Quantitative account of the enhanced affinity of two linked scFvs specific for different epitopes on the same antigen

Journal of Molecular Biology

Volumn 329, Issue 1, 2003, Pages 1-8

  Zhou, Huan Xiang ^a  

^a Florida State University   (United States)

Author keywords

Affinity enhancement; Antibody engineering; Bi specific antibody; Flexible linker; Non overlapping epitopes

Indexed keywords

ANTIBODY; ANTIGEN; DNA BINDING PROTEIN; EPITOPE; LYSOZYME; PEPTIDE; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY;

ANTIBODY ENGINEERING; ANTIGEN BINDING; ARTICLE; BINDING AFFINITY; EGG; HEN; PREDICTION; PRIORITY JOURNAL; PROBABILITY; PROTEIN PROTEIN INTERACTION; QUANTITATIVE ANALYSIS; THEORY;

EID: 0037540052     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-2836(03)00372-3     Document Type: Article

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