-
1
-
-
0034849573
-
The GDNF/ ET signaling pathway and human diseases
-
Takahashi, M. The GDNF/ ET signaling pathway and human diseases. Cytokine Growth Factor, 12: 361-373, 2001.
-
(2001)
Cytokine Growth Factor
, vol.12
, pp. 361-373
-
-
Takahashi, M.1
-
2
-
-
0035479144
-
The RET receptor: Function in development and dysfunction in congenital malformation
-
Manie, S., Santoro, M., Fusco, A., and Billaud, M, The RET receptor: function in development and dysfunction in congenital malformation. Trends Genet., 17: 580-589, 2001.
-
(2001)
Trends Genet.
, vol.17
, pp. 580-589
-
-
Manie, S.1
Santoro, M.2
Fusco, A.3
Billaud, M.4
-
3
-
-
0028174023
-
Defects in the kidney and enteric nervous system of mice lacking the tyrosine kinase receptor Ret
-
Schuchardt, A., D'Agati, V., Larsson-Blomberg, L., Costantini, F., and Pachnis, V. Defects in the kidney and enteric nervous system of mice lacking the tyrosine kinase receptor Ret. Nature (Lond.), 367: 380-383, 1994.
-
(1994)
Nature (Lond.)
, vol.367
, pp. 380-383
-
-
Schuchardt, A.1
D'Agati, V.2
Larsson-Blomberg, L.3
Costantini, F.4
Pachnis, V.5
-
4
-
-
15844384629
-
Renal and neuronal abnormalities in mice lacking GDNF
-
Moore, M. W., Klein, R. D., Farinas, I., Sauer, H., Armanini, M., Phillips, H., Reichardt, L. F., Ryan, A. M., Carver-Moore, K., and Rosenthal, A. Renal and neuronal abnormalities in mice lacking GDNF. Nature (Lond.), 382: 76-79, 1996.
-
(1996)
Nature (Lond.)
, vol.382
, pp. 76-79
-
-
Moore, M.W.1
Klein, R.D.2
Farinas, I.3
Sauer, H.4
Armanini, M.5
Phillips, H.6
Reichardt, L.F.7
Ryan, A.M.8
Carver-Moore, K.9
Rosenthal, A.10
-
5
-
-
15844426332
-
Defects in enteric innervation and kidney development in mice lacking GDNF
-
Pichel, J. G., Shen, L., Sheng, H. Z., Granholm, A. C., Drago, A., Grinberg, A., Lee, E. J., Huang, S. P., Saarma, M., Hoffer, B. J., Sariola, H., and Westphal, H. Defects in enteric innervation and kidney development in mice lacking GDNF, Nature (Lond.), 382: 73-76, 1996.
-
(1996)
Nature (Lond.)
, vol.382
, pp. 73-76
-
-
Pichel, J.G.1
Shen, L.2
Sheng, H.Z.3
Granholm, A.C.4
Drago, A.5
Grinberg, A.6
Lee, E.J.7
Huang, S.P.8
Saarma, M.9
Hoffer, B.J.10
Sariola, H.11
Westphal, H.12
-
6
-
-
0029901727
-
Renal agenesis and the absence of enteric neurons in mice lacking GDNF
-
Sanchez, M. P., Silos-Santiago, I., Frisen, J., He, B., Lira, S. A., and Barbacid, M. Renal agenesis and the absence of enteric neurons in mice lacking GDNF. Nature (Lond.), 382: 70-73, 1996.
-
(1996)
Nature (Lond.)
, vol.382
, pp. 70-73
-
-
Sanchez, M.P.1
Silos-Santiago, I.2
Frisen, J.3
He, B.4
Lira, S.A.5
Barbacid, M.6
-
7
-
-
0027303248
-
Mutations in the RET proto-oncogene are associated with MEN 2A and FMTC
-
Donis-Keller, H., Dou, S., Chi, D., Carlson, K. M., Toshima, K., Lairmore, T. C., Howe, I. R., Moley, I. F., Goodfellow, P., and Wells, S. A., Jr. Mutations in the RET proto-oncogene are associated with MEN 2A and FMTC. Hum. Mol. Genet., 2: 851-856, 1993.
