Competition between two MHC binding registers in a single peptide processed from myelin basic protein influences tolerance and susceptibility to autoimmunity

Journal of Experimental Medicine

Volumn 197, Issue 10, 2003, Pages 1391-1397

  Seamons, Audrey ^a   Sutton, Jennifer ^b   Bai, Dina ^b   Baird, Emily ^a   Bonn, Nena ^a   Kafsack, Björn F C ^a   Shabanowitz, Jeffrey ^b   Hunt, Donald F ^b,c   Beeson, Craig ^a   Goverman, Joan ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

^b UNIVERSITY OF VIRGINIA   (United States)

^c UNIVERSITY OF VIRGINIA   (United States)

Author keywords

Antigen processing; Experimental allergic encephalomyelitis; MBP epitopes; MHC class II; T cell tolerance

Indexed keywords

EPITOPE; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MYELIN BASIC PROTEIN;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL CELL; ANTIGEN PRESENTATION; ANTIGEN PRESENTING CELL; ARTICLE; AUTOIMMUNITY; BINDING AFFINITY; CONTROLLED STUDY; IMMUNOLOGICAL TOLERANCE; MAJOR HISTOCOMPATIBILITY COMPLEX; MASS SPECTROMETRY; MOUSE; MULTIPLE SCLEROSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN EXPRESSION; T LYMPHOCYTE;

ANIMALS; ANTIGEN PRESENTATION; AUTOIMMUNITY; BINDING, COMPETITIVE; EPITOPES; HISTOCOMPATIBILITY ANTIGENS CLASS II; IMMUNE TOLERANCE; MICE; MYELIN BASIC PROTEINS; PEPTIDE FRAGMENTS; T-LYMPHOCYTES;

EID: 0037515456     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.20022226     Document Type: Article

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