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Volumn 284, Issue 6 53-6, 2003, Pages

Neurotensin stimulates IL-8 expression in human colonic epithelial cells through Rho GTPase-mediated NF-κB pathways

Author keywords

Gene regulation; Inflammation; Neuropeptide; Signal transduction

Indexed keywords

GUANOSINE TRIPHOSPHATASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 8; MITOGEN ACTIVATED PROTEIN KINASE; NEUROTENSIN; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; SYNAPTOPHYSIN;

EID: 0037598638     PISSN: 03636143     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpcell.00328.2002     Document Type: Article
Times cited : (77)

References (48)
  • 1
    • 0022447526 scopus 로고
    • Activation of phosphatidylinositol turnover by neurotensin receptors in the human colonic adenocarcinoma cell line HT 29
    • Amar S, Kitabgi P, and Vincent JP. Activation of phosphatidylinositol turnover by neurotensin receptors in the human colonic adenocarcinoma cell line HT29. FEBS Lett 201: 31-36, 1986.
    • (1986) FEBS Lett , vol.201 , pp. 31-36
    • Amar, S.1    Kitabgi, P.2    Vincent, J.P.3
  • 3
    • 0024848274 scopus 로고
    • Neurotensin stimulates inositol trisphosphate-mediated calcium mobilization but not protein kinase C activation in HT29 cells. Involvement of a G-protein
    • Bozou JC, Rochet N, Magnaldo I, Vincent JP, and Kitabgi P. Neurotensin stimulates inositol trisphosphate-mediated calcium mobilization but not protein kinase C activation in HT29 cells. Involvement of a G-protein. Biochem J 264: 871-878, 1989.
    • (1989) Biochem J , vol.264 , pp. 871-878
    • Bozou, J.C.1    Rochet, N.2    Magnaldo, I.3    Vincent, J.P.4    Kitabgi, P.5
  • 4
    • 0035854826 scopus 로고    scopus 로고
    • Dbl and the Rho GTPases activate NFκB by IκB kinase (IKK)-dependent and IKK-independent pathways
    • Cammarano MS and Minden A. Dbl and the Rho GTPases activate NFκB by IκB kinase (IKK)-dependent and IKK-independent pathways. J Biol Chem 276: 25876-25882, 2001.
    • (2001) J Biol Chem , vol.276 , pp. 25876-25882
    • Cammarano, M.S.1    Minden, A.2
  • 5
    • 0017114234 scopus 로고
    • Characterization of radioimmunoassayable neurotensin in the rat. Its differential distribution in the central nervous system, small intestine, and stomach
    • Carraway R and Leeman SE. Characterization of radioimmunoassayable neurotensin in the rat. Its differential distribution in the central nervous system, small intestine, and stomach. J Biol Chem 251: 7045-7052, 1976.
    • (1976) J Biol Chem , vol.251 , pp. 7045-7052
    • Carraway, R.1    Leeman, S.E.2
  • 6
    • 0015821329 scopus 로고
    • The isolation of a new hypotensive peptide, neurotensin, from bovine hypothalami
    • Carraway R and Leeman SE. The isolation of a new hypotensive peptide, neurotensin, from bovine hypothalami. J Biol Chem 248: 6854-6861, 1973.
    • (1973) J Biol Chem , vol.248 , pp. 6854-6861
    • Carraway, R.1    Leeman, S.E.2
  • 7
    • 0032698069 scopus 로고    scopus 로고
    • The p38 mitogen- activated protein kinase is required for NF-κB-dependent gene expression. The role of TATA-binding protein (TBP)
    • Carter AB, Knudtson KL, Monick MM, and Hunninghake GW. The p38 mitogen- activated protein kinase is required for NF-κB-dependent gene expression. The role of TATA-binding protein (TBP). J Biol Chem 274: 30858-30863, 1999.
