Effects of pyrroloquinoline quinone on glutamate-induced production of reactive oxygen species in neurons

European Journal of Pharmacology

Volumn 326, Issue 1, 1997, Pages 67-74

  Scanlon, Joelle M ^a   Aizenman, Elias ^a   Reynolds, Ian J ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

Dihydroethidium; Free radical; Glutamate; NMDA receptor; Pyrroloquinoline quinone; Redox modulatory site

Indexed keywords

GLUTAMATE RECEPTOR; GLUTAMIC ACID; HYDROGEN PEROXIDE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PYRROLOQUINOLINEQUINONE; REACTIVE OXYGEN METABOLITE; SCAVENGER;

ANIMAL CELL; ANTIOXIDANT ACTIVITY; ARTICLE; CELL CULTURE; CONTROLLED STUDY; EMBRYO; FLUORESCENCE; FLUORESCENCE MICROSCOPY; FOREBRAIN; IN VITRO STUDY; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; CELLS, CULTURED; EXCITATORY AMINO ACID ANTAGONISTS; FREE RADICAL SCAVENGERS; GLUTAMIC ACID; HYDROGEN PEROXIDE; MICROSCOPY, FLUORESCENCE; NEURONS; NEUROPROTECTIVE AGENTS; OXIDANTS; OXIDATION-REDUCTION; PQQ COFACTOR; QUINOLONES; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; RECEPTORS, N-METHYL-D-ASPARTATE;

EID: 0030994406     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(97)00137-4     Document Type: Article

References (47)