-
(1993)
Hum. Mol. Genet.
, vol.2
, pp. 851-856
-
-
Donis-Keller, H.1
Dou, S.2
Chi, D.3
Carlson, K.M.4
Toshima, K.5
Lairmore, T.C.6
Howe, I.R.7
Moley, I.F.8
Goodfellow, P.9
Wells S.A., Jr.10
-
8
-
-
0027231568
-
Germ-line mutations of the RET proto-oncogene in multiple endocrine neoplasia type 2A
-
Mulligan, L. M., Kwok, J. B. J., Healey, C. S., Elsdon, M. J., Eng, C, Gardner, E., Love, D. R., Mole, S. E., Moore, J. K., Papl, L., Ponder, M. A., Telenlus, H., Tunnacliffe, A., and Ponder, B. A. J. Germ-line mutations of the RET proto-oncogene in multiple endocrine neoplasia type 2A. Nature (Lond.), 363: 458-460, 1993.
-
(1993)
Nature (Lond.)
, vol.363
, pp. 458-460
-
-
Mulligan, L.M.1
Kwok, J.B.J.2
Healey, C.S.3
Elsdon, M.J.4
Eng, C.5
Gardner, E.6
Love, D.R.7
Mole, S.E.8
Moore, J.K.9
Papl, L.10
Ponder, M.A.11
Telenlus, H.12
Tunnacliffe, A.13
Ponder, B.A.J.14
-
9
-
-
0028174024
-
A mutation in the RET proto-oncogene associated with multiple endocrine neoplasia type 2B and sporadic medullary thyroid carcinoma
-
Hofstra, R. M., Landsvater, R. M., Ceccherini, I., Stulp, R. P., Stelwagen, T., Luo, Y., Pasini, B., Hoppener, J. W. M., Ploos van Hamstel, H. K., Romeo, G., Lips, C. J. M., and Buys, C. H. C. M. A mutation in the RET proto-oncogene associated with multiple endocrine neoplasia type 2B and sporadic medullary thyroid carcinoma. Nature (Lond.), 367: 375-376, 1994.
-
(1994)
Nature (Lond.)
, vol.367
, pp. 375-376
-
-
Hofstra, R.M.1
Landsvater, R.M.2
Ceccherini, I.3
Stulp, R.P.4
Stelwagen, T.5
Luo, Y.6
Pasini, B.7
Hoppener, J.W.M.8
Ploos van Hamstel, H.K.9
Romeo, G.10
Lips, C.J.M.11
Buys, C.H.C.M.12
-
10
-
-
0032894774
-
RET proto-oncogene in the development of human cancer
-
Eng, C. RET proto-oncogene in the development of human cancer. J. Clin. Oncol., 17: 380-393, 1999.
-
(1999)
J. Clin. Oncol.
, vol.17
, pp. 380-393
-
-
Eng, C.1
-
11
-
-
0027977002
-
Single missense mutation in the tyrosine kinase catalytic domain of the RET proto-oncogene is associated with multiple endocrine neoplasia type 2B
-
Carlson, K. M., Dou, S., Chi, D., Scavarda, N. J., Toshima, K., Jackson, C. E., Wells, S. A., Jr., Goodfellow, P., and Donis-Keller, H. Single missense mutation in the tyrosine kinase catalytic domain of the RET proto-oncogene is associated with multiple endocrine neoplasia type 2B. Proc. Natl. Acad. Sci. USA, 91: 1579-1583, 1994.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 1579-1583
-
-
Carlson, K.M.1
Dou, S.2
Chi, D.3
Scavarda, N.J.4
Toshima, K.5
Jackson, C.E.6
Wells S.A., Jr.7
Goodfellow, P.8
Donis-Keller, H.9
-
12
-
-
0025022463
-
PTC is a novel rearranged form of the ret proto-oncogene and is frequently detected in vivo in human thyroid papillary carcinomas
-
Grieco, M., Santoro, M., Berlingieri, M. T., Melillo, R. M., Donghi, R., Bongarzone, I., Pierotti, M. A., Della Porta, G., Fusco, A., and Vecchio, G. PTC is a novel rearranged form of the ret proto-oncogene and is frequently detected in vivo in human thyroid papillary carcinomas. Cell, 60: 557-563, 1990.
