Effect of age on respiratory defense mechanisms: Pulmonary bacterial clearance in Fischer 344 rats after intratracheal instillation of Listeria monocytogenes

Chest

Volumn 120, Issue 1, 2001, Pages 240-249

  Antonini, James M ^a   Roberts, Jenny R ^a   Clarke, Robert W ^b   Yang, Hui Min ^a   Barger, Mark W ^a   Ma, Jane Y C ^a   Weissman, David N ^a  

^a NATIONAL INSTITUTE FOR OCCUPATIONAL SAFETY AND HEALTH   (United States)

^b HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

Age; Chemiluminescence; Host defense; Listeria monocytogenes; Macrophage; Nitric oxide; Pulmonary clearance

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; NITRIC OXIDE;

AGE; AGED; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL COUNT; CHEMOLUMINESCENCE; CONTROLLED STUDY; IMMUNITY; INFECTION SENSITIVITY; INOCULATION; LISTERIA MONOCYTOGENES; LUNG ALVEOLUS MACROPHAGE; LUNG CLEARANCE; LUNG EDEMA; LUNG INFECTION; LUNG INJURY; LUNG LAVAGE; MALE; MORTALITY; NONHUMAN; PRIORITY JOURNAL; RAT; RESPIRATORY SYSTEM; T LYMPHOCYTE;

EID: 0034880889     PISSN: 00123692     EISSN: None     Source Type: Journal    
DOI: 10.1378/chest.120.1.240     Document Type: Article

References (38)

1. Immunology of the aging lung
2. Geriatric respiratory medicine
3. Age-related decrease in accessory cell function of human alveolar macrophages
4. Bacterial pneumonia in the elderly
5. Morphologic basis of pulmonary resistance in the human lung and effects of aging
6. 2 on the lungs of aging rats: II. Cell proliferation
7. Cellular kinetics in the lungs of aging Fischer 344 rats after acute exposure to ozone
8. Endotoxin priming affects the lung response to ultrafine particles and ozone in young and old rats
9. Induction of adaption to inhaled lipopolysaccharide in young and old rats and mice
10. Effect of aging on nitric oxide production by rat alveolar macrophages
11. +) in the lung increases with age in both humans and rats
12. Review of epidemiologic evidence of health effects of particulate air pollution
13. The toxicologic interactions resulting from inhalation of carbon black and acrolein on pulmonary antibacterial and antiviral defenses
14. Effects of ozone on the defense to a respiratory Listeria monocytogenes infection in the rat
15. Surface morphology and morphometry of rat alveolar macrophages after ozone exposure
16. Effects of amiodarone-induced phospholipidosis on pulmonary host defense functions in rats
17. Response to Listeria monocytogenes in mice lacking MHC class Ia molecules
18. Listeria monocytogenes as a probe to study cell-mediated immunity
19. Pulmonary distribution of particles given by intratracheal instillation or by aerosol inhalation
20. Scaling of respiratory variables in mammals
21. Introduction of luminol-dependent chemiluminescence as a method to study silica inflammation in the tissue and phagocytic cells of rat lung
22. Pulmonary responses of guinea pigs to consecutive exposures to cotton dust
23. Analysis of nitrate, nitrite, and [15N] nitrate in biological fluids
24. Development of a testing battery to assess chemical-induced immunotoxicity: National Toxicology Program's guidelines for immunotoxicity evaluation in mice
25. The relation of age to the numbers of lung free cells, lung weight, and body weight in rats
26. Age-related morphometric differences in responses to rat lungs to ozone
27. Age-related responses in rats to concentrated urban air particles (CAPs)
28. State of the art: Mucociliary clearance in the airways
29. Influenza virus infection and bacterial clearance in young adult and aged mice
30. The aging immune system: Primer and prospectus
31. Host defense mechanisms and aging
32. Functional identity of murine interferon and macrophage activating factor
33. IFN-γ and IL-4 regulate the growth and differentiation of CD8+ T cells into subpopulations with distinct cytokine profiles
34. Oxidant release from pulmonary phagocytes
35. Regulation of biosynthesis of nitric oxide
36. The role of nitric oxide in inflammation
37. The chemistry of peroxynitrite: A product from the reaction of nitric oxide with superoxide
38. Surfactant protein A mediates mycoplasmacidal activity of alveolar macrophages by production of peroxynitrite