Response of alveolar macrophages from inducible nitric oxide synthase knockout or wild-type mice to an in vitro lipopolysaccharide or silica exposure

Journal of Toxicology and Environmental Health - Part A

Volumn 66, Issue 11, 2003, Pages 995-1013

  Zeidler, Patti C ^a   Roberts, Jenny R ^a   Castranova, Vincent ^a,b   Chen, Fei ^b   Butterworth, Leon ^b   Andrew, Michael E ^b   Robinson, Victor A ^b   Porter, Dale W ^b  

^a WEST VIRGINIA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NATIONAL INSTITUTE FOR OCCUPATIONAL SAFETY AND HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; HYDROGEN PEROXIDE; LIPOPOLYSACCHARIDE; MACROPHAGE INFLAMMATORY PROTEIN 2; NITRATE; NITRIC OXIDE SYNTHASE; NITRITE; REACTIVE OXYGEN METABOLITE; SILICON DIOXIDE; SUPEROXIDE; TUMOR NECROSIS FACTOR ALPHA; ANTIOXIDANT; CYTOKINE; INDUCIBLE NITRIC OXIDE SYNTHASE; NOS2 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL TYPE; CONTROLLED STUDY; GENE DELETION; IMMUNE RESPONSE; INFLAMMATION; KNOCKOUT MOUSE; LUNG ALVEOLUS MACROPHAGE; LUNG DISEASE; LUNG LAVAGE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; STATISTICAL ANALYSIS; WILD TYPE; ANIMAL; CELL COUNT; CONFOCAL MICROSCOPY; CULTURE TECHNIQUE; CYTOLOGY; DRUG EFFECT; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; GENETICS; METABOLISM; MOUSE MUTANT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALIA;

ANIMALS; ANTIOXIDANTS; BRONCHOALVEOLAR LAVAGE FLUID; CELL COUNT; CELL CULTURE TECHNIQUES; CYTOKINES; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; LIPOPOLYSACCHARIDES; MACROPHAGES, ALVEOLAR; MALE; MICE; MICE, KNOCKOUT; MICROSCOPY, CONFOCAL; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; REACTIVE OXYGEN SPECIES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SILICON DIOXIDE;

EID: 0037562754     PISSN: 15287394     EISSN: None     Source Type: Journal    
DOI: 10.1080/15287390306395     Document Type: Article

References (32)

