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Volumn 246, Issue 2, 1999, Pages 451-460

Multimeric α-lactalbumin from human milk induces apoptosis through a direct effect on cell nuclei

Author keywords

Apoptosis; Human milk; Nuclear targeting; Tumor; lactalbumin

Indexed keywords

ALPHA LACTALBUMIN; CALCIUM ION; DNA FRAGMENT;

EID: 0037584357     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1006/excr.1998.4265     Document Type: Article
Times cited : (90)

References (31)
  • 1
    • 0027333347 scopus 로고
    • Programmed cell death, apoptosis and killer genes
    • Schwartz L. M., Osborne B. A. Programmed cell death, apoptosis and killer genes. Immunol. Today. 14:1993;582-590.
    • (1993) Immunol. Today , vol.14 , pp. 582-590
    • Schwartz, L.M.1    Osborne, B.A.2
  • 2
    • 0029891162 scopus 로고    scopus 로고
    • Apoptosis - Molecular mechanisms and biomedical implications
    • McConkey D. J., Zhivotovsky B., Orrenius S. Apoptosis - Molecular mechanisms and biomedical implications. Mol. Aspects Med. 17:1996;1-115.
    • (1996) Mol. Aspects Med. , vol.17 , pp. 1-115
    • McConkey, D.J.1    Zhivotovsky, B.2    Orrenius, S.3
  • 3
    • 0028329172 scopus 로고
    • Apoptosis. Its significance in cancer and cancer therapy
    • Kerr J. F., Winterford C. M., Harmon B. V. Apoptosis. Its significance in cancer and cancer therapy. Cancer. 73:1994;2013-2026.
    • (1994) Cancer , vol.73 , pp. 2013-2026
    • Kerr, J.F.1    Winterford, C.M.2    Harmon, B.V.3
  • 6
    • 0029069295 scopus 로고
    • ICE-like proteases in apoptosis
    • Kumar S. ICE-like proteases in apoptosis. Trends Biochem. Sci. 20:1995;198-202.
    • (1995) Trends Biochem. Sci. , vol.20 , pp. 198-202
    • Kumar, S.1
  • 8
    • 0031888955 scopus 로고    scopus 로고
    • A caspase-activated DNase that degrades DNA during apoptosis and its inhibitor ICAD
    • Enari M., Sakahira H., Yokoyama H., Okawa K., Iwamatsu A., Nagata S. A caspase-activated DNase that degrades DNA during apoptosis and its inhibitor ICAD. Nature. 391:1998;43-50.
    • (1998) Nature , vol.391 , pp. 43-50
    • Enari, M.1    Sakahira, H.2    Yokoyama, H.3    Okawa, K.4    Iwamatsu, A.5    Nagata, S.6
  • 9
    • 0030599449 scopus 로고    scopus 로고
    • Granzyme B/perforin-mediated apoptosis of Jurkat cells results in cleavage of poly(ADP-ribose) polymerase to the 89-kDa apoptotic fragment and less abundant 64-kDa fragment
    • Froelich C. J., Hanna W. L., Poirier G. G., Duriez P. J., D'Amours D., Salvesen G. S., Alnemri E. S., Earnshaw W. C., Shah G. M. Granzyme B/perforin-mediated apoptosis of Jurkat cells results in cleavage of poly(ADP-ribose) polymerase to the 89-kDa apoptotic fragment and less abundant 64-kDa fragment. Biochem Biophys Res Commun. 227:1996;658-665.
    • (1996) Biochem Biophys Res Commun. , vol.227 , pp. 658-665
    • Froelich, C.J.1    Hanna, W.L.2    Poirier, G.G.3    Duriez, P.J.4    D'Amours, D.5    Salvesen, G.S.6    Alnemri, E.S.7    Earnshaw, W.C.8    Shah, G.M.9
  • 10
    • 0032055097 scopus 로고    scopus 로고
    • Granzyme B directly and efficiently cleaves several downstream caspase substrates: Implications for CTL-induced apoptosis
    • Andrade F., Roy S., Nicholson D., Thornberry N., Rosen A., Casciola Rosen L. Granzyme B directly and efficiently cleaves several downstream caspase substrates: implications for CTL-induced apoptosis. Immunity. 8:1998;451-460.
    • (1998) Immunity , vol.8 , pp. 451-460
    • Andrade, F.1    Roy, S.2    Nicholson, D.3    Thornberry, N.4    Rosen, A.5    Casciola Rosen, L.6
  • 11
    • 0029797971 scopus 로고    scopus 로고
    • Regulation of protein transport to the nucleus: Central role of phosphorylation
    • Jans D. A., Hübner S. Regulation of protein transport to the nucleus: Central role of phosphorylation. Physiol. Rev. 76:1996;651-685.
