurban, S.S.3
-
13
-
-
0031033902
-
Polymorphism at the TNF loci in rheumatoid arthritis
-
Vinasco J, Beraun Y, Nieto A, et al. (1997) Polymorphism at the TNF loci in rheumatoid arthritis. Tissue Antigens 49: 74-78.
-
(1997)
Tissue Antigens
, vol.49
, pp. 74-78
-
-
Vinasco, J.1
Beraun, Y.2
Nieto, A.3
-
14
-
-
0031047430
-
TNF-α polymorphisms, production and susceptibility to multiple sclerosis in different groups of patients
-
Huizinga TWJ, Westendorp RGJ, Bollen ELEM, et al. (1997) TNF-α polymorphisms, production and susceptibility to multiple sclerosis in different groups of patients. J. Neuroimmunol. 72: 149-153.
-
(1997)
J. Neuroimmunol.
, vol.72
, pp. 149-153
-
-
Twj, H.1
Rgj, W.2
Elem, B.3
-
15
-
-
0029810504
-
An intragenic polymorphism in the human tumor necrosis factor alpha (TNFA) chain-encoding gene
-
D'Alfonso S, Momigliano Richiardi P. (1996) An intragenic polymorphism in the human tumor necrosis factor alpha (TNFA) chain-encoding gene. Immunogenetics 44: 321-322.
-
(1996)
Immunogenetics
, vol.44
, pp. 321-322
-
-
D'Alfonso, S.1
Momigliano Richiardi, P.2
-
16
-
-
0030766567
-
A TNF-α promoter polymorphism is associated with juvenile onset psoriasis and psoriatic arthritis
-
Höhler T, Kruger A, Schneider PM, et al. (1997) A TNF-α promoter polymorphism is associated with juvenile onset psoriasis and psoriatic arthritis. J. Invest. Dermatol. 109: 562-565.
-
(1997)
J. Invest. Dermatol.
, vol.109
, pp. 562-565
-
-
Höhler, T.1
Kruger, A.2
Schneider, P.M.3
-
17
-
-
0031030701
-
Scarring trachoma is associated with polymorphism in the tumor necrosis factor alpha (TNF-α) gene promoter and with elevated TNF-α levels in tear fluid
-
Conway DJ, Holland MJ, Bailey RL, et al. (1997) Scarring trachoma is associated with polymorphism in the tumor necrosis factor alpha (TNF-α) gene promoter and with elevated TNF-α levels in tear fluid. Infection Immunity 65: 1003-1006.
-
(1997)
Infection Immunity
, vol.65
, pp. 1003-1006
-
-
Conway, D.J.1
Holland, M.J.2
Bailey, R.L.3
-
18
-
-
0031009602
-
Association of a tumor necrosis factor promoter polymorphism with susceptibility to alcoholic steatohepatitis
-
Grove J, Daly AK, Bassendine MF, Day CP. (1997) Association of a tumor necrosis factor promoter polymorphism with susceptibility to alcoholic steatohepatitis. Hepatology 26: 143-146.
-
(1997)
Hepatology
, vol.26
, pp. 143-146
-
-
Grove, J.1
Daly, A.K.2
Bassendine, M.F.3
Day, C.P.4
-
19
-
-
0028065317
-
The severity of rheumatoid arthritis: A 6-year follow-up study of younger women with symptoms of recent onset
-
van Zeben D, Hazes JM, Zwinderman AH, Vandenbroucke JP, Breedveld FC. (1994) The severity of rheumatoid arthritis: a 6-year follow-up study of younger women with symptoms of recent onset. J. Rheumatol. 21: 1620-1625.
-
(1994)
J. Rheumatol.
, vol.21
, pp. 1620-1625
-
-
Zeben, D.1
Hazes, J.M.2
Zwinderman, A.H.3
Vandenbroucke, J.P.4
Breedveld, F.C.5
-
20
-
-
0023945481
-
The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis
-
Arnett FC, Edworthy SM, Bloch DA, et al. (1988) The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum. 31: 315-324.
-
(1988)
Arthritis Rheum.
, vol.31
, pp. 315-324
-
-
Arnett, F.C.1
Edworthy, S.M.2
Bloch, D.A.3
-
21
-
-
0029091107
-
Radiographie progression on radiographs of hands and feet during the first 3 years of rheumatoid arthritis measured according to Sharp's method (van der Heijde's modification)
-
van der Heijde DM, van Leeuwen MA, van Riel PL, van de Putte LB. (1995) Radiographie progression on radiographs of hands and feet during the first 3 years of rheumatoid arthritis measured according to Sharp's method (van der Heijde's modification). J. Rheumatol. 22: 1792-1796.