-
(1990)
Cell
, vol.60
, pp. 557-563
-
-
Grieco, M.1
Santoro, M.2
Berlingieri, M.T.3
Melillo, R.M.4
Donghi, R.5
Bongarzone, I.6
Pierotti, M.A.7
Della Porta, G.8
Fusco, A.9
Vecchio, G.10
-
13
-
-
0027523909
-
Molecular characterization of a thyroid tumor-specific transforming sequence formed by the fusion of ret tyrosine kinase and the regulatory subunit RIa of cyclic AMP-dependent protein kinase A
-
Bongarzone, I., Monzini, N., Borrello, M. G., Carcano, C., Ferraresi, G., Arighi, E., Mondellini, P., Della Porta, G., and Pierotti, M. A. Molecular characterization of a thyroid tumor-specific transforming sequence formed by the fusion of ret tyrosine kinase and the regulatory subunit RIa of cyclic AMP-dependent protein kinase A. Mol. Cell. Biol., 13: 358-366, 1993.
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 358-366
-
-
Bongarzone, I.1
Monzini, N.2
Borrello, M.G.3
Carcano, C.4
Ferraresi, G.5
Arighi, E.6
Mondellini, P.7
Della Porta, G.8
Pierotti, M.A.9
-
14
-
-
0028233525
-
Frequent activation of ret proto-oncogene by fusion with a new activating gene in papillary thyroid carcinomas
-
Bongarzone, I., Butti, M. G., Coronelli, S., Borrello, M. G., Santoro, M., Mondellini, P., Pilotti, S., Fusco, A., Della Porta, G., and Pierotti, M. A. Frequent activation of ret proto-oncogene by fusion with a new activating gene in papillary thyroid carcinomas. Cancer Res., 54: 2979-2985, 1994.
-
(1994)
Cancer Res.
, vol.54
, pp. 2979-2985
-
-
Bongarzone, I.1
Butti, M.G.2
Coronelli, S.3
Borrello, M.G.4
Santoro, M.5
Mondellini, P.6
Pilotti, S.7
Fusco, A.8
Della Porta, G.9
Pierotti, M.A.10
-
15
-
-
0031964510
-
Detection of a novel type of RET rearrangement (PTC5) in thyroid carcinomas after Chernobyl and analysis of the involved RET-fused gene RFG5
-
Klugbauer, S., Demidchik, E. P., Lengfelder, E., and Rabes, H. M. Detection of a novel type of RET rearrangement (PTC5) in thyroid carcinomas after Chernobyl and analysis of the involved RET-fused gene RFG5. Cancer Res., 58: 198-203, 1998.
-
(1998)
Cancer Res.
, vol.58
, pp. 198-203
-
-
Klugbauer, S.1
Demidchik, E.P.2
Lengfelder, E.3
Rabes, H.M.4
-
16
-
-
0029781186
-
Molecular and biochemical analysis of Ret/ tc4, a novel oncogenic rearrangement between Ret and Ele1 genes, in a post-Chernobyl papillary thyroid cancer
-
Fugazzola, L., Pierotti, M. A., Vigano', E., Pacini, F., Vorontsova, T. V., and Bongarzone, I. Molecular and biochemical analysis of Ret/ tc4, a novel oncogenic rearrangement between Ret and Ele1 genes, in a post-Chernobyl papillary thyroid cancer. Oncogene, 13: 1093-1097, 1996.
-
(1996)
Oncogene
, vol.13
, pp. 1093-1097
-
-
Fugazzola, L.1
Pierotti, M.A.2
Vigano', E.3
Pacini, F.4
Vorontsova, T.V.5
Bongarzone, I.6
-
17
-
-
0028838086
-
Mechanism of activation of the ret proto-oncogene by multiple endocrine neoplasia 2A mutations
-
Asai, N., Iwashita, T., Matsuyama, M., and Takahashi, M. Mechanism of activation of the ret proto-oncogene by multiple endocrine neoplasia 2A mutations. Mol. Cell. Biol., 15 (No. 3): 1613-1619, 1995.