    • (1996) Physiol. Rev. , vol.76 , pp. 651-685
    • Jans, D.A.1    Hübner, S.2
  • 12
    • 0030913267 scopus 로고    scopus 로고
    • How proteins are transported from the cytoplasm to the nucleus
    • Yoneda Y. How proteins are transported from the cytoplasm to the nucleus. J. Biochem. 121:1997;811-817.
    • (1997) J. Biochem. , vol.121 , pp. 811-817
    • Yoneda, Y.1
  • 13
    • 0029984570 scopus 로고    scopus 로고
    • Nucleocytoplasmic transport
    • Görlich D., Mattaj I. W. Nucleocytoplasmic transport. Science. 271:1996;1513-1518.
    • (1996) Science , vol.271 , pp. 1513-1518
    • Görlich, D.1    Mattaj, I.W.2
  • 17
    • 0025924279 scopus 로고
    • Assessment of cytokines by immunofluorescence and the paraformaldehyde-saponin procedure
    • Sander B., Andersson J., Andersson U. Assessment of cytokines by immunofluorescence and the paraformaldehyde-saponin procedure. Immunol. Rev. 119:1991;65-92.
    • (1991) Immunol. Rev. , vol.119 , pp. 65-92
    • Sander, B.1    Andersson, J.2    Andersson, U.3
  • 18
    • 0013589878 scopus 로고
    • Isolation of subcellular organelles and membranes
    • Washington: Oxford IRL Press. p. 161-182
    • Graham J. Isolation of subcellular organelles and membranes. Centrifugation, a Practical Approach. 1992;Oxford IRL Press, Washington. p. 161-182.
    • (1992) Centrifugation, a Practical Approach
    • Graham, J.1
  • 20
    • 0008263754 scopus 로고
    • Marker enzymes and chemical assays for the analysis of subcellular fractions
    • D. Rickwood. Oxford IRL Press
    • Graham J., Ford T. C. Marker enzymes and chemical assays for the analysis of subcellular fractions. Rickwood D. Centrifugation, a Practical Approach. 1992;309-333 Oxford IRL Press.
    • (1992) Centrifugation, a Practical Approach , pp. 309-333
    • Graham, J.1    Ford, T.C.2
  • 21
    • 0025083331 scopus 로고
    • Nuclear protein import in permeabilized mammalian cells requires soluble cytoplasmic factors
    • Adam S. A., Sterne Marr R., Gerace L. Nuclear protein import in permeabilized mammalian cells requires soluble cytoplasmic factors. J. Cell Biol. 111:1990;807-816.
    • (1990) J. Cell Biol. , vol.111 , pp. 807-816
    • Adam, S.A.1    Sterne Marr, R.2    Gerace, L.3
  • 22
    • 0026723508 scopus 로고
    • The two steps of nuclear import, targeting to the nuclear envelope and translocation through the nuclear pore, require different cytosolic fractions
    • Shannon Moore M., Blobel G. The two steps of nuclear import, targeting to the nuclear envelope and translocation through the nuclear pore, require different cytosolic fractions. Cell. 69:1992;939-950.
    • (1992) Cell. , vol.69 , pp. 939-950
    • Shannon Moore, M.1    Blobel, G.2
  • 24
    • 0024322656 scopus 로고
    • Breast cancer and breastfeeding: Results from an Australian case-control study
    • Siskind V., Schofield F., Rice D., Bain C. Breast cancer and breastfeeding: Results from an Australian case-control study. Am. J. Epidemiol. 130:1989;229-236.
    • (1989) Am. J. Epidemiol. , vol.130 , pp. 229-236
    • Siskind, V.1    Schofield, F.2    Rice, D.3    Bain, C.4
  • 25
    • 0023772439 scopus 로고
    • Infant feeding and childhood cancer
    • Davis M. K., Savitz D. A., Graubard B. I. Infant feeding and childhood cancer. Lancet. 2:1988;365-368.
    • (1988) Lancet , vol.2 , pp. 365-368
    • Davis, M.K.1    Savitz, D.A.2    Graubard, B.I.3
  • 31
    • 0027220867 scopus 로고
    • Alpha-lactalbumin possesses a distinct zinc binding site
    • Ren J., Stuart D. I., Acharya K. R. Alpha-lactalbumin possesses a distinct zinc binding site. J. Biol. Chem. 268:1993;19292-19298.
    • (1993) J. Biol. Chem. , vol.268 , pp. 19292-19298
    • Ren, J.1    Stuart, D.I.2    Acharya, K.R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.