메뉴 건너뛰기




Volumn 52, Issue 2, 2003, Pages 109-118

Applications of recombinant Leishmania amazonensis expressing egfp or the β-galactosidase gene for drug screening and histopathological analysis

Author keywords

galactosidase; Drug screening; Enhanced green fluorescent protein; Histopathological analysis; Recombinant Leishmania amazonensis

Indexed keywords

5 BROMO 4 CHLORO 3 INDOLYL BETA GALACTOPYRANOSIDE; AMPHOTERICIN B; BETA GALACTOPYRANOSIDE; BETA GALACTOSIDASE; CHLOROPHENOL; DYE; ENHANCED GREEN FLUORESCENT PROTEIN; PLASMID VECTOR; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG; ANTIPROTOZOAL AGENT;

EID: 0037780215     PISSN: 13411357     EISSN: None     Source Type: Journal    
DOI: 10.1538/expanim.52.109     Document Type: Article
Times cited : (40)

References (25)
  • 2
    • 0031689546 scopus 로고    scopus 로고
    • Mixed infection of human U-973 cells by two different species of Leishmania
    • Abdullah, S.M., Flath, B., and Presber, W. 1998. Mixed infection of human U-973 cells by two different species of Leishmania. Am. J. Trop. Med Hyg. 59: 182-188.
    • (1998) Am. J. Trop. Med. Hyg. , vol.59 , pp. 182-188
    • Abdullah, S.M.1    Flath, B.2    Presber, W.3
  • 3
    • 0029917084 scopus 로고    scopus 로고
    • Biological behavior of Leishmania amazonensis isolated from human with cutaneous, mucosal, or visceral leishmaniasis in BALB/c mice
    • Almeid, R.P., Barral N.M., Jesus, A.M.R., Frietas, L.A.R., Carvalho, E.M., and Barral, A. 1996. Biological behavior of Leishmania amazonensis isolated from human with cutaneous, mucosal, or visceral leishmaniasis in BALB/c mice. Am. J. Trop. Med. Hyg. 54: 178-184.
    • (1996) Am. J. Trop. Med. Hyg. , vol.54 , pp. 178-184
    • Almeid, R.P.1    Barral, N.M.2    Jesus, A.M.R.3    Frietas, L.A.R.4    Carvalho, E.M.5    Barral, A.6
  • 6
    • 0025923638 scopus 로고
    • Leishmania amazonensis is implicated in the whole spectrum of human clinical leishmaniasis
    • Barral, A. 1991. Leishmania amazonensis is implicated in the whole spectrum of human clinical leishmaniasis. Am. J. Trop. Med. Hyg. 44: 536-546.
    • (1991) Am. J. Trop. Med. Hyg. , vol.44 , pp. 536-546
    • Barral, A.1
  • 7
    • 0021145297 scopus 로고
    • Activity of antileishmanial agents against amastigotes in human monocyte-derived macrophages and in mouse peritoneal macrophages
    • Berman, J.D. and Lee, L.S. 1984. Activity of antileishmanial agents against amastigotes in human monocyte-derived macrophages and in mouse peritoneal macrophages. J Parasit. 70: 220-225.
    • (1984) J. Parasit. , vol.70 , pp. 220-225
    • Berman, J.D.1    Lee, L.S.2
  • 8
    • 0018891082 scopus 로고
    • Influence of H-2 complex on acquired resistance to Leishmania donovani infection in mice
    • Blackwell, J., Freeman, J., and Bradley, D. 1980. Influence of H-2 complex on acquired resistance to Leishmania donovani infection in mice. Nature. 283: 72-74.
    • (1980) Nature , vol.283 , pp. 72-74
    • Blackwell, J.1    Freeman, J.2    Bradley, D.3
  • 9
    • 0028822932 scopus 로고
    • New mechanism of drug resistance in parasitic protozoa
    • Borst, P. and Ouellette, M. 1995. New mechanism of drug resistance in parasitic protozoa. Annu. Rev. Microbiol. 49: 427-460.
    • (1995) Annu. Rev. Microbiol. , vol.49 , pp. 427-460
    • Borst, P.1    Ouellette, M.2
  • 10
    • 0029957682 scopus 로고    scopus 로고
    • Carrier effects on biological activity of Amphotericin B