-
(1995)
Mol. Cell. Biol.
, vol.15
, Issue.3
, pp. 1613-1619
-
-
Asai, N.1
Iwashita, T.2
Matsuyama, M.3
Takahashi, M.4
-
18
-
-
0028914683
-
Activation of RET as a dominant transforming gene by germline mutations of MEN2A and MEN2B
-
Santoro, M., Carlomagno, F., Romano, A., Bottaro, D. P., Dathan, N. A., Grieco, M., Fusco, A., Vecchio, G., Matoskova, B., Kraus, M. H., and Di Fiore, P. P. Activation of RET as a dominant transforming gene by germline mutations of MEN2A and MEN2B. Science (Wash. DC), 267: 381-383, 1995.
-
(1995)
Science (Wash. DC)
, vol.267
, pp. 381-383
-
-
Santoro, M.1
Carlomagno, F.2
Romano, A.3
Bottaro, D.P.4
Dathan, N.A.5
Grieco, M.6
Fusco, A.7
Vecchio, G.8
Matoskova, B.9
Kraus, M.H.10
Di Fiore, P.P.11
-
19
-
-
0030047832
-
Identification of tyrosine residues that are essential for transforming activity of the RET proto-oncogene with MEN2A or MEN2B mutation
-
Iwashita, T., Asai, N., Murakami, H., Matsuyama, M., and Takahashi, M. Identification of tyrosine residues that are essential for transforming activity of the RET proto-oncogene with MEN2A or MEN2B mutation. Oncogene, 12: 481-487, 1996.
-
(1996)
Oncogene
, vol.12
, pp. 481-487
-
-
Iwashita, T.1
Asai, N.2
Murakami, H.3
Matsuyama, M.4
Takahashi, M.5
-
20
-
-
0033166442
-
Biological and biochemical properties of Ret with kinase domain mutations identified in multiple endocrine neoplasia type 2B and familial medullary thyroid carcinoma
-
Iwashita, T., Kato, M., Murakami, H., Asai, N., Ishiguro, Y., Ito, S., Iwata, Y., Kawai, K., Asai, M., Kurokawa, K., Kajita, H., and Takahashi, M. Biological and biochemical properties of Ret with kinase domain mutations identified in multiple endocrine neoplasia type 2B and familial medullary thyroid carcinoma. Oncogene, 18: 3919-3922, 1999.
-
(1999)
Oncogene
, vol.18
, pp. 3919-3922
-
-
Iwashita, T.1
Kato, M.2
Murakami, H.3
Asai, N.4
Ishiguro, Y.5
Ito, S.6
Iwata, Y.7
Kawai, K.8
Asai, M.9
Kurokawa, K.10
Kajita, H.11
Takahashi, M.12
-
21
-
-
0034722889
-
The EGF receptor family as targets for cancer therapy
-
Mendelsohn, J., and Baselga, J. The EGF receptor family as targets for cancer therapy. Oncogene, 19: 6550-6565, 2000.
-
(2000)
Oncogene
, vol.19
, pp. 6550-6565
-
-
Mendelsohn, J.1
Baselga, J.2
-
22
-
-
0035378651
-
Clinical trials referral resource. Epidermal growth factor receptor inhibitors in clinical trials
-
Dancey, J. E., and Schoenfeldt, M. Clinical trials referral resource. Epidermal growth factor receptor inhibitors in clinical trials. Oncology (Huntingt.), 15: 748-750, 2001.
-
(2001)
Oncology (Huntingt.)
, vol.15
, pp. 748-750
-
-
Dancey, J.E.1
Schoenfeldt, M.2
-
23
-
-
0036171234
-
The kinase inhibitor PP1 blocks tumorigenesis induced by RET oncogenes
-
Carlomagno, F., Vitagliano, D., Guida, T., Napolitano, M., Vecchio, G., Fusco, A., Gazit, A., Levitzki, A., and Santoro, M. The kinase inhibitor PP1 blocks tumorigenesis induced by RET oncogenes. Cancer Res., 62: 1077-1082, 2002.