    • (1999) J Biol Chem , vol.274 , pp. 30858-30863
    • Carter, A.B.1    Knudtson, K.L.2    Monick, M.M.3    Hunninghake, G.W.4
  • 11
    • 0035004343 scopus 로고    scopus 로고
    • Pathogenicity island-dependent activation of Rho GTPases Rac 1 and Cdc42 in Helicobacter pylori infection
    • Churin Y, Kardalinou E, Meyer TF, and Naumann M. Pathogenicity island-dependent activation of Rho GTPases Rac1 and Cdc42 in Helicobacter pylori infection. Mol Microbiol 40: 815-823, 2001.
    • (2001) Mol Microbiol , vol.40 , pp. 815-823
    • Churin, Y.1    Kardalinou, E.2    Meyer, T.F.3    Naumann, M.4
  • 12
    • 0029055812 scopus 로고
    • The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway
    • Coso OA, Chiariello M, Yu JC, Teramoto H, Crespo P, Xu N, Miki T, and Gutkind JS. The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway. Cell 81: 1137-1146, 1995.
    • (1995) Cell , vol.81 , pp. 1137-1146
    • Coso, O.A.1    Chiariello, M.2    Yu, J.C.3    Teramoto, H.4    Crespo, P.5    Xu, N.6    Miki, T.7    Gutkind, J.S.8
  • 13
    • 0034708354 scopus 로고    scopus 로고
    • Neurotensin-mediated activation of MAPK pathways and AP-1 binding in the human pancreatic cancer cell line, MIA PaCa-2
    • Ehlers RA, Zhang Y, Hellmich MR, and Evers BM. Neurotensin-mediated activation of MAPK pathways and AP-1 binding in the human pancreatic cancer cell line, MIA PaCa-2. Biochem Biophys Res Commun 269: 704-708, 2000.
    • (2000) Biochem Biophys Res Commun , vol.269 , pp. 704-708
    • Ehlers, R.A.1    Zhang, Y.2    Hellmich, M.R.3    Evers, B.M.4
  • 15
    • 0037069690 scopus 로고    scopus 로고
    • Rho GTPases in cell biology
    • Etienne-Manneville S and Hall A. Rho GTPases in cell biology. Nature 420: 629-635, 2002.
    • (2002) Nature , vol.420 , pp. 629-635
    • Etienne-Manneville, S.1    Hall, A.2
  • 17
    • 0034671936 scopus 로고    scopus 로고
    • p21-activated kinase 1 activates the nuclear factor κB (NF-κB)-inducing kinase-IκB kinases NF-κB pathway and proinflammatory cytokines in Helicobacter pylori infection
    • Foryst-Ludwig A and Naumann M. p21-activated kinase 1 activates the nuclear factor κB (NF-κB)-inducing kinase-IκB kinases NF-κB pathway and proinflammatory cytokines in Helicobacter pylori infection. J Biol Chem 275: 39779-39785, 2000.
    • (2000) J Biol Chem , vol.275 , pp. 39779-39785
    • Foryst-Ludwig, A.1    Naumann, M.2
  • 18
    • 0032559362 scopus 로고    scopus 로고
    • Rho GTPases and the actin cytoskeleton
    • Hall A. Rho GTPases and the actin cytoskeleton. Science 279: 509-514, 1998.
    • (1998) Science , vol.279 , pp. 509-514
    • Hall, A.1
  • 19
    • 0034729916 scopus 로고    scopus 로고
    • Rho GTPases: Molecular switches that control the organization and dynamics of the actin cytoskeleton
    • Hall A and Nobes CD. Rho GTPases: molecular switches that control the organization and dynamics of the actin cytoskeleton. Philos Trans R Soc Lond B Biol Sci 355: 965-970, 2000.
    • (2000) Philos Trans R Soc Lond B Biol Sci , vol.355 , pp. 965-970
    • Hall, A.1    Nobes, C.D.2
  • 20
    • 0029015774 scopus 로고
    • The Rho family GTPases RhoA, Rac 1, and CDC42Hs regulate transcriptional activation by SRF
    • Hill CS, Wynne J, and Treisman R. The Rho family GTPases RhoA, Rac1, and CDC42Hs regulate transcriptional activation by SRF. Cell 81: 1159-11570, 1995.
