The role of the protein core in the inhibitory power of the classic serine protease inhibitor, chymotrypsin inhibitor 2

Biochemistry

Volumn 42, Issue 21, 2003, Pages 6484-6492

  Radisky, Evette S ^a   King, David S ^a   Kwan, Gene ^a,b   Koshland Jr , Daniel E ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL BONDS; CRYSTAL STRUCTURE; ENZYME INHIBITION; HYDROLYSIS; MUTAGENESIS; SUBSTRATES;

SYNTHETIC CYCLIC PEPTIDES;

PROTEINS;

CHYMOTRYPSIN INHIBITOR; CORE PROTEIN; GLUTAMIC ACID; METHIONINE; SERINE PROTEINASE; SUBTILISIN;

ARTICLE; CHEMICAL ANALYSIS; CHEMICAL BINDING; COMPLEX FORMATION; CRYSTAL STRUCTURE; ENZYME BINDING; ENZYME SPECIFICITY; GENE DELETION; GENE IDENTIFICATION; HYDROLYSIS; PRIORITY JOURNAL; PROTEIN STRUCTURE; PROTEIN SYNTHESIS; SEQUENCE ANALYSIS;

BACILLUS SUBTILIS; DOSE-RESPONSE RELATIONSHIP, DRUG; ESCHERICHIA COLI; GENE DELETION; HYDROGEN BONDING; HYDROLYSIS; KINETICS; MODELS, MOLECULAR; MUTATION; PEPTIDES; PLANT PROTEINS; PROTEIN STRUCTURE, TERTIARY; PROTEINS; RECOMBINANT PROTEINS; SERINE PROTEINASE INHIBITORS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; TIME FACTORS;

EID: 0037672714     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi034275d     Document Type: Article

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