The contribution of the coronary concentrations of propofol to its cardiovascular effects in anesthetized sheep

Anesthesia and Analgesia

Volumn 96, Issue 6, 2003, Pages 1589-1597

  Zheng, Da ^a   Upton, Richard N ^a   Martinez, Allison M ^a  

^a UNIVERSITY OF ADELAIDE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ISOFLURANE; PROPOFOL;

ANESTHESIA; ANIMAL EXPERIMENT; ARTICLE; CARDIOVASCULAR SYSTEM; CONTROLLED STUDY; CORONARY ARTERY; CORONARY SINUS; DOSE RESPONSE; DRUG BLOOD LEVEL; DRUG EFFECT; HEART LEFT VENTRICLE CONTRACTILITY; HEART MUSCLE; MEAN ARTERIAL PRESSURE; NONHUMAN; PRIORITY JOURNAL; SHEEP;

EID: 0037686591     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1213/01.ANE.0000060561.16583.A7     Document Type: Article

References (30)

1. Price HL, Kovnat PJ, Safer JN, et al. The uptake of thiopental by body tissues and its relation to the duration of narcosis. Clin Pharmacol Ther 1960;1:16-22.
2. Wada DR, Bjorkman S, Ebling WF, et al. Computer simulation of the effects of alterations in blood flows and body composition on thiopental pharmacokinetics in humans. Anesthesiology 1997;87:884-99.
3. Upton RN, Ludbrook GL. A model of the kinetics and dynamics of induction of anaesthesia in sheep: variable estimation for thiopental and comparison with propofol. Br J Anaesth 1999;82:890-9.
4. Coleman TG. Mathematical analysis of cardiovascular function. IEEE Trans Biomed Eng 1985;32:289-94.
5. Melchior FM, Srinivasan RS, Charles JB. Mathematical modeling of human cardiovascular system for simulation of orthostatic response. Am J Physiol 1992;262:H1920-33.
6. Kappel F, Peer RO. A mathematical model for fundamental regulation processes in the cardiovascular system. J Math Biol 1993;31:611-31.
7. Fukui Y, Smith NT. Interactions among ventilation, the circulation, and the uptake and distribution of halothane: use of a hybrid computer multiple model. I. The basic model. Anesthesiology 1981;54:107-18.
8. Francheteau P, Steimer JL, Merdjan H, et al. A mathematical model for dynamics of cardiovascular drug action: application to intravenous dihydropyridines in healthy volunteers. J Pharmacokinet Biopharm 1993;21:489-514.
9. Puttick RM, Diedericks J, Sear JW, et al. Effect of graded infusion rates of propofol on regional and global left ventricular function in the dog. Br J Anaesth 1992;69:375-81.
10. Pagel PS, Warltier DC. Negative inotropic effects of propofol as evaluated by the regional preload recruitable stroke work relationship in chronically instrumented dogs. Anesthesiology 1993;78:100-8.
11. Robinson BJ, Ebert TJ, O'Brien TJ, et al. Mechanisms whereby propofol mediates peripheral vasodilation in humans: sympathoinhibition or direct vascular relaxation? Anesthesiology 1997;86:64-72.
12. Huang YF, Upton RN, Rutten AJ, Runciman WB. IV bolus administration of subconvulsive doses of lignocaine to conscious sheep: effects on circulatory function. Br J Anaesth 1992;69:368-74.
13. Runciman WB, Ilsley A, Mather LE, et al. A sheep preparation for studying interactions between blood flow and drug disposition. Br J Anaesth 1984;56:1015-27.
14. Runciman WB, Ludbrook GL. Monitoring. In: Nimmo WS, Rowbotham DJ, Smith G, eds. Anaesthesia. Oxford: Blackwell Scientific Publications, 1993:704-39.
15. Mather L, Selby D, Runciman W, McLean C. Propofol: assay and regional mass balance in the sheep. Xenobiotica 1989;19:1337-47.
16. Ludbrook GL, Upton RN, Grant C, Gray EC. Cerebral effects of propofol following bolus administration in sheep. Anaesth Intensive Care 1996;24:26-31.
17. Ihaka R, Gentleman R. R: a language for data analysis and graphics. J Comput Graphical Stat 1996;5:299-314.
18. Zheng D, Upton RN, Martinez AM, et al. The influence of the bolus injection rate of propofol on its cardiovascular effects and peak blood concentrations in sheep. Anesth Analg 1998;86:1109-15.
19. Davidson DM, Covell JW, Malloch CI, Ross JJ. Factors influencing indices of left ventricle contractility in the conscious dog. Cardiovasc Res 1974;8:299-312.
20. Hettrick DA, Pagel PS, Warltier DC. Alterations in canine left ventricular-arterial coupling and mechanical efficiency produced by propofol. Anesthesiology 1997;86:1088-93.
21. Marano G, Formigari R, Grigioni M, Vergari A. Effects of isoflurane versus halothane on myocardial contractility in rabbits: assessment with transthoracic two-dimensional echocardiography. Lab Anim 1997;31:144-50.
22. Ismail EF, Kim S-J, Salem MR, Crystal GJ. Direct effects of propofol on myocardial contractility in in situ canine hearts. Anesthesiology 1992;77:964-72.
23. Belo SE, Kolesar R, Mazer CD. Intracoronary propofol does not decrease myocardial contractile function in the dog. Can J Anaesth 1994;41:43-9.
24. Huang YF, Upton RN, Gray EC, et al. The effects of short intravenous infusions of thiopentone on myocardial function, blood flow and oxygen consumption in sheep. Anaesth Intensive Care 1997;25:627-33.
25. Wallerstedt SM, Bodelsson M. Effect of propofol on isolated human omental arteries and veins. Br J Anaesth 1997;78:296-300.
26. Kamitani K, Yamazaki M, Yukitaka M, et al. Effects of propofol on isolated rabbit mesenteric arteries and veins. Br J Anaesth 1995;75:457-61.
27. Azari DM, Cork RC. Comparative myocardial depressive effects of propofol and thiopental. Anesth Analg 1993;77:324-9.
28. Suzer O, Suzer A, Aykac Z, Ozuner Z. Direct cardiac effects in isolated perfused rat hearts measured at increasing concentrations of morphine, alfentanil, fentanyl, ketamine, etomidate, thiopentone midazolam and propofol. Eur J Anaesthesiol 1998;15:480-5.
29. Gelissen HP, Epema AH, Henning RH, et al. Inotropic effects of propofol, thiopental, midazolam, etomidate, and ketamine on isolated human atrial muscle. Anesthesiology 1996;84:397-403.
30. Mouren S, Baron JF, Albo C, et al. Effects of propofol and thiopental on coronary blood flow and myocardial performance in an isolated rabbit heart. Anesthesiology 1994;80:634-41.