Inotropic effects of propofol, thiopental, midazolam, etomidate, and ketamine on isolated human atrial muscle

Anesthesiology

Volumn 84, Issue 2, 1996, Pages 397-403

  Gelissen, Harry P M M ^a   Epema, Anne H ^a,b   Henning, Robert H ^a   Krijnen, H John ^a   Hennis, Pim J ^a   Den Hertog, Adriaan ^a  

^a Department of Anesthesiology ^*

^b UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

Anesthetics, intravenous: etomidate; ketamine; midazolam; propofol; thiopental; Heart, atria: human; isometric contraction; inotropic effect

Indexed keywords

ETOMIDATE; INTRALIPID; KETAMINE; MIDAZOLAM; PROPOFOL; PROPYLENE GLYCOL; THIOPENTAL;

ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; HEART ATRIUM CONTRACTILITY; HUMAN; HUMAN TISSUE; INOTROPISM; INTRAVENOUS ANESTHESIA; MUSCLE FORCE; MUSCLE ISOMETRIC CONTRACTION; PRIORITY JOURNAL;

ANESTHETICS, INTRAVENOUS; ATRIAL FUNCTION; DEPRESSION, CHEMICAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ETOMIDATE; HEART ATRIA; HUMANS; ISOMETRIC CONTRACTION; KETAMINE; MIDAZOLAM; MYOCARDIAL CONTRACTION; PROPOFOL; STIMULATION, CHEMICAL; THIOPENTAL;

EID: 0030062684     PISSN: 00033022     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000542-199602000-00019     Document Type: Article

References (46)

1. Al-Khudhairi D, Whitwam JG, Chakrabarti MK, Askitopoulou H, Grundy EM, Powrie S: Hemodynamic effects of midazolam and thiopentone during induction of anaesthesia for coronary artery surgery. Br J Anaesth 1982; 54:831-5
2. Grounds RM, Twigley AJ, Carli F, Whitwam JG, Morgan M: The hemodynamic effects of intravenous induction: Comparison of the effects of thiopentone and propofol. Anesthesia 1985; 40:735-40
3. Todd MM, Drummond JC, Hoi Sang U: The hemodynamic consequences of high dose thiopental anesthesia. Anesth Analg 1985; 64:681-7
4. Harris CE, Murray AM, Anderson JM, Grounds RM, Morgan M: Effects of thiopentone, etomidate and propofol on the hemodynamic response to tracheal intubation Anesthesia 1988; 43:32-6
5. Azari DM, Cork RC: Comparative myocardial depressive effects of propofol and thiopental. Anesth Analg 1993; 77:324-9
6. Azuma M, Matsumura C, Kemmotsu O: Inotropic and electrophysiologic effects of propofol and thiamylal in isolated papillary muscles of guinea pig and the rat. Anesth Analg 1993; 77:557-63
7. Riou B, Besse S, Lecarpentier Y, Viars P: In vitro effects of propofol on rat myocardium. ANESTHESIOLOGY 1992; 76:609-16
8. Cook DJ, Housmans PR: Mechanism of the negative inotropic effect of propofol in isolated ferret ventricular myocardium. ANESTHESIOLOGY 1994; 80:859-71
9. Frankl WS, Poole-Wilson PA: Effects of thiopental on tension development, action potential, and exchange of calcium and potassium in rabbit ventricular myocardium. J Cardiovasc Pharmacol 1981; 3:554-65
10. Komai H, Rusy BF: Differences in the myocardial depressant action of thiopental and halothane. Anesth Analg 1984; 63:313-8
11. Park WK, Lynch C III: Propofol and thiopental depression of myocardial contractility. Anesth Analg 1992; 74:395-405
12. Housmans PR, Turkan Kudsioglu S, Bingham J: Mechanism of the negative inotropic effect of thiopental in isolated ferret ventricular myocardium. ANESTHESIOLOGY 1995; 82:436-50
13. Komai H, Dewitt DE and Rusy B: Negative inotropic effects of etomidate in rabbit papillary muscle. Anesth Analg 1985; 64:400-4
14. Mattheussen M, Housmans PR: Mechanism of the direct, negative inotropic effect of etomidate in isolated ferret ventricular myocardium. ANESTHESIOLOGY 1993; 79:1284-95
15. Rusy BF, Amuzu JK, Bosscher HA, Redon D, Komai H: Negative inotropic effects of ketamine in rabbit ventricular muscle. Anesth Analg 1990; 71:275-8
16. Endou M, Hattori Y, Nakaya H, Gotoh Y, Kanno M: Electrophysiological mechanisms responsible for inotropic responses to ketamine in guinea pig and rat myocardium. ANESTHESIOLOGY 1992; 76:409-18
17. Kongsayreepong S, Cook DJ, Housmans PR: Mechanism of the direct, negative inotropic effect of ketamine in isolated ferret and frog ventricular myocardium. ANESTHESIOLOGY 1993; 79:313-22
18. Riou B, Lecarpentier Y, Viars P: Effects of etomidate on the cardiac papillary muscle of normal hamsters and those with cardiomyopathy. ANESTHESIOLOGY 1993; 78:83-90
19. Riou B, Lecarpentier Y, Viars P: Inotropic effect of ketamine on rat cardiac papillary muscle. ANESTHESIOLOGY 1989; 71:116-25
20. Cook DJ, Carton EG, Housmans PR: Mechanism of the positive inotropic effect of ketamine in isolated ferret ventricular papillary muscle. ANESTHESIOLOGY 1991; 74:880-8
21. Punt NC, Van Eekeren J, Van Amsterdam FTM, Zaagsma J, Den Hertog A: Dual action of D-cis-diltiazem on calcium entry in guinea pig papillary muscle cells. Eur J Pharmacol 1988; 151:347-8
22. Riou B, Lejay M, Lecarpentier Y, Viars P: Myocardial effects of propofol in hamsters with hypertrophic cardiomyopathy. ANESTHESIOLOGY 1995; 82:566-73
23. Ismail EF, Kim SJ, Salem MR, Crystal GJ: Direct effects of propofol on myocardial contractility in situ canine hearts. ANESTHESIOLOGY 1992; 77:964-72
24. Shafer A, Doze VA, Shafer SL, White PF: Pharmacokinetics and pharmacodynamics of propofol infusions during general anesthesia. ANESTHESIOLOGY 1988; 69:348-456
25. Wood M: Plasma binding and limitation of drug access to site of action (editorial). ANESTHESIOLOGY 1991; 75:721-3
26. Mulier JP, Wouters PF, Van Aken H, Van der Meersch E: Cardiodynamic effects of propofol in comparison with thiopental: Assessment with a transoesophagial echocardiographic approach. Anest Analg 1991; 72:28-35
27. Claeys MA, Gepts E, Camu F: Hemodynamic changes during anaesthesia induced and maintained with propofol. Br J Anaesth 1988; 60:3-9
28. Effendi H, Versprille A, Wise ME: The negative inotropic effect of barbiturates on the heart of newborn and adult guinea pigs. Arch Int Pharmacodyn Ther 1973; 209:127-43
29. Burch PG, Stanski DR: The role of metabolism and protein binding in thiopental anesthesia. ANESTHESIOLOGY 1983; 58:146-52.
30. Hung OR, Varvel JR, Shafer SL, Stanski DR: Thiopental pharmacodynamics: 2. Quantitation of clinical and electroencephalographic depth of anesthesia. ANESTHESIOLOGY 1992; 77:237-44
31. Seltzer JL, Gerson JI, Allen FB Comparison of the cardiovascular effects of bolus v. incremental administration of thiopetone. Br J Anaesth 1980; 52:527-30
32. Reves JG, Kissin I, Fournier S: Negative inotropic effects of midazolam. ANESTHESIOLOGY 1984; 60:517-8
33. Persson P, Nilsson A, Hartvig P, Tamsen A: Pharmacokinetics of midazolam in total IV anaesthesia. Br J Anaesth 1987; 59:549-56
34. Schulte-Sasse U, Hess W, Tarnow J: Hemodynamic responses to induction of anaesthesia using midazolam in cardiac surgical patients. Br J Anaesth 1982; 54:1053-8
35. Kissin I, Motomura S, Aultman DF, Reves JG: Inotropic and anesthetic potencies of etomidate and thiopental in dogs. Anesth Analg 1983; 62:961-5
36. Riou B, Lecarpentier Y, Chemia D, Viars P: In vitro effects of etomidate on intrinsic myocardial contractility in the rat. ANESTHESIOLOGY 1990; 72:330-40
37. Van Hamme MJ, Ghoneim MM, Ambre JJ: Pharmacokinetics of etomidate, a new intravenous anesthetic. ANESTHESIOLOGY 1978; 49: 274-7
38. Kettler D, Sonntag H, Donath U: Haemodynamics, myocardial mechanics, oxygen requirement, and oxygenation of the human heart during induction of anaesthesia with etomidate. Anaesthesist 1974; 23:116-21
39. Brückner JB, Gethman JW, Patschke D, Tarnow J, Weymar A: Investigations into the effect of etomidate on the human circulation. Anaesthesist 1974; 23:322-30
40. Gooding JM, Corssen G: Effect of etomidate on the cardiovascular system. Anesth Analg 1977; 56:717-9
41. Riou B, Viars P, Lecarpentier Y: Effects of ketamine on the cardiac papillary muscle of normal hamsters and those with cardiomyopathy. ANESTHESIOLOGY 1990; 73:910-8
42. Idvall J, Ahlgren I, Aronsen KF, Stenberg P: Ketamine infusions: Pharmacokinetics and clinical effects. Br J Anaesth 1979; 51:1167-72
43. White PF, Way WL, Trevor AJ: Ketamine - its pharmacology and therapeutic uses. ANESTHESIOLOGY 1982; 56:119-36
44. Ivankovich AD, Miletich DJ, Reichmann C, Albrecht RF, Zahed B: Cardiovascular effects of centrally administered ketamine in goats. Anesth Analg 1974; 53:924-31
45. Bidwal AV, Stanley TH, Graves CL: The effects of ketamine on cardiovascular dynamics during halothane and enflurane anesthesia. Anesth Analg 1975; 54:588-92
46. Courtney KR: Significance of bicarbonate for antiarrhythmic drug action. J Mol Cell Cardiol 1981; 13:1031-4