    • Brajtburg, J. and Bolard, J. 1996. Carrier effects on biological activity of Amphotericin B. Clin. Microbiol. Rev. 9: 512-531.
    • (1996) Clin. Microbiol. Rev. , vol.9 , pp. 512-531
    • Brajtburg, J.1    Bolard, J.2
  • 11
    • 0032892735 scopus 로고    scopus 로고
    • Detection of live Trypanosoma cruzi in tissues of infected mice by using histochemical stain for β-galactosidase
    • Buckner, F.S., Wilson, A.J., and Voorhis, W.C. 1999. Detection of live Trypanosoma cruzi in tissues of infected mice by using histochemical stain for β-galactosidase. Am. Soc. microbiol. 403-409.
    • (1999) Am. Soc. Microbiol. , pp. 403-409
    • Buckner, F.S.1    Wilson, A.J.2    Voorhis, W.C.3
  • 12
    • 0023864576 scopus 로고
    • DNA amplification in tunicamycin-resistant Leishmania Mexicana. Multicopies of a single 63-kilobase supercoiled molecule and their expression
    • Detke, S., Chaudhuri, G., Kink, J.A., and Chang. K.P. 1988. DNA amplification in tunicamycin-resistant Leishmania Mexicana. Multicopies of a single 63-kilobase supercoiled molecule and their expression. J. Biol. Chem. 263: 3418-3424.
    • (1988) J. Biol. Chem. , vol.263 , pp. 3418-3424
    • Detke, S.1    Chaudhuri, G.2    Kink, J.A.3    Chang, K.P.4
  • 13
    • 0033966027 scopus 로고    scopus 로고
    • Episomal expression of specific sense and antisense mRNAs in Leishmania amazonensis: Modulation of gp63 level in promastigotes and their infection of macrophages in vitro
    • Chen, D.Q., Kolli, B.K., Yadaba, N., Lu, H.G., Gilman-Sachs, A., Peterson, D.A., and Chang, K.P. 2000. Episomal expression of specific sense and antisense mRNAs in Leishmania amazonensis: modulation of gp63 level in promastigotes and their infection of macrophages in vitro. Infect. Immun. 68: 80-86.
    • (2000) Infect. Immun. , vol.68 , pp. 80-86
    • Chen, D.Q.1    Kolli, B.K.2    Yadaba, N.3    Lu, H.G.4    Gilman-Sachs, A.5    Peterson, D.A.6    Chang, K.P.7
  • 14
    • 0019119560 scopus 로고
    • Trypanosoma rhodesiense: Semiautomated microtesting for quantitation of antitrypanosomal activity in vitro
    • Desjardins, R.E., Casero, R.A.Jr., Willet, G.P., Childs, G.E., and Canfield, C.J. 1980. Trypanosoma rhodesiense: Semiautomated microtesting for quantitation of antitrypanosomal activity in vitro. Exp. Parasitol 50: 260-271.
    • (1980) Exp. Parasitol. , vol.50 , pp. 260-271
    • Desjardins, R.E.1    Casero Jr., R.A.2    Willet, G.P.3    Childs, G.E.4    Canfield, C.J.5
  • 15
    • 0027429249 scopus 로고
    • A colorimetric assay for trypanosome viability and metabolic function
    • Ellis, J.A., Fish, W.R., Sileghem, M., and McOdimba, F. 1993. A colorimetric assay for trypanosome viability and metabolic function. Vet. Parasitol. 50: 143-149.
    • (1993) Vet. Parasitol. , vol.50 , pp. 143-149
    • Ellis, J.A.1    Fish, W.R.2    Sileghem, M.3    McOdimba, F.4
  • 16
    • 0024853396 scopus 로고
    • A review of the geographic distribution and epidemiology of leishmaniasis in the New World
    • Grimerdi, Jr.G., Tesh, R.B., and McMahon, P.D. 1989. A review of the geographic distribution and epidemiology of leishmaniasis in the New World. Am. J. Trop. Med. Hyg. 41: 687-725.
    • (1989) Am. J. Trop. Med. Hyg. , vol.41 , pp. 687-725
    • Grimerdi Jr., G.1    Tesh, R.B.2    McMahon, P.D.3
  • 18
    • 0026769377 scopus 로고
    • Drug resistance in Leishmaniasis: Its implication in systemic chemotherapy of cutaneous and mucocutaneous disease
