Genetic polymorphisms in catechol-O-methyltransferase, menopausal status, and breast cancer risk

Cancer Research

Volumn 58, Issue 10, 1998, Pages 2107-2110

  Thompson, Patricia A ^a   Shields, Peter G ^b   Freudenheim, Jo L ^c   Stone, Angie ^a   Vena, John E ^c   Marshall, James R ^d   Graham, Saxon ^c   Laughlin, Rosemary ^c   Nemoto, Takuma ^c   Kadlubar, Fred F ^a   Ambrosone, Christine B ^a  

^a NATIONAL CENTER FOR TOXICOLOGICAL RESEARCH   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

^c UNIVERSITY AT BUFFALO   (United States)

^d UNIVERSITY OF ARIZONA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATECHOL METHYLTRANSFERASE;

ADULT; AGED; ARTICLE; BREAST CANCER; CANCER GENETICS; CANCER RISK; CONTROLLED STUDY; FEMALE; GENETIC POLYMORPHISM; GENETIC RISK; HUMAN; MAJOR CLINICAL STUDY; MENOPAUSE; POSTMENOPAUSE; PREMENOPAUSE; PRIORITY JOURNAL;

BODY MASS INDEX; BREAST NEOPLASMS; CASE-CONTROL STUDIES; CATECHOL O-METHYLTRANSFERASE; FEMALE; HUMANS; MENOPAUSE; MIDDLE AGED; NEOPLASM PROTEINS; POLYMORPHISM, GENETIC; POSTMENOPAUSE; PREMENOPAUSE; RISK ASSESSMENT;

EID: 14444276295     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (32)