    • (1995) Cell , vol.81 , pp. 1159-11570
    • Hill, C.S.1    Wynne, J.2    Treisman, R.3
  • 22
    • 0035798543 scopus 로고    scopus 로고
    • Chemoattractant-stimulated NF-κB activation is dependent on the low molecular weight GTPase RhoA
    • Huang S, Chen LY, Zuraw BL, Ye RD, and Pan ZK. Chemoattractant-stimulated NF-κB activation is dependent on the low molecular weight GTPase RhoA. J Biol Chem 276: 40977-40981, 2001.
    • (2001) J Biol Chem , vol.276 , pp. 40977-40981
    • Huang, S.1    Chen, L.Y.2    Zuraw, B.L.3    Ye, R.D.4    Pan, Z.K.5
  • 23
    • 0034602967 scopus 로고    scopus 로고
    • Rac1 regulates interleukin 1-induced nuclear factor κB activation in an inhibitory protein κBαindependent manner by enhancing the ability of the p 65 subunit to transactivate gene expression
    • Jefferies CA and O'Neill LA. Rac1 regulates interleukin 1-induced nuclear factor κB activation in an inhibitory protein κBαindependent manner by enhancing the ability of the p65 subunit to transactivate gene expression. J Biol Chem 275: 3114-3120, 2000.
    • (2000) J Biol Chem , vol.275 , pp. 3114-3120
    • Jefferies, C.A.1    O'Neill, L.A.2
  • 26
    • 0032516846 scopus 로고    scopus 로고
    • Rho GTPases
    • Mackay DJ and Hall A. Rho GTPases. J Biol Chem 273: 20685-20688, 1998.
    • (1998) J Biol Chem , vol.273 , pp. 20685-20688
    • Mackay, D.J.1    Hall, A.2
  • 27
    • 0033959736 scopus 로고    scopus 로고
    • RAC1/P38 MAPK signaling pathway controls beta1 integrin-induced interleukin-8 production in human natural killer cells
    • Mainiero F, Soriani A, Strippoli R, Jacobelli J, Gismondi A, Piccoli M, Frati L, and Santoni A. RAC1/P38 MAPK signaling pathway controls beta1 integrin-induced interleukin-8 production in human natural killer cells. Immunity 12: 7-16, 2000.
    • (2000) Immunity , vol.12 , pp. 7-16
    • Mainiero, F.1    Soriani, A.2    Strippoli, R.3    Jacobelli, J.4    Gismondi, A.5    Piccoli, M.6    Frati, L.7    Santoni, A.8
  • 28
    • 0032961942 scopus 로고    scopus 로고
    • Neurotensin and a non-peptide neurotensin receptor antagonist control human colon cancer cell growth in cell culture and in cells xenografted into nude mice
    • Maoret JJ, Anini Y, Rouyer-Fessard C, Gully D, and Laburthe M. Neurotensin and a non-peptide neurotensin receptor antagonist control human colon cancer cell growth in cell culture and in cells xenografted into nude mice. Int J Cancer 80: 448-454, 1999.
    • (1999) Int J Cancer , vol.80 , pp. 448-454
    • Maoret, J.J.1    Anini, Y.2    Rouyer-Fessard, C.3    Gully, D.4    Laburthe, M.5
  • 29
    • 0033605654 scopus 로고    scopus 로고
    • Activation of serum response factor by RhoA is mediated by the nuclear factor-κB and C/EBP transcription factors
    • Montaner S, Perona R, Saniger L, and Lacal JC. Activation of serum response factor by RhoA is mediated by the nuclear factor-κB and C/EBP transcription factors. J Biol Chem 274: 8506-8515, 1999.