1. Antonini, J. M., Roberts, J. R., Clarke, R. W., Yang, H., Barger, M. W., Ma, J. Y. C., and Weissman, D. N. 2001. Effect of age on respiratory defense mechanisms. Chest 120:240-249.
2. Blackford, J. A., Jr., Jones, W., Dey, R. D., and Castranova, V. 1997. Comparison of inducible nitric oxide synthase gene expression and lung inflammation following intratracheal instillation of silica, coal, carbonyl iron, or titanium dioxide in rats. J. Toxicol. Environ. Health A 51:203-218.
3. Castranova, V. 1998a. Nitric oxide (NO) and organic dusts. Proc. 22nd Cotton Dust and Other Organic Dusts, eds. P. J. Wakelyn, R. R. Jacobs, and R. R. Rylander, pp. 170-180. Memphis, TN: National Cotton Council.
4. Castranova, V. 1998b. Particulates and the airways: Basic biological mechanisms of pulmonary pathogenicity. Appl. Occup. Environ. Hyg. 13:613-616.
5. Castranova, V. 2000. From coal mine dust to quartz: Mechanisms of pulmonary pathogenicity. Inhal. Toxicol. 12(suppl. 3):7-14.
6. Castranova, V., Huffman, L. J., Judy, D. J., Bylander, J. E., Lapp, L. N., Weber, S. L., Blackford, J. A., and Dey, R. D. 1998. Enhancement of nitric oxide production by pulmonary cells following silica exposure. Environ. Health Perspect. 106(suppl. 5):1165-1169.
7. Castranova, V., Jones, T. A., Barger, M. W., Afshari, A., and Frazer, D. G. 1990. Pulmonary responses of guinea pigs to consecutive exposures to cotton dust. Proc. 14th Cotton Dust Res. Conf., eds. R. R. Jacobs, P. J. Wakelyn, and L. N. Domelsmith, pp. 131-135. Memphis, TN: National Cotton Council.
8. Castranova, V., Wright, J. R., Colby, H. D., and Miles, P. R. 1983. Ascorbate uptake by isolated rat alveolar macrophages and type II cells. J. Appl. Physiol. 54:208-214.
9. Chen, F., Kuhn, D. C., Sun, S. C., Gaydos, L. J., and Demers, L. M. 1995. Dependence and reversal of nitric oxide production on NF-kappa B in silica and lipopolysaccharide-induced macrophages. Biochem. Biophys. Res. Commun. 214:839-846.
10. Chen, F., Sun, S.-C., Kuhn, D. C., Gaydos, L. J., and Demers, L. M. 1995. Essential role of NF-κB activation in silica-induced inflammatory mediator production in macrophages. Biochem. Biophys. Res. Commun. 214:985-992.
11. Ding, M., Shi, X., Lu, Y., Huang, C., Leonard, S., Roberts, J., Antonini, J., Castranova, V., and Vallyathan, V. 2001. Induction of activator protein-1 through reactive oxygen species by crystalline silica in JB6 cells. J. Biol. Chem. 276:9108-9114.
12. Driscoll, K. E., Higgins, J. M., Leytart, M. J., and Crosby, L. L. 1990. Differential effects of mineral dusts on the in vitro activation of alveolar macrophages eicosanoid and cytokine release. Toxicol. In vitro 4:284-288.
13. Dubois, C. M., Bissonnette, E., and Rola-Pleszczynski, M. 1989. Asbestos fibers and silica particles stimulate rat alveolar macrophages to release tumor necrosis factor. Autoregulatory role of leukotriene B4. Am. Rev. Respir. Dis. 139:1257-1264.
14. Flick, D. A., and Gifford, G. E. 1984. Comparison of in vitro cell cytotoxic assays for tumor necrosis factor. J. Immunol. Methods 68:167-175.
15. Fujii, H., Ichimori, K., Hoshiai, K., and Nakazawa, H. 1997. Nitric oxide inactivates NADPH oxidase in pig neutrophils by inhibiting its assembling process. J. Biol. Chem. 272:32773-32778.
16. Gaston, B., Drazen, J. M., Loscalzo, J., and Stamler, J. S. 1994. The biology of nitrogen oxides in the airways. Am. J. Respir. Crit. Care Med. 149:538-551.
17. Huffman, L. J., Judy, D. J., and Castranova, V. 1998. Regulation of nitric oxide production by rat alveolar macrophages in response to silica exposure. J. Toxicol. Environ Health A 53:29-46.
18. Kang, J. L., Go, Y. H., Hur, K. C., and Castranova, V. 2000. Silica-induced nuclear factor-κB activation: Involvement of reactive oxygen species and protein tyrosine kinase activation. J Toxicol Environ Health A 60:27-46.
19. Kang, J. L., Lee, K., and Castranova, V. 2000. Nitric oxide up-regulates DNA-binding activity of nuclear factor-κB in macrophages stimulated with silica and inflammatory stimulants. Mol. Cell Biochem. 215:1-9.
20. Kobzik, L., Bredt, D. S., Lowenstein, C. J., Drazen, J., Gaston, B., Sugarbaker, D., and Stamler, J. S. 1993. Nitric oxide synthase in human and rat lung: Immunocytochemical and histochemical localization. Am. J. Respir. Cell Mol. Biol. 9:371-377.
21. Laubach, V. E., Shesely, E. G., Smithies, O., and Sherman, P. A. 1995. Mice lacking inducible nitric oxide synthase are not resistant to lipopolysaccharide-induced death. Proc. Natl. Acad. Sci. USA 92:10688-10692.
22. Mayeux, P. R. 1997. Pathobiology of lipopolysaccharide. J. Toxicol. Environ. Health A 51:415-435.
23. Miles, P. R., Bowman, L., Rengasamy, A., and Huffman, L. 1997. Alveolar type II cell cNOS activity and ATP levels are increased by lung surfactant or DPPC vesicles. Am. J. Physiol. 273:L339-L346.
24. Miles, P. R., Bowman, L., Rengasamy, A., and Huffman, L. 1998. Constitutive nitric oxide production by rat alveolar macrophages. Am. J. Physiol. 274:L360-L368.
25. Porter, D. W., Millecchia, L., Robinson, V. A., Hubbs, A., Willard, P., Pack, D., Ramsey, D., McLaurin, J., Khan, A., Landsittel, D., Teass, A., and Castranova, V. 2002. Enhanced nitric oxide and reactive oxygen species production and damage after inhalation of silica. Am. J. Physiol. Lung Cell Mol. Physiol. 283:L485-L493.
26. Rao, M. 2000. Molecular mechanisms regulating iNOS expression in various cell types. J Toxicol Environ Health B 3:27-58.
27. Rodenas, J., Mitjavila, M. T., and Carbonell, T. 1998. Nitric oxide inhibits superoxide production by inflammatory polymorphonuclear leukocytes. Am. J. Physiol. 274:C827-C830.
28. Rubbo, H., Radi, R., Trujillo, M., Telleri, R., Kalyanaraman, B., Barnes, S., Kirk, M., and Freeman, B. A. 1994. Nitric oxide regulation of superoxide and peroxynitrite-dependent lipid peroxidation. Formation of novel nitrogen-containing oxidized lipid derivatives. J. Biol. Chem. 269:26066-26075.
29. Sadick, M. D., Intintoli, A., Quarmby, V., McCoy, A., Canova-Davis, E., and Ling, V. 1999. Kinase receptor activation (KIRA): A rapid and accurate alternative to end-point bioassays. J. Pharm. Biomed. Anal. 19:883-891.
30. Saffiotti, U., Williams, O., Daniel, L. N., Kaighn, M. E., Mao, Y., and Shi, X. 1996. Carcinogenesis by crystalline silica: Animal, cellular, and molecular studies. In Silica and silica-induced lung diseases, eds. V. Castranova, V. Vallyathan, and W. E. Wallace, pp. 345-381. Boca Raton, FL: CRC Press.
31. Zamzami, N., Marchetti, P., Castedo, M., Decaudin, D., Macho, A., Hirsch, T., Susin, S. A., Petit, P. X., Mignotte, B., and Kroemer, G. 1995. Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death. J. Exp. Med. 182:367-377.
32. Zamzami, N., Marchetti, P., Castedo, M., Zanin, C., Vayssiere, J. L., Petit, P. X., and Kroemer, G. 1995. Reduction in mitochondrial potential constitutes an early irreversible step of programmed lymphocyte death in vivo. J. Exp. Med. 181:1661-1672.