Catechol-O-methyltransferase gene polymorphism and post-menopausal breast cancer risk

Carcinogenesis

Volumn 24, Issue 4, 2003, Pages 681-687

  Wedrén, Sara ^a   Rudqvist, Tove Rylander ^a   Granath, Fredrik ^a   Weiderpass, Elisabete ^a,b   Ingelman Sundberg, Magnus ^a   Persson, Ingemar ^a,c   Magnusson, Cecilia ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b INTERNATIONAL AGENCY FOR RESEARCH ON CANCER   (France)

^c MEDICAL PRODUCTS AGENCY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

CATECHOL METHYLTRANSFERASE; ESTROGEN; METHIONINE; VALINE;

ADULT; AGED; ARTICLE; BREAST CANCER; BREAST CARCINOGENESIS; CANCER INVASION; CANCER RISK; CASE CONTROL STUDY; CONFIDENCE INTERVAL; CONTROLLED STUDY; DIABETES MELLITUS; DNA POLYMORPHISM; ENZYME ACTIVITY; FEMALE; GENE FUNCTION; GENETIC ASSOCIATION; GENOTYPE; HIGH RISK POPULATION; HISTOPATHOLOGY; HUMAN; HYPOTHESIS; LOGISTIC REGRESSION ANALYSIS; MAJOR CLINICAL STUDY; NULLIPARA; POSTMENOPAUSE; PRIORITY JOURNAL; STATISTICAL SIGNIFICANCE; SWEDEN;

AGED; BREAST NEOPLASMS; CASE-CONTROL STUDIES; CATECHOL O-METHYLTRANSFERASE; HUMANS; MIDDLE AGED; POLYMORPHISM, GENETIC; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; POSTMENOPAUSE; RISK FACTORS;

EID: 0037717169     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/bgg022     Document Type: Article

References (34)