    • (1999) J Biol Chem , vol.274 , pp. 8506-8515
    • Montaner, S.1    Perona, R.2    Saniger, L.3    Lacal, J.C.4
  • 30
    • 0031597368 scopus 로고    scopus 로고
    • Coordinate regulation of IκB kinases by mitogen-activated protein kinase kinase kinase 1 and NF-κB-inducing kinase
    • Nemoto S, DiDonato JA, and Lin A. Coordinate regulation of IκB kinases by mitogen-activated protein kinase kinase kinase 1 and NF-κB-inducing kinase. Mol Cell Biol 18: 7336-7343, 1998.
    • (1998) Mol Cell Biol , vol.18 , pp. 7336-7343
    • Nemoto, S.1    DiDonato, J.A.2    Lin, A.3
  • 31
    • 0032520791 scopus 로고    scopus 로고
    • Role of the Rho GTPase in bradykinin-stimulated nuclear factor-κB activation and IL-1β gene expression in cultured human epithelial cells
    • Pan ZK, Ye RD, Christiansen SC, Jagels MA, Bokoch GM, and Zuraw BL. Role of the Rho GTPase in bradykinin-stimulated nuclear factor-κB activation and IL-1β gene expression in cultured human epithelial cells. J Immunol 160: 3038-30345, 1998.
    • (1998) J Immunol , vol.160 , pp. 3038-30345
    • Pan, Z.K.1    Ye, R.D.2    Christiansen, S.C.3    Jagels, M.A.4    Bokoch, G.M.5    Zuraw, B.L.6
  • 34
    • 0033081753 scopus 로고    scopus 로고
    • Regulation of the small GTP-binding protein Rho by cell adhesion and the cytoskeleton
    • Ren XD, Kiosses WB, and Schwartz MA. Regulation of the small GTP-binding protein Rho by cell adhesion and the cytoskeleton. EMBO J 18: 578-585, 1999.
    • (1999) EMBO J , vol.18 , pp. 578-585
    • Ren, X.D.1    Kiosses, W.B.2    Schwartz, M.A.3
  • 37
    • 0032174942 scopus 로고    scopus 로고
    • Activation of NFκB in inflammatory bowel disease
    • Schmid RM, Adler G, and Liptay S. Activation of NFκB in inflammatory bowel disease. Gut 43: 587-588, 1998.
    • (1998) Gut , vol.43 , pp. 587-588
    • Schmid, R.M.1    Adler, G.2    Liptay, S.3
  • 38
    • 0032977036 scopus 로고    scopus 로고
    • Rho as a mediator of G protein-coupled receptor signaling
    • Seasholtz TM, Majumdar M, and Brown JH. Rho as a mediator of G protein-coupled receptor signaling. Mol Pharmacol 55: 949-956, 1999.
    • (1999) Mol Pharmacol , vol.55 , pp. 949-956
    • Seasholtz, T.M.1    Majumdar, M.2    Brown, J.H.3
  • 39
    • 0029913510 scopus 로고    scopus 로고
    • Signaling from the small GTP-binding proteins Rac1 and Cdc42 to the c-Jun N-terminal kinase/stress-activated protein kinase pathway. A role for mixed lineage kinase 3/protein-tyrosine kinase 1, a novel member of the mixed lineage kinase family
    • Teramoto H, Coso OA, Miyata H, Igishi T, Miki T, and Gutkind JS. Signaling from the small GTP-binding proteins Rac1 and Cdc42 to the c-Jun N-terminal kinase/stress-activated protein kinase pathway. A role for mixed lineage kinase 3/protein-tyrosine kinase 1, a novel member of the mixed lineage kinase family. J Biol Chem 271: 27225-27228, 1996.