-
(1995)
J. Rheumatol.
, vol.22
, pp. 1792-1796
-
-
Van Der Heijde, D.M.1
Van Ma, L.2
Van Riel, P.L.3
Van De Putte, L.B.4
-
22
-
-
0029966034
-
Relevance of the tumor necrosis factor alpha (TNFα) -308 promoter polymorphism in TNFa gene regulation
-
Brinkman BMN, Zuijdgeest D, Kaijzel EL, Breedveld FC, Verweij CL. (1996) Relevance of the tumor necrosis factor alpha (TNFα) -308 promoter polymorphism in TNFa gene regulation. J. Imflam. 46: 32-41.
-
(1996)
J. Imflam.
, vol.46
, pp. 32-41
-
-
Bmn, B.1
Zuijdgeest, D.2
Kaijzel, E.L.3
Breedveld, F.C.4
Verweij, C.L.5
-
23
-
-
0024002556
-
Luciferase reporter gene vectors for analysis of promoters and enhancers
-
Nordeen SK. (1988) Luciferase reporter gene vectors for analysis of promoters and enhancers. BioTechniques 6: 454-457.
-
(1988)
BioTechniques
, vol.6
, pp. 454-457
-
-
Nordeen, S.K.1
-
25
-
-
0017155490
-
Establishment and characterization of a human histiocytic cell line (U-937)
-
Sundstrom C, Nilsson K. (1976) Establishment and characterization of a human histiocytic cell line (U-937). M. J. Cancer 17: 565-577.
-
(1976)
M. J. Cancer
, vol.17
, pp. 565-577
-
-
Sundstrom, C.1
Nilsson, K.2
-
26
-
-
0023878330
-
Establishment of a human cell line (Mono Mac 6) with characteristics of mature monocytes
-
Ziegler-Heitbrock HWL, Thiel E, Fütterer A, Herzog V, Wirtz A, Riethmüller G. (1988) Establishment of a human cell line (Mono Mac 6) with characteristics of mature monocytes. Int. J. Cancer 41: 456-461.
-
(1988)
Int. J. Cancer
, vol.41
, pp. 456-461
-
-
Hwl, Z.-H.1
Thiel, E.2
Fütterer, A.3
Herzog, V.4
Wirtz, A.5
Riethmüller, G.6
-
27
-
-
0016319012
-
Estimation of linkage disequilibrium in randomly mating populations
-
Hill WG. (1974) Estimation of linkage disequilibrium in randomly mating populations. Heredity 33: 229-239.
-
(1974)
Heredity
, vol.33
, pp. 229-239
-
-
Hill, W.G.1
-
28
-
-
0029759382
-
Population haplotype analysis and evolutionary relations of the COL2A1
-
Meulenbelt I, Williams CJ, Te Koppele JM, Van de Giessen GC, Slagboom PE. ( 1996) Population haplotype analysis and evolutionary relations of the COL2A1. Ann. Hum. Genet. 60: 189-199.
-
(1996)
Ann. Hum. Genet.
, vol.60
, pp. 189-199
-
-
Meulenbelt, I.1
Williams, C.J.2
Te Koppele, J.M.3
Van De Giessen, G.C.4
Slagboom, P.E.5
-
29
-
-
0028979244
-
Genetic variability in the TNF-a promoter is not associated with type II diabetes mellitus (NIDDM)
-
Hamann A, Mantzoros C, Vidal-Puig A, Flier JS. (1995) Genetic variability in the TNF-a promoter is not associated with type II diabetes mellitus (NIDDM). Biochem. Biophys. Res. Commun. 211: 833-839.
-
(1995)
Biochem. Biophys. Res. Commun.
, vol.211
, pp. 833-839
-
-
Hamann, A.1
Mantzoros, C.2
Vidal-Puig, A.3
Flier, J.S.4
-
30
-
-
0029928977
-
Association between polymorphisms in the TNF region and systemic lupus erythematosus in the Italian population
-
D'Alfonso S, Colombo G, Delia Bella S, Scorza R, Momigliano-Richiardi P. (1996) Association between polymorphisms in the TNF region and systemic lupus erythematosus in the Italian population. Tissue Antigens 47: 551-555.