1. Yager,J.D. and Liehr,J.G. (1996) Molecular mechanisms of estrogen carcinogenesis. Annu. Rev. Pharmacol. Toxicol., 36, 203-232.
2. Lachman,H.M., Papolos,D.F., Saito,T., Yu,Y.M., Szumlanski,C.L. and Weinshilboum,R.M. (1996) Human catechol-O-methyltransferase pharmacogenetics: description of a functional polymorphism and its potential application to neuropsychiatric disorders. Pharmacogenetics, 6, 243-250.
3. Dawling,S., Roodi,N., Mernaugh,R.L., Wang,X. and Parl,F.F. (2001) Catechol-O-methyltransferase (COMT)-mediated metabolism of catechol estrogens: comparison of wild-type and variant COMT isoforms. Cancer Res., 61, 6716-6722.
4. Syvanen,A.C., Tilgmann,C., Rinne,J. and Ulmanen,I. (1997) Genetic polymorphism of catechol-O-methyltransferase (COMT): correlation of genotype with individual variation of S-COMT activity and comparison of the allele frequencies in the normal population and parkinsonian patients in Finland. Pharmacogenetics, 7, 65-71.
5. Lavigne,J.A., Goodman,J.E., Fonong,T., Odwin,S., He,P., Roberts,D.W. and Yager,J.D. (2001) The effects of catechol-O-methyltransferase inhibition on estrogen metabolite and oxidative DNA damage levels in estradiol-treated MCF-7 cells. Cancer Res., 61, 7488-7494.
6. Magnusson,C.M., Persson,I.R., Baron,J.A., Ekbom,A., Bergstrom,R. and Adami,H.O. (1999) The role of reproductive factors and use of oral contraceptives in the aetiology of breast cancer in women aged 50 to 74 years. Int. J. Cancer, 80, 231-236.
7. Magnusson,C., Colditz,G., Rosner,B., Bergstrom,R. and Persson,I. (1998) Association of family history and other risk factors with breast cancer risk (Sweden). Cancer Causes Control, 9, 259-267.
8. Magnusson,C., Baron,J.A., Correia,N., Bergstrom,R., Adami,H.O. and Persson,J. (1999) Breast-cancer risk following long-term oestrogen- and oestrogen-progestin-replacement therapy. Int. J. Cancer, 81, 339-344.
9. Terry,P., Wolk,A., Persson,I. and Magnusson,C. (2001) Brassica vegetables and breast cancer risk. J. Am. Med. Assoc., 285, 2975-2977.
10. Moradi,T., Nyren,O., Zack,M., Magnusson,C., Persson,I. and Adami,H.O. (2000) Breast cancer risk and lifetime leisure-time and occupational physical activity (Sweden). Cancer Causes Control, 11, 523-531.
11. Isola,J., DeVries,S., Chu,L., Ghazvini,S. and Waldman,F. (1994) Analysis of changes in DNA sequence copy number by comparative genomic hybridization in archival paraffin-embedded tumor samples. Am. J. Pathol., 145, 1301-1308.
12. Pastinen,T., Partanen,J. and Syvanen,A.C. (1996) Multiplex, fluorescent, solid-phase minisequencing for efficient screening of DNA sequence variation. Clin. Chem., 42, 1391-1397.
13. Prince,J.A., Feuk,L., Howell,W.M., Jobs,M., Emahazion,T., Blennow,K. and Brookes,A.J. (2001) Robust and accurate single nucleotide polymorphism genotyping by dynamic allele-specific hybridization (DASH): design criteria and assay validation. Genome Res., 11, 152-162.
14. Howell,W.M., Jobs,M., Gyllensten,U. and Brookes,A.J. (1999) Dynamic allele-specific hybridization. A new method for scoring single nucleotide polymorphisms. Nature Biotechnol., 17, 87-88.
15. Spielman,R.S. and Weinshilboum,R.M. (1981) Genetics of red cell COMT activity: analysis of thermal stability and family data. Am. J. Med. Genet., 10, 279-290.
16. Chen,C.L., Weiss,N.S., Newcomb,P., Barlow,W. and White,E. (2002) Hormone replacement therapy in relation to breast cancer. J. Am. Med. Assoc., 287, 734-741.
17. Newcomb,P.A., Titus-Ernstoff,L., Egan,K.M., Trentham-Dietz,A., Baron,J.A., Storer,B.E., Willett,W.C. and Stampfer,M.J. (2002) Postmenopausal estrogen and progestin use in relation to breast cancer risk. Cancer Epidemiol. Biomarkers Prev., 11, 593-600.
18. Kaaks,R. and Lukanova,A. (2001) Energy balance and cancer: the role of insulin and insulin-like growth factor-I. Proc. Nutr. Soc., 60, 91-106.
19. Wang,J.P., Liu,I.M., Tzeng,T.F. and Cheng,J.T. (2002) Decrease in catechol-O-methyltransferase activity in the liver of streptozotocin-induced diabetic rats. Clin. Exp. Pharmacol. Physiol., 29, 419-422.
20. Park,T.W., Yoon,K.S., Kim,J.H., Park,W.Y., Hirvonen,A. and Kang,D. (2002) Functional catechol-O-methyltransferase gene polymorphism and susceptibility to schizophrenia. Eur. Neuropsychopharmacol., 12, 299-303.
21. Malhotra,A.K., Kestler,L.J., Mazzanti,C., Bates,J.A., Goldberg,T. and Goldman,D. (2002) A functional polymorphism in the COMT gene and performance on a test of prefrontal cognition. Am. J. Psychiatry, 159, 652-654.
22. Thompson,P.A. and Ambrosone,C. (2000) Molecular epidemiology of genetic polymorphisms in estrogen metabolizing enzymes in human breast cancer. J. Natl Cancer Inst. Monogr., 125-134.
23. Haiman,C.A., Bernstein,L., Berg,D., Ingles,S.A., Salane,M. and Ursin,G. (2002) Genetic determinants of mammographic density. Breast Cancer Res., 4, R5.
24. Lavigne,J.A., Helzlsouer,K.J., Huang,H.Y., Strickland,P.T., Bell,D.A., Selmin,O., Watson,M.A., Hoffman,S., Comstock,G.W. and Yager,J.D. (1997) An association between the allele coding for a low activity variant of catechol-O-methyltransferase and the risk for breast cancer. Cancer Res., 57, 5493-5497.
25. Thompson,P.A., Shields,P.G., Freudenheim,J.L. et al. (1998) Genetic polymorphisms in catechol-O-methyltransferase, menopausal status and breast cancer risk. Cancer Res., 58, 2107-2110.
26. Millikan,R.C., Pittman,G.S., Tse,C.K., Duell,E., Newman,B., Savitz,D., Moorman,P.G., Boissy,R.J. and Bell,D.A. (1998) Catechol-O-methyltransferase and breast cancer risk. Carcinogenesis, 19, 1943-1947.
27. Mitrunen,K., Jourenkova,N., Kataja,V., Eskelinen,M., Kosma,V.M., Benhamou,S., Kang,D., Vainio,H., Uusitupa,M. and Hirvonen,A. (2001) Polymorphic catechol-O-methyltransferase gene and breast cancer risk. Cancer Epidemiol. Biomarkers Prev., 10, 635-640.
28. Hamajima,N., Matsuo,K., Tajima,K., Mizutani,M., Iwata,H., Iwase,T., Miura,S., Oya,H. and Obata,Y. (2001) Limited association between a catechol-O-methyltransferase (COMT) polymorphism and breast cancer risk in Japan. Int. J. Clin. Oncol., 6, 13-18.
29. Yim,D.S., Park,S.K., Yoo,K.Y. et al. (2001) Relationship between the Val158Met polymorphism of catechol O-methyl transferase and breast cancer. Pharmacogenetics, 11, 279-286.
30. Goodman,J.E., Lavigne,J.A., Wu,K., Helzlsouer,K.J., Strickland,P.T., Selhub,J. and Yager,J.D. (2001) COMT genotype, micronutrients in the folate metabolic pathway and breast cancer risk. Carcinogenesis, 22, 1661-1665.
31. Mitrunen,K., Kataja,V., Eskelinen,M., Kosma,V.M., Kang,D., Benhamou,S., Vainio,H., Uusitupa,M. and Hirvonen,A. (2002) Combined COMT and GST genotypes and hormone replacement therapy associated breast cancer risk. Pharmacogenetics, 12, 67-72.
32. Matsui,A., Ikeda,T., Enomoto,K., Nakashima,H., Omae,K., Watanabe,M., Hibi,T. and Kitajima,M. (2000) Progression of human breast cancers to the metastatic state is linked to genotypes of catechol-O-methyltransferase. Cancer Lett., 150, 23-31.
33. Huang,C.S., Chern,H.D., Chang,K.J., Cheng,C.W., Hsu,S.M. and Shen,C.Y. (1999) Breast cancer risk associated with genotype polymorphism of the estrogen-metabolizing genes CYP17, CYP1A1 and COMT: a multigenic study on cancer susceptibility. Cancer Res., 59, 4870-4875.
34. Bergman-Jungestrom,M. and Wingren,S. (2001) Catechol-O-methyltransferase. (COMT) gene polymorphism and breast cancer risk in young women. Br. J. Cancer, 85, 859-862.