    • Max, G. Tina, N.T., and Eileen, D.F. 1992. Drug resistance in Leishmaniasis: Its implication in systemic chemotherapy of cutaneous and mucocutaneous disease. Am. J. Trop. Med. Hyg. 47: 117-126.
    • (1992) Am. J. Trop. Med. Hyg. , vol.47 , pp. 117-126
    • Max, G.1    Tina, N.T.2    Eileen, D.F.3
  • 19
    • 0030826746 scopus 로고    scopus 로고
    • Use of Toxoplasma gondii expressing β-Galactosidase for colorimetric assessment of drug activity in vitro
    • McFadden, D., Seeber, F., and Boothroid, J.C. 1997. Use of Toxoplasma gondii expressing β-Galactosidase for colorimetric assessment of drug activity in vitro. Antimicrob Agents and Chemother. 1849-1853.
    • (1997) Antimicrob. Agents and Chemother. , pp. 1849-1853
    • McFadden, D.1    Seeber, F.2    Boothroid, J.C.3
  • 20
    • 0242693036 scopus 로고    scopus 로고
    • Targeted integration into a rRNA locus results in uniform and high level expression of transgenes in Leishmania amastigotes
    • Miblitz, A., Motram, J.C., Overath, P., and Abischer. T. 2000. Targeted integration into a rRNA locus results in uniform and high level expression of transgenes in Leishmania amastigotes. Mol. Biochem. Parasitol. 107: 251-261.
    • (2000) Mol. Biochem. Parasitol. , vol.107 , pp. 251-261
    • Miblitz, A.1    Motram, J.C.2    Overath, P.3    Abischer, T.4
  • 21
    • 0033991437 scopus 로고    scopus 로고
    • A simple colorimetric method to screen drug cytotoxicity against Leishmania using the dye Alamer Blue
    • Mikus, J. and Steverding, D. 2000. A simple colorimetric method to screen drug cytotoxicity against Leishmania using the dye Alamer Blue. Parasitol Inter. 48: 265-269.
    • (2000) Parasitol. Inter. , vol.48 , pp. 265-269
    • Mikus, J.1    Steverding, D.2
  • 22
    • 0028951792 scopus 로고
    • A novel in vitro screening assay for trypanocidal activity using the fluorescent dye BCECF-AM
    • Obexer, W., Schmid, G., and Brun R. 1995. A novel in vitro screening assay for trypanocidal activity using the fluorescent dye BCECF-AM. Trop. Med. Parasitol. 46: 45-48.
    • (1995) Trop. Med. Parasitol. , vol.46 , pp. 45-48
    • Obexer, W.1    Schmid, G.2    Brun, R.3
  • 23
    • 0030990411 scopus 로고    scopus 로고
    • Use of an enzymatic micromethod to quantify amastigote stage of Leishmania amazonensis in vitro
    • Sereno, D. and Lemesre, J.L,. 1997. Use of an enzymatic micromethod to quantify amastigote stage of Leishmania amazonensis in vitro. Parasitol. Res. 83: 401-403.
    • (1997) Parasitol. Res. , vol.83 , pp. 401-403
    • Sereno, D.1    Lemesre, J.L.2
  • 24
    • 0023734112 scopus 로고
    • Recent developments in the chemotherapy of leishmaniasis
    • Simon, L.C. 1988. Recent developments in the chemotherapy of leishmaniasis. TIPS-October 9: 376-381.
    • (1988) TIPS-October , vol.9 , pp. 376-381
    • Simon, L.C.1
  • 25
    • 0030003134 scopus 로고    scopus 로고
    • Applications for green fluorescent protein (GFP) in the study of host-pathogen interactions
    • Valdivia, R.H.. Hromockyj, A.E., Monack, D., Ramakrishnan, L., and Falkow, S. 1996. Applications for green fluorescent protein (GFP) in the study of host-pathogen interactions. Gene. 173: 47-52.
    • (1996) Gene , vol.173 , pp. 47-52
    • Valdivia, R.H.1    Hromockyj, A.E.2    Monack, D.3    Ramakrishnan, L.4    Falkow, S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.