-
(1996)
Tissue Antigens
, vol.47
, pp. 551-555
-
-
D'Alfonso, S.1
Colombo, G.2
Delia Bella, S.3
Scorza, R.4
Momigliano-Richiardi, P.5
-
31
-
-
0028318464
-
Identification and characterization of a novel repressor site in the human tumor necrosis factor a gene
-
Fong C-LW, Siddiqui AH, Mark DF. (1994) Identification and characterization of a novel repressor site in the human tumor necrosis factor a gene. Nucl. Add Res. 22: 1108-1114.
-
(1994)
Nucl. Add Res.
, vol.22
, pp. 1108-1114
-
-
Fong, C.-L.W.1
Siddiqui, A.H.2
Mark, D.F.3
-
32
-
-
0032516519
-
Complex NF-kappaB interactions at the distal tumor necrosis factor promoter region in human monocytes
-
Udalova IA, Knight JC, Vidai V, Nedospasov SA, Kwiatkowski D. (1998) Complex NF-kappaB interactions at the distal tumor necrosis factor promoter region in human monocytes. J. Biol. Chem. 273: 21178-21186.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 21178-21186
-
-
Udalova, I.A.1
Knight, J.C.2
Vidai, V.3
Nedospasov, S.A.4
Kwiatkowski, D.5
-
33
-
-
0024202995
-
Association between HLA-DR2 and production of tumour necrosis factor a and Interleukin 1 by mononuclear cells activated by lipopolysaccharide
-
Bendtzen K, Morling N, Fomsgaard A, et al. (1988) Association between HLA-DR2 and production of tumour necrosis factor a and Interleukin 1 by mononuclear cells activated by lipopolysaccharide. Scand. J. Immunol. 28: 599-606.
-
(1988)
Scand. J. Immunol.
, vol.28
, pp. 599-606
-
-
Bendtzen, K.1
Morling, N.2
Fomsgaard, A.3
-
34
-
-
0025016823
-
Heritable major hislocompatibility complex class II-associated differences in production of tumor necrosis factor a: Relevance to genetic predisposition to systemic lupus erythemaiosus
-
Jacob CO, Fronek Z, Lewis GD, Koo M, Hansen JA, McDcvitt HO. (1990) Heritable major hislocompatibility complex class II-associated differences in production of tumor necrosis factor a: relevance to genetic predisposition to systemic lupus erythemaiosus. Proc. Natl. Acad. Sci. U.S.A. 87: 1233-1237.
-
(1990)
Proc. Natl. Acad. Sci. U.S.A.
, vol.87
, pp. 1233-1237
-
-
Jacob, C.O.1
Fronek, Z.2
Lewis, G.D.3
Koo, M.4
Hansen, J.A.5
McDcvitt, H.O.6
-
35
-
-
0023041566
-
Tumour necrosis factor as immunomodulator and mediator of monocyte cytoloxicity induced by itself, γ-interferon and interleukin-1
-
Philip R, Epstein LB. (1986) Tumour necrosis factor as immunomodulator and mediator of monocyte cytoloxicity induced by itself, γ-interferon and interleukin-1. Nature 323: 86-89.
-
(1986)
Nature
, vol.323
, pp. 86-89
-
-
Philip, R.1
Epstein, L.B.2
-
36
-
-
0028805395
-
Functional analysis of a new polymorphism in the human TNF α gene promoter
-
Pociot F, D'Alfonso S, Compasso S, Scorza R, and Richiardi PM. ( 1995) Functional analysis of a new polymorphism in the human TNF α gene promoter. Scand. J. Immunol. 42: 501-504.
-
(1995)
Scand. J. Immunol.
, vol.42
, pp. 501-504
-
-
Pociot, F.1
D'Alfonso, S.2
Compasso, S.3
Scorza, R.4
Richiardi, P.M.5
-
37
-
-
0027534914
-
An allelic polymorphism within the human tumor necrosis factor a promoter region is strongly associated with HLA Al, B8, and DR3 alleles
-
Wilson AG, de Vries N, Pociot F, Di Giovine FS, van der Putte LBA, Duff GW. (1993) An allelic polymorphism within the human tumor necrosis factor a promoter region is strongly associated with HLA Al, B8, and DR3 alleles. J. Exp. Med. 177: 557-560.