    • (1996) J Biol Chem , vol.271 , pp. 27225-27228
    • Teramoto, H.1    Coso, O.A.2    Miyata, H.3    Igishi, T.4    Miki, T.5    Gutkind, J.S.6
  • 40
    • 0029911520 scopus 로고    scopus 로고
    • The small GTP-binding protein rho activates c-Jun N-terminal kinases/stress-activated protein kinases in human kidney 293T cells. Evidence for a Pak-independent signaling pathway
    • Teramoto H, Crespo P, Coso OA, Igishi T, Xu N, and Gutkind JS. The small GTP-binding protein rho activates c-Jun N-terminal kinases/stress-activated protein kinases in human kidney 293T cells. Evidence for a Pak-independent signaling pathway. J Biol Chem 271: 25731-25734, 1996.
    • (1996) J Biol Chem , vol.271 , pp. 25731-25734
    • Teramoto, H.1    Crespo, P.2    Coso, O.A.3    Igishi, T.4    Xu, N.5    Gutkind, J.S.6
  • 41
    • 0022629104 scopus 로고
    • Neurotensin increases colonic motility
    • Thor K and Rosell S. Neurotensin increases colonic motility. Gastroenterology 90: 27-31, 1986.
    • (1986) Gastroenterology , vol.90 , pp. 27-31
    • Thor, K.1    Rosell, S.2
  • 42
    • 0032488837 scopus 로고    scopus 로고
    • p38 and extracellular signal-regulated kinase mitogen-activated protein kinase pathways are required for nuclear factor-κB p65 transactivation mediated by tumor necrosis factor
    • Vanden Berghe W, Plaisance S, Boone E, De Bosscher K, Schmitz ML, Fiers W, and Haegeman G. p38 and extracellular signal-regulated kinase mitogen-activated protein kinase pathways are required for nuclear factor-κB p65 transactivation mediated by tumor necrosis factor. J Biol Chem 273: 3285-3290, 1998.
    • (1998) J Biol Chem , vol.273 , pp. 3285-3290
    • Vanden Berghe, W.1    Plaisance, S.2    Boone, E.3    De Bosscher, K.4    Schmitz, M.L.5    Fiers, W.6    Haegeman, G.7
  • 44
    • 0024215838 scopus 로고
    • Effect of neurotensin on pancreatic and gastric secretion and growth in rats
    • Wood JG, Hoang HD, Bussjaeger LJ, and Solomon TE. Effect of neurotensin on pancreatic and gastric secretion and growth in rats. Pancreas 3: 332-339, 1988.
    • (1988) Pancreas , vol.3 , pp. 332-339
    • Wood, J.G.1    Hoang, H.D.2    Bussjaeger, L.J.3    Solomon, T.E.4
  • 47
    • 0035976975 scopus 로고    scopus 로고
    • Signal transduction pathways mediating neurotensin-stimulated interleukin-8 expression in human colonocytes
    • Zhao D, Keates AC, Kuhnt-Moore S, Moyer MP, Kelly CP, and Pothoulakis C. Signal transduction pathways mediating neurotensin-stimulated interleukin-8 expression in human colonocytes. J Biol Chem 276: 44464-44471, 2001.
    • (2001) J Biol Chem , vol.276 , pp. 44464-44471
    • Zhao, D.1    Keates, A.C.2    Kuhnt-Moore, S.3    Moyer, M.P.4    Kelly, C.P.5    Pothoulakis, C.6
  • 48
    • 0036901591 scopus 로고    scopus 로고
    • Substance P-stimulated interleukin-8 expression in human colonic epithelial cells involves Rho family small GTPases
    • Zhao D, Kuhnt-Moore S, Zeng H, Pan A, Wu JS, Simeonidis S, Moyer MP, and Pothoulakis C. Substance P-stimulated interleukin-8 expression in human colonic epithelial cells involves Rho family small GTPases. Biochem J 368: 665-672, 2002.
    • (2002) Biochem J , vol.368 , pp. 665-672
    • Zhao, D.1    Kuhnt-Moore, S.2    Zeng, H.3    Pan, A.4    Wu, J.S.5    Simeonidis, S.6    Moyer, M.P.7    Pothoulakis, C.8


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