Functional characterization of three human cytochrome P450 2E1 variants with amino acid substitutions

Xenobiotica

Volumn 33, Issue 6, 2003, Pages 575-586

  Hanioka, N ^a   Tanaka Kagawa, T ^a   Miyata, Y ^b   Matsushima, E ^a   Makino, Y ^a   Ohno, A ^a   Yoda, R ^b   Jinno, H ^a   Ando, M ^a  

^a NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

^b KEIO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

4 NITROPHENOL; AMINO ACID; ARGININE; CHLORZOXAZONE; CYTOCHROME P450 2E1; CYTOCHROME P450 2E1.1; CYTOCHROME P450 2E1.2; CYTOCHROME P450 2E1.3; DRUG; ENVIRONMENTAL CHEMICAL; ENZYME VARIANT; HISTIDINE; ISOLEUCINE; LIVER ENZYME; UNCLASSIFIED DRUG; VALINE; XENOBIOTIC AGENT;

AEROBIC METABOLISM; AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CAUCASIAN; CELL STRAIN COS1; CHINESE; CONTROLLED STUDY; CYP2E1 GENE; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME KINETICS; GENE; GENETIC POLYMORPHISM; HYDROXYLATION; NONHUMAN; PROTEIN CONTENT; STRUCTURE ACTIVITY RELATION; XENOBIOTIC METABOLISM;

AMINO ACID SUBSTITUTION; ANIMALS; CHLORZOXAZONE; COS CELLS; CYTOCHROME P-450 CYP2E1; DNA PRIMERS; DNA, COMPLEMENTARY; HUMANS; KINETICS; NITROPHENOLS; PLASMIDS; RNA, MESSENGER;

ANIMALIA;

EID: 0037757990     PISSN: 00498254     EISSN: None     Source Type: Journal    
DOI: 10.1080/0049825031000086400     Document Type: Article

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