-
(2002)
Cancer Res.
, vol.62
, pp. 1077-1082
-
-
Carlomagno, F.1
Vitagliano, D.2
Guida, T.3
Napolitano, M.4
Vecchio, G.5
Fusco, A.6
Gazit, A.7
Levitzki, A.8
Santoro, M.9
-
24
-
-
0024077722
-
Autocrine activities of basic fibroblast growth factor: Regulation of endothelial cell movement, plasminogen activator synthesis, and DNA synthesis
-
Sato, Y., and Rifkin, D. B. Autocrine activities of basic fibroblast growth factor: regulation of endothelial cell movement, plasminogen activator synthesis, and DNA synthesis. J. Cell. Biol., 107: 1199-1205, 1988.
-
(1988)
J. Cell. Biol.
, vol.107
, pp. 1199-1205
-
-
Sato, Y.1
Rifkin, D.B.2
-
25
-
-
9244251611
-
γ
-
γ. Mol. Cell. Biol., 16 (No. 5): 2151-2163, 1996.
-
(1996)
Mol. Cell. Biol.
, vol.16
, Issue.5
, pp. 2151-2163
-
-
Borrello, M.G.1
Alberti, L.2
Arighi, E.3
Bongarzone, I.4
Battistini, C.5
Bardelli, A.6
Pasini, B.7
Piutti, C.8
Rizzetti, M.G.9
Mondellini, P.10
Radice, M.T.11
Pierotti, M.A.12
-
26
-
-
0033607023
-
The Glu632-Leu633 deletion in cystein rich domain of Ret induces constitutive dimerization and alters the processing of the receptor protein
-
Bongarzone, I., Vigano, E., Alberti, L., Mondellini, P., Uggeri, M., Pasini, B., Borrello, M. G., and Pierotti, M. A. The Glu632-Leu633 deletion in cystein rich domain of Ret induces constitutive dimerization and alters the processing of the receptor protein. Oncogene, 18: 4833-4838, 1999.
-
(1999)
Oncogene
, vol.18
, pp. 4833-4838
-
-
Bongarzone, I.1
Vigano, E.2
Alberti, L.3
Mondellini, P.4
Uggeri, M.5
Pasini, B.6
Borrello, M.G.7
Pierotti, M.A.8
-
27
-
-
0037018146
-
Ubiquitination and proteasomal activity is required for transport of the EGF receptor to inner membranes of multivesicular bodies
-
Longva, K. E., Blystad, F. D., Stang, E., Larsen, A. M., Johannessen, L. E., and Madshus, I. H. Ubiquitination and proteasomal activity is required for transport of the EGF receptor to inner membranes of multivesicular bodies. J. Cell. Biol., 156: 843-854, 2002.
-
(2002)
J. Cell. Biol.
, vol.156
, pp. 843-854
-
-
Longva, K.E.1
Blystad, F.D.2
Stang, E.3
Larsen, A.M.4
Johannessen, L.E.5
Madshus, I.H.6
-
28
-
-
0034700146
-
Ubiquitin is part of the retrovirus budding machinery
-
Patnaik, A., Chau, V., and Wills, J. W. Ubiquitin is part of the retrovirus budding machinery. Proc. Natl. Acad. Sci. USA, 97: 13069-13074, 2000.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 13069-13074
-
-
Patnaik, A.1
Chau, V.2
Wills, J.W.3
-
29
-
-
0034700088
-
Proteasome inhibition interferes with gag polyprotein processing, release, and maturation of HIV-1 and HIV-2
-
Schubert, U., Ott, D. E., Chertova, E. N., Welker, R., Tessmer, U., Princiotta, M. F., Bennink, J. R., Krausslich, H. G., and Yewdell, J. W. Proteasome inhibition interferes with gag polyprotein processing, release, and maturation of HIV-1 and HIV-2. Proc. Natl. Acad. Sci. USA, 97: 13057-13062, 2000.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 13057-13062
-
-
Schubert, U.1
Ott, D.E.2
Chertova, E.N.3
Welker, R.4
Tessmer, U.5
Princiotta, M.F.6
Bennink, J.R.7
Krausslich, H.G.8
Yewdell, J.W.9
-
30
-
-
0034700097
-
A role for ubiquitin ligase recruitment in retrovirus release
-
Strack, B., Calistri, A., Accola, M. A., Palu, G., and Gottlinger, H. G. A role for ubiquitin ligase recruitment in retrovirus release. Proc. Natl. Acad. Sci. USA, 97: 13063-13068, 2000.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 13063-13068
-
-
Strack, B.1
Calistri, A.2
Accola, M.A.3
Palu, G.4
Gottlinger, H.G.5
-
31
-
-
0033061032
-
Protein tyrosine kinase inhibitors as novel therapeutic agents
-
Levitzki, A. Protein tyrosine kinase inhibitors as novel therapeutic agents. Pharmacol. Ther., 82: 231-239, 1999.