-
(1993)
J. Exp. Med.
, vol.177
, pp. 557-560
-
-
Wilson, A.G.1
De Vries, N.2
Pociot, F.3
Di Giovine, F.S.4
Van Der Putte, L.B.A.5
Duff, G.W.6
-
38
-
-
0028169333
-
Variation in the TNF-a promoter region associated with susceptibility to cerebral malaria
-
McGuire W, Hill AVS, Allsopp CEM, Greenwood BM, Kwiatkowski D. (1994) Variation in the TNF-a promoter region associated with susceptibility to cerebral malaria. Nature 371: 508-511.
-
(1994)
Nature
, vol.371
, pp. 508-511
-
-
McGuire, W.1
Avs, H.2
Cem, A.3
Greenwood, B.M.4
Kwiatkowski, D.5
-
39
-
-
0028832278
-
Polymorphism in tumor necrosis factor genes associated with mucocutaneous leishmaniasis
-
Cabrera M, Shaw MA, Sharpies C, et al. (1995) Polymorphism in tumor necrosis factor genes associated with mucocutaneous leishmaniasis. J. Exp. Med. 182: 1259-1264.
-
(1995)
J. Exp. Med.
, vol.182
, pp. 1259-1264
-
-
Cabrera, M.1
Ma, S.2
Sharpies, C.3
-
40
-
-
0030954180
-
Effects of a polymorphism in the human tumor necrosis factor a promoter on transcriptional activation
-
Wilson AG, Symons JA, McDowell TL, McDevitt HO, Duff GW. (1997) Effects of a polymorphism in the human tumor necrosis factor a promoter on transcriptional activation. Proc. Natl. Acad. Sci. U.S.A. 94: 3195-3199.
-
(1997)
Proc. Natl. Acad. Sci. U.S.A.
, vol.94
, pp. 3195-3199
-
-
Wilson, A.G.1
Symons, J.A.2
McDowell, T.L.3
McDevitt, H.O.4
Duff, G.W.5
-
41
-
-
0030862033
-
The -308 tumor necrosis factor-α promoter polymorphism effects transcription
-
Kroeger KM, Carville KS, Abraham LJ. ( 1997) The -308 tumor necrosis factor-α promoter polymorphism effects transcription. Mol. Immunol. 34: 391-399.
-
(1997)
Mol. Immunol.
, vol.34
, pp. 391-399
-
-
Kroeger, K.M.1
Carville, K.S.2
Abraham, L.J.3
-
42
-
-
0029880580
-
-308 Tumor necrosis factor (TNF) polymorphism is not associated with survival in severe sepsis and is unrelated to lipopolysaccharide inducibility of the human TNF promoter
-
Stüber F, Udalova IA, Book M, et al. (1996) -308 Tumor necrosis factor (TNF) polymorphism is not associated with survival in severe sepsis and is unrelated to lipopolysaccharide inducibility of the human TNF promoter. J. Inflam. 46: 42-50.
-
(1996)
J. Inflam.
, vol.46
, pp. 42-50
-
-
Stüber, F.1
Udalova, I.A.2
Book, M.3
-
43
-
-
0029097750
-
Localization of the human stress responsive MAP kinase-like CSAIDs binding protein (CSBP) gene to chromosome 6p21.3/21.1
-
McDonnell PC, DiLella AG, Lee JC, Young PR. (1995) Localization of the human stress responsive MAP kinase-like CSAIDs binding protein (CSBP) gene to chromosome 6p21.3/21.1. Genomics 28: 301-302.
-
(1995)
Genomics
, vol.28
, pp. 301-302
-
-
McDonnell, P.C.1
Dilella, A.G.2
Lee, J.C.3
Young, P.R.4
-
44
-
-
0028274641
-
Characterization of a novel gene in the human major histocompatibility complex of the i kappa B family of proteins
-
Albertella MR, Campbell RD. (1994) Characterization of a novel gene in the human major histocompatibility complex of the I kappa B family of proteins. Hum. Mol. Genet. 3: 793-799.
-
(1994)
Hum. Mol. Genet.
, vol.3
, pp. 793-799
-
-
Albertella, M.R.1
Campbell, R.D.2
-
45
-
-
0027415883
-
The G9a gene in the human major histocompatibility complex encodes a novel protein containing ankyrin-like repeats
-
MilnerCM, Campbell RD. (1993) The G9a gene in the human major histocompatibility complex encodes a novel protein containing ankyrin-like repeats. Biochem. J. 290: 811-818.
-
(1993)
Biochem. J.
, vol.290
, pp. 811-818
-
-
Milner, C.M.1
Campbell, R.D.2
|