Interleukin-1β increases spinal cord wind-up activity in normal but not in monoarthritic rats

Neuroscience Letters

Volumn 342, Issue 3, 2003, Pages 139-142

  Constandil, Luis ^a   Pelissier, Teresa ^b   Soto Moyano, Rubén ^b   Mondaca, Mauricio ^a   Sáez, Hernán ^a   Laurido, Claudio ^a   Muñoz, Carlos ^b   López, Nandy ^a   Hernández, Alejandro ^a  

^a UNIVERSIDAD DE SANTIAGO DE CHILE   (Chile)

^b UNIVERSITY OF CHILE   (Chile)

Author keywords

C fiber reflex; Cytokine; Interleukin 1 ; Monoarthritis; Rat; Spinal cord; Wind up

Indexed keywords

INTERLEUKIN 1BETA; INTERLEUKIN 1;

ADAPTIVE BEHAVIOR; ANIMAL MODEL; ARTICLE; CHRONIC PAIN; CONTROLLED STUDY; DRUG MEGADOSE; ELECTROSTIMULATION; EVOKED RESPONSE; FUNCTIONAL ASSESSMENT; LOW DRUG DOSE; MONARTHRITIS; MOUSE; NOCICEPTION; NONHUMAN; PRIORITY JOURNAL; RAT; REFLEX; SCORING SYSTEM; SPINAL CORD; SYNAPTIC TRANSMISSION; ANIMAL; ARTHRITIS; CHEMICALLY INDUCED DISORDER; COMPARATIVE STUDY; DOSE RESPONSE; DRUG EFFECT; INTRASPINAL DRUG ADMINISTRATION; METABOLISM; METHODOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; SPRAGUE DAWLEY RAT; TIME;

ANIMALS; ARTHRITIS, EXPERIMENTAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTRIC STIMULATION; INJECTIONS, SPINAL; INTERLEUKIN-1; RATS; RATS, SPRAGUE-DAWLEY; REFLEX; SPINAL CORD; TIME FACTORS;

EID: 0037693765     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(03)00278-7     Document Type: Article

References (20)

1. Allan S.M., Harrison D.C., Read S., Collins B., Parsons A.A., Philpott K., Rothwell N.J. Selective increases in cytokine expression in the rat brain in response to striatal injection of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate and interleukin-1. Mol. Brain Res. 93:2001;180-189.
2. DeLeo J.A., Colburn R.W., Nichols M., Malhotra A. Interleukin-6-mediated hyperalgesia/allodynia and increased spinal IL-6 expression in a rat mononeuropathy model. J. Interferon Cytokine Res. 16:1996;695-700.
3. Dickenson A.H. A cure for wind up: NMDA receptor antagonists as potential analgesics. Trends Pharmacol. Sci. 11:1990;307-309.
4. Dickenson A.H., Chapman V., Green G.M. The pharmacology of excitatory and inhibitory amino acid-mediated events in the transmission and modulation of pain in the spinal cord. Gen. Pharmacol. 28:1997;633-638.
5. Ferreira S.H. The role of interleukins and nitric oxide in the mediation of inflammatory pain and its control by peripheral analgesics. Drugs. 46:(Suppl. 1):1993;1-9.
6. Inoue A., Ikoma K., Morioka N., Kumagay K., Hashimoto T., Hide I., Nakata Y. Interleukin-1beta induces substance P release from primary afferent neurons through the cyclooxygenase-2 system. J. Neurochem. 73:1999;2206-2213.
7. Laurido C., Pelissier T., Pérez H., Flores F., Hernández A. Effect of ketamine on spinal cord nociceptive transmission in normal and monoarthritic rats. NeuroReport. 12:2001;1551-1554.
8. Matsukawa A., Yoshimura T., Miyamoto K., Ohkawara S., Yoshinaga M. Analysis of the inflammatory cytokine network among TNF alpha, IL-1 beta, IL-1 receptor antagonist, and IL-8 in LPS-induced rabbit arthritis. Lab. Invest. 76:1997;629-638.
9. Mestre C., Pelissier T., Fialip J., Wilcox G., Eschalier A. A method to perform direct transcutaneous intrathecal injection in rats. J. Pharmacol. Toxicol. Methods. 32:1994;197-200.
10. Plata-Salaman C.R., Ilyin S.E., Turrin N.P., Gayle D., Flynn M.C., Romanovitch A.E., Kelly M.E., Bureau Y., Anisman H., McIntyre D.C. Kindling modulates the IL-1beta system, TNF-alpha, TGF-beta1, and neuropeptide mRNAs in specific brain regions. Mol. Brain Res. 75:2000;248-258.
11. Reeve A.J., Patel S., Fox A., Walker K., Urban L. Intrathecally administered endotoxin or cytokines produce allodynia, hyperalgesia and changes in spinal cord neuronal responses to nociceptive stimuli in the rat. Eur. J. Pain. 4:2000;247-257.
12. Souter A.J., Garry M.G., Tanelian D.L. Spinal interleukin-1beta reduces inflammatory pain. Pain. 86:2000;63-68.
13. Strimbu-Gozariu M., Guirimand F., Willer J.C., Le Bars D. Effects of mu, delta and kappa opioid antagonists on the depression of a C-fiber reflex by intrathecal morphine and DAGO in the rat. Eur. J. Pharmacol. 237:1993;197-205.
14. Tadano T., Namioka M., Nakagawasai O., Tan-No K., Matsushima K., Endo Y., Kisara K. Induction of nociceptive responses by intrathecal injection of interleukin-1 in mice. Life Sci. 65:1999;255-261.
15. Ethical standards for investigations of experimental pain in animals. Pain. 9:1980;141-143.
16. Vitkovic L., Bockaert J., Jacque C. 'Inflammatory' cytokines: neuromodulators in normal brain? J. Neurochem. 74:2000;457-471.
17. Watkins L.R., Maier S.F. The pain of being sick: implications of immune-to-brain communication for understanding pain. Annu. Rev. Psychol. 51:2000;29-57.
18. Watkins L.R., Milligan E.D., Maier S.F. Glial activation: a driving force for pathological pain. Trends Neurosci. 24:2001;450-455.
19. Xiao E., Xia L., Ferin M., Wardlaw S.L. Intracerebroventricular injection of interleukin-1 stimulates the release of high levels of interleukin-6 and interleukin-1 receptor antagonist into peripheral blood in the primate. J. Neuroimmunol. 97:1999;70-76.
20. Yabuuchi K., Nishiyori A., Minami M., Satoh M. Biphasic effects of intracerebroventricular interleukin-1 beta on mechanical nociception in the rat. Eur. J. Pharmacol. 300:1996;59-65.