-
(1999)
Pharmacol. Ther.
, vol.82
, pp. 231-239
-
-
Levitzki, A.1
-
32
-
-
0034043977
-
Site-directed irreversible inhibitors of the erbB family of receptor tyrosine kinases as novel chemotherapeutic agents for cancer
-
Fry, D. W. Site-directed irreversible inhibitors of the erbB family of receptor tyrosine kinases as novel chemotherapeutic agents for cancer. Anticancer Drug Des., 15: 3-16, 2000.
-
(2000)
Anticancer Drug Des.
, vol.15
, pp. 3-16
-
-
Fry, D.W.1
-
33
-
-
0033392493
-
Ubiquitin ligase activity and tyrosine phosphorylation underlie suppression of growth factor signaling by c-Cbl/ li-1
-
Levkowitz, G., Waterman, H., Ettenberg, S. A., Katz, M., Tsygankov, A. Y., Alroy, I., Lavi, S., Iwai, K., Reiss, Y., Ciechanover, A., Lipkowitz, S., and Yarden, Y. Ubiquitin ligase activity and tyrosine phosphorylation underlie suppression of growth factor signaling by c-Cbl/ li-1. Mol. Cell, 4: 1029-1040, 1999.
-
(1999)
Mol. Cell
, vol.4
, pp. 1029-1040
-
-
Levkowitz, G.1
Waterman, H.2
Ettenberg, S.A.3
Katz, M.4
Tsygankov, A.Y.5
Alroy, I.6
Lavi, S.7
Iwai, K.8
Reiss, Y.9
Ciechanover, A.10
Lipkowitz, S.11
Yarden, Y.12
-
34
-
-
0034634678
-
c-Cbl is a suppressor of the neu oncogene
-
Levkowitz, G., Oved, S., Klapper, L. N., Harari, D., Lavi, S., Sela, M., and Yarden, Y. c-Cbl is a suppressor of the neu oncogene. J. Biol. Chem., 275: 35532-35539, 2000.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 35532-35539
-
-
Levkowitz, G.1
Oved, S.2
Klapper, L.N.3
Harari, D.4
Lavi, S.5
Sela, M.6
Yarden, Y.7
-
35
-
-
18444404925
-
Drug-induced ubiquitylation and degradation of ErbB receptor tyrosine kinases: Implications for cancer therapy
-
Citri, A., Alroy, I., Lavi, S., Rubin, C., Xu, W., Grammatikakis, N., Patterson, C., Neckers, L., Fry, D. W., and Yarden, Y. Drug-induced ubiquitylation and degradation of ErbB receptor tyrosine kinases: implications for cancer therapy. EMBO J., 21: 2407-2417, 2002.
-
(2002)
EMBO J.
, vol.21
, pp. 2407-2417
-
-
Citri, A.1
Alroy, I.2
Lavi, S.3
Rubin, C.4
Xu, W.5
Grammatikakis, N.6
Patterson, C.7
Neckers, L.8
Fry, D.W.9
Yarden, Y.10
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