1. Adlercreutz, H., Gorbach, S. L., Goldin, B. R., Woods, M. N., Dwyer, J. T., and Hamalainen, E. Estrogen metabolism and excretion in Oriental and Caucasian women. J. Natl. Cancer Inst., 86: 1076-1082, 1994.
2. Lemon, H. M., Heidel, J. W., and Rodriquez-Sierra, J. F. Increased catechol estrogen metabolism as a risk factor for nonfamilial breast cancer. Cancer (Phila.), 69: 457-465, 1992.
3. Bradlow, H. L., Telang, N. T., Sepkovic, D. W., and Osborne, M. P. 2-Hydroxy estrone: the "good" estrogen. J. Endocrinol., 150: S259-S265, 1996.
4. Martucci, C. P., and Fishman, J. P 450 enzymes of estrogen metabolism. Pharmacol. Ther., 57: 237-257, 1993.
5. MacLusky, J. J., Barnea, E. R., Clark, C. R., and Naftolin, F. Catechol estrogens and estrogen receptors. In: G. R. Merriam and M. B. Lipsett (eds.), Catechol Estrogens, pp. 151-165. New York: Raven Press, 1983.
6. Yager, J. D., and Liehr, J. G. Molecular mechanisms of estrogen carcinogenesis. Annu. Rev. Pharmacol. Toxicol., 36: 203-232, 1996.
7. Cavalieri, E. L., Stack, D. E., Devanesan, P. D., Todorovic, R., Dwivedy, I., Higginbotham, S., Johansson, S. L., Patil, K. D., Gross, M. L., Gooden, J. K., Ramanathan, R., Cerny, R. L., and Rogan, E. G. Molecular origin of cancer-catechol estrogen-3,4-quinones as endogenous tumor initiators. Proc. Natl. Acad, Sci. USA, 94: 10937-10942, 1997.
8. Fishman, J. Biological action of catechol estrogens. J. Endocrinol., 85: 59P-65P, 1981.
9. Liehr, J. G. Genotoxic effects of estrogens. Mutat. Res., 238: 269-276, 1990.
10. Conney, A. H., Levin, W., Jacobson, M., and Kuntzman, R. Effects of drugs and environmental chemicals on steroid metabolism. Clin. Pharmacol. Ther., 14: 727-741, 1973.
11. Guengerich, F. P. Human cytochrome P450 enzymes. In: Ortiz de P. R. Montellano (ed.), Cytochrome P450: Structure, Mechanism, and Biochemistry, Ed. 2, pp. 473-535. New York: Plenum Publishing Corp., 1995.
12. Feigelson, H. S., Ross, R. K., Yu, M. C., Coetzee, G. A., Reichardt, J. K., and Henderson, B. E. Genetic susceptibility to cancer from exogenous and endogenous exposures. J. Cell. Biochem., S25: 15-22, 1996.
13. Guldberg, H. C., and Marsden, C. A. Catechol-O-methyltransferase. Pharmacological aspects and physiological role. Pharmacol. Rev., 27: 135-206, 1975.
14. Mannisto, P. T., Ulmanen, I., Lundstrom, K., Taskinen, J., Tenhunen, J., Tilgmann, C., and Kaakkola, S. Characteristics of catechol O-methyltransferase (COMT) and properties of selective COMT inhibitors. Prog. Drug Res., 39: 291-350, 1992.
15. Lachman, H. M., Papolos, D. F., Saito, T., Yu, Y. M., Szumlanski, C. L., and Weinshilboum, R. M. Human catechol-O-methyltransferase pharmacogenetics: description of a functional polymorphism and its potential application to neuropsychiatric disorders. Pharmacogenetics, 6: 243-250, 1996.
16. Goldstein, M., and Leiberman, A. The role of the regulatory enzymes of catecholamine synthesis in Parkinson's disease. Neurology, 12: 822-825, 1992.
17. Price-Evans, D. A. Genetic factors in drug therapy: clinical and molecular pharmacogenetics. Cambridge: Cambridge University Press, 1993.
18. Graham, S., Hellman, R., Marshall, J., Freudenheim, J., Vena, J., Swanson, M., Zielezny, M., Nemoto, T., Stubbe, N., and Raimondo, T. Nutritional epidemiology of postmenopausal breast cancer in Western New York. Am. J. Epidemiol., 134: 552-566, 1991.
19. Ambrosone, C. B., Freudenheim, J. L., Graham, S., Marshall, J. R., Vena, J. E., Brasure, J. R., Michalek, A. M., Laughlin, R., Nemoto, T., Gillenwater, K., Harrington, A. M., and Shields, P. G. Cigarette Smoking, N-acetyl transferase genetic polymorphisms, and breast cancer risk. J. Am. Med. Assoc., 276: 1494-1501, 1996.
20. Daniels, J. K., Williams, N. M., Williams, J., Jones, L. A., Cardno, A. G., Murphy, K. C., Scott, L., Spurlock, G., Riley, B., Scambler, P., Asherson, P., McGuffin, P., and Owen, M. J. No evidence for allelic association between schizophrenia and a polymorphism determining high or low catechol-O-methyltransferase activity. Am. J. Psychiatry, 153: 268-270, 1996.
21. Trentham-Dietz, A., Newcomb, P. A., Storer, B. E., Longnecker, M. P., Baron, J., Greenberg, E. R., and Willet, W. C. Body size and risk of breast cancer. Am. J. Epidemiol., 145: 1011-1019, 1997.
22. Ursin, G., Longnecker, M. P., Haile, R. W., and Greenland, S. A meta-analysis of body mass index and risk of premenopausal breast cancer. Epidemiology, 6: 137-141, 1995.
23. Lavigne, J. A., Helzlsouer, J., Huang, H-Y., Strickland, P. T., Bell, D. A., Selmin, O., Watson, M. A., Hoffman, S., Comstock, G. W., and Yager, J. D. An association between the allele coding for a low activity variant of catechol-O-methyltransferase and the risk for breast cancer. Cancer Res., 57: 5493-5497, 1997.
24. Rivera-Calimlim, L., and Reilly, D. K. Difference in erythrocyte catechol-O-methyltransferase activity between Orientals and Caucasians: difference in levodopa tolerance. Clin. Pharmacol. Ther., 35: 804-809, 1984.
25. Syvanen, A-D., Tilgmann, C., Rinne, J., and Ulmanen, I. Genetic polymorphism of catechol-O-methyltransferase (COMT): correlation of genotype with individual variation of S-COMT activity and comparison of the allele frequencies in the normal population and and Parkinsonian patients in Finland. Pharmacogenetics, 7: 65-71, 1997.
26. Gutierrez, B., Bertranpetit, J., Guillamat, R., Valles, V., Arranz, M. J., Kerwin, R., and Fananas, L. Association analysis of the catechol-O-methyltransferase gene and bipolar affective disorder. Am. J. Psychiatry, 154: 113-115, 1997.
27. Karayiorgou, M., Altemus, M., Galke, B. L., Goldman, D., Murphy, D. L., Ott, J., and Gogos, J. A. Genotype determining low catechol-O-methyltransferase activity as a risk factor for obsessive-compulsive disorder. Proc. Natl. Acad. Sci. USA, 94: 4572-4575, 1997.
28. Yue, T. L., Wang, X., Louden, C. S., Gupta, S., Pillarisetti, K., Gu, J. L., Hart, T. K., Lysko, P. G., and Feuerstein, G. Z. 2-Methoxyestradiol, an endogenous estrogen metabolite, induces apoptosis in endothelial cells and inhibits angiogenesis: possible role for stress-activated protein kinase signaling pathway and Fas expression. Mol. Pharmacol., 51: 951-962, 1997.
29. Zhu, B. T., and Conney, A. H. Functional role of estrogen metabolism in target cells: review and perspectives. Carcinogenesis (Lond.), 19: 1-27, 1998.
30. Kampman, E., Potter, J. D., Slattery, M. L., Caan, B. J., and Edwards, S. Hormone replacement therapy, reproductive history, and colon cancer: a multicenter, case-control study in the United States. Cancer Causes Control, 8: 146-158, 1997.
31. Wei, Q., Matanoski, G. M., Farmer, E. R., Hedayati, A., and Grossman, L. DNA repair related to multiple skin cancers and drug use. Cancer Res., 54: 437-440, 1994.
32. Zhu, T. Z., Ezell, E. L., and Liehr, J. G. Catechol-O-methyltransferase-catalyzed rapid O-methylation of mutagenic flavonoids. J. Biol. Chem., 269: 292-299, 1994.