Cyclooxygenase-2 expression in canine mammary tumors

Veterinary Pathology

Volumn 40, Issue 2, 2003, Pages 207-212

  Dore M ^a   Lanthier, I ^b   Sirois, J ^b  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

^b NONE

Author keywords

Cyclooxygenase 2; Dogs; Mammary tumors; Prostaglandins

Indexed keywords

CYCLOOXYGENASE 2; ISOENZYME; PROSTAGLANDIN SYNTHASE;

ANIMAL TISSUE; ARTICLE; BREAST ADENOCARCINOMA; BREAST ADENOMA; BREAST TUMOR; CONTROLLED STUDY; DOG; IMMUNOHISTOCHEMISTRY; INCIDENCE; NONHUMAN; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; ADENOCARCINOMA; ADENOMA; ANIMAL; ANIMAL DISEASE; BIOSYNTHESIS; DOG DISEASE; ENZYMOLOGY; EXPERIMENTAL NEOPLASM; FEMALE; PATHOLOGY;

ANIMALIA; CANIS FAMILIARIS;

ADENOCARCINOMA; ADENOMA; ANIMALS; CYCLOOXYGENASE 2; DOG DISEASES; DOGS; FEMALE; IMMUNOHISTOCHEMISTRY; ISOENZYMES; MAMMARY NEOPLASMS, ANIMAL; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES;

EID: 0037532395     PISSN: 03009858     EISSN: None     Source Type: Journal    
DOI: 10.1354/vp.40-2-207     Document Type: Article

References (27)

1. Cohen D, Reif JS, Brodey RS, Keiser H: Epidemiological analysis of the most prevalent sites and types of canine neoplasia observed in a veterinary hospital. Cancer Res 34:2859-2868, 1974
2. DeWitt DL: Cox-2 selective inhibitors: the new super aspirins. Mol Pharmacol 55:625-631, 1999
3. Gilbertson SR, Kurzman ID, Zachrau RE, Hurvitz AI, Black MM: Canine mammary epithelial neoplasms: biologic implications of morphologic characteristics assessed in 232 dogs. Vet Pathol 20:127-142, 1983
4. Half E, Ming Tang X, Gwyn K, Sahin A, Wathen K, Sinicrope FA: Cyclooxygenase-2 expression in human breast cancers and adjacent ductal carcinoma in situ. Cancer Res 62:1676-1681, 2002
5. Harris RE, Alshafie GA, Abou-Issa H, Seibert K: Chemoprevention of breast cancer in rats by celecoxib, a cyclooxygenase 2 inhibitor. Cancer Res 60:2101-2103, 2000
6. Howe LR, Subbaramaiah K, Brown AMC, Dannenberg AJ: Cyclooxygenase-2: a target for the prevention and treatment of breast cancer. Endocr Relat Cancer 8:97-114, 2001
7. Hwang D, Scollard D, Byrne J, Levine E: Expression of cyclooxygenase-1 and cyclooxygenase-2 in human breast cancer. J Natl Cancer Inst 90:455-460, 1998
8. Khan KN, Knapp DW, Denicola DB, Harris RK: Expression of cyclooxygenase-2 in transitional cell carcinoma of the urinary bladder in dogs. Am J Vet Res 61: 478-481, 2000
9. Khan KN, Stanfield KM, Trajkovic D, Knapp DW: Expression of cyclooxygenase-2 in canine renal cell carcinoma. Vet Pathol 38:116-119, 2001
10. Knapp DW, Richardson RC, Bottoms GD, Teclaw R, Chan TCK: Phase I trial of piroxicam in 62 dogs bearing naturally occurring tumors. Cancer Chemother Pharmacol 29:214-218, 1992
11. Krajewska M, Krajewski S, Epstein JI, Shabaik A, Sauvageot J, Song K, Kitada S, Reed J: Immunohistochemical analysis of bcl-2, bax, bcl-x, and mcl-1 expression in prostate cancers. Am J Pathol 148:1567-1576, 1996
12. Liu CH, Chang SH, Narko K, Trifan OC, Wu MT, Smith E, Haudenschild C, Lane TF, Hla T: Overexpression of cyclooxygenase-2 is sufficient to induce tumorigenesis in transgenic mice. J Biol Chem 276:18563-18569, 2001
13. Misdorp W, Else RW, Hellmén E, Lipscomb TP: Histological classification of mammary tumors of the dog and the cat. In: Bulletin of The World Health Organization, International Histological Classification of Tumors of Domestic Animals, 2nd series, vol. VII, pp. 18-25. Washington, DC, 1999
14. 2 concentrations in naturally occurring canine cancer. Prostaglandins Leukot Essent Fatty Acids 64:1-4, 2001
15. Moulton JE: Tumors of the skin and soft tissues. In: Tumors in Domestic Animals, ed. Moulton JE, 3rd ed., p. 23. University of California Press, Los Angeles, CA, 1990
16. Muto T, Wakui S, Takahashi H, Maekawa S, Masaoka T, Ushigome S, Furusato M: p53 gene mutations occurring in spontaneous benign and malignant mammary tumors of the dog. Vet Pathol 37:248-253, 2000
17. Pestili de Almeida EM, Piché C, Sirois J, Doré M: Expression of cyclo-oxygenase-2 in naturally occurring squamous cell carcinomas in dogs. J Histochem Cytochem 49:867-875, 2001
18. Ristimäki A, Sivula A, Lundin J, Lundin M, Salminen T, Haglund C, Joensuu H, Isola J: Prognostic significance of elevated cyclooxygenase-2 expression in breast cancer. Cancer Res 62:632-635, 2002
19. Schneider R, Dorn CR, Taylor DO: Factors influencing canine mammary cancer development and postsurgical survival. J Natl Cancer Inst 43:1249-1261, 1969
20. Schreinemachers DM, Everson RB: Aspirin use and lung, colon, and breast cancer incidence in a prospective study. Epidemiology 5:138-146, 1994
21. Smith WL: Prostanoid biosynthesis and mechanisms of action. Am J Physiol 263:F181-F191, 1992
22. Soslow RA, Dannenberg AJ, Rush D, Woerner BM, Khan KN, Masferrer J, Koki AT: COX-2 is expressed in human pulmonary, colonic, and mammary tumors. Cancer 89:2637-2645, 2000
23. Taketo MM: Cyclooxygenase-2 inhibitors in tumorigenesis. J Natl Cancer Inst 90:1609-1620, 1998
24. Tremblay C, Doré M, Bochsler PN, Sirois J: Induction of prostaglandin G/H synthase-2 in a canine model of spontaneous adenocarcinoma. J Natl Cancer Inst 9:1398-1403, 1999
25. van der Ouderaa FJ, Buytenhek M, Slikkerveer FJ, van Dorp DA: On the haemoprotein character of prostaglandin endoperoxide synthetase. Biochim Biophys Acta 572:29-42, 1979
26. van Garderen E, de Wit M, Voorhout WF, Rutteman GR, Mol JA, Nederbragt H, Misdorp: Expression of growth hormone in canine mammary tissue and mammary tumors. Evidence for a potential autocrine/paracrine stimulatory loop. Am J Pathol 150:1037-1047, 1997
27. Williams CS, DuBois RN: Prostaglandin endoperoxide synthase: why two isoforms? Am J Physiol 270:G393-G400, 1996