1. Aizenman, E., 1995. Modulation of N-methyl-D-aspartate receptors by hydroxyl radicals in rat cortical neurons in vitro. Neurosci. Lett. 189, 57.
2. Aizenman, E., Lipton, S.A., Loring, R.H., 1989. Selective modulation of NMDA responses by reduction and oxidation. Neuron 2, 1257.
3. Aizenman, E., Hartnett, K.A., Reynolds, I.J., 1990. Oxygen free radicals regulate N-methyl-D-aspartate receptor function via a redox modulatory site. Neuron 5, 841.
4. Aizenman, E., Hartnett, K.A., Zhong, C., Gallop, P.M., Rosenberg, P.A., 1992. Interaction of the putative essential nutrient pyrroloquinoline quinone with the N-methyl-D-aspartate receptor redox site. J. Neurosci. 12, 2362.
5. Aizenman, E., Jensen, F.E., Gallop, P.M., Rosenberg, P.A., Tang, L.-H., 1994. Further evidence that pyrroloquinoline quinone interacts with the N-methyl-D-aspartate receptor redox site in rat cortical neurons in vitro. Neurosci. Lett. 168, 189.
6. Auer, R.N., Siesjö, B.K., 1988. Biological differences between ischemia, hypoglycemia and epilepsy. Ann. Neurol. 24, 699.
7. Bass, D.A., Parce, J.W., Dechatelet, L.R., Szejda, P., Seeds, M.C., Thomas, M., 1983. Flow cytometric studies of oxidative product formation by neutrophils: a graded response to membrane stimulation. J. Immunol. 130, 1910.
8. Benveniste, H., Drejer, J., Schousboe, A., Diemer, N.H., 1984. Elevation of the extracellular concentrations of glutamate and aspartate in rat hippocampus during transient cerebral ischemia monitored by intracerebral microdialysis. J. Neurochem. 43, 1369.
9. Bindokas, V.P., Jordan, J., Lee, C.C., Miller, R.J., 1996. Superoxide production in rat hippocampal neurons: selective imaging with hydroethidine. J. Neurosci. 16, 1324.
10. Bishop, A., Paz, M.A., Gallop, P.M., Karnovsky, M.L., 1994. Methoxatin (PQQ) in guinea-pig neutrophils. Free Radic. Biol. Med. 17, 311.
11. Braughler, J.M., Hall, E.D., 1989. Central nervous system trauma and stroke. I. Biochemical considerations for oxygen radical formation and lipid peroxidation. Free Radic. Biol. Med. 6, 389.
12. Bucana, C., Saiki, I., Nayar, R., 1986. Uptake and accumulation of the vital dye hydroethidine in neoplastic cells. J. Histochem. Cytochem. 34, 1109.
13. Carter, W.O., Narayanan, P.K., Robinson, J.P., 1994. Intracellular hydrogen peroxide and Superoxide anion detection in endothelial cells. J. Leukocyte Biol. 55, 253.
14. Cathcart, R., Schwiers, E., Ames, B.N., 1983. Detection of picomole levels of hydroperoxides using a fluorescent dichlorofluorescein assay. Anal. Biochem. 134, 111.
15. Chan, P.H., Chu, B.S., Chen, S.F., Carlson, E.J., Epstein, C.J., 1990. Reduced neurotoxicity in transgenic mice overexpressing CuZnSOD. Stroke 21, 80.
16. Choi, D.W., 1990. Cerebral hypoxia: some new approaches and unanswered questions. J. Neurosci. 10, 2493.
17. Choi, D.W., Koh, J., Peters, S., 1988. Pharmacology of glutamate neurotoxicity in cortical cell culture: attenuation by NMDA antagonists. J. Neurosci. 8, 185.
18. Davidson, V.L., Kumar, M.A., Wu, J., 1992. Apparent oxygen-dependent inhibition by superoxide dismutase of the quinoprotein methanol dehydrogenase. Biochemistry 34, 1504.
19. Dugan, L.L., Sensi, S.L., Canzoniero, L.M.T., Handran, S.D., Rothman, S.M., Lin, T.-S., Goldberg, M.P., Choi, D.W., 1995. Mitochondrial production of reactive oxygen species in cortical neurons following exposure to N-methyl-D-aspartate. J. Neurosci. 15, 6377.
20. Duine, J.A., Frank, J., Jongejan, J.A., 1987. Enzymology of quinoproteins. Adv. Enzymol. 59, 170.
21. Fluckiger, R., 1993. PQQ and electron transport in mammalian tissues. Nutr. Rev. 51, 26.
22. Gallop, P.M., Paz, M.A., Fluckiger, R., Kagan, H.M., 1989. PQQ, the elusive coenzyme. Trends Biochem. Sci. 14, 343.
23. Gallop, P.M., Paz, M.A., Fluckiger, R., Kagan, H.M., 1993. Is the antioxidant, antiinflammatory putative new vitamin PQQ involved with nitric oxide in bone metabolism?. Connect. Tissue Res. 29, 153.
24. Hall, E.D., Braughler, J.M., 1989. Central nervous system trauma and stroke. II. Physiological and pharmacological evidence for involvement of oxygen radicals and lipid peroxidation. Free Radic. Biol. Med. 6, 303.
25. Halliwell, B., 1992. Reactive oxygen species in the central nervous system. J. Neurochem. 59, 1609.
26. Hamagishi, Y., Murata, S., Kamei, H., Oki, T., Adachi, O., Ameyama, M., 1990. New biological properties of PQQ and its related compounds: inhibition of chemiluminescence, lipid peroxidation and rat paw edema. J. Pharmacol. Exp. Ther. 255, 980.
27. Jensen, F.E., Gardner, G.J., Williams, A.P., Gallop, P.M., Aizenman, E., Rosenberg, P.A., 1994. The putative essential nutrient pyrroloquinoline quinone is neuroprotective in a rodent model of hypoxic/ischemic brain injury. Neuroscience 62, 399.
28. Killgore, J., Smidt, C., Duich, L., Romero-Chapman, N., Tinker, D., Resider, K., Melko, M., Hyde, D., Rucker, R.B., 1989. Nutritional importance of pyrroloquinoline quinone. Science 245, 850.
29. Kooy, N.W., Royall, J.A., Ischiropoulos, H., Beckman, J.S., 1994. Peroxynitrite-mediated oxidation of dihydrorhodamine 123. Free Radic. Biol. Med. 16, 149.
30. Lafon-Cazal, M., Pietri, S., Culcasi, M., Bockaert, J., 1993. NMDA-dependent superoxide production and neurotoxicity. Nature 364, 535.
31. LeBel, C.P., Ischiropoulos, H., Bondy, S.C., 1992. Evaluation of the probe 2′,7′-dichlorofluorescin as an indicator of reactive oxygen species formation and oxidative stress. Chem. Res. Toxicol. 5, 227.
32. Levy, D.I., Sucher, N.J., Lipton, S.A., 1990. Redox modulation of NMDA receptor mediated toxicity in mammalian central neurons. Neurosci. Lett. 110, 291.
33. Liu, D., Thangnipon, W., McAdoo, D.J., 1991. Excitatory amino acids rise to toxic levels upon impact injury to the rat spinal cord. Brain Res. 547, 344.
34. Monyer, H., Hartley, D.M., Choi, D.W., 1990. 21-Aminosteroids attenuate excitotoxic neuronal injury in cortical cell cultures. Neuron 5, 121.
35. Nishigori, H., Yasunaga, M., Mizumura, M., Lee, J.W., Iwatsuru, M., 1989. Preventative effects of pyrroloquinoline quinone of formation of cataract and decline of lenticular and hepatic glutathione of developing chick embryo after glucocorticoid treatment. Life Sci. 45, 593.
36. Park, J., Churchich, J.E., 1992. Pyrroloquinoline quinone (coenzyme PQQ) and the oxidation of SH residues in proteins. Biofactors 3, 257.
37. Pellegrini-Gampietro, D.E., Cherici, G., Alesiani, M., Carla, V., Moroni, F., 1990. Excitatory amino acid release and free radical formation may cooperate in the genesis of ischemia induced neuronal damage. J. Neurosci. 10, 1035.
38. Reynolds, I.J., Hastings, T.G., 1995. Glutamate induces the production of reactive oxygen species in cultured forebrain neurons following NMDA receptor activation. J. Neurosci. 15, 3318.
39. Rothe, G., Valet, G., 1990. Flow cytometric analysis of respiratory burst activity in phagocytes with hydroethidine and 2′,7′-dichlorofluorescin. J. Leukocyte Biol. 47, 440.
40. Rothman, S.M., Olney, J.W., 1987. Excitotoxicity and the NMDA receptor. Trends Neurosci. 10, 299.
41. Sinor, J.D., Boeckman, F.A., Aizenman, E., 1997. Intrinsic redox proper-ties of N-methyl-D-aspartate receptor can determine the developmental expression of excitotoxicity in rat cortical neurons in vitro. Brain Res. 747, 297.
42. Smidt, C.R., Steinberg, F.M., Rucker, R.B., 1991. Physiologic importance of pyrroloquinoline quinone. Proc. Soc. Exp. Biol. Med. 197, 19.
43. Tang, L.-H., Aizenman, P., 1993. The modulation of N-methyl-D-aspartate receptors by redox and alkylating reagents in rat cortical neurones in vitro. J. Physiol. (London) 465, 303.
44. Tauck, D.L., Ashbeck, G.A., 1990. Glycine synergistically modulates the enhancement of LTP induced by a sulfhydryl reducing agent. Brain Res. 519, 129.
45. Tolliver, J.M., Pellmar, T.C., 1987. Dithiothreitol elicits epileptiform activity in CAl of the guinea-pig hippocampal slice. Brain Res. 404, 133.
46. Volterra, A., Trotti, D., Tromba, C., Floridi, S., Racagni, G., 1994. Glutamate uptake inhibition by oxygen free radicals in rat cortical astrocytes. J. Neurosci. 14, 2924.
47. 2+ exchange buffer glutamate-induced calcium loads in cultured cortical neurons. J. Neurosci. 15, 1318.