Role for the fission yeast RecQ helicase in DNA repair in G2

Molecular and Cellular Biology

Volumn 23, Issue 10, 2003, Pages 3692-3705

  Laursen, Louise V ^a,b   Ampatzidou, Eleni ^b   Andersen, Anni H ^a   Murray, Johanne M ^b  

^a AARHUS UNIVERSITY   (Denmark)

^b UNIVERSITY OF SUSSEX   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

HELICASE; PROTEIN; PROTEIN RHP51; PROTEIN RQH1; PROTEIN TOP3; RAD51 PROTEIN; RECQ HELICASE; UNCLASSIFIED DRUG;

ARTICLE; BLOOM SYNDROME; CELL SYNCHRONIZATION; DNA DAMAGE; DNA REPAIR; ENZYME ACTIVITY; EPISTASIS; GENE DELETION; GENETIC RECOMBINATION; MOLECULAR WEIGHT; NONHUMAN; PRIORITY JOURNAL; PROTEIN FAMILY; ROTHMUND THOMSON SYNDROME; SCHIZOSACCHAROMYCES POMBE; ULTRAVIOLET RADIATION; WERNER SYNDROME; YEAST;

ADENOSINE TRIPHOSPHATASES; ALLELES; BLOTTING, WESTERN; CLONING, MOLECULAR; DNA DAMAGE; DNA HELICASES; DNA REPAIR; DNA TOPOISOMERASES, TYPE I; DNA, COMPLEMENTARY; DOSE-RESPONSE RELATIONSHIP, RADIATION; G2 PHASE; MODELS, BIOLOGICAL; MUTATION; POLYMERASE CHAIN REACTION; PRECIPITIN TESTS; PROTEIN BIOSYNTHESIS; RECOMBINATION, GENETIC; RECQ HELICASES; SCHIZOSACCHAROMYCES; SCHIZOSACCHAROMYCES POMBE PROTEINS; SUBCELLULAR FRACTIONS; TIME FACTORS; ULTRAVIOLET RAYS;

SACCHAROMYCES; SACCHAROMYCES CEREVISIAE; SCHIZOSACCHAROMYCES; SCHIZOSACCHAROMYCES POMBE;

EID: 0037627346     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.23.10.3692-3705.2003     Document Type: Article

References (55)

1. Bahler, J., J. Q. Wu, M. S. Longtine, N. G. Shah, A. McKenzie, A. B. Steever, A. Wach, P. Philippsen, and J. R. Pringle. 1998. Heterologous modules for efficient and versatile PCR-based gene targeting in Schizosaccharomyces pombe. Yeast 14:943-951.
2. Barbet, N. C., and A. M. Carr. 1993. Fission yeast weel protein kinase is not required for DNA damage-dependent mitotic arrest. Nature 364:824-827.
3. Bennett, R., M. Noirot-Gros, and J. Wang. 2000. Interaction between yeast sgs1 helicase and DNA topoisomerase III. J. Biol. Chem. 275:26898-26905.
4. Bennett, R., J. Sharp, and J. Wang. 1998. Purification and characterization of the Sgs1 DNA helicase activity of Saccharomyces cerevisiae. J. Biol. Chem. 273:9644-9650.
5. Bischof, O., S.-H. Kim, J. Irving, S. Beresten, N. A. Ellis, and J. Campisi. 2001. Regulation and localization of the Bloom syndrome protein in response to DNA damage. J. Cell Biol. 153:367-380.
6. Broomfield, S., T. Hryciw, and W. Xiao. 2001. DNA postreplication repair and mutagenesis in Saccharomyces cerevisiae. Mutat. Res. 486:167-184.
7. Carr, A. M. 2002. DNA structure dependent checkpoints as regulators of DNA repair. DNA Repair 1:983-994.
8. Caspari, T., M. Dahlen, G. Kanter-Smoler, H. D. Lindsay, K. Hofmann, K. Papadimitriou, P. Sunnerhagen, and A. M. Carr. 2000. Characterization of Schizosaccharomyces pombe Hus1: a PCNA-related protein that associates with Rad1 and Rad9. Mol. Cell. Biol. 20:1254-1262.
9. Caspari, T., J. M. Murray, and A. M. Carr. 2002. Cdc2-cyclin B kinase activity links Crb2 and Rqh1-topoisomerase III. Genes Dev. 16:1195-1208.
10. Chakraverty, R. K., and I. D. Hickson. 1999. Defending genome integrity during DNA replication: a proposed role for RecQ family helicases. Bioessays 21:286-294.
11. Chakraverty, R. K., J. M. Kearsey, T. J. Oakley, M. Grenon, M. A. de La Torre Ruiz, N. F. Lowndes, and I. D. Hickson. 2001. Topoisomerase III acts upstream of Rad53p in the S-phase DNA damage checkpoint. Mol. Cell. Biol. 21:7150-7162.
12. Christensen, P. U., N. J. Bentley, R. G. Martinho, O. Nielsen, and A. M. Carr. 2000. Mik1 levels accumulate in S phase and may mediate an intrinsic link between S phase and mitosis. Proc. Natl. Acad. Sci. USA 97:2579-2584.
13. Courcelle, J., and P. Hanawalt. 1999. RecQ and RecJ process blocked replication forks prior to the resumption of replication in UV-irradiated Escherichia coli. Mol. Gen. Genet. 262:543-551.
14. Cox, M. M. 2001. Historical overview: searching for replication help in all of the rec places. Proc. Natl. Acad. Sci. USA 98:8173-8180.
15. Craven, R. A., D. J. F. Griffiths, K. S. Sheldrick, R. E. Randall, I. M. Hagan, and A. M. Carr. 1998. Vectors for the expression of tagged proteins in Schizosaccharomyces pombe. Gene 221:59-68.
16. DiGate, R. J., and K. J. Marians. 1992. Escherichia coli topoisomerase III-catalyzed cleavage of RNA. J. Biol. Chem. 267:20532-20535.
17. Doe, C. L., J. Dixon, F. Osman, and M. C. Whitby. 2000. Partial suppression of the fission yeast rqh1(-) phenotype by expression of a bacterial Holliday junction resolvase. EMBO J. 19:2751-2762.
18. Edwards, R. J., and A. M. Carr. 1997. Analysis of radiation-sensitive mutants of fission yeast. Methods Enzymol. 283:471-494.
19. Fricke, W., V. Kaliraman, and S. Brill. 2001. Mapping the DNA topoisomerase III binding domain of the Sgs1 DNA helicase. J. Biol. Chem. 276:8848-8855.
20. Gangloff, S., J. P. McDonald, C. Bendixen, L. Arthur, and R. Rothstein. 1994. The yeast type I topoisomerase Top3 interacts with Sgs1, a DNA helicase homolog: a potential eukaryotic reverse gyrase. Mol. Cell. Biol. 14:8391-8398.
21. German, J., R. Archibald, and D. Bloom. 1965. Chromosomal breakage in a rare and probably genetically determined syndrome of man. Science 148:506-507.
22. Goodwin, A., S.-W. Wang, T. Toda, C. Norbury, and I. D. Hickson. 1999. Topoisomerase III is essential for accurate nuclear division in Schizosaccharomyces pombe. Nucleic Acids Res. 27:4050-4058.
23. Haaf, T., E. I. Golub, G. Reddy, C. M. Radding, and D. C. Ward. 1995. Nuclear foci of mammalian Rad51 recombination protein in somatic cells after DNA damage and its localization in synaptonemal complexes. Proc. Natl. Acad. Sci. USA 92:2298-2302.
24. Harmon, F., and S. Kowalczykowski. 1998. RecQ helicase, in concert with RecA and SSB proteins, initiates and disrupts DNA recombination. Genes Dev. 12:1134-1144.
25. Harmon, F. G., R. J. DiGate, and S. C. Kowalczykowski. 1999. RecQ helicase and topoisomerase III comprise a novel DNA strand passage function: a conserved mechanism for control of DNA recombination. Mol. Cell 3:611-620.
26. Johnson, F. B., D. B. Lombard, N. F. Neff, M. A. Mastrangelo, W. Dewolf, N. A. Ellis, R. A. Marciniak, Y. Yin, R. Jaenisch, and L. Guarente. 2000. Association of the Bloom syndrome protein with topoisomerase IIIalpha in somatic and meiotic cells. Cancer Res. 60:1162-1167.
27. Kaliraman, V., J. R. Mullen, W. M. Fricke, S. A. Bastin-Shanower, and S. J. Brill. 2001. Functional overlap between Sgs1-Top3 and the Mms4-Mus81 endonuclease. Genes Dev. 15:2730-3740.
28. Karow, J., R. Chakraverty, and I. Hickson. 1997. The Bloom's syndrome gene product is a 3′-5′ DNA helicase. J. Biol. Chem. 272:30611-30614.
29. Karow, J., R. Newman, P. Freemont, and I. Hickson. 1999. Oligomeric ring structure of the Bloom's syndrome helicase. Curr. Biol. 9:597-600.
30. Kaur, B., A. M. Avery, and P. W. Doetsch. 1998. Expression, purification, and characterization of ultraviolet DNA endonuclease from Schizosaccharomyces pombe. Biochemistry 37:11599-11604.
31. Kitao, S., N. M. Lindor, M. Shiratori, Y. Furuichi, and A. Shimamoto. 1999. Rothmund-Thomson syndrome responsible gene, RECQL4: genomic structure and products. Genomics 61:268-276.
32. Liu, Y., and N. Maizels. 2000. Coordinated response of mammalian Rad51 and Rad52 to DNA damage. EMBO Rep. 1:85-90.
33. Maftahi, M., C. S. Han, L. D. Langston, J. C. Hope, N. Zigouras, and G. A. Freyer. 1999. The top3(+) gene is essential in Schizosaccharomyces pombe and the lethality associated with its loss is caused by Rad12 helicase activity. Nucleic Acids Res, 27:4715-4724.
34. Marians, K. J. 2000. Replication and recombination intersect. Curr. Opin. Genet. Dev. 10:151-156.
35. McCready, S. J., F. Osman, and A. Yasui. 2000. Repair of UV damage in the fission yeast Schizosaccharomyces pombe. Mutat. Res. 451:197-210.
36. Michel, B., M.-J. Flores, E. Viguera, G. Grompone, M. Seigneur, and V. Bidnenko. 2001. Rescue of arrested replication forks by homologous recombination. Proc. Natl. Acad. Sci. USA 98:8181-8188.
37. Mohaghegh, P., and I. D. Hickson. 2001. DNA helicase deficiencies associated with cancer predisposition and premature aging disorders. Hum. Mol. Genet. 10:741-746.
38. Moreno, S., A. Klar, and P. Nurse. 1991. Molecular genetic analysis of fission yeast Schizosaccharomyces pombe. Methods Enzymol. 194:795-826.
39. Muris, D. F. R., K. Vreeden, A. M. Carr, B. C. Broughton, A. R. Lehmann, P. H. M. Lohman, and A. Pastink. 1993. Cloning the RAD51 homologue of Schizosaccharomyces pombe. Nucleic Acids Res. 21:4586-4591.
40. +, a gene involved in the repair of radiation damage and replication fidelity. J. Cell Sci. 109:73-81.
41. + genes. Curr. Genet. 31:248-254.
42. Murray, J. M., H. D. Lindsay, C. A. Munday, and A. M. Carr. 1997. Role of Schizosaccharomyces pombe RecQ homolog, recombination, and checkpoint genes in UV damage tolerance. Mol. Cell. Biol. 17:6868-6875.
43. Onodera, R., M. Seki, A. Ui, Y. Satoh, A. Miyajima, F. Onoda, and T. Enomoto. 2002. Functional and physical interaction between Sgs1 and Top3 and Sgs1-independent function of Top3 in DNA recombination repair. Genes Genet. Syst. 77:11-21.
44. Paques, F., and J. E. Haber. 1999. Multiple pathways of double-strand-break-induced recombination in Saccharomyces cerevisiae. Microbiol. Mol. Biol. Rev. 63:349-404.
45. +, a fission yeast gene related to the Bloom's and Werner's syndrome genes, is required for reversible S phase arrest. EMBO J. 16:2682-2692.
46. Tashiro, S., N. Kotomura, A. Shinohara, K. Tanaka, K. Ueda, and N. Kamada. 1996. S phase specific formation of the human Rad51 protein nuclear foci in lymphocytes. Oncogene 12:2165-2170.
47. Tashiro, S., J. Walter, A. Shinohara, N. Kamada, and T. Cremer. 2000. Rad51 accumulation at sites of DNA damage and in postreplicative chromatin. J. Cell Biol. 150:283-291.
48. Verkade, H., T. Teli, L. Laursen, J. Murray, and M. O'Connell. 2001. A homologue of the Rad18 postreplication repair gene is required for DNA damage responses throughout the fission yeast cell cycle. Mol. Genet. Genomics 265:993-1003.
49. Watt, P. M., E. J. Louis, R. H. Borts, and I. D. Hickson. 1995. Sgs1: a eukaryotic homolog of E. coli RecQ that interacts with topoisomerase II in vivo and is required for faithful chromosome segregation. Cell 81:253-260.
50. Wu, L., S. Davies, P. North, H. Goulaouic, J. Riou, H. Turley, K. Gatter, and I. Hickson. 2000. The Bloom's syndrome gene product interacts with topoisomerase III. J. Biol. Chem. 275:9636-9644.
51. Wu, L., S. L. Davies, N. C. Levitt, and 1. D. Hickson. 2001. Potential role for the BLM helicase in recombinational repair via a conserved interaction with RAD51. J. Biol. Chem. 276:19375-19381.
52. Wu, L., and I. D. Hickson. 2002. RecQ helicases and cellular responses to DNA damage. Mutat. Res. 509:35-47.
53. Yasui, A., and S. J. McCready. 1998. Alternative repair pathways for UV-induced DNA damage. Bioessays 20:291-297.
54. Yonemasu, R., S. McCready, J. M. Murray, F. Osman, M. Takao, K. Yamamoto, A. R. Lehmann, and A. Yasui. 1997. Characterization of the alternative excision repair pathway of UV-damaged DNA in Schizosaccharomyces pombe. Nucleic Acids Res. 25:1553-1558.
55. Yu, C.-E., J. Oshima, Y.-H. Fu, E. M. Wijsman, F. Hisama, R. Alisch, S. Matthews, J. Nakura, T. Miki, S. Ouasi, G. M. Martin, J. Mulligan, and G. D. Schellenberg. 1996. Positional cloning of the Werner's syndrome gene. Science